<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L90M
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 82
Isolates 92
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cuevas (2002)CU75CU75AF425456SQV L90MF53L, L89VL10V, I13V, K20I, M36I, R41K, Q61E, H69K, K70R, A71V, T74SG
Montes (2004)MB_patHEN01_HEN734AJ577913NFV, LPV62I54V, L90M I13V, K20I, E35G, M36I, R41K, H69K, K70R, V82I, L89MG
  02_HEN716AJ577914NFV, LPV85I54V, L90MQ58EI13V, K20I, E35G, M36I, R41K, H69K, K70R, V82I, L89IG
 MB_patGRA00_GRA703AJ577905NFV, SQV, LPV107M46L, I54V, L90M I13V, K14R, K20I, E35D, M36I, R41K, I64M, C67E, H69K, A71V, I72V, T74S, V82I, L89I, I93LG
 MB_patPAL99_PAL710AJ577967SQV, RTV, NFV130D30N, M46L, L90ML33I, N88D, L89VI13V, K20I, M36I, L63P, C67S, H69K, A71VG
  01_PAL708AJ577968SQV, RTV, NFV251D30N, M46L, I54V, L90ML33I, N88D, L89VI13V, K20I, M36I, N37K, L63P, C67S, H69K, A71VG
Non-B Workgroup (2005)PL834456514AY900711IDV173M46MI, L90M I13V, K14R, K20I, E35D, M36I, R41K, H69K, V77VI, L89IMG
 PL875856741AY900713SQV, RTV, IDV229G48M, I54V, V82T, L90MF53LI13V, K14R, K20I, E35D, M36I, R41K, Q61H, H69K, A71V, L89IG
 PL3476656768AY900714NFV73L90M I13V, K20I, E35N, M36I, R41K, H69K, K70R, A71T, V82I, L89IG
 PL529657203AY900717SQV, NFV, IDV I54V, V82M, L90MF53LI13A, K14R, I15V, K20I, E35D, M36I, R41K, I62IV, C67CW, H69K, T74A, L89IG
 PL3510257431AY900721SQV, NFV, IDV181I54V, L90MF53LI13V, K14KR, K20IV, L33LV, E35D, M36I, R41K, D60E, I62V, L63P, H69K, A71V, T74S, V82I, L89IG
 PL3379057583AY900722NFV I54V, L90ML33LII13V, K14R, K20IT, E35D, M36I, N37D, R41K, H69K, V82I, L89IG
 PL1087759219AY900976IDV, SQV I54V, V82T, L90M L10LI, I13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, L63LP, H69K, A71V, T74S, L89I, T91TN, T96TNG
 PL3606959512AY900981NFV I54V, L90M I13V, K20I, E35N, M36I, N37ND, R41K, H69K, T74S, V82I, L89IG
 PL3655160625AY900985NFV L90M I13V, K14R, G17E, K20I, E35N, M36I, R41K, I62V, L63P, H69K, K70R, A71T, V82I, L89IG
 PL848759877AY900987SQV L90MF53LL10LI, I13V, K14R, K20I, E35D, M36I, R41K, M46X, I62IV, L63LP, H69K, A71X, T74S, V82I, L89XG
 PL3694361481AY900991NFV73I54IV, L90M I13V, K14R, I15V, K20IV, E35DN, M36I, R41K, H69K, A71T, T74S, V82I, L89IG
 PL3679561171AY900999NFV L90M L10I, I13V, K14R, K20I, E35D, M36I, R41K, R57K, H69K, V82I, L89MG
 PL410862261AY901001NFV L90M I13V, K14R, K20I, E35EG, M36I, R41RK, H69K, A71AT, V82I, L89IG
 PL1937462204AY901002IDV, NFV L90M I13V, K14R, K20I, E35DN, M36I, R41K, H69K, V82I, L89IMG
 PL86262513AY901003IDV, ATV I54V, V82T, L90M I13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, K70R, A71V, T74S, L89IG
 PL2647363176AY901007SQV, NFV, IDV, RTV, LPV I54V, V82F, L90ML89VL10I, I13V, K14R, K20I, E35N, M36I, N37ND, R41K, L63P, H69K, A71V, Q92QKG
  89488 SQV, NFV, IDV, RTV, LPV, UnknownNAM46I, I50V, I54V, V82F, L90ML89VL10I, I13A, K14R, K20IT, A22AV, E35N, M36I, N37D, R41K, L63P, I66V, C67CR, H69K, K70KT, A71V, I85IV, Q92KG
 PL3729062297AY901009NFV87I54V, L90M I13V, K20T, E35D, M36I, R41K, H69K, V82I, L89IG
 PL2529062869AY901010SQV L90M I13V, K20I, E35D, M36I, N37NS, R41K, L63P, H69K, K70R, A71AV, V82I, L89MG
 PL2430163125AY901013NFV, RTV, IDV173I54V, I84V, L90M I13V, K14R, K20I, E35D, M36I, R41K, I62IV, L63P, H69K, A71V, T74S, L89IG
 PL1945463189AY901014Unknown, LPV>22M46L, G48GV, I54V, L90ML89VT4TS, L10LV, I13V, K14R, K20I, M36I, N37D, R41EK, I62V, H69K, A71V, T74S, V82XG
 PL3820164222AY901019SQV, IDV M46MI, I54V, V82M, L90M I13AV, K14R, I15IV, K20I, E35D, M36I, N37D, R41K, L63LP, H69K, K70R, L89IG
 PL2397263353AY901021NFV L90M I13V, K14R, K20I, E35X, M36I, R41K, I62IV, I64IV, I66IF, H69K, K70KR, V82I, L89I, Q92QK, I93ILG
 PL881364115AY901027SQV, NFV204L90MF53L, L89VI13V, K14KR, K20I, E35D, M36I, R41K, L63P, H69K, A71V, V82IG
 PL3844864783AY901029NFV L90M I13V, K14R, K20I, E35EG, M36I, R41K, D60E, L63P, H69K, T74S, V82I, L89M, I93LG
 PL3835164549AY901030NFV L90ML89VI13V, K14R, K20I, E35DG, M36I, R41K, H69K, A71T, V82IG
 PL2745264378AY901034SQV L90MF53LI13V, K14R, K20I, E35D, M36I, R41K, H69K, A71V, V82I, L89IG
 PL3857565077AY901037NFV169L90M I13V, K14R, I15V, K20IV, E35N, M36I, R41K, H69K, K70KR, A71T, V82I, L89IG
 PL888465233AY901039SQV, IDV, LPV M46I, I54V, L76V, L90MF53L, L89VL10I, I13A, K14R, I15IV, K20I, E35D, M36I, R41K, Q61QH, L63P, H69K, A71IT, V82X, T91TSG
 PL1003066215AY901040SQV, IDV I54V, V82A, L90MF53LL10I, I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63P, C67CF, H69K, A71V, L89IG
 PL3865565229 NFV, IDV, RTV L90M I13V, K20I, E35N, M36I, R41K, L63C, H69K, V82I, L89MG
 PL3595467123AY901045SQV, IDV, NFV I54V, L90M I13V, K14R, K20I, E35N, M36I, R41K, K45R, H69K, A71AV, V82I, L89IG
 PL3311666967AY901052NFV M46I, L90M I13V, K20IV, E35DN, M36I, R41K, I64V, H69K, K70KR, A71AV, V82I, L89IM, I93MG
 PL846867575 RTV74I54V, L90MQ58EI13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, V82I, L89MG
 PL3980567858AY901056NFV117I54V, L90M I13V, K14R, K20IT, E35DN, M36I, R41K, H69K, V82I, L89IG
 PL985667800AY901068NFV, RTV M46I, I54V, L90M I13V, K14R, I15V, K20T, E35DN, M36I, R41K, I62V, H69K, T74A, V82I, L89I, I93LG
 PL4041269106AY901069IDV117I54V, V82M, L90M I13V, K20I, E35D, M36I, R41K, L63LP, H69K, L89IG
 PL3690261392AY901077PINAL90M T12TP, I13V, K14R, I15V, K20T, E35D, M36I, R41K, H69K, K70R, A71T, T74S, V82I, L89IG
 TK2013TK2013 IDV, SQV, RTV, NFV196M46I, I54V, L90M L10I, I13V, I15V, K20I, E35D, M36I, N37D, R41K, R57K, Q61H, I66F, H69K, V82I, L89M, Q92KG
  TK2013a IDV, SQV, RTV, NFV196M46I, I54V, L90M L10I, I13V, I15V, K20I, E35D, M36I, N37D, R41K, R57K, Q61H, I66F, H69K, V82I, L89M, Q92KG
  TK2013b IDV, SQV, RTV, NFV, LPV, APV225M46I, I47V, I54V, L90M L10I, I13V, I15V, K20I, E35D, M36I, N37D, R41K, R57K, Q61H, I66F, H69K, V82I, L89IM, Q92KG
 PL1003066215 SQV, IDV275I54V, V82A, L90MF53LL10I, I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63P, C67CF, H69K, A71V, L89IG
 PL1087759219 IDV, SQV194I54V, V82T, L90M L10LI, I13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, L63LP, H69K, A71V, T74S, L89I, T91TN, T96TNG
 PL1481477297 NFV221M46I, L90M I13V, K14R, K20I, E35D, M36V, R41K, Q61H, I62V, L63P, C67E, H69K, A71I, T74S, V82I, L89I, I93MG
  78800 NFV228M46I, L90M I13V, K14R, K20I, E35D, M36V, R41K, Q61H, I62V, L63P, C67E, H69K, A71I, T74S, V82I, R87E, L89I, I93MG
 PL2824476856 IDV91I54V, L90ML33LII13V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89IG
 PL3237374841 IDV, NFV, RTV148I54V, L90ML89VI13V, K14R, I15V, K20T, E35D, M36I, R41K, Q61E, H69K, K70R, V82IG
 PL3263599822 IDV, SQV, RTV216I54V, L90MF53LI13V, K14R, L19I, K20I, E35D, M36I, R41K, L63LP, H69K, A71V, V82I, L89IG
 PL3965167522 NFV151I54V, L90M I13V, K14R, K20I, E35N, M36I, R41K, K45KR, I62IV, H69K, A71AV, T74S, V82VI, L89IG
 PL4050977525 NFV171I54IL, L90M I13V, K14R, K20T, E35D, M36I, R41K, I62IV, H69K, A71T, V82I, L89IG
 PL405467728 SQV, NFV, IDV255M46ML, I54V, L90M I13V, K14R, I15V, K20T, E35DN, M36I, R41K, D60DE, I62IV, H69K, T74S, V82I, L89IG
  105535 SQV, NFV, IDV267I54V, L90M I13V, K14KR, I15V, K20T, E35D, M36I, R41K, I62V, H69K, T74S, V82I, L89IG
 PL4092397544 SQV, NFV, LPV129L90M I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 PL4208372851 NFV, RTV, IDV214M46I, I54V, V82F, L90M L10I, I13V, K14R, I15IV, K20I, E35D, M36V, N37ND, R41K, R57RK, D60DE, L63LP, H69K, A71AV, L89IG
 PL4307775315 NFV224M46L, I54V, L90M I13V, K14R, L19I, K20I, E35N, M36I, R41K, K55KR, R57RK, H69K, V82I, L89MG
 PL4315675500 SQV, NFV281L90M I13V, K14R, I15IV, K20T, E35DN, M36I, R41K, I62IV, H69K, A71T, T74S, V82I, L89IG
 PL4432678321 IDV263M46I, I54V, L90M I13V, K14KR, K20I, E35D, M36I, R41K, H69K, V82I, L89M, I93MG
 PL4469979216 IDV256M46I, V82T, I84IV, L90ML89VI13AV, K14KR, I15V, K20I, E35D, M36I, N37ND, R41RK, L63P, H69K, A71ATG
 PL4492479756 Unknown, LPV>82I54V, L90MF53LI13V, I15IV, K20I, E35D, M36I, N37ND, R41K, I62V, L63P, H69K, K70KR, A71V, T74S, V82I, L89I, Q92QRG
 PL4504180062 NFV130L90M I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 PL45291105157 NFV64L90ML23II13V, K20I, E35G, M36I, R41K, H69K, T74S, V82I, L89MG
 PL4812187876 IDV, NFV234L90M L10I, I13V, K14R, L19I, K20IV, E35D, M36I, N37NT, R41K, I62V, I66F, H69K, A71V, V82I, Q92KG
 PL5048894311 RTV, IDV84I54V, V82T, I84V, L90M I13V, K14R, I15V, K20I, E35D, M36I, R41K, C67F, H69K, A71V, L89IG
 PL5246199339 IDV178I54V, V82T, L90M L10LI, I13V, K14R, I15V, K20I, E35D, M36I, R41K, I62IV, L63LP, C67W, H69K, A71V, L89IG
 PL53397101698 IDV114M46I, L90M T12TA, I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89TG
 PL53558102179 NFV212L90M I13V, K20I, E35D, M36I, R41RK, I64IV, H69K, V82I, L89IMG
 PL550897431 IDV126L90M T12A, I13V, K14R, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89IG
 PL865105515 SQV486I54V, L90MF53LL10I, I13V, K14KR, K20I, E35D, M36I, N37D, R41K, L63A, H69K, A71V, T74S, V82I, L89IG
 PL1197773201 NFV36L90M I13V, K14R, I15IV, K20T, E35D, M36I, R41K, I62V, H69K, A71T, T74S, V82I, L89IG
Weber (2005)M64940M64940AY677452IDV, NFV, LPV293G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, A71VG
  M64940AY714453IDV, NFV195G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, K70KR, A71VG
Baxter (2006)48-12171217-30701DQ877755PINAI54V, V82A, L90MV11I, F53LL10V, T12K, I13V, K14R, G16E, K20I, L33L_L, E35D, M36I, R41K, I62V, H69K, A71V, L89IG
 48-12511251-30602DQ877776PINAM46I, I54V, V82T, I84V, L90ML89VL10I, I13V, K20I, E35D, M36I, N37D, R41K, K55N, I62V, L63P, C67F, H69K, A71V, T74SG
 48-22122212-30624DQ877865PINAI54V, V82VFI, L90ML23LI, F53FL, L89MVL10LI, I13AV, K14R, K20I, E35G, M36I, R41K, D60E, L63P, H69KR, A71V, T74S, I93LG
 48-33183318-30924DQ878218PINAG48V, I54V, V82M, L90MK43T, T74PL10V, T12TK, I13V, K20I, E35D, M36IV, N37D, R41K, Q61QH, I62V, C67E, H69K, L89MG
Knops (2010)Pat02Pat02GU991863NFV L90M I13V, K20V, E35D, M36I, N37D, G40GE, R41K, H69K, T74S, V82I, L89IG
 Pat05Pat05GU991866NFV L90M I13V, I15IV, L19LI, K20AITV, E35DG, M36I, N37ND, R41K, I62IV, L63LP, H69K, K70KR, A71T, T74TS, V82I, L89IG
 Pat06Pat06GU991867NFV L90ML89VI13V, I15V, K20T, E35D, M36I, N37DE, R41K, R57K, I62V, H69K, A71AT, T74S, V82IG
 Pat08Pat08GU991869NFV, IDV, LPV M46I, I54A, V82M, L90MK43TT4A, L10I, I13V, I15V, L19P, K20I, E35S, M36I, N37E, R41K, V56A, R57K, L63P, H69K, A71V, T74S, V77I, L89I, Q92KG
 Pat14Pat14GU991875SQV, LPV M46L, G48V, I54V, V82S, L90MK43TL10I, T12K, I13V, I15V, K20I, E35N, M36I, N37D, R41K, Q61HN, L63C, C67W, H69K, T74S, L89IG
 Pat17Pat17GU991878SQV, LPV M46I, I54V, V82A, L90ML33I, L89VL10V, I13A, K20V, A22V, E35D, M36I, N37E, R41K, R57K, I62V, L63LP, H69K, K70R, A71T, T74SG
Kouri (2012)CU1326-09CU1326-09JQ585292PINAI54V, V82T, L90ML33F, F53FLL10V, I13V, K20V, E35N, M36I, N37D, R41K, K45V, K55N, L63P, H69K, T74S, L89MG
 CU1566-10CU1566-10JQ585436PINAV32I, M46L, I47A, L90M I13AV, K14R, I15V, K20I, E35D, M36I, N37ND, R41K, L63P, H69K, V82I, L89IG
 CU2143-09CU2143-09JQ585346PINAM46I, V82T, I84V, L90ML33I, L89VL10I, I13A, K20I, M36I, R41K, L63LP, C67E, H69K, A71VG
Rawizza (2013)LL6229LL6229KF241481LPV L90MF53FILI13V, K14R, K20I, E35D, M36I, N37NK, R41K, L63P, C67E, H69K, V82I, L89MG
Grossman (2014)10431043 NFV, LPV52M46I, I54V, V82F, L90M I13V, K14R, K20I, E35H, M36I, N37D, R41K, K55R, L63P, C67E, H69K, A71I, L89I, I93MG