<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L10V
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 14
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Snoeck (2002)BE2BE2AF338979IDV, SQV, RTV, NFV109V32I, I47V, G48V, I54V, V82ATF53FL, L89VL10V, I13V, L19IT, K20I, M36I, R41K, K55H, L63P, C67S, H69R, A71IVG
Montes (2004)MB_patCHRI01_CHR723AJ577864SQV, IDV, NFV, APV, LPV181M46I, I54V, V82A, L90M L10V, I13V, K20I, A22V, E35D, M36I, N37D, R41K, K43R, I62V, L63P, H69K, A71V, L89I, T91S, T96AG
 MB_patRAM01_RAM707AJ577979Unknown, RTV, IDV>90M46L, G48V, I54V, V82T L10V, I13V, K20I, M36I, R41K, I66F, H69K, K70R, L89MG
  02_RAM705AJ577980Unknown, RTV, IDV>120M46L, G48V, I54V, V82T L10V, I13V, K20I, M36I, N37D, R41K, I66F, H69K, K70R, L89MG
Non-B Workgroup (2005)PL2983776079 SQV, RTV, Unknown>282M46L, I54V, V82A, L90MF53FL, Q58E, G73CSL10V, T12D, I15V, G16A, L19P, K20I, E21K, M36I, N37D, D60N, L63P, H69K, A71AVG
Baxter (2006)48-12171217-30701DQ877755PINAI54V, V82A, L90MV11I, F53LL10V, T12K, I13V, K14R, G16E, K20I, L33L_L, E35D, M36I, R41K, I62V, H69K, A71V, L89IG
 48-33183318-30924DQ878218PINAG48V, I54V, V82M, L90MK43T, T74PL10V, T12TK, I13V, K20I, E35D, M36IV, N37D, R41K, Q61QH, I62V, C67E, H69K, L89MG
Knops (2010)Pat07Pat07GU991868LPV M46I, I54V, L76V, V82MQ58EL10V, I13A, K20IM, A22AV, E35D, M36I, R41RK, I62IV, L63P, H69K, L89I, T91S, F99LG
 Pat17Pat17GU991878SQV, LPV M46I, I54V, V82A, L90ML33I, L89VL10V, I13A, K20V, A22V, E35D, M36I, N37E, R41K, R57K, I62V, L63LP, H69K, K70R, A71T, T74SG
 Pat19Pat19GU991880LPV M46I, I50V, I54V, V82MV11VI, F53LL10V, T12S, I13V, I15IV, L19P, K20I, E35DN, M36I, R41K, K45V, Q61QH, I64V, C67CY, G68D, H69K, A71V, L89IG
Kouri (2012)CU1326-09CU1326-09JQ585292PINAI54V, V82T, L90ML33F, F53FLL10V, I13V, K20V, E35N, M36I, N37D, R41K, K45V, K55N, L63P, H69K, T74S, L89MG
 CU485-11CU485-11JQ585505PINA  L10V, I13V, K14R, K20I, E35D, M36I, D60E, L63I, H69K, L89MG
 CU545-11CU545-11JQ585508PINA  L10V, I13V, K14R, K20I, E35D, M36I, D60E, L63I, H69K, L89MG
Rawizza (2013)LN0609LN0609KF241484LPV M46I, I54V, V82SL24I, K43TL10V, I13V, K14R, G16GA, K20I, E35D, M36I, R41K, R57K, I62V, L63P, C67E, H69R, I72V, T74A, L89MG
 PJ6749PJ6749KF241460LPV M46L, G48Q, I54V, L76V, I84VF53LL10V, I13A, K14R, I15V, K20I, E35H, M36I, R41K, K55R, R57K, Q61HN, I64V, C67E, H69K, T74S, L89I, T91AG