<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L89V
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 25
Isolates 28
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cuevas (2002)CU75CU75AF425456SQV L90MF53L, L89VL10V, I13V, K20I, M36I, R41K, Q61E, H69K, K70R, A71V, T74SG
Vergne (2003)VL01SN63HPD01SN63AJ583750IDV M46I, V82TL89VL10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69KG
Montes (2004)MB_patPAL99_PAL710AJ577967SQV, RTV, NFV130D30N, M46L, L90ML33I, N88D, L89VI13V, K20I, M36I, L63P, C67S, H69K, A71VG
  01_PAL708AJ577968SQV, RTV, NFV251D30N, M46L, I54V, L90ML33I, N88D, L89VI13V, K20I, M36I, N37K, L63P, C67S, H69K, A71VG
Non-B Workgroup (2005)PL87158009AY900725IDV, RTV108I54V, V82AL89VI13V, K14R, I15IV, K20I, E35D, M36I, R41K, M46X, L63LP, H69K, A71V, I93IMG
 PL2647363176AY901007SQV, NFV, IDV, RTV, LPV I54V, V82F, L90ML89VL10I, I13V, K14R, K20I, E35N, M36I, N37ND, R41K, L63P, H69K, A71V, Q92QKG
  89488 SQV, NFV, IDV, RTV, LPV, UnknownNAM46I, I50V, I54V, V82F, L90ML89VL10I, I13A, K14R, K20IT, A22AV, E35N, M36I, N37D, R41K, L63P, I66V, C67CR, H69K, K70KT, A71V, I85IV, Q92KG
 PL3126062984AY901012IDV208M46I, I54V, V82SL89VL10LI, I13V, I15V, L19LP, K20I, E35D, M36I, N37ND, R41K, I62IV, L63LP, H69K, K70KR, A71VG
 PL1945463189AY901014Unknown, LPV>22M46L, G48GV, I54V, L90ML89VT4TS, L10LV, I13V, K14R, K20I, M36I, N37D, R41EK, I62V, H69K, A71V, T74S, V82XG
 PL3031563371AY901022IDV M46I, I54V, V82T, I84VL89VL10I, I13A, K14R, K20I, E35D, M36I, N37ND, R41K, L63LP, I66F, H69K, A71V, I85IMG
 PL881364115AY901027SQV, NFV204L90MF53L, L89VI13V, K14KR, K20I, E35D, M36I, R41K, L63P, H69K, A71V, V82IG
 PL3835164549AY901030NFV L90ML89VI13V, K14R, K20I, E35DG, M36I, R41K, H69K, A71T, V82IG
 PL888465233AY901039SQV, IDV, LPV M46I, I54V, L76V, L90MF53L, L89VL10I, I13A, K14R, I15IV, K20I, E35D, M36I, R41K, Q61QH, L63P, H69K, A71IT, V82X, T91TSG
 PL1584967492 IDV I54VL89VI13V, K14KR, K20I, E35D, M36I, R41K, L63P, H69K, A71TG
 PL1168468720AY901063IDV I54V, V82T, I84V, L90LML33LI, L89VL10I, I13A, K14KR, K20I, E35D, M36I, R41K, I66F, H69K, A71VG
 PL2133384771 IDV78 L89VI13V, K14R, K20I, E35D, M36I, R41K, L63LP, H69K, A71TG
 PL30594104269 NFV288M46L, I54VL89VT12TI, I13A, K14R, L19P, K20I, E35D, M36I, N37D, R41K, H69K, V82IG
 PL3237374841 IDV, NFV, RTV148I54V, L90ML89VI13V, K14R, I15V, K20T, E35D, M36I, R41K, Q61E, H69K, K70R, V82IG
 PL4469979216 IDV256M46I, V82T, I84IV, L90ML89VI13AV, K14KR, I15V, K20I, E35D, M36I, N37ND, R41RK, L63P, H69K, A71ATG
Weber (2005)M64940M64940AY677452IDV, NFV, LPV293G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, A71VG
  M64940AY714453IDV, NFV195G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, K70KR, A71VG
Baxter (2006)48-12511251-30602DQ877776PINAM46I, I54V, V82T, I84V, L90ML89VL10I, I13V, K20I, E35D, M36I, N37D, R41K, K55N, I62V, L63P, C67F, H69K, A71V, T74SG
 48-12731273-30904DQ877793PINAM46I, I47V, I54V, V82T, I84VK43T, F53L, L89VL10I, I13A, K14R, K20V, A22V, M36I, N37D, R41K, L63P, I66V, H69K, A71V, T74S, T91TCSG
Knops (2010)Pat06Pat06GU991867NFV L90ML89VI13V, I15V, K20T, E35D, M36I, N37DE, R41K, R57K, I62V, H69K, A71AT, T74S, V82IG
 Pat11Pat11GU991872IDV D30N, I54VL33I, N88D, L89VI13V, L19P, K20I, E35N, M36I, N37D, R41K, K43R, K45Q, H69K, T74S, V82IG
 Pat17Pat17GU991878SQV, LPV M46I, I54V, V82A, L90ML33I, L89VL10V, I13A, K20V, A22V, E35D, M36I, N37E, R41K, R57K, I62V, L63LP, H69K, K70R, A71T, T74SG
El Annaz (2012)59445944.PRJN185255IDV52I54V, V82AL89VI13V, L19I, K20I, E35D, M36I, N37E, L63LP, I64M, H69K, A71V, I72IVG
 1518315183.PRJN185273IDV52I54V, V82A, L90LML89VL10I, I13V, L19I, K20I, E35D, M36I, N37E, L63P, I64M, H69K, A71VG