<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation T74S
Rx PI-naive
IncludeMixtures No
References 14
Patients 17
Isolates 17
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)PL3201464894AY901042None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, I72IV, T74S, L89I, I93LG
 PL2552680344 None   I13V, K14KR, K20M, E35D, M36I, R41K, L63P, H69K, K70KR, T74S, L89MG
Palma (2007)Pt148120500 None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63T, C67S, H69K, T74S, V82I, L89M, I93LG
Derache (2008)BKO-943BKO-943EU330678None   I13V, K20I, E35D, M36I, R41K, K43R, H69K, I72M, T74S, L89MG
Hawkins (2009)P613ZZP613FJ931127None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, R57K, I64L, H69K, T74S, L89MG
Knops (2010)Pat09Pat09GU991870None  V32VAI13V, I15V, K20V, E35D, M36I, R41K, R57K, H69K, T74S, V82I, L89MG
Avi (2011)081u081uGQ926644None   L10I, I13V, K14R, G17E, K20I, E35D, M36I, R41K, L63P, H69K, T74S, L89M, F99LG
Karlsson (2012)SE_125SE_125JQ698754None   I13V, K14R, K20I, E35G, M36I, P39S, R41K, H69K, T74S, V82I, L89M, I93LG
Machado (2012)CUPL1150CUPL1150JX194229None   I13V, K14R, K20I, M36I, R41K, H69K, T74S, V82I, L89M, I93LG
Avi (2013)116116JX431699None   I13V, K14R, G17E, K20L, E35D, M36I, R41K, L63Q, H69K, K70R, T74S, L89MG
Thiam (2013)680-HALD680-HALDJN673692None   I13V, K20I, E35D, M36I, N37D, R41K, H69K, T74S, V77I, L89MG
Carvalho (2015)261261KM206091None   I13V, K14KR, K20I, E35D, M36I, N37ND, R41K, K43KR, R57K, H69K, T74S, L89MG
 288288KM206118None   I13V, K14KR, K20I, E35D, M36I, R41K, L63LP, C67E, H69R, T74S, V77VI, V82I, L89M, I93LG
Diallo (2015)1-1-1841-1-184JX084121None   I15V, K20I, E35Q, M36I, R41K, R57K, Q61E, C67E, H69K, T74S, L89MG
 1-1-0161-1-016JX084001None   K20I, E35Q, M36I, N37D, R41K, R57K, I62V, L63S, C67E, H69K, T74S, V82I, L89MG
Kouri (2015)AIDS-RP47AIDS-RP47KP688124None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, T74S, L89MG
Heipertz (2016)NG060409NG060409KX389648None   P1PS, T12A, I13V, K14R, I15V, K20I, E35K, M36I, N37E, R41K, I62V, I64L, C67E, H69K, T74S, V82I, L89MG