<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L63P
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 72
Isolates 77
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Vergne (2003)VL01SN63HPD01SN63AJ583750IDV M46I, V82TL89VL10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69KG
Montes (2004)MB_patMAS D01_MASD709AJ577944NFV8  L10I, I13V, K14Q, L19P, K20I, M36I, R41K, L63P, C67Y, H69K, L89MG
 MB_patVIG02_VIG701AJ578178SQV, RTV, IDV252M46I, I54A, V82T L10I, I13V, K14R, K20I, E35N, M36I, N37D, R41K, Q61H, L63P, C67E, H69K, I72V, T74S, L89MG
 MB_patPAL99_PAL710AJ577967SQV, RTV, NFV130D30N, M46L, L90ML33I, N88D, L89VI13V, K20I, M36I, L63P, C67S, H69K, A71VG
  01_PAL708AJ577968SQV, RTV, NFV251D30N, M46L, I54V, L90ML33I, N88D, L89VI13V, K20I, M36I, N37K, L63P, C67S, H69K, A71VG
Non-B Workgroup (2005)PL1708257141AY900715IDV30M46I, V82S I13V, K20I, E35D, M36I, R41K, K45R, L63P, I66F, H69K, K70R, L89MG
 PL3510257431AY900721SQV, NFV, IDV181I54V, L90MF53LI13V, K14KR, K20IV, L33LV, E35D, M36I, R41K, D60E, I62V, L63P, H69K, A71V, T74S, V82I, L89IG
 PL3548458235AY900970NFV M46ML T12A, I13V, K14R, K20T, E35D, M36I, R41K, I62V, L63P, H69K, A71T, T74S, V82I, L89X, I93MG
 PL3516757581AY900979IDV, RTV47I54VL24II13V, K14R, K20I, E35D, M36I, N37K, R41K, L63P, H69K, V82I, L89MG
 PL3655160625AY900985NFV L90M I13V, K14R, G17E, K20I, E35N, M36I, R41K, I62V, L63P, H69K, K70R, A71T, V82I, L89IG
 PL887561905AY900995IDV M46I, I54V, V82T, I84VQ58EL10I, I13V, K20I, E35D, M36I, R41K, L63P, I66F, H69K, A71AV, T74K, L89MG
 PL86262513AY901003IDV, ATV I54V, V82T, L90M I13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, K70R, A71V, T74S, L89IG
 PL2647363176AY901007SQV, NFV, IDV, RTV, LPV I54V, V82F, L90ML89VL10I, I13V, K14R, K20I, E35N, M36I, N37ND, R41K, L63P, H69K, A71V, Q92QKG
  89488 SQV, NFV, IDV, RTV, LPV, UnknownNAM46I, I50V, I54V, V82F, L90ML89VL10I, I13A, K14R, K20IT, A22AV, E35N, M36I, N37D, R41K, L63P, I66V, C67CR, H69K, K70KT, A71V, I85IV, Q92KG
 PL2529062869AY901010SQV L90M I13V, K20I, E35D, M36I, N37NS, R41K, L63P, H69K, K70R, A71AV, V82I, L89MG
 PL2430163125AY901013NFV, RTV, IDV173I54V, I84V, L90M I13V, K14R, K20I, E35D, M36I, R41K, I62IV, L63P, H69K, A71V, T74S, L89IG
 PL3788763577AY901020IDV, RTV   I13V, K14R, G17E, E21K, M36I, R41K, Q58QR, L63P, H69K, K70R, V82I, L89IG
 PL3142163409AY901024IDV, APV, LPV   I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V82I, L89MG
 PL3796663734 IDV   I13V, K14KR, I15V, K20I, E35D, M36I, R41K, L63P, H69K, V82I, L89M, I93LG
 PL3814564117AY901026SQV, IDV238M46I, I54V, V82T, I84V L10I, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63P, I66F, H69K, K70R, L89MG
 PL881364115AY901027SQV, NFV204L90MF53L, L89VI13V, K14KR, K20I, E35D, M36I, R41K, L63P, H69K, A71V, V82IG
 PL3844864783AY901029NFV L90M I13V, K14R, K20I, E35EG, M36I, R41K, D60E, L63P, H69K, T74S, V82I, L89M, I93LG
 PL2053364517AY901032IDV, APV   I13V, K20I, M36I, R41K, L63P, C67S, H69R, I72T, V82I, L89IG
 PL888465233AY901039SQV, IDV, LPV M46I, I54V, L76V, L90MF53L, L89VL10I, I13A, K14R, I15IV, K20I, E35D, M36I, R41K, Q61QH, L63P, H69K, A71IT, V82X, T91TSG
 PL1003066215AY901040SQV, IDV I54V, V82A, L90MF53LL10I, I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63P, C67CF, H69K, A71V, L89IG
 PL1584967492 IDV I54VL89VI13V, K14KR, K20I, E35D, M36I, R41K, L63P, H69K, A71TG
 PL846867575 RTV74I54V, L90MQ58EI13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, V82I, L89MG
 PL1003066215 SQV, IDV275I54V, V82A, L90MF53LL10I, I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63P, C67CF, H69K, A71V, L89IG
 PL1481477297 NFV221M46I, L90M I13V, K14R, K20I, E35D, M36V, R41K, Q61H, I62V, L63P, C67E, H69K, A71I, T74S, V82I, L89I, I93MG
  78800 NFV228M46I, L90M I13V, K14R, K20I, E35D, M36V, R41K, Q61H, I62V, L63P, C67E, H69K, A71I, T74S, V82I, R87E, L89I, I93MG
 PL28120100793 LPV39M46MI, I54V, L76VL24LI, Q58EL10I, I13V, K20I, E35D, M36I, R41K, L63P, H69K, V82I, L89MG
 PL2824476856 IDV91I54V, L90ML33LII13V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89IG
 PL4356276535 SQV, IDV86I54V, V82S I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, T74S, L89IG
 PL4366176757 IDV204  L10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, K70R, V82I, L89M, I93IVG
 PL4469979216 IDV256M46I, V82T, I84IV, L90ML89VI13AV, K14KR, I15V, K20I, E35D, M36I, N37ND, R41RK, L63P, H69K, A71ATG
 PL4492479756 Unknown, LPV>82I54V, L90MF53LI13V, I15IV, K20I, E35D, M36I, N37ND, R41K, I62V, L63P, H69K, K70KR, A71V, T74S, V82I, L89I, Q92QRG
 PL53397101698 IDV114M46I, L90M T12TA, I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89TG
 PL54919106008 IDV, LPV169M46I, I54V, V82SL24IL10LIV, I13V, K14R, K20I, E35DN, M36I, R41K, L63P, H69K, L89MG
 PL717994478 RTV, IDV69  I13V, K14R, G17E, K20I, E35D, M36I, R41K, L63P, H69K, K70R, V82I, L89IG
Weber (2005)M64940M64940AY677452IDV, NFV, LPV293G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, A71VG
  M64940AY714453IDV, NFV195G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, K70KR, A71VG
Baxter (2006)48-12511251-30602DQ877776PINAM46I, I54V, V82T, I84V, L90ML89VL10I, I13V, K20I, E35D, M36I, N37D, R41K, K55N, I62V, L63P, C67F, H69K, A71V, T74SG
 48-12731273-30904DQ877793PINAM46I, I47V, I54V, V82T, I84VK43T, F53L, L89VL10I, I13A, K14R, K20V, A22V, M36I, N37D, R41K, L63P, I66V, H69K, A71V, T74S, T91TCSG
 48-22122212-30624DQ877865PINAI54V, V82VFI, L90ML23LI, F53FL, L89MVL10LI, I13AV, K14R, K20I, E35G, M36I, R41K, D60E, L63P, H69KR, A71V, T74S, I93LG
 48-22252225-30423DQ877867PINAM46I, I47V, I54V, V82AF53LI13V, K14R, K20I, E35D, M36I, N37D, R41K, L63P, H69K, K70R, A71IV, L89I, T91TSG
 48-31863186-30506DQ878094PINAM46L, I54V, V82A, I84VV11I, L24I, L89IVL10I, I13A, K14R, K20I, A22V, E35D, M36I, R41K, I62V, L63P, C67Y, H69K, A71V, T74S, Q92KG
 48-33333333-30929DQ878227PINAM46I, I47V, I54V, I84VL33F, G73SL10V, I13V, I15V, K20T, E35D, M36I, P39S, R41K, Q61D, I62V, L63P, I66F, H69K, T74S, L89TG
 48-43944394-30912DQ878533PINAM46I, I54V, L76V, V82F L10I, I13V, G16GA, K20I, E35D, M36I, L63P, H69K, T74TS, L89MG
 48-80048004-30514DQ879049PINAM46L, I54V, V82A I13V, K20I, A22AV, E35D, M36I, R41K, R57K, L63P, I66F, A71V, T91AG
 48-80768076-30925DQ879086PINAM46I, I54V, L76V, I84VQ58EL10I, I13V, K14R, I15V, K20I, E35N, M36I, N37D, R57RK, D60Q, L63P, H69K, V82I, L89MG
Laurent (2006)CK2-9102CM-91AM279449IDV13  I13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, L89MG
Knops (2010)Pat07Pat07GU991868LPV M46I, I54V, L76V, V82MQ58EL10V, I13A, K20IM, A22AV, E35D, M36I, R41RK, I62IV, L63P, H69K, L89I, T91SG
 Pat08Pat08GU991869NFV, IDV, LPV M46I, I54A, V82M, L90MK43TT4A, L10I, I13V, I15V, L19P, K20I, E35S, M36I, N37E, R41K, V56A, R57K, L63P, H69K, A71V, T74S, V77I, L89I, Q92KG
Barber (2012)6806168061JQ361672LPV I54V, L90LM I13V, K14R, K20I, E35Q, M36I, N37NDEK, R41K, I62IV, L63P, C67E, H69K, A71AV, V82I, L89M, I93IMG
El Annaz (2012)1518315183.PRJN185273IDV52I54V, V82A, L90LML89VL10I, I13V, L19I, K20I, E35D, M36I, N37E, L63P, I64M, H69K, A71VG
Kouri (2012)CU1692-10CU1692-10JQ585441PINA  L10I, T12P, I13V, K14R, K20I, E35D, M36I, L63P, C67S, H69Q, V82I, L89MG
 CU1342-10CU1342-10JQ585425PINA  I13V, K14R, K20I, E35D, M36I, R41K, K43R, L63P, H69K, V82I, L89MG
 CU269-11CU269-11JQ585497PINA  L10I, I13V, K14R, I15V, L19S, K20I, E35D, M36I, D60E, Q61E, L63P, C67N, H69K, L89MG
 CU1326-09CU1326-09JQ585292PINAI54V, V82T, L90ML33F, F53FLL10V, I13V, K20V, E35N, M36I, N37D, R41K, K45V, K55N, L63P, H69K, T74S, L89MG
 CU745-10CU745-10JQ585415PINAI54T W6G, R8G, I13V, K14R, G16A, K20I, E35D, M36I, R41K, K45T, L63P, H69K, K70R, V82I, L89MG
 CU1566-10CU1566-10JQ585436PINAV32I, M46L, I47A, L90M I13AV, K14R, I15V, K20I, E35D, M36I, N37ND, R41K, L63P, H69K, V82I, L89IG
 CU278-11CU278-11JQ585487PINA  L10I, I13V, K14R, I15V, L19LS, K20I, E35D, M36I, D60E, Q61E, L63P, C67N, H69K, L89MG
 CU963-10CU963-10JQ585420PINAM46I, I47V, I54IV I13V, K20I, E35D, M36I, R41K, L63P, H69K, T74TS, V82VI, L89MG
Rawizza (2013)LM4439LM4439KF241483LPV M46I, I47V, I54V, V82SV11I, L24I, F53LL10I, I13V, K14R, I15V, G16A, K20I, E35Q, M36I, N37D, R41K, K55R, R57K, L63P, C67E, H69K, A71V, L89I, T91SG
 PJ1681PJ1681KF241504LPV V32I, I47A L10I, I13V, I15V, K20I, E35Q, M36I, R41RK, K45KR, R57K, L63P, C67E, H69K, A71AV, V82I, L89IG
 LN4711LN4711KF241488LPV  V82NI13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, L89MG
 OU8939OU8939KF241475LPV M46I, I50V, I54V, L76V, L90LML23I, L33F, F53LI13V, K20IL, E34D, E35Q, M36I, N37E, R41K, R57K, Q61QH, L63P, C67E, H69R, T74TS, V82I, L89MG
 LN0609LN0609KF241484LPV M46I, I54V, V82SL24I, K43TL10V, I13V, K14R, G16GA, K20I, E35D, M36I, R41K, R57K, I62V, L63P, C67E, H69R, I72V, T74A, L89MG
 PJ8953PJ8953KF241508LPV M46MI, I54V, V82IS I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, Q61H, L63P, C67E, H69K, L89MG
 LL6229LL6229KF241481LPV L90MF53FILI13V, K14R, K20I, E35D, M36I, N37NK, R41K, L63P, C67E, H69K, V82I, L89MG
 PJ4671PJ4671KF241502LPV M46I, I54V, V82TL24IL10I, I13V, K14R, G17E, K20I, E35Q, M36I, R41K, R57K, I62V, L63P, C67E, H69K, L89MG
 LL3229LL3229KF241463LPV M46I, I50IV, I54IV, V82IST74TPL10M, I13V, K14R, K20I, E35H, M36I, R41K, R57K, Q61QH, L63P, C67E, H69K, A71AV, L89MG
 PJ8430PJ8430KF241500LPV   I13V, K14R, K20I, E35Q, M36I, N37D, R57K, L63P, C67E, H69K, V82I, L89MG
 PJ9611PJ9611KF241501LPV I54V, V82IML24IL10I, I13V, K14R, L19I, K20I, E35Q, M36I, N37D, R41K, R57K, Q61QH, L63P, I64M, C67E, H69K, K70R, L89MG
 LN6370LN6370KF241470LPV   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89MG
Van Zyl (2013)18282545KC423741LPV26I54V, V82M L10I, I13V, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, A71T, L89IG
Grossman (2014)10431043 NFV, LPV52M46I, I54V, V82F, L90M I13V, K14R, K20I, E35H, M36I, N37D, R41K, K55R, L63P, C67E, H69K, A71I, L89I, I93MG