<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L63T
Rx PI-naive
IncludeMixtures No
References 25
Patients 32
Isolates 32
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Arien (2005)VI2641VI2641DQ177226None   L10I, I13V, I15V, L19P, K20I, M36I, R41K, L63T, C67S, V82I, L89MG
Holguin (2005)50320-0202_50320-2AY248319None   L10I, I13V, K14R, G17E, K20I, E35Q, M36I, R41K, R57K, L63T, C67E, H69K, V82I, L89MG
Punzi (2005)CAR-70CAR-70AY626960None   L10V, I13V, K14R, I15V, K20R, E35N, M36V, R41K, L63T, H69K, I72V, L89MG
Niama (2006)CHU56CHU56FM164923None   I13V, K20I, M36I, R41K, L63T, I64L, I72T, V82I, L89MG
Tebit (2006)D004D004DQ682731None   T12E, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63T, I64M, E65D, H69K, K70R, L89MG
Holguin (2007)LP545551LP545551DQ009062None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63T, H69K, L89MG
Palma (2007)Pt148120500 None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63T, C67S, H69K, T74S, V82I, L89M, I93LG
 Pt200134605 None   T12A, I13V, K20I, E35D, M36I, R41K, L63T, H69K, V82I, L89MG
Sanchez Onoro (2007)545551545551 None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63T, H69K, L89MG
Derache (2008)BKO-1038BKO-1038EU330723None   L10I, I13V, K20I, E35N, M36I, R41K, L63T, E65D, C67S, H69K, I72T, V82I, L89MG
Hawkins (2009)Q973ZZQ973FJ931306None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63T, C67E, H69K, V82I, L89MG
 R443ZZR443FJ931454None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63T, C67E, H69K, V82I, L89MG
Yaotse (2009)HT14306TG.HT143FM955735None   I13V, K20I, E35D, M36I, L63T, I64L, C67S, H69K, V82I, L89MG
Dagnra (2011)08TG.E504708TG.E5047FR715281None   I13V, K14R, I15V, K20I, M36I, P39Q, R41K, L63T, I64L, C67S, H69R, I72T, V82I, L89MG
Hamers (2011)CP076303555CP076303555HQ994031None   I13V, G17E, Q18K, K20I, M36I, R41K, L63T, I64M, C67S, H69K, V82I, L89MG
Afonso (2012)ANG43ANG43JN937056None   M36I, R41K, L63T, C67E, H69R, V82I, L89MG
 ANG104ANG104JN937109None   M36I, R41K, I62V, L63T, C67N, H69K, V82I, L89MG
Chamberland (2012)C512SC512SHQ267602None  L89VT12A, I13V, I15V, G16E, K20I, E35D, M36I, R41K, K45R, Q61N, L63T, I64L, E65D, H69K, I72T, G73DG
Serrano (2012)20106934742010693474JQ616900None  V11IL10I, T12Q, I13V, K14KR, I15V, L19P, K20I, E35D, M36I, R41K, L63T, H69K, L89MG
Billong (2013)MR084MR084KF192250None  V11VIL10I, I13V, K14R, K20I, M36I, N37S, R41K, K43KR, R57K, D60E, Q61G, L63T, C67E, H69R, L89MG
Frentz (2013)EHR-39409EHR-39409JX300208None   L10I, I13V, K14KR, K20I, E35N, M36I, R41K, I62IV, L63T, C67E, H69Q, I72T, V77I, V82I, L89MG
Aghokeng (2014)TG-3-344TG-3-344KC350112None   I13V, I15V, K20I, E35D, M36I, R41K, L63T, I64M, C67S, H69K, V82I, L89MG
 TG-3-620TG-3-620KC350111None   I13V, I15V, K20I, E35D, M36I, R41K, L63T, I64M, C67S, H69K, V82I, L89MG
 TG-1-025TG-1-025KC350214None   I13V, I15V, K20I, E35D, M36I, R41K, L63T, I64M, C67S, H69K, V82I, L89MG
Agyingi (2014)LB041LB041KF576479None   K14R, I15V, G16E, K20I, E35Q, M36I, R41K, R57K, L63T, C67E, H69N, I72T, V82I, L89MG
Loubet (2014)LILX011323LILX011323KJ468020None   L10I, I13V, K14R, K20I, M36I, R41K, L63T, I64L, C67S, H69K, V82I, L89MG
Dauwe (2015)NA_01_29NA_01_29KT863914None   I13V, K14R, K20I, E35D, M36V, R41K, L63T, C67E, H69K, V82I, L89MG
 NA_94611NA_94611KT863944None   L10I, I13V, I15V, L19P, K20I, M36I, R41K, L63T, C67S, V82I, L89MG
Hora (2015)DEURF10CM020DEURF10CM020KP109502None   L10I, T12P, I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57K, L63T, C67E, H69N, I72T, V82I, L89MG
Abdellaziz (2016)1446614466KT339057None   I13V, I15V, G16E, K20I, E35G, M36I, P39S, L63T, I64IM, E65ED, H69K, V77I, L89MG
 1590915909KT339032None  V11IT12S, I13V, K14E, I15V, G16E, K20I, M36I, R41K, Q61H, L63T, I64M, C67G, H69K, K70R, I72T, L89MG
Onsongo (2016)4646KM376173None   E35D, M36I, R41K, L63T, H69S, K70R, N83S, L89MG