<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation T74S
Rx PI-naive
IncludeMixtures No
References 11
Patients 13
Isolates 13
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Holguin (2002)AH_G4383AH_G4383AF354023None   I13V, K20I, E35D, M36I, R41K, H69K, T74S, L89MG
Konings (2004)KF_Pat3900CM4857AY359721None   L10I, I13V, K20I, E35D, M36I, R41K, D60E, L63V, C67S, H69R, T74S, L89MG
 KF_Pat4000CM1678AY359722None   L10I, I13V, K20I, E35D, M36I, R41K, D60E, L63V, C67S, H69R, T74S, L89MG
Non-B Workgroup (2005)PL3201464894AY901042None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, I72IV, T74S, L89I, I93LG
Palma (2007)Pt148120500 None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63T, C67S, H69K, T74S, V82I, L89M, I93LG
Knops (2010)Pat09Pat09GU991870None  V32VAI13V, I15V, K20V, E35D, M36I, R41K, R57K, H69K, T74S, V82I, L89MG
Hamers (2011)300441CP076300441HM119863None   I3V, L10I, G16A, M36I, N37D, R41K, K43R, D60N, Q61D, C67E, H69K, T74S, L89M, I93LG
Karlsson (2012)SE_125SE_125JQ698754None   I13V, K14R, K20I, E35G, M36I, P39S, R41K, H69K, T74S, V82I, L89M, I93LG
Machado (2012)CUPL1150CUPL1150JX194229None   I13V, K14R, K20I, M36I, R41K, H69K, T74S, V82I, L89M, I93LG
Ugbena (2012)1-1-0161-1-016JX084001None   K20I, E35Q, M36I, N37D, R41K, R57K, I62V, L63S, C67E, H69K, T74S, V82I, L89MG
Pircher (2013)A1033A1033JX110279None   I13V, K20I, M36I, R41K, H69K, K70R, T74S, V75I, L89MG
Carvalho (2015)261261KM206091None   I13V, K14KR, K20I, E35D, M36I, N37ND, R41K, K43KR, R57K, H69K, T74S, L89MG
 288288KM206118None   I13V, K14KR, K20I, E35D, M36I, R41K, L63LP, C67E, H69R, T74S, V77VI, V82I, L89M, I93LG