<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation Q58E
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 11
Isolates 12
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Montes (2004)MB_patHEN02_HEN716AJ577914NFV, LPV85I54V, L90MQ58EI13V, K20I, E35G, M36I, R41K, H69K, K70R, V82I, L89IG
Non-B Workgroup (2005)PL887561905AY900995IDV M46I, I54V, V82T, I84VQ58EL10I, I13V, K20I, E35D, M36I, R41K, L63P, I66F, H69K, A71AV, T74K, L89MG
 PL846867575 RTV74I54V, L90MQ58EI13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, V82I, L89MG
 PL2132483562 IDV252M46I, V82AQ58EL10LV, I13V, K14R, K20I, E21K, E35D, M36I, R41K, R57K, I62V, I64M, H69K, L89MG
 PL28120100793 LPV39M46MI, I54V, L76VL24LI, Q58EL10I, I13V, K20I, E35D, M36I, R41K, L63P, H69K, V82I, L89MG
 PL2983754989 SQV, RTV282M46L, V82A, L90MQ58EL10LV, T12D, I15V, G16GA, K20R, M36I, N37D, D60DE, L63P, H69KG
  76079 SQV, RTV, Unknown>282M46L, I54V, V82A, L90MF53FL, Q58E, G73CSL10V, T12D, I15V, G16A, L19P, K20I, E21K, M36I, N37D, D60N, L63P, H69K, A71AVG
 PL3432698448 IDV, NFV180I54V, V82ML24I, Q58E, L89MVL10I, I13V, K14R, K20I, E35D, M36I, R41K, Q61N, L63T, H69KG
Baxter (2006)48-80768076-30925DQ879086PINAM46I, I54V, L76V, I84VQ58EL10I, I13V, K14R, I15V, K20I, E35N, M36I, N37D, R57RK, D60Q, L63P, H69K, V82I, L89MG
Knops (2010)Pat04Pat04GU991865NFV D30NQ58E, N88DI13V, K20I, E35N, M36I, R41K, K45R, H69K, K70R, V82I, L89MG
 Pat07Pat07GU991868LPV M46I, I54V, L76V, V82MQ58EL10V, I13A, K20IM, A22AV, E35D, M36I, R41RK, I62IV, L63P, H69K, L89I, T91S, F99LG
Kouri (2012)CU1288-10CU1288-10JQ585421PINAM46I, I54L, I84VV11I, L33F, Q58EL10I, I13V, K14R, I15V, G16E, L19P, K20V, E35N, M36I, N37D, K55R, R57RK, Q61H, L63S, H69K, K70R, I72IM, I85V, L89MG