<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation V77I
Rx PI-naive
IncludeMixtures No
References 31
Patients 54
Isolates 55
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cuevas (2002)CU56CU56AF425437None   I13V, K14R, K20I, E35D, M36I, R41K, I64L, C67E, H69K, K70N, V77I, V82I, L89MG
Huang (2003)HH8793HH8793AF447856None   I13V, K20I, E35D, M36I, N37K, R41K, C67S, H69K, V77I, V82I, L89MG
Holguin (2005)64645-0202_64645-2AY248315None   I13V, K20I, E35Q, M36L, R41K, R57K, C67E, H69K, V77I, V82I, L89M, I93MG
Non-B Workgroup (2005)PL3681464068 None   I13V, K14R, K20I, E35D, M36I, R41K, L63LP, H69K, V77I, V82I, L89MG
 PL54063103417 None   I13V, K14R, Q18QR, K20I, E35D, M36I, R41K, H69K, V77I, V82I, L89MG
Zeh (2005)99NG107799NG1077AY103365None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89M, I93LG
 99NG125399NG1253AY103371None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89M, I93LG
 99NG66399NG663AY103385None   I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89M, I93LG
 99NG88199NG881AY103397None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V77I, V82I, L89M, I93LG
Ojesina (2006)AIO_DDJ172AIO_DDJ172DQ273949None   I13V, K20I, M36I, R41K, C67S, H69R, V77I, V82I, L89MG
 AIO_DDJ278AIO_DDJ278DQ273965None   I13V, K20I, E35D, M36I, R41K, C67S, H69R, V77I, L89MG
Vergne (2006)LV_03BF-ORAV29603BF-296AM181796None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V77I, V82I, L89MG
Vessiere (2006)AV_M3596NAV_M3596NDQ297257None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V77I, V82I, L89MG
Palma (2007)Pt139115486 None   I13V, K14R, I15V, K20I, E35D, M36I, P39S, R41K, H69K, V77I, V82I, L89MG
 Pt149121077 None   L10I, I13V, K14R, K20I, E34Q, E35D, M36I, P39PS, R41K, C67E, H69K, I72IV, V77I, L89MG
 Pt187132086 None   I3L, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V77I, V82I, L89MG
Sylla (2008)D647D647_C1DQ991664None   I13V, I15V, G16A, K20I, E35D, M36I, R41K, H69K, V77I, L89MG
  D647_C2DQ991665None   I13V, I15V, G16A, K20I, E35D, M36I, R41K, H69K, V77I, L89MG
Hawkins (2009)P904ZZP904FJ931178None   I13V, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89MG
 Q217ZZQ217FJ931215None   I13V, K14R, I15V, L19LI, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89MG
 Q227ZZQ227FJ931220None   I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89MG
 Q794ZZQ794FJ931248None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89MG
 R367ZZR367FJ931405None   I13V, K20I, E35D, M36I, R41K, R57K, L63Q, C67S, H69R, V77I, V82I, L89MG
Tebit (2009)TR230TR230FJ577343None  V11II13V, K20I, E35D, M36I, R41K, L63P, H69K, V77I, L89MG
Vercauteren (2009)pt2173210211584GQ398851None   I13V, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V77I, V82I, L89MG
 pt6679014482503GQ400357None   I13V, K20I, E35D, M36I, N37D, R41K, H69K, V77I, V82I, L89MG
Yaotse (2009)HT04306TG.HT043FM955684None   T12R, I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, K70KR, V77I, L89MG
Yebra (2009)SP63-378672SP63-378672EU362924None   I13V, G17E, L19I, K20I, E35D, M36I, R41K, L63P, C67S, H69K, V77I, L89MG
Charpentier (2011)147CP001498 None   I13V, L19IV, K20I, E35D, M36I, R41K, L63A, C67S, H69K, K70R, V77I, V82I, L89MG
Caron (2012)Gab082026Gab082026JN704999None   L10I, I13V, K14R, K20I, E34Q, M36I, R41K, C67S, H69K, K70R, V77I, L89MG
Chamberland (2012)D312TD312THQ267613None   I13V, K14R, K20I, L33V, E35D, M36I, R41K, L63P, H69K, V77IG
 D372TD372THQ267658None   I13V, K14R, I15V, K20I, E35H, M36I, N37D, R41K, R57K, L63LFPS, C67E, H69K, V77I, V82I, L89MG
Karlsson (2012)SE_229SE_229JQ698829None   T4A, T12TA, I13V, K14KR, G16E, K20I, E35D, M36I, R41K, H69K, K70R, V77I, L89MG
Sagoe (2012)KAF130KAF130HQ170623None   L10I, I13V, G17E, K20I, E35N, M36I, R41K, L63P, H69N, V77I, L89MG
Somda (2012)44-170-2044-170-20HG529936None   I13V, K20I, E35D, M36I, K43R, L63P, C67E, H69K, V77I, V82I, L89IG
Frentz (2013)EHR-39409EHR-39409JX300208None   L10I, I13V, K14KR, K20I, E35N, M36I, R41K, I62IV, L63T, C67E, H69Q, I72T, V77I, V82I, L89MG
Nii-Trebi (2013)KF66KF66AB751478None   I13V, K20I, E35G, M36I, N37S, P39Q, R41K, I64L, H69K, K70E, V77I, L89MG
Theys (2013)144664144664 None   T12TA, I13V, K14R, I15V, K20I, E35D, M36I, P39S, R41K, H69K, V77I, V82I, L89MG
Thiam (2013)680-HALD680-HALDJN673692None   I13V, K20I, E35D, M36I, N37D, R41K, H69K, T74S, V77I, L89MG
Aghokeng (2014)TG-3-221TG-3-221KC350292None  M46MRI13V, K20I, E35N, M36I, N37D, R41K, C67CW, H69K, V77I, L89MG
 TG-5-668TG-5-668KC350305None   I13V, K14R, G16E, K20I, E35N, M36I, R41K, H69K, K70R, V77I, L89MG
 TG-2-560TG-2-560KC350108None   L10V, I13V, K14R, K20I, M36K, N37D, R57K, C67S, H69K, K70R, V77I, L89MG
 TG-1-050TG-1-050KC350114None   I13V, K20I, E35D, M36I, N37D, R41K, R57K, D60E, L63P, C67S, H69K, V77I, V82I, L89MG
Bruzzone (2015)HM0470FHM0470FEU914172None   L10LV, I13AV, K14I, L19M, K20I, E34HQ, M36I, N37D, P39PQR, C67S, H69K, V77I, V82I, L89IMG
Carvalho (2015)165165KM205913None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67Y, H69K, V77I, V82I, L89MG
 153153KM205925None   I13V, K14KR, K20I, E35D, M36I, R41K, H69K, V77I, V82VI, L89MG
Dauwe (2015)G_01_18G_01_18KT863853None   I13V, K20I, E35D, M36I, R41K, H69K, V77I, V82I, L89MG
 i6_05082i6_05082KT863884None   T12E, I13V, K20I, L33V, E35G, M36I, R41K, K45R, L63R, I64L, H69K, K70E, V77I, L89MG
 i6_08070i6_08070KT863885None   T12E, I13V, K20I, L33V, E35G, M36I, L38I, R41K, K45R, L63R, I64L, H69K, K70E, V77I, R87RQ, L89MG
 14_01_1514_01_15KT863543None   I13V, L19I, K20I, E35D, M36I, R41K, H69K, V77I, V82I, L89MG
Diallo (2015)1-1-0881-1-088JX084028None   G16GE, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, I72V, V77I, V82I, L89MG
 2-1-0642-1-064JX084179None   I15IV, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77I, V82I, L89MG
 2-1-0102-1-010JX084131None   I15IV, K20I, E35DN, M36I, N37NS, R41K, C67E, H69K, V77I, V82I, L89MG
Abdellaziz (2016)1446614466KT339057None   I13V, I15V, G16E, K20I, E35G, M36I, P39S, L63T, I64IM, E65ED, H69K, V77I, L89MG
 1549715497KT339034None   I13V, I15L, K20I, E34Q, E35D, M36I, N37D, R41K, R57K, I64M, H69K, V77I, L89MG