<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation I93L
Rx PI-naive
IncludeMixtures No
References 17
Patients 81
Isolates 81
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cuevas (2002)CU13CU13AF425394None   L19I, E35D, N37T, I62V, L63P, I72V, I93LG
Fonjungo (2002)CM239CM239AY051209None   T12K, I13V, K20I, E35D, M36I, R41K, I64M, C67E, H69K, V82I, L89M, I93LG
 CM218CM218AY051208None   L10I, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, K70R, V82I, L89M, I93LG
 CM182CM182AY051207None   I13V, K14R, K20I, M36I, R41K, I64L, H69K, V82I, L89M, I93LG
 CM171CM171AY051206None   T12A, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K45R, R57K, L63P, C67E, H69K, V82I, L89M, I93LG
 CM162CM162AY051205None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, V82I, L89M, I93LG
 CM16CM16AY051204None   L10I, T12P, I13V, I15V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
 CM129CM129AY051203None   L10I, I13V, K14R, I15V, G16E, K20I, M36I, N37S, R41K, L63V, I64L, C67S, H69K, L89M, I93LG
Non-B Workgroup (2005)PL3201464894AY901042None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, I72IV, T74S, L89I, I93LG
 PL32676102203 None   I13V, L19I, K20I, E35D, M36I, R41K, H69K, T74A, V82I, L89M, I93LG
 PL4512280255 None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69K, T74A, L89M, I93LG
 PL5209098374 None   L10LI, T12TA, I13V, K14R, K20I, E34Q, E35D, M36I, R41K, L63P, G68E, H69K, V77VI, V82VI, L89M, I93LG
Zeh (2005)99NG107599NG1075AY103364None   L10I, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, C67E, H69Q, V82I, L89M, I93LG
 99NG127599NG1275AY103374None   I13V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
 99NG73599NG735AY103387None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG74799NG747AY103388None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
 99NG77999NG779AY103391None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
 99NG86999NG869AY103396None   I13V, K14R, I15V, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, G68R, H69K, G73R, V82I, G86R, L89M, I93LG
 99NG105699NG1056AY103362None   L10I, I13V, K14R, I15V, Q18R, K20I, E35Q, M36I, N37D, R41K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG106199NG1061AY103363None   L10M, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG107799NG1077AY103365None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89M, I93LG
 99NG108199NG1081AY103366None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, C67E, H69K, V82I, L89M, I93LG
 99NG117999NG1179AY103367None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, C67E, H69K, V82I, L89M, I93LG
 99NG118999NG1189AY103368None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, K70R, V82I, L89M, I93LG
 99NG11999NG119AY103369None   L10I, I13V, K14R, I15V, Q18R, K20I, E35Q, M36I, N37D, R41K, C67E, H69K, V82I, L89M, I93LG
 99NG122199NG1221AY103370None   I13V, K20I, M36I, R41K, C67G, H69K, V82I, L89M, I93LG
 99NG125399NG1253AY103371None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89M, I93LG
 99NG126999NG1269AY103372None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
 99NG127199NG1271AY103373None   I13V, K20I, E35Q, M36I, R57K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG128399NG1283AY103375None   L10M, I13V, K20I, E35Q, M36I, R41K, C67E, H69K, L89M, I93LG
 99NG129799NG1297AY103376None   L10M, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
 99NG130599NG1305AY103377None   I13V, K14R, L19I, K20I, E35Q, M36I, N37D, R41K, R57K, C67K, H69K, V82I, G86R, R87K, L89M, I93LG
 99NG130999NG1309AY103378None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, I64M, C67E, H69K, V82I, L89M, I93LG
 99NG23999NG239AY103380None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG33599NG335AY103381None  G48ER8Q, I13V, K14R, K20I, E35Q, M36I, R41K, G51E, G52E, R57K, D60N, C67K, H69K, V82I, L89M, T91A, I93LG
 99NG62199NG621AY103382None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
 99NG61999NG619AY103383None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, I62V, L63S, C67E, H69K, V82I, L89M, I93LG
 99NG62399NG623AY103384None   T12A, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG66399NG663AY103385None   I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89M, I93LG
 99NG66899NG668AY103386None   L10I, I13V, K14R, I15V, Q18R, K20I, E35Q, M36I, N37D, R41K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG76599NG765AY103389None   I13V, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG76999NG769AY103390None   I13V, K14R, L19I, K20I, E35Q, M36I, R41K, R57K, Q61H, C67E, H69K, V82I, L89M, I93LG
 99NG78299NG782AY103392None   I13V, K14R, K20I, E35D, M36I, R41K, R57K, L63S, C67E, H69K, V82I, L89M, I93LG
 99NG78999NG789AY103393None   L10I, I13V, K14R, I15V, Q18R, K20I, E35Q, M36I, N37D, R41K, C67E, H69K, V82I, L89M, I93LG
 99NG82799NG827AY103394None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
 99NG86199NG861AY103395None   I13V, K14R, I15V, K20V, E35Q, M36I, R41K, R57K, I62V, L63P, I64M, C67E, H69K, K70R, V82I, L89M, I93LG
 99NG88199NG881AY103397None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V77I, V82I, L89M, I93LG
 99NG88399NG883AY103398None   L10M, V11A, I13V, K20I, E35Q, M36I, R41K, R57K, Q61E, C67E, H69K, V82I, L89M, I93LG
 99NG88999NG889AY103399None   I13V, K14R, L19I, K20I, E35Q, M36I, N37D, R57K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG89099NG890AY103400None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, L63H, C67E, H69K, V82I, L89M, I93LG
 99NG89399NG893AY103401None   I13V, L19I, K20I, E35Q, M36I, R41K, R57K, Q61E, C67E, H69K, V82I, L89M, I93LG
 99NG89999NG899AY103402None   I13V, K14R, I15V, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG90999NG909AY103403None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, I62V, L63P, C67E, H69K, V82I, L89M, I93LG
Ndongmo (2006)CM38CBN_CM38DQ394166None   I13V, K14R, G17E, K20I, M36I, C67E, H69K, V82I, L89M, I93LG
Niama (2006)ARV56ARV56FM164890None   T12K, I13V, K20I, M36I, N37D, R41K, Q61E, I62V, L63P, C67E, H69K, I93LG
Gatanaga (2007)C04-51110202-1C04-51110202-1AB640302None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, Q61E, L63P, C67E, H69K, V82I, L89M, I93LG
 C04-51110203-1C04-51110203-1AB640303None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, Q61E, L63P, C67E, H69K, V82I, L89M, I93LG
Palma (2007)Pt4376045 None   I13V, K14R, K20I, E35DN, M36I, R41K, I64IM, C67E, H69K, T74TA, V82I, L89M, I93LG
 Pt7897042 None   T12TA, I13V, K14KR, K20I, E35D, M36I, R41K, H69K, A71V, V82I, L89M, I93LG
 Pt127111055 None   I13V, K14R, I15V, K20I, E35EDG, M36I, R41K, L63P, C67E, H69K, V82I, L89M, I93LG
 Pt148120500 None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63T, C67S, H69K, T74S, V82I, L89M, I93LG
 Pt162124958 None   I13V, K14R, I15V, G16E, K20M, E35D, M36I, R41K, L63Q, H69K, V82I, L89I, I93LG
 Pt172128147 None   I13A, K14R, I15V, L19I, K20I, E34Q, E35D, M36I, R41K, L63P, H69K, V82I, L89I, I93LG
 Pt183132028 None  V11VII13V, K14R, K20I, E34Q, E35D, M36I, R41K, H69K, V82I, L89M, I93LG
 Pt212137816 None   I13A, K14KR, I15V, L19I, K20I, E34Q, E35D, M36I, R41K, L63P, H69K, K70KR, V82I, L89I, I93LG
 Pt221139995 None   I13V, K14R, K20I, E34Q, E35D, M36I, R41K, G68GE, H69K, K70R, V82I, L89M, I93LG
 Pt223140067 None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, I64L, H69K, V82I, L89M, I93LG
Zhong (2007)D005205CN_052EF199585None   I13V, K20I, E35D, M36I, Q61E, L63P, I64L, C67S, H69K, V82I, L89M, I93LG
Vercauteren (2009)pt17622808401305GQ399262None   I13V, K14R, K20I, M36L, R41K, I64L, C67E, H69K, V82I, L89M, I93LG
 pt17003150049452GQ399324None   I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89M, I93LG
Wallis (2009)23464402346440 None   T12S, I15V, E35D, M36I, R41K, D60E, H69K, L89I, I93LG
Hattori (2010)A08-201084A08-201084AB863818None   T12P, I13V, K20I, M36I, R41K, L63P, I64L, C67S, H69R, V82I, L89M, I93LG
Hamers (2011)300441CP076300441HM119863None   I3V, L10I, G16A, M36I, N37D, R41K, K43R, D60N, Q61D, C67E, H69K, T74S, L89M, I93LG
Karlsson (2012)SE_125SE_125JQ698754None   I13V, K14R, K20I, E35G, M36I, P39S, R41K, H69K, T74S, V82I, L89M, I93LG
Machado (2012)CUPL1027CUPL1027HQ655404None  V11IL10I, I13V, K20I, M36I, N37S, R41K, I64M, H69K, V82I, L89M, I93LG
 CUPL1083CUPL1083JN000055None   L10I, I13V, K14R, I15V, L19I, K20I, E35D, M36I, L63P, H69K, L89M, T91V, I93LG
 CUPL1150CUPL1150JX194229None   I13V, K14R, K20I, M36I, R41K, H69K, T74S, V82I, L89M, I93LG
Telan (2013)1106382211063822AB747478None   I13V, L19I, K20I, M36I, R41K, Q61E, L63P, I64M, C67S, H69K, V82I, L89M, I93LG
 1203209912032099AB747543None   I13V, K20R, M36I, R41K, C67E, H69K, K70R, V82I, L89M, I93LG
Meixenberger (2014)09-0079609-00796KJ770943None   I13V, K20I, E35Q, M36I, R41K, R57K, L63LP, I64M, C67E, H69K, V82I, L89M, I93LG
 11-0265311-02653KJ771556None   I13V, I15V, K20I, E35Q, M36I, R41K, R57K, I64M, C67E, H69K, V82I, L89M, I93LG