<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation I84V
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 22
Isolates 22
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cornelissen (2000)MC97GH22MC97GH22AF212291PINAI84V, L90ML89VQ2*, I3L, T4P, L10I, I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69K, A71VG
Non-B Workgroup (2005)PL887561905AY900995IDV M46I, I54V, V82T, I84VQ58EL10I, I13V, K20I, E35D, M36I, R41K, L63P, I66F, H69K, A71AV, T74K, L89MG
 PL2430163125AY901013NFV, RTV, IDV173I54V, I84V, L90M I13V, K14R, K20I, E35D, M36I, R41K, I62IV, L63P, H69K, A71V, T74S, L89IG
 PL3031563371AY901022IDV M46I, I54V, V82T, I84VL89VL10I, I13A, K14R, K20I, E35D, M36I, N37ND, R41K, L63LP, I66F, H69K, A71V, I85IMG
 PL3814564117AY901026SQV, IDV238M46I, I54V, V82T, I84V L10I, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63P, I66F, H69K, K70R, L89MG
 PL1168468720AY901063IDV I54V, V82T, I84V, L90LML33LI, L89VL10I, I13A, K14KR, K20I, E35D, M36I, R41K, I66F, H69K, A71VG
 PL40388105421 IDV190M46MI, I54V, V82T, I84VL89MVL10I, I13V, K14R, I15V, K20I, E35D, M36I, R41K, Q61QH, I62IV, L63LAPV, I66FL, H69K, A71AV, T74TSG
 PL5048894311 RTV, IDV84I54V, V82T, I84V, L90M I13V, K14R, I15V, K20I, E35D, M36I, R41K, C67F, H69K, A71V, L89IG
Weber (2005)M62717M62717AY677383IDV, SQV, RTV, LPV142I54V, I84V, L90M I13AV, K14R, I15IV, K20IV, L24L*, E35D, M36I, N37D, R41K, K45V, L63LP, I64IV, H69K, V82I, L89I, Q92QKG
Baxter (2006)48-12511251-30602DQ877776PINAM46I, I54V, V82T, I84V, L90ML89VL10I, I13V, K20I, E35D, M36I, N37D, R41K, K55N, I62V, L63P, C67F, H69K, A71V, T74SG
 48-12731273-30904DQ877793PINAM46I, I47V, I54V, V82T, I84VK43T, F53L, L89VL10I, I13A, K14R, K20V, A22V, M36I, N37D, R41K, L63P, I66V, H69K, A71V, T74S, T91TCS, F99LG
 48-22272227-30430DQ877869PINAI54V, I84V, L90M L10LI, I13AV, K14R, K20IV, A22AV, E35D, M36I, N37D, R41K, K45V, L63LP, I64IV, I66IV, H69K, A71AT, V82I, L89I, Q92KG
 48-26212621-30820DQ877909PINAM46I, I54V, I84V, L90MN88DI13A, K14R, K20I, M36I, R41K, K45R, L63P, I66L, C67Y, H69K, A71I, L89T, T91SG
 48-31863186-30506DQ878094PINAM46L, I54V, V82A, I84VV11I, L24I, L89IVL10I, I13A, K14R, K20I, A22V, E35D, M36I, R41K, I62V, L63P, C67Y, H69K, A71V, T74S, Q92KG
 48-32833283-30916DQ878190PINAM46I, I54M, L76V, I84VG73A, L89VL10I, I13A, K14KR, L19LI, K20I, L33V, M36I, R41K, K55R, R57RK, D60E, L63P, I66F, H69KG
 48-42174217-30915DQ878451PINAM46L, I54V, I84V, L90ML33F, K43T, N88GL10I, I13V, K14R, K20R, E21Q, E35D, M36I, N37D, Q61N, I62V, L63Q, H69K, A71L, T74S, Q92R, I93MG
 48-80768076-30925DQ879086PINAM46I, I54V, L76V, I84VQ58EL10I, I13V, K14R, I15V, K20I, E35N, M36I, N37D, R57RK, D60Q, L63P, H69K, V82I, L89MG
Kouri (2012)CU1023-09CU1023-09JQ585273PINAM46I, I54V, V82T, I84VL89VL10I, I13A, K14R, K20IV, M36I, N37D, R41K, K55R, R57RG, I66F, H69K, G73E, T74S, T80VG
 CU2143-09CU2143-09JQ585346PINAM46I, V82T, I84V, L90ML33I, L89VL10I, I13A, K20I, M36I, R41K, L63LP, C67E, H69K, A71VG
 CU1288-10CU1288-10JQ585421PINAM46I, I54L, I84VV11I, L33F, Q58EL10I, I13V, K14R, I15V, G16E, L19P, K20V, E35N, M36I, N37D, K55R, R57RK, Q61H, L63S, H69K, K70R, I72IM, I85V, L89MG
 CU330-10CU330-10JQ585385PINAM46I, I47V, G48M, I54V, V82T, I84VL33I, L89VL10I, I13A, K20V, A22V, E35HN, M36I, R41K, K43I, I62IV, I66F, G68D, H69K, A71V, T91SG
Rawizza (2013)PJ6749PJ6749KF241460LPV M46L, G48Q, I54V, L76V, I84VF53LL10V, I13A, K14R, I15V, K20I, E35H, M36I, R41K, K55R, R57K, Q61HN, I64V, C67E, H69K, T74S, L89I, T91AG