<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L63S
Rx PI-naive
IncludeMixtures No
References 25
Patients 40
Isolates 40
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Holguin (2002)AH_R3620AH_R3620AF354037None   I13V, K14R, K20I, M36I, R41K, L63S, H69K, P79S, T80P, L89MG
 AH_M2444AH_M2444AF247023None   L10S, T12M, I13V, K14R, G17E, K20I, E34K, M36I, Q61N, I62M, L63S, C67E, H69K, V77I, L89MG
Konings (2004)KF_Pat4100CM786AY359723None   I13V, K20I, E35D, M36I, R41K, I62V, L63S, C67S, H69K, V82I, L89MG
Holguin (2005)2597AH_2597AF466721None   T12K, I13V, I15V, K20I, M36I, R41K, L63S, H69K, L89MG
Punzi (2005)CAR-122CAR-122AY626962None   T12K, I13V, I15L, L19I, K20I, M36I, N37D, R41K, I62V, L63S, I64L, C67S, H69K, V82I, L89MG
Zeh (2005)99NG61999NG619AY103383None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, I62V, L63S, C67E, H69K, V82I, L89M, I93LG
 99NG78299NG782AY103392None   I13V, K14R, K20I, E35D, M36I, R41K, R57K, L63S, C67E, H69K, V82I, L89M, I93LG
Marechal (2006)JF_009JF_009DQ443631None   T12DE, I13V, L19I, K20I, E35D, M36I, R57K, L63S, C67S, H69K, V82I, L89MG
 JF_022JF_022DQ443640None   T12E, I13V, L19I, K20I, E35D, M36I, N37D, R57K, Q61E, L63S, I64IM, C67S, H69R, P79PS, V82I, L89MG
Vessiere (2006)AV_M4611NAV_M4611NDQ297271None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, Q61H, L63S, C67E, H69K, V82I, L89M, I93VG
Vidal (2007)U172002BU.U1720AM260319None   T12P, I13V, K14R, G16E, K20I, M36I, K55R, R57K, L63S, I64M, C67S, H69K, V82I, L89MG
Delgado (2008)GH_161GH_161EU178002None   T12K, I13V, L19I, K20I, M36I, R41K, L63S, C67S, H69K, V82I, L89IG
Derache (2008)BKO-1022BKO-1022EU330714None   I13V, K14R, K20I, M36I, R41K, L63S, I64M, C67E, H69K, L89MG
Hawkins (2009)Q207ZZQ207FJ931209None   I13V, K14R, K20I, E35Q, M36I, R41K, K45R, R57K, L63S, I64M, C67E, H69K, I72V, V82I, L89MG
 Q975ZZQ975FJ931318None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, I62V, L63S, C67E, H69R, V82VI, L89MG
 R107ZZR107FJ931358None   V11A, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, L63S, I64M, C67E, H69K, V82I, L89M, T91AG
 R257ZZR257FJ931402None   L10M, I13V, K14R, K20I, E35Q, M36I, R41RK, R57K, I62V, L63S, C67E, H69K, K70R, V82I, L89MG
 R477ZZR477FJ931439None   L10M, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, C67E, H69K, L89MG
Yaotse (2009)HT13906TG.HT139FM955734None   I13V, G17E, K20I, E35D, M36I, R57K, L63S, C67M, H69K, K70R, V82I, L89MG
Hattori (2010)C07-2069006C07-2069006AB867996None   T12A, I13V, K14R, K20I, E35D, M36I, R41K, L63S, H69K, K70R, V82I, L89MG
Yang (2010)20106934352010693435JQ616877None   I13V, K20I, E35D, M36I, R41K, L63S, I64M, C67S, H69K, I72V, V82I, L89MG
Hamers (2011)CP076302258CP076302258HQ993824None   I13V, K14R, K20I, M36I, N37S, R41K, L63S, I64L, H69K, K70R, I72T, L89MG
 CP076303498CP076303498HQ993986None   I13V, K20I, M36I, R57K, L63S, C67S, H69K, V82I, L89MG
 CP076305216CP076305216HQ994149None   T12K, I13V, I15V, L19I, K20I, E35Q, M36I, R41K, R57K, L63S, I64L, C67E, H69K, K70KR, V82I, L89IMG
Ndembi (2011)NTCPS705NTCPS705HQ702665None   I13V, E35D, M36I, R41K, L63S, I64M, C67S, H69K, L89MG
Afonso (2012)ANG20ANG20JN937035None   E35D, M36I, R41K, L63S, I64L, C67*, H69K, V82I, L89MG
 ANG60ANG60JN937072None   M36I, R41K, L63S, I64L, C67E, H69K, V82I, L89M, Q92HG
Ajoge (2012)H24HP24HM854111None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, C67E, H69K, V82I, L89MG
Chamberland (2012)C467SC467SHQ267582None   I13V, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, I64M, C67E, H69K, V82I, L89MG
De Gascun (2012)IRL18404IRL18404JN622317None   L10LM, I13V, K14R, K20I, E35Q, M36I, N37E, R41K, R57RK, I62IV, L63S, C67E, H69K, V82I, L89MG
Ugbena (2012)1-1-0201-1-020JX084005None   K20I, E35Q, M36I, N37D, R41K, R57K, L63S, C67E, H69R, V82I, L89MG
 1-1-0011-1-001JX083986None   K20I, E35Q, M36I, N37D, R41K, K43KR, R57K, I62IV, L63S, C67E, H69K, V82I, L89MG
 1-1-0101-1-010JX083995None   I15IV, K20I, E35Q, M36I, N37D, R41K, R57K, Q61DE, L63S, C67E, H69K, V82I, L89MG
 1-1-0161-1-016JX084001None   K20I, E35Q, M36I, N37D, R41K, R57K, I62V, L63S, C67E, H69K, T74S, V82I, L89MG
 1-1-1071-1-107JX084047None   Q18QK, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, I64IM, C67E, H69R, V82I, L89MG
Aghokeng (2013)HJ3348HJ3348JX983037None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, I64M, C67E, H69K, V82I, L89MG
Billong (2013)MR123MR123KF192248None   I13V, K14R, G17E, K20I, E34K, M36I, P39Q, Q61N, I62M, L63S, C67E, H69K, V77I, L89MG
Frentz (2013)EHR-87026EHR-87026JX301013None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K45R, R57K, I62V, L63S, C67E, H69K, V82I, L89M, T91VG
Imade (2013)ZZRJ074ZZRJ074KC755263None   L10I, I13V, K14R, K20I, E35Q, M36I, N37D, R41RK, R57K, L63S, C67E, H69K, V82I, L89MG
 ZZRJ009ZZRJ009KC755241None   I13V, K14R, K20I, E35Q, M36I, N37D, R57K, L63S, C67E, H69K, V82I, L89MG