<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L63S
Rx PI-naive
IncludeMixtures No
References 49
Patients 85
Isolates 85
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Nkengasong (2000)JN_IC105JN_IC105AF216980None   I13V, K14R, K20I, E35D, M36I, R41K, L63S, H69K, I72V, L89MG
Konings (2004)KF_Pat4100CM786AY359723None   I13V, K20I, E35D, M36I, R41K, I62V, L63S, C67S, H69K, V82I, L89MG
Carr (2005)01NGPL49001NGPL490DQ013273None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63S, C67E, H69K, V82I, L89MG
Holguin (2005)2597AH_2597AF466721None   T12K, I13V, I15V, K20I, M36I, R41K, L63S, H69K, L89MG
Non-B Workgroup (2005)PL4293874996 None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, L63S, I64M, H69K, L89MG
 PL739992290 None   L10LI, I13V, K14R, K20I, E35D, M36I, R41K, L63S, I64L, H69K, K70R, L89MG
Punzi (2005)CAR-122CAR-122AY626962None   T12K, I13V, I15L, L19I, K20I, M36I, N37D, R41K, I62V, L63S, I64L, C67S, H69K, V82I, L89MG
Zeh (2005)99NG61999NG619AY103383None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, I62V, L63S, C67E, H69K, V82I, L89M, I93LG
 99NG78299NG782AY103392None   I13V, K14R, K20I, E35D, M36I, R41K, R57K, L63S, C67E, H69K, V82I, L89M, I93LG
Marechal (2006)JF_009JF_009DQ443631None   T12DE, I13V, L19I, K20I, E35D, M36I, R57K, L63S, C67S, H69K, V82I, L89MG
 JF_022JF_022DQ443640None   T12E, I13V, L19I, K20I, E35D, M36I, N37D, R57K, Q61E, L63S, I64IM, C67S, H69R, P79PS, V82I, L89MG
Vessiere (2006)AV_M4611NAV_M4611NDQ297271None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, Q61H, L63S, C67E, H69K, V82I, L89M, I93VG
Vidal (2007)U172002BU.U1720AM260319None   T12P, I13V, K14R, G16E, K20I, M36I, K55R, R57K, L63S, I64M, C67S, H69K, V82I, L89MG
Delgado (2008)GH_119GH_119EU177969None   L10I, I13V, K14R, L19P, K20I, E35ED, M36I, R41K, L63S, H69K, K70R, L89MG
 GH_161GH_161EU178002None   T12K, I13V, L19I, K20I, M36I, R41K, L63S, C67S, H69K, V82I, L89IG
Derache (2008)BKO-979BKO-979EU330697None   I13V, K14R, I15V, G17E, K20I, E35D, M36I, L63S, I64M, H69K, L89MG
 BKO-1022BKO-1022EU330714None   I13V, K14R, K20I, M36I, R41K, L63S, I64M, C67E, H69K, L89MG
Yamaguchi (2008)J11233J11233EU697906None   T12S, I13V, L19I, K20I, M36I, N37S, R41K, L63S, I64M, C67E, H69K, K70R, V82I, L89MG
Aghokeng (2009)SK_0304SK_0304GU191681None   L10V, T12K, I13V, I15IL, G17E, K20I, M36I, R41K, L63S, H69K, L89MG
Ayouba (2009)0.2340.234-BPRGQ351814None   I13V, K14R, K20I, M36I, N37T, R41K, L63S, H69K, K70R, L89MG
Hawkins (2009)Q207ZZQ207FJ931209None   I13V, K14R, K20I, E35Q, M36I, R41K, K45R, R57K, L63S, I64M, C67E, H69K, I72V, V82I, L89MG
 Q975ZZQ975FJ931318None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, I62V, L63S, C67E, H69R, V82VI, L89MG
 R107ZZR107FJ931358None   V11A, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, L63S, I64M, C67E, H69K, V82I, L89M, T91AG
 R257ZZR257FJ931402None   L10M, I13V, K14R, K20I, E35Q, M36I, R41RK, R57K, I62V, L63S, C67E, H69K, K70R, V82I, L89MG
 R477ZZR477FJ931439None   L10M, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, C67E, H69K, L89MG
Tebit (2009)TR239TR239FJ577350None   I13V, K14R, K20I, T31P, E35D, M36I, R41K, L63S, I64M, H69K, L89MG
Vercauteren (2009)pt20251187538504GQ398999None   T12A, I13V, K20I, E35D, M36I, R41K, L63S, H69K, L89MG
 pt15843852420844GQ399440None   I13V, K14R, K20I, E35D, M36I, L63S, I64M, H69K, L89MG
 pt13635047243384GQ399661None   I13AV, K14R, L19LI, K20I, E35ED, M36I, R41K, L63S, I64M, H69K, L89MG
Yaotse (2009)HT13906TG.HT139FM955734None   I13V, G17E, K20I, E35D, M36I, R57K, L63S, C67M, H69K, K70R, V82I, L89MG
Cuevas (2010)ES_P1981-2ES_P1981-2FJ670530None   I13V, K20I, E35D, M36I, R41K, L63S, H69K, V82I, L89MG
Hattori (2010)C07-2069006C07-2069006AB867996None   T12A, I13V, K14R, K20I, E35D, M36I, R41K, L63S, H69K, K70R, V82I, L89MG
de Felipe (2011)SE16PR_SE16JF338631None   I13V, K14R, G16E, K20I, M36I, R41K, L63S, I64L, H69K, K70R, V75I, V82I, L89MG
Hamers (2011)CP076302258CP076302258HQ993824None   I13V, K14R, K20I, M36I, N37S, R41K, L63S, I64L, H69K, K70R, I72T, L89MG
 CP076303498CP076303498HQ993986None   I13V, K20I, M36I, R57K, L63S, C67S, H69K, V82I, L89MG
 CP076305216CP076305216HQ994149None   T12K, I13V, I15V, L19I, K20I, E35Q, M36I, R41K, R57K, L63S, I64L, C67E, H69K, K70KR, V82I, L89IMG
Ndembi (2011)NTCPS705NTCPS705HQ702665None   I13V, E35D, M36I, R41K, L63S, I64M, C67S, H69K, L89MG
Afonso (2012)ANG20ANG20JN937035None   E35D, M36I, R41K, L63S, I64L, C67*, H69K, V82I, L89MG
 ANG60ANG60JN937072None   M36I, R41K, L63S, I64L, C67E, H69K, V82I, L89M, Q92HG
Ajoge (2012)H24HP24HM854111None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, C67E, H69K, V82I, L89MG
Caron (2012)Gab013118Gab013118JN704992None   I13V, K14R, G16E, L19I, K20I, E35D, M36I, R41K, I62V, L63S, I64M, H69K, L89MG
Chamberland (2012)C467SC467SHQ267582None   I13V, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, I64M, C67E, H69K, V82I, L89MG
 D316TD316THQ267616None   I13V, K14R, K20I, A28V, M36I, R41K, L63S, I64L, H69K, L89MG
Charurat (2012)09NG.SC2609NG.SC26JN248586None   I13V, K20I, E35Q, M36I, N37D, R57K, L63S, C67E, H69R, V82I, L89IG
De Gascun (2012)IRL18404IRL18404JN622317None   L10LM, I13V, K14R, K20I, E35Q, M36I, N37E, R41K, R57RK, I62IV, L63S, C67E, H69K, V82I, L89MG
Serrano (2012)20106934352010693435JQ616877None   I13V, K20I, E35D, M36I, R41K, L63S, I64M, C67S, H69K, I72V, V82I, L89MG
Somda (2012)8A-316-238A-316-23HG529942None   L10V, I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63S, I64M, C67HY, H69K, L89MG
 9-2774-229-2774-22HG529965None   T12S, I13V, K14R, K20I, E35D, M36I, R41K, L63S, I64M, H69K, I72T, L89MG
Aghokeng (2013)HJ3348HJ3348JX983037None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, I64M, C67E, H69K, V82I, L89MG
Frentz (2013)EHR-87026EHR-87026JX301013None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K45R, R57K, I62V, L63S, C67E, H69K, V82I, L89M, T91VG
Imade (2013)ZZRJ074ZZRJ074KC755263None   L10I, I13V, K14R, K20I, E35Q, M36I, N37D, R41RK, R57K, L63S, C67E, H69K, V82I, L89MG
 ZZRJ009ZZRJ009KC755241None   I13V, K14R, K20I, E35Q, M36I, N37D, R57K, L63S, C67E, H69K, V82I, L89MG
Kebe (2013)SNA3-196SNA3-196JN193494None   I13V, K14R, I15IV, K20I, E35N, M36I, R41K, L63S, I64M, H69K, L89MG
 SNA3-195SNA3-195HM002541None   I13V, K14R, I15IV, K20I, E35N, M36I, R41K, L63S, I64M, H69K, L89MG
Theys (2013)135653135653 None   I13V, K14R, K20I, E35D, M36I, R41K, L63S, I64M, H69K, K70R, L89MG
 137069137069 None   I13V, K14R, K20I, E35D, M36I, R41K, L63S, I64M, H69K, K70R, L89MG
 9229092290 None   L10LI, I13V, K14R, K20I, E35D, M36I, R41K, L63S, I64L, H69K, K70R, L89MG
Thiam (2013)MH-022MH-022JN673693None   L10I, I13V, G16E, L19P, K20IM, E35D, M36I, R41K, L63S, H69K, K70KR, L89MG
Loubet (2014)LILX011414LILX011414KJ467969None   L10LI, I13V, K14KR, I15V, K20I, E35Q, M36I, R41K, R57K, L63S, C67E, H69K, V82I, L89MG
Niculescu (2014)DU2637bhDU2637bhKJ194808None   T12TA, I13V, K14R, K20I, E35D, M36I, R41K, R57K, I62IV, L63S, I64IM, E65D, V82VI, L89MG
 DU2728bhDU2728bhKJ194734None   I13V, K14R, K20I, E35D, M36I, R41K, R57K, L63S, E65D, L89MG
Carvalho (2015)180180KM205898None   T12AS, I13V, K14R, I15V, K20I, E35D, M36I, N37ND, R41K, L63S, I64M, H69K, V82IG
Dauwe (2015)G_07069G_07069KT863864None   I13V, K14R, I15V, K20I, M36I, R41K, L63S, I64M, C67E, H69K, V82I, L89MG
 G_01035G_01035KT863854None   I13V, K14R, K20I, E35Q, M36I, N37E, R41K, R57K, L63S, C67E, H69K, V82I, L89MG
Diallo (2015)1-1-0201-1-020JX084005None   K20I, E35Q, M36I, N37D, R41K, R57K, L63S, C67E, H69R, V82I, L89MG
 2-1-0802-1-080JX084195None   I15V, K20I, E35ED, M36I, R41K, L63S, I64M, H69K, K70R, L89MG
 1-1-1201-1-120JX084060None   G17GE, K20I, M36I, R41K, L63S, H69K, K70KR, I72T, L89MG
 1-1-0011-1-001JX083986None   K20I, E35Q, M36I, N37D, R41K, K43KR, R57K, I62IV, L63S, C67E, H69K, V82I, L89MG
 1-1-0101-1-010JX083995None   I15IV, K20I, E35Q, M36I, N37D, R41K, R57K, Q61DE, L63S, C67E, H69K, V82I, L89MG
 1-1-0161-1-016JX084001None   K20I, E35Q, M36I, N37D, R41K, R57K, I62V, L63S, C67E, H69K, T74S, V82I, L89MG
 1-1-1811-1-181JX084118None   I15V, G16E, K20I, E35D, M36I, R41K, R57RK, L63S, I64M, G68GE, H69K, L89MG
 1-1-1071-1-107JX084047None   Q18QK, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, I64IM, C67E, H69R, V82I, L89MG
Kouri (2015)AIDS-RP5AIDS-RP5KP688127None   L10I, T12A, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63S, H69K, K70R, V82I, L89MG
 AIDS-RP4AIDS-RP4KP688116None   L10I, T12A, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63S, H69K, K70R, V82I, L89MG
Wilkinson (2015)TV546TV546KJ948662None   T12A, I13V, K14R, I15V, G16E, K20I, E35D, M36L, R41K, L63S, I64L, H69K, K70R, V82I, L89IG
Yao (2015)ZS04ZJ038ZS04ZJ038KJ614012None   I13V, K14R, K20I, M36I, R41K, L63S, I64V, H69K, L89MG
Abdellaziz (2016)18550BM18550BMKT338993None   T12S, I13V, K14R, I15V, K20I, M36I, R41K, L63S, I64L, H69K, L89MG
 1642516425KT339018None   L10V, T12S, I13V, I15V, G16E, K20I, M36I, R41K, Q61HY, L63S, H69K, K70R, L89M, F99FLG
 18923BA18923BAKT338970None   T12S, I13V, K14E, I15V, G16E, L19I, K20I, E35D, M36I, R41K, Q61H, L63S, I64IM, H69K, K70R, L89MG
 18515MO18515MOKT338995None   L10V, T12S, I13V, K14E, I15V, G16E, K20I, M36I, R41K, D60DE, Q61H, L63S, C67Y, H69K, K70R, I72T, L89MG
 1501115011KT339063None  L33IL10I, T12S, I13V, K14R, I15V, K20I, E34Q, M36IT, P39PS, R41K, L63S, H69K, L89MG
Heipertz (2016)NG030498NG030498KX389609None   I13V, K14R, K20I, E35D, M36I, N37D, R41K, L63S, I64L, H69K, L89MG
 NG050158NG050158KX389641None   T12P, I13V, K14R, K20I, E35Q, M36I, N37D, R57K, L63S, C67E, H69K, V82I, L89IG
Lam (2016)2103201521032015KR867797None   I13V, K14R, I15V, G16E, K20I, E35D, M36I, P39S, R41K, L63S, I64M, H69K, K70R, L89MG
 2101200421012004KR867970None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, I62V, L63S, C67E, H69R, V82I, L89MG