<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation G48V
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 8
Isolates 9
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Snoeck (2002)BE2BE2AF338979IDV, SQV, RTV, NFV109V32I, I47V, G48V, I54V, V82ATF53FL, L89VL10V, I13V, L19IT, K20I, M36I, R41K, K55H, L63P, C67S, H69R, A71IVG
Montes (2004)MB_patRAM01_RAM707AJ577979Unknown, RTV, IDV>90M46L, G48V, I54V, V82T L10V, I13V, K20I, M36I, R41K, I66F, H69K, K70R, L89MG
  02_RAM705AJ577980Unknown, RTV, IDV>120M46L, G48V, I54V, V82T L10V, I13V, K20I, M36I, N37D, R41K, I66F, H69K, K70R, L89MG
Non-B Workgroup (2005)PL1945480060 Unknown, LPV>22M46L, G48V, I54V, V82S, I84IV, L90ML89VL10LIV, I13AV, K14R, K20I, M36I, N37D, R41EK, I62V, H69K, K70KE, A71V, G73GE, T74S, Q92QKG
 PL2909097083 IDV, NFV, SQV, RTV179M46L, G48V, I54V, V82T L10I, I13V, K14R, K20I, E35DN, M36V, R41Q, H69K, K70E, A71V, L89I, I93LG
 PL4236173571 RTV, IDV160M46L, G48V, I54V, V82SK43TL10I, I13A, K14R, K20I, E35D, M36I, R41K, I62V, I66F, H69K, T74S, L89IG
Baxter (2006)48-33183318-30924DQ878218PINAG48V, I54V, V82M, L90MK43T, T74PL10V, T12TK, I13V, K20I, E35D, M36IV, N37D, R41K, Q61QH, I62V, C67E, H69K, L89MG
Knops (2010)Pat14Pat14GU991875SQV, LPV M46L, G48V, I54V, V82S, L90MK43TL10I, T12K, I13V, I15V, K20I, E35N, M36I, N37D, R41K, Q61HN, L63C, C67W, H69K, T74S, L89IG
Rawizza (2013)LM8689LM8689KF241468LPV M46ML, G48V, I54V, V82STK43KTL10I, I13V, I15IV, L19I, K20I, M36I, R41K, Q61DE, I64M, C67S, H69K, A71V, L89M, I93MG