<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation E35N
Rx PI-naive
IncludeMixtures No
References 36
Patients 79
Isolates 81
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ellenberger (1999)El-IC3670IC3670AF000491None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, L89MG
 El-IC3541IC3541AF000482None   I13V, K20I, E35N, M36I, R41K, H69K, K70R, L89MG
Cuevas (2002)CU103CU103AF425484None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, V82I, L89MG
Non-B Workgroup (2005)UK1523UK1523AY900808None   I13V, K14R, K20I, E35N, M36I, R41K, R57K, L63P, H69K, K70R, L89MG
 PL3602359402AY900977None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, V82I, L89MG
 PL48594106338 None   I13V, K14R, K20V, E35N, M36I, R41K, H69K, K70R, L89MG
 PL5206098324 None   I13V, K14R, K20I, E35N, M36I, R41K, R57RK, H69K, V82I, L89MG
Punzi (2005)CAR-70CAR-70AY626960None   L10V, I13V, K14R, I15V, K20R, E35N, M36V, R41K, L63T, H69K, I72V, L89MG
Tebit (2006)A123A123DQ682718None   L10V, I13V, K14R, G17E, L19I, K20I, E35N, M36I, R57K, H69K, L89MG
Vidal (2006)NV_KP00902.KP009AM041027None   I13V, K14R, K20I, E35N, M36L, R41K, L63P, H69K, V82I, L89MG
Derache (2007)12041204EF064475None   T12Q, I13V, K14R, Q18E, K20I, E35N, M36I, G40E, R41K, L63P, E65D, H69K, L89MG
 12761276EF064515None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, L89MG
Palma (2007)Pt1863343 None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, V82I, L89MG
 Pt2666969 None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, V82I, L89MG
 Pt5282230 None   I13V, K14R, K20IM, E35N, M36I, R41K, K45KR, H69K, V82I, L89MG
 Pt215138501 None   I13V, I15V, K20I, E35N, M36I, P39S, R41K, H69K, V82I, L89MG
Delgado (2008)GH_048GH_048EU177920None   I13V, K14R, K20I, E35N, M36I, R41K, L63Q, H69K, L89MG
Derache (2008)BKO-1038BKO-1038EU330723None   L10I, I13V, K20I, E35N, M36I, R41K, L63T, E65D, C67S, H69K, I72T, V82I, L89MG
Holguin (2008)SP47-353742SP47-353742EU342809None   I13V, K14R, I15V, K20I, E35N, M36I, R41K, I62V, I64M, G68E, H69R, I72V, L89MG
Sylla (2008)D610D610_C1DQ991657None   I13V, K14R, K20I, E35N, M36I, R41K, K43R, C67M, H69K, L89MG
  D610_C2DQ991658None   I13V, K14R, K20I, E35N, M36I, R41K, K43R, C67M, H69K, L89MG
 D615D615_C1DQ991659None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, L89MG
  D615_C2DQ991660None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, L89MG
Aghokeng (2009)CYN1072CYN1072GU191597None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, V82I, L89M, I93VG
Avi (2009)N72N72FJ153947None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63Q, H69K, L89MG
 U17U17FJ153971None   I13V, K14R, G17E, K20I, E35N, M36I, L63H, H69K, L89MG
Hawkins (2009)R258ZZR258FJ931403None   L10LI, I13V, K14R, K20I, E35N, M36I, N37D, R41K, C67E, H69K, V82I, L89MG
Vercauteren (2009)pt14894348081906GQ399535None   I13V, K14R, K20I, E35N, M36I, R41K, L63P, H69K, L89MG
 pt14014849955531GQ399623None   I13V, K14R, K20I, E35N, M36I, R41K, R57K, L63P, G68E, H69K, K70R, L89MG
 pt10107149224606GQ400014None  I84IMI13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, L89MG
Yaotse (2009)HT07006TG.HT070FM955704None   I13V, K14R, G16E, K20I, E35N, M36I, N37D, R41K, H69K, K70R, L89MG
Yebra (2009)SP22-353742SP22-353742EU255507None   I13V, K14KR, I15V, K20I, E35N, M36I, R41K, I62V, I64M, G68E, H69R, I72V, L89MG
Avi (2011)033u033uGQ926608None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63Q, H69K, K70R, L89MG
 040u040uGQ926612None   I13V, K14R, I15V, G17E, K20I, E35N, M36I, R41K, L63P, H69K, L89MG
 050u050uGQ926620None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63Q, I64M, H69K, K70Q, L89M, Q92KG
 021u021uGQ926643None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63Q, I64M, H69K, L89MG
 102u102uGQ926662None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, K70R, L89MG
 140u140uGQ926686None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, L89MG
 167u167uGQ926709None   I13V, K14R, I15V, G17E, K20I, E35N, M36I, R41K, L63H, H69K, L89MG
 197u197uGQ926732None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, L89MG
de Felipe (2011)SE113PR_SE113JF338714None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, K70KR, L89MG
Hamers (2011)CP076301709CP076301709HQ993704None   L10I, T12P, I13V, K14R, I15V, G16X, K20I, E35N, M36I, R41K, I62IV, L63PS, C67E, H69K, V82I, L89MG
Betancor (2012)HCIII-00353742HCIII-00353742JX271327None   I13V, K14KR, I15V, K20I, E35N, M36I, R41K, I62V, I64M, G68E, H69R, I72V, L89MG
De Gascun (2012)IRL55067IRL55067JN622367None   I13V, K20I, E35N, M36I, R41K, I64M, H69K, L89MG
Machado (2012)CUPL1056CUPL1056JN000028None   T12A, I13V, K14R, K20I, E35N, M36I, R41K, H69K, K70R, V82I, L89MG
 CUPL1057CUPL1057JN000029None   T12A, I13V, K14R, K20I, E35N, M36I, R41K, H69K, K70R, V82I, L89MG
 CUPL1091CUPL1091JN000063None   T12A, I13V, K14R, K20I, E35N, M36I, R41K, L63P, H69K, L89M, N98HG
 CUPL1154CUPL1154JX194233None   I13V, K14R, I15V, K20I, E35N, M36I, R41K, I64M, H69K, L89MG
Sagoe (2012)KAF130KAF130HQ170623None   L10I, I13V, G17E, K20I, E35N, M36I, R41K, L63P, H69N, V77I, L89MG
Somda (2012)44-276-2144-276-21HG529943None   I13V, L19LP, K20I, E35N, M36I, R41K, H69K, L89MG
Avi (2013)9191JX431666None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, I72V, L89M, F99LG
 100100JX431658None   I13V, K14R, G17D, K20I, E35N, M36I, R41K, L63H, H69K, L89MG
 134134JX431710None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, L89MG
 189189JX431740None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, K70R, L89MG
 230230JX431764None   T12I, I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, L89MG
 169169JX431724None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, K70R, L89MG
 254254JX431781None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, K43R, L63H, H69K, V82I, L89MG
 331331JX431835None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, I72V, L89M, Q92KG
 339339JX431839None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63P, H69K, L89MG
 320320JX431826None   I13V, K14R, G17E, K20I, E35N, M36I, N37NI, R41K, L63Q, H69K, L89MG
 313313JX431821None   I13V, G17E, K20I, E35N, M36I, R41K, K43R, L63Q, H69K, L89MG
 204204JX431750None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63H, H69K, L89MG
Billong (2013)MR061MR061KF192116None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, V82I, L89MG
Frentz (2013)EHR-27864EHR-27864JX300024None   I13V, K20I, E35N, M36I, R41K, H69K, L89MG
 EHR-39409EHR-39409JX300208None   L10I, I13V, K14KR, K20I, E35N, M36I, R41K, I62IV, L63T, C67E, H69Q, I72T, V77I, V82I, L89MG
Kebe (2013)SNA3-196SNA3-196JN193494None   I13V, K14R, I15IV, K20I, E35N, M36I, R41K, L63S, I64M, H69K, L89MG
 SNA3-195SNA3-195HM002541None   I13V, K14R, I15IV, K20I, E35N, M36I, R41K, L63S, I64M, H69K, L89MG
Nii-Trebi (2013)894894AB751460None   I13V, I15V, K20I, E35N, M36I, R41K, I64IM, H69K, V77VI, L89MG
Theys (2013)9832498324 None   I13V, K14R, K20I, E35N, M36I, R41K, R57RK, H69K, V82I, L89MG
 BM28734BM28734 None   I13V, K20I, E35N, M36I, N37D, R41K, C67Y, H69K, V82I, L89MG
 63196319KY386678None   I13V, K14R, K20I, E35N, M36I, P39PS, R41K, I62V, L63P, G68E, H69K, K70R, L89MG
 129127129127 None   T12TA, I13V, K14R, K20I, E35N, M36I, R41K, L63LFPS, H69K, V82VI, L89IMG
 152776152776 None   I13V, K20I, E35N, M36I, R41K, Q61QR, H69K, L89M, N98NDG
Aghokeng (2014)TG-1-012TG-1-012KC350201None   T12A, I13V, K14R, I15V, L19LQ, K20I, E35N, M36I, R41K, R57K, L63P, H69K, L89MG
 TG-3-221TG-3-221KC350292None  M46MRI13V, K20I, E35N, M36I, N37D, R41K, C67CW, H69K, V77I, L89MG
 TG-1-041TG-1-041KC350213None   T12TA, I13V, K20I, E35N, M36I, R41K, R57K, I64M, H69K, L89MG
 TG-5-668TG-5-668KC350305None   I13V, K14R, G16E, K20I, E35N, M36I, R41K, H69K, K70R, V77I, L89MG
Diallo (2015)1-1-1181-1-118JX084058None   K20I, E35N, M36I, R41K, R57K, L63A, C67E, H69K, I72IV, V82I, L89MG
Kouri (2015)N_AIDS13N_AIDS13KP688159None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, H69K, L89MG
 AIDS-RP41AIDS-RP41KP688118None   I13V, K14R, K20I, E35N, M36I, R41K, H69K, V82I, L89MG
Abdellaziz (2016)1520515205KT339052None   T12S, I13V, K14R, I15V, L19I, K20I, E35N, M36I, R41K, L63P, H69K, K70GR, L89MG