<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L63S
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 9
Isolates 11
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M35M35AY010399NFV M46I, L90M L10I, I13V, K14R, G16E, K20I, E35DN, M36I, I62IV, L63S, C67D, H69R, I72T, L89M, I93IMG
Monno (2003)ML_Pat49ML_Pat49 PINA  L10LI, T12TK, I13V, K14R, G17GE, K20I, M36I, R41K, L63S, C67Y, H69K, K70KR, V82I, L89MG
Montes (2004)MB_patDEL01_DEL725AJ577879IDV, RTV21  I13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, L63S, C67E, H69K, V82I, L89MG
  02_DEL707AJ577880IDV, RTV, Unknown>21  I13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, L63S, I64M, C67E, H69K, V82I, L89MG
Sylla (2008)B7127B7127_C1DQ991643IDV   I13V, G17E, K20I, E35N, M36I, R41K, K45R, R57K, L63S, H69K, K70R, I72T, L89MG
  B7127_C2DQ991644IDV   I13V, G17E, K20I, E35N, M36I, R41K, K45R, R57K, L63S, H69K, K70R, I72T, L89MG
Kouri (2012)CU1288-10CU1288-10JQ585421PINAM46I, I54L, I84VV11I, L33F, Q58EL10I, I13V, K14R, I15V, G16E, L19P, K20V, E35N, M36I, N37D, K55R, R57RK, Q61H, L63S, H69K, K70R, I72IM, I85V, L89MG
 CU144-11CU144-11JQ585493PINA  T12A, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63S, H69K, A71T, V82I, L89IG
Grossman (2014)18511851KF135007LPV52  I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63S, C67E, H69K, V82I, L89MG
Abdellaziz (2016)1419814198KT339048PINA  T12S, I13V, K14E, I15V, G16E, K20I, M36I, L63S, H69K, I72M, L89MG
 18032ZF18032ZFKT338949PINA  T12S, I13V, K14E, I15V, G16E, K20I, M36I, R41K, Q61H, I62V, L63S, I64M, H69K, K70R, I72T, L89MG