<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation E35N
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 17
Isolates 18
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Montes (2004)MB_patVIG02_VIG701AJ578178SQV, RTV, IDV252M46I, I54A, V82T L10I, I13V, K14R, K20I, E35N, M36I, N37D, R41K, Q61H, L63P, C67E, H69K, I72V, T74S, L89MG
Non-B Workgroup (2005)PL3476656768AY900714NFV73L90M I13V, K20I, E35N, M36I, R41K, H69K, K70R, A71T, V82I, L89IG
 PL3606959512AY900981NFV I54V, L90M I13V, K20I, E35N, M36I, N37ND, R41K, H69K, T74S, V82I, L89IG
 PL3655160625AY900985NFV L90M I13V, K14R, G17E, K20I, E35N, M36I, R41K, I62V, L63P, H69K, K70R, A71T, V82I, L89IG
 PL1618161896 IDV, SQV134  I13V, K14KR, I15IV, K20I, E35N, M36I, R41K, H69K, I72T, V82I, L89MG
 PL2647363176AY901007SQV, NFV, IDV, RTV, LPV I54V, V82F, L90ML89VL10I, I13V, K14R, K20I, E35N, M36I, N37ND, R41K, L63P, H69K, A71V, Q92QKG
  89488 SQV, NFV, IDV, RTV, LPV, UnknownNAM46I, I50V, I54V, V82F, L90ML89VL10I, I13A, K14R, K20IT, A22AV, E35N, M36I, N37D, R41K, L63P, I66V, C67CR, H69K, K70KT, A71V, I85IV, Q92KG
 PL3857565077AY901037NFV169L90M I13V, K14R, I15V, K20IV, E35N, M36I, R41K, H69K, K70KR, A71T, V82I, L89IG
 PL3865565229 NFV, IDV, RTV L90M I13V, K20I, E35N, M36I, R41K, L63C, H69K, V82I, L89MG
 PL3595467123AY901045SQV, IDV, NFV I54V, L90M I13V, K14R, K20I, E35N, M36I, R41K, K45R, H69K, A71AV, V82I, L89IG
 PL1920995879 NFV78  I13V, K14R, K20I, E35N, M36I, R41K, H69K, V82I, L89MG
 PL2632060887 NFV171N88S I13V, K14R, K20I, E35N, M36I, R41K, I62V, I64V, H69K, T74S, V82I, L89MG
 PL3965167522 NFV151I54V, L90M I13V, K14R, K20I, E35N, M36I, R41K, K45KR, I62IV, H69K, A71AV, T74S, V82VI, L89IG
 PL4307775315 NFV224M46L, I54V, L90M I13V, K14R, L19I, K20I, E35N, M36I, R41K, K55KR, R57RK, H69K, V82I, L89MG
Baxter (2006)48-80768076-30925DQ879086PINAM46I, I54V, L76V, I84VQ58EL10I, I13V, K14R, I15V, K20I, E35N, M36I, N37D, R57RK, D60Q, L63P, H69K, V82I, L89MG
Knops (2010)Pat04Pat04GU991865NFV D30NQ58E, N88DI13V, K20I, E35N, M36I, R41K, K45R, H69K, K70R, V82I, L89MG
 Pat11Pat11GU991872IDV D30N, I54VL33I, N88D, L89VI13V, L19P, K20I, E35N, M36I, N37D, R41K, K43R, K45Q, H69K, T74S, V82IG
 Pat14Pat14GU991875SQV, LPV M46L, G48V, I54V, V82S, L90MK43TL10I, T12K, I13V, I15V, K20I, E35N, M36I, N37D, R41K, Q61HN, L63C, C67W, H69K, T74S, L89IG

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