<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation K43R
Rx PI-naive
IncludeMixtures No
References 39
Patients 81
Isolates 82
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Holguin (2002)AH_R2637AH_R2637AF354040None   I13A, K14R, L19I, K20I, M36I, N37D, R41K, K43R, I64M, C67E, H69K, V82I, L89MG
 AH_19804AH_19804AF354004None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, I64M, H69K, L89MG
Parreira (2004)PR_Pat10PR535014AJ535014None   I13V, K14R, L19Q, K20I, E35D, M36I, R41K, K43R, H69K, K70R, V82I, L89MG
 PR_Pat44PR534997AJ534997None   I13V, K14R, L19Q, K20I, E35D, M36I, R41K, K43R, H69K, K70R, V82I, L89MG
 PR_Pat46PR534998AJ534998None   I13V, K20I, E35D, M36I, R41K, K43R, H69K, V82I, L89MG
Non-B Workgroup (2005)PL3696661541AY900990None   I13V, K14R, L19Q, K20I, E35D, M36I, R41K, K43R, H69K, K70R, V82I, L89MG
 PL4293874996 None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, L63S, I64M, H69K, L89MG
Chin (2006)KRC31063106_0312DQ660458None   L10V, I13V, K20I, M36I, R41K, K43R, L63P, H69K, T74A, L89M, I93LG
Marechal (2006)JF_057JF_057DQ443663None  V11IT12K, I13V, L19T, K20I, E35G, M36I, N37D, R41K, K43R, C67S, H69K, V82I, L89MG
Ojesina (2006)AIO_DDJ025AIO_DDJ025DQ273925None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, L63C, H69K, L89MG
Derache (2008)BKO-943BKO-943EU330678None   I13V, K20I, E35D, M36I, R41K, K43R, H69K, I72M, T74S, L89MG
Holguin (2008)1980400SP-19804DQ926898None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, I64M, H69K, L89MG
Sylla (2008)D610D610_C1DQ991657None   I13V, K14R, K20I, E35N, M36I, R41K, K43R, C67M, H69K, L89MG
  D610_C2DQ991658None   I13V, K14R, K20I, E35N, M36I, R41K, K43R, C67M, H69K, L89MG
Aghokeng (2009)HG_0293HG_0293GU191664None   T12N, I13V, K14R, I15V, K20I, E35D, M36I, R41K, K43R, R57K, D60E, L63P, C67E, H69K, L89MG
Avi (2009)N49N49FJ153941None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 N50N50FJ153942None   I13V, K14R, G17D, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 N75N75FJ153950None   L10I, I13V, K14R, G16E, G17E, K20I, E35D, M36I, R41K, K43R, L63H, I64M, H69K, L89M, I93LG
 U14U14FJ153969None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63P, H69K, L89MG
 U65U65FJ153992None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 U77U77FJ153995None   I13V, K14R, G17E, K20I, M36I, R41K, K43R, L63H, H69K, V82I, L89MG
Hawkins (2009)P613ZZP613FJ931127None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, R57K, I64L, H69K, T74S, L89MG
Tebit (2009)TR72TR72FJ577277None   I13V, K14R, K20I, M36I, N37D, R41K, K43R, H69K, K70R, L89MG
Yaotse (2009)HT03406TG.HT034FM955680None   I13V, K14R, I15V, G16E, K20I, E35D, M36I, R41K, K43R, I64M, H69K, L89MG
Diop-Ndiaye (2010)1720-hald1720-haldFN599788None   I13V, K14R, K20I, M36I, N37D, R41K, K43R, H69K, K70R, V82I, L89MG
Djoko (2010)GQ02708GQ027FN557335None   L10I, I13V, K14R, I15IV, K20I, E35KQ, M36I, N37D, R41K, K43R, R57K, L63P, C67E, H69KQ, L89MG
Knops (2010)Pat16Pat16GU991877None   T4S, I13V, K14KR, K20I, M36I, N37D, R41K, K43R, I64M, C67Y, H69K, V82I, R87RG, L89MG
Aghokeng (2011)HJ1814HJ1814JN639457None   I13V, K14R, K20I, M36I, R41K, K43R, L63PS, H69K, K70KR, V82I, L89MG
Avi (2011)034u034uGQ926609None   I13V, K14R, G16E, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 041u041uGQ926613None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 061u061uGQ926628None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 079u079uGQ926641None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, I72V, L89MG
 101u101uGQ926661None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 146u146uGQ926691None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 148u148uGQ926692None   I13V, K14R, G17E, K20I, E35DN, M36I, R41K, K43R, L63Q, I64M, E65D, H69K, K70R, L89MG
 155u155uGQ926699None   L10I, I13V, K14R, I15V, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, I72V, V82I, L89M, F99LG
Dagnra (2011)08TG.E501608TG.E5016FR715272None   T12S, I13V, K20I, M36I, R41K, K43R, L63H, H69K, L89MG
Hamers (2011)300566CP076300566HM119973None   Q18K, K20I, E35V, M36I, N37D, R41K, K43R, I64M, C67E, H69K, V82I, L89MG
 CP076305225CP076305225HQ994158None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K43R, R57K, Q61H, L63P, C67E, H69K, V82I, L89MG
Machado (2012)CUPL1011CUPL1011HQ655388None   I13V, I15V, K20I, E35D, M36I, R41K, K43R, I64M, H69K, V82I, L89MG
Oliveira (2012)05CVHAN1705CVHAN17JF267442None   I13V, L19Q, K20I, E35D, M36I, R41K, K43R, H69K, V82I, L89MG
 05CVHAN1905CVHAN19JF267443None   I13V, I15V, K20I, M36I, R41K, K43R, H69K, V82I, L89MG
Sagoe (2012)KAF41KAF41HQ170613None   I13V, K14R, K20I, M36I, R41K, K43R, L63P, C67S, H69K, V82I, L89M, T96TAG
Somda (2012)44-170-2044-170-20HG529936None   I13V, K20I, E35D, M36I, K43R, L63P, C67E, H69K, V77I, V82I, L89IG
Avi (2013)132132JX431707None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 121121JX431701None   I13V, K14R, G17E, K20I, M36I, R41K, K43R, L63H, H69K, L89MG
 250250JX431778None   T12K, I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, V82I, L89MG
 137137JX431711None   I13V, K14R, G17E, K20I, M36I, R41K, K43R, L63H, I64M, H69K, I72V, L89MG
 2323JX431629None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, R57RK, L63H, H69K, V77VI, L89MG
 212212JX431755None   I13V, K14R, I15V, G17E, K20I, E35D, M36I, R41K, K43R, L63H, I64M, H69K, L89MG
 209209JX431754None   I13V, K14R, K20I, E35D, M36I, N37D, R41K, K43R, L63H, H69K, V82I, L89MG
 106106JX431693None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, I64M, H69K, L89MG
 261261JX431783None   I13A, G17E, K20I, M36I, R41K, K43R, L63H, H69K, A71T, L89I, Q92KG
 8181JX431675None   L10I, I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, I64M, H69K, L89M, F99LG
 254254JX431781None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, K43R, L63H, H69K, V82I, L89MG
 276276JX431795None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63P, H69K, A71V, I72T, L89I, Q92KG
 190190JX431741None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, H69K, K70R, V82I, L89MG
 241241JX431772None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, I64M, H69K, L89MG
 284284JX431800None   I13V, I15V, K20I, E35D, M36I, R41K, K43R, L63H, H69K, I72T, L89MG
 5050JX431642None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, L63H, I64M, C67W, H69K, L89M, I93LG
 279279JX431797None   I13V, K14R, G16E, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MG
 9696JX431662None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, L63H, I64M, H69K, L89MG
 357357JX431854None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, I72V, L89MG
 142142JX431714None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, K43R, L63P, H69K, K70KR, L89MG
 313313JX431821None   I13V, G17E, K20I, E35N, M36I, R41K, K43R, L63Q, H69K, L89MG
Frentz (2013)EHR-62457EHR-62457JX300581None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K43R, R57K, I62IV, L63PS, C67E, H69R, V82I, L89MG
Pircher (2013)B1123B1123JX110310None   I13V, K14R, K20I, E35D, M36I, N37D, R41K, K43R, R57K, C67E, H69K, V82I, L89M, T91VG
Aghokeng (2014)TG-5-393TG-5-393KC350299None   I13V, K14R, G17D, K20I, M36I, K43R, L63P, H69K, L89MG
 TG-3-628TG-3-628KC350318None   I13V, I15V, K20I, M36I, R41K, K43R, Q61E, I64M, C67S, H69K, K70R, V82I, L89MG
Bartolo (2014)09AOHDP9609AOHDP96KF853891None   I13AV, K14KR, I15V, K20I, E35D, M36I, R41K, K43R, H69K, V82I, L89MG
Dauwe (2015)06_0706006_07060KT863538None   I13V, K14KR, K20I, M36I, R41K, K43R, L63HPSY, I64M, H69K, L89MG
 NA_09007NA_09007KT863932None  N83NDI13V, K20I, E35D, M36I, R41K, K43R, C67H, H69K, V82I, L89MG
 NA_05_64NA_05_64KT863919None  V11IL10I, I13V, K14R, G16E, K20I, E35G, M36I, R41K, K43R, H69Q, L89MG
Hora (2015)DE01405ES002DE01405ES002KC473837None   I13V, K14R, K20V, E35D, M36I, R41K, K43R, G68E, H69K, V82I, L89MG
Kouri (2015)AIDS-RP45AIDS-RP45KP688122None   L10I, I13V, K20I, E35D, M36I, R41K, K43R, C67CY, H69K, V82I, L89MG
Abdellaziz (2016)1538515385KT339051None   T12K, I13V, K14R, G16E, K20I, E35D, M36I, R41K, K43R, H69K, L89MG
 18718HB18718HBKT338973None   L10LV, I13V, I15V, G16E, L19LP, K20I, M36I, R41K, K43R, Q61H, L63LAPV, H69K, K70R, I72T, L89MG
Castley (2016)P149623084JP149623084JKT229114None   L10M, I13V, L19S, K20I, M36I, K43R, C67E, H69K, V82I, L89M, Q92QL, L97IG
Chow (2016)MYNBB057MYNBB057KU535938None   L10V, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, K43R, R57K, I62V, I64M, C67E, H69K, V82I, L89MG
Hattori (2016)C09_110936C09-51110936-1AB865342None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K43R, R57K, L63P, C67E, H69K, V82I, L89MG
Hoenigl (2016)V0838187V0838187KU574432None   I13V, I15V, K20I, M36I, N37D, R41K, K43R, I64L, C67S, H69K, V77VI, L89MG
Lam (2016)2103200921032009KR868132None   I13V, K14KR, K20I, M36I, N37ND, R41K, K43R, L63LDHV, C67IM, H69K, V82I, I85IM, L89MG