<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation K43R
Rx PI-naive
IncludeMixtures No
References 11
Patients 15
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Holguin (2002)AH_R2637AH_R2637AF354040None   I13A, K14R, L19I, K20I, M36I, N37D, R41K, K43R, I64M, C67E, H69K, V82I, L89MG
Parreira (2004)PR_Pat10PR535014AJ535014None   I13V, K14R, L19Q, K20I, E35D, M36I, R41K, K43R, H69K, K70R, V82I, L89MG
 PR_Pat44PR534997AJ534997None   I13V, K14R, L19Q, K20I, E35D, M36I, R41K, K43R, H69K, K70R, V82I, L89MG
 PR_Pat46PR534998AJ534998None   I13V, K20I, E35D, M36I, R41K, K43R, H69K, V82I, L89MG
Non-B Workgroup (2005)PL3696661541AY900990None   I13V, K14R, L19Q, K20I, E35D, M36I, R41K, K43R, H69K, K70R, V82I, L89MG
Marechal (2006)JF_057JF_057DQ443663None  V11IT12K, I13V, L19T, K20I, E35G, M36I, N37D, R41K, K43R, C67S, H69K, V82I, L89MG
Aghokeng (2009)HG_0568HG_0568GU191662None   I13V, K14R, G17E, Q18QH, L19I, K20I, E34K, M36I, N37D, K43R, Q61N, I62M, L63A, I64IM, C67E, H69K, V77I, L89MG
 HG_0293HG_0293GU191664None   T12N, I13V, K14R, I15V, K20I, E35D, M36I, R41K, K43R, R57K, D60E, L63P, C67E, H69K, L89MG
Diop-Ndiaye (2010)1720-hald1720-haldFN599788None   I13V, K14R, K20I, M36I, N37D, R41K, K43R, H69K, K70R, V82I, L89MG
Hamers (2010)300441CP076300441HM119863None   I3V, L10I, G16A, M36I, N37D, R41K, K43R, D60N, Q61D, C67E, H69K, T74S, L89M, I93LG
 300566CP076300566HM119973None   Q18K, K20I, E35V, M36I, N37D, R41K, K43R, I64M, C67E, H69K, V82I, L89MG
Knops (2010)Pat16Pat16GU991877None   T4S, I13V, K14KR, K20I, M36I, N37D, R41K, K43R, I64M, C67Y, H69K, V82I, R87RG, L89MG
Hamers (2011)CP076305225CP076305225HQ994158None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K43R, R57K, Q61H, L63P, C67E, H69K, V82I, L89MG
Machado (2012)CUPL1011CUPL1011HQ655388None   I13V, I15V, K20I, E35D, M36I, R41K, K43R, I64M, H69K, V82I, L89MG
Frentz (2013)EHR-62457EHR-62457JX300581None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K43R, R57K, I62IV, L63PS, C67E, H69R, V82I, L89MG

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