<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L63A
Rx PI-naive
IncludeMixtures No
References 10
Patients 15
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Machado (2004)N72N72AY569898None   K14E, I15L, M36I, R41K, L63A, H69K, K70R, L89MG
Holguin (2005)34778-022_34778-02AY248308None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, I62V, L63A, C67E, H69K, V82I, L89MG
Aghokeng (2009)HG_0568HG_0568GU191662None   I13V, K14R, G17E, Q18QH, L19I, K20I, E34K, M36I, N37D, K43R, Q61N, I62M, L63A, I64IM, C67E, H69K, V77I, L89MG
Cuevas (2009)X2496_1X2496_1GU326112None   T12V, E35D, R41RK, R57K, I62V, L63AG
Hawkins (2009)Q160ZZQ160FJ931222None   L10I, I13V, K14R, K20I, E35Q, M36I, N37E, R41K, K45R, R57K, L63A, C67E, H69K, V82I, L89MG
 R5ZZR5FJ931365None   I13V, K20I, E35Q, M36I, R41K, R57K, L63A, C67E, H69R, V82I, L89MG
Charpentier (2011)147CP 001 498 None   I13V, L19IV, K20I, E35D, M36I, R41K, L63A, C67S, H69K, K70R, V77I, V82I, L89MG
Hamers (2011)CP076303535CP076303535HQ994016None   I13V, K20I, E35Q, M36I, R41K, R57K, L63A, I64M, C67E, H69K, V82I, L89MG
 CP076305173CP076305173HQ994125None   T12TK, I13V, K20I, M36I, N37D, R41K, L63A, I64M, C67S, H69R, K70R, V82I, L89MG
Chamberland (2012)D369TD369THQ267655None   I13V, K14R, G17GE, K20I, M36I, R41RK, L63A, C67S, H69K, V82I, L89MG
Ugbena (2012)2-1-0602-1-060JX084176None   K20I, E35Q, M36I, N37D, R41K, R57K, L63A, C67E, H69K, K70KR, V82I, L89MG
 2-1-0932-1-093JX084208None   I15V, K20I, E35Q, M36I, N37D, R41K, R57K, L63A, C67E, H69R, V82I, L89MG
 1-1-1571-1-157JX084094None   K20I, E35Q, M36I, N37ND, R41K, R57K, L63A, C67E, H69K, V82I, L89MG
 1-1-1181-1-118JX084058None   K20I, E35N, M36I, R41K, R57K, L63A, C67E, H69K, I72IV, V82I, L89MG
Imade (2013)ZZRJ039ZZRJ039KC755258None   L10M, I13V, K20I, E35Q, M36I, R41K, R57K, L63A, C67E, H69K, V82I, L89MG