<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L10I
Rx PI-naive
IncludeMixtures No
References 47
Patients 136
Isolates 136
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Oelrichs (1999)ZA_BLZA_BLAF084936None   L10I, T12K, I13V, K14R, K20I, M36I, N37D, R41K, C67S, H69K, K70R, V82I, L89MG
Si-Mohamed (2000)AS_PINAS_PINAF199287None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, C67N, H69K, V82I, L89MG
Vergne (2000)LV63HPDLV63HPDAJ286982None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V82I, L89M, I93VG
Carr (2001)CM53392CM53392AF377957None  V11IL10I, T12K, I13V, K20I, M36L, N37S, R41K, L63P, C67Y, H69K, K70R, L89IG
Perez-Alvarez (2001)X605X605AF450096None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M, F99LG
Fonjungo (2002)CM218CM218AY051208None   L10I, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, K70R, V82I, L89M, I93LG
 CM16CM16AY051204None   L10I, T12P, I13V, I15V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
 CM129CM129AY051203None   L10I, I13V, K14R, I15V, G16E, K20I, M36I, N37S, R41K, L63V, I64L, C67S, H69K, L89M, I93LG
Holguin (2002)AH_G2721AH_G2721AF354000None   L10I, I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
Njouom (2003)20pro20proAY204325None   L10I, T12K, I13V, K14R, K20I, M36I, N37D, R41K, C67S, H69K, K70R, V82I, L89MG
Eshleman (2004)ABB105ABB105AY444293None   L10I, V11T, I13V, K20I, E35D, M36I, R41K, L63P, H69K, K70KR, L89MG
 ABB55ABB55AY444287None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V82I, L89M, I93VG
Konings (2004)KF_Pat3900CM4857AY359721None   L10I, I13V, K20I, E35D, M36I, R41K, D60E, L63V, C67S, H69R, T74S, L89MG
 KF_Pat4000CM1678AY359722None   L10I, I13V, K20I, E35D, M36I, R41K, D60E, L63V, C67S, H69R, T74S, L89MG
 KF_Pat4500CM926AY359727None   L10I, V11T, I13V, K20I, E35D, M36I, R41K, L63P, H69K, L89MG
Parreira (2004)PR_Pat8PR535005AJ535005None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
Carr (2005)1901LE1901LEAY847419None   L10I, I13V, L19P, K20I, M36I, R41K, H69K, I72M, L89MG
Carr (2005)01NGPL66901NGPL669DQ013280None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89MG
 01NGPL066901NGPL0669DQ168576None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89MG
Holguin (2005)50320-0202_50320-2AY248319None   L10I, I13V, K14R, G17E, K20I, E35Q, M36I, R41K, R57K, L63T, C67E, H69K, V82I, L89MG
Holzmayer (2005)96CMABB5596CMABB55AY772535None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V82I, L89M, I93VG
Non-B Workgroup (2005)PL840761765AY900994None   L10I, I13V, K14KR, K20I, E35D, M36I, R41K, R57K, H69K, V82I, L89MG
 PL3019760249AY900998None   L10I, I13V, K14R, L19P, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 PL4023168728AY901062None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 PL43995101842 None   L10I, I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MG
 PL4877389675 None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 PL5239399133 None   T4S, L10I, I13V, G17E, K20I, E35D, M36I, R41K, L63M, H69K, V82I, L89MG
 PL54239103947 None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, K70R, I72T, V82I, L89MG
Zeh (2005)99NG107599NG1075AY103364None   L10I, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, C67E, H69Q, V82I, L89M, I93LG
 99NG105699NG1056AY103362None   L10I, I13V, K14R, I15V, Q18R, K20I, E35Q, M36I, N37D, R41K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG11999NG119AY103369None   L10I, I13V, K14R, I15V, Q18R, K20I, E35Q, M36I, N37D, R41K, C67E, H69K, V82I, L89M, I93LG
 99NG66899NG668AY103386None   L10I, I13V, K14R, I15V, Q18R, K20I, E35Q, M36I, N37D, R41K, L63P, C67E, H69K, V82I, L89M, I93LG
 99NG78999NG789AY103393None   L10I, I13V, K14R, I15V, Q18R, K20I, E35Q, M36I, N37D, R41K, C67E, H69K, V82I, L89M, I93LG
 99NG82799NG827AY103394None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M, I93LG
Koizumi (2006)YK_04CM024YK_04CM024DQ461834None   Q2P, L10I, I13V, I15V, K20I, E35D, M36I, R41K, D60E, C67S, H69Q, V82I, L89MG
Marechal (2006)JF_131JF_131DQ443709None   L10I, T12R, I13V, L19I, K20I, M36I, N37D, R41K, I64L, C67S, H69K, V82I, L89MG
Vessiere (2006)AV_M10066NAV_M10066NDQ297233None   L10I, V11T, I13V, K14R, K20I, E35D, M36L, R41K, L63P, H69K, L89MG
 AV_M4611NAV_M4611NDQ297271None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, Q61H, L63S, C67E, H69K, V82I, L89M, I93VG
Vidal (2006)NV_KP12202.KP122AM041043None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, L63P, C67E, H69K, V82I, L89MG
 NV_LBIST051LBIST051AM041000None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, L63P, C67E, H69K, V82I, L89MG
Derache (2007)12131213EF064481None   L10I, I13V, K14R, I15V, K20I, E35Q, M36I, N37D, R41K, C67E, H69K, K70R, V82I, L89MG
Palma (2007)Pt1461765 None   L10I, I13V, K14KR, K20I, E35D, M36I, R41K, R57K, H69K, V82I, L89MG
 Pt3673618 None   L10I, T12T*KS, I13V, K14R, I15V, K20I, M36I, N37S, R41K, H69Q, K70KR, V82I, L89MG
 Pt3874047 None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 Pt5181870 None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, R57K, H69K, K70KR, V82I, L89MG
 Pt6084942 None   L10I, I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89M, I93IVG
 Pt109103693 None   L10I, I13V, K20I, M36I, R41K, H69K, K70R, V82I, L89MG
 Pt110104104 None   L10I, I13V, K14R, G17GE, L19I, K20I, E35D, M36I, R41K, L63FV, H69K, V82I, L89MG
 Pt137114363 None   L10I, I13V, K14R, K20I, M36I, R41K, H69K, K70R, V82I, L89MG
 Pt138115484 None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, R57RK, L63LH, H69K, K70KR, V82I, L89MG
 Pt140115533 None   L10I, I13V, K14R, G16E, Q18K, K20I, E35D, M36I, R41K, R57K, H69Q, V82I, L89MG
 Pt149121077 None   L10I, I13V, K14R, K20I, E34Q, E35D, M36I, P39PS, R41K, C67E, H69K, I72IV, V77I, L89MG
 Pt153122456 None   L10I, I13V, K14R, L19T, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 Pt176128813 None   L10I, I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 Pt190132564 None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, C67D, H69K, V82VI, L89MG
 Pt191132662 None   L10I, I13V, I15V, L19LP, K20I, E35D, M36I, R41K, H69KQ, V82I, L89MG
 Pt194133357 None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 Pt197134279 None   L10I, I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69Q, V82I, L89MG
Powell (2007)CMNYU92600CMNYU926EF116594None   L10I, V11T, I13V, K20I, E35D, M36I, R41K, L63P, H69K, L89MG
Derache (2008)BKO-1038BKO-1038EU330723None   L10I, I13V, K20I, E35N, M36I, R41K, L63T, E65D, C67S, H69K, I72T, V82I, L89MG
Holguin (2008)SP42-312587SP42-312587EU255345None   L10I, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89MG
Aghokeng (2009)CYM009CYM009GU191555None   L10I, I13V, I15V, L19I, K20I, E35D, M36I, R41K, L63P, I64IV, C67S, H69K, K70KR, L89MG
 CDG217CDG217GU191617None   L10I, I13V, I15IV, K20I, E35D, M36I, R41K, D60E, H69K, V82I, L89M, I93VG
 DG429DG429GU191639None   L10I, T12A, I13V, K14R, K20I, M36I, R41K, L63P, C67E, H69K, V82I, L89M, I93VG
 HU_0044HU_0044GU191677None   L10I, T12Q, I13V, K14KR, K20I, E35Q, M36I, R41K, C67E, H69K, V82I, L89MG
Bartolo (2009)HJM6301AOHJM63EU068258None   L10I, I13V, L19V, K20I, M36I, R41K, C67N, H69K, V82I, L89MG
 LFA9001AOLFA90EU068271None   L10I, I13V, K20I, E35D, M36I, L63T, H69K, L89MG
 SNS4901AOSNS49EU068304None   L10I, I13V, K20I, E35D, M36I, L63T, H69K, L89MG
 SNS5201AOSNS52EU068306None   L10I, I13V, K20I, M36I, R41K, C67N, H69K, V82I, L89MG
 SNS5401AOSNS54EU068308None   L10I, T12K, I13V, K14R, K20I, M36I, R41K, C67E, H69K, K70R, L89MG
 HM18401AOHM184EU068323None   L10I, T12K, I13V, K14R, I15V, K20I, M36I, N37ND, R41K, L63I, C67G, H69K, V82I, L89MG
Hawkins (2009)P634ZZP634FJ931140None   L10I, T12K, I13V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, K70R, V82I, L89MG
 Q208ZZQ208FJ931210None   L10I, I13V, K14R, I15V, L19I, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, K70R, V82I, L89MG
 Q160ZZQ160FJ931222None   L10I, I13V, K14R, K20I, E35Q, M36I, N37E, R41K, K45R, R57K, L63A, C67E, H69K, V82I, L89MG
 Q165ZZQ165FJ931223None   L10I, I13V, I15V, L19I, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89MG
 Q240ZZQ240FJ931228None   L10I, V11A, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, C67E, H69R, V82I, L89MG
 Q407ZZQ407FJ931230None   L10I, I13V, K20I, M36I, R41K, C67N, H69K, K70R, V82I, L89MG
 Q969ZZQ969FJ931304None   L10I, I13V, K20I, M36I, R41K, C67S, H69K, V82I, L89MG
 Q973ZZQ973FJ931306None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63T, C67E, H69K, V82I, L89MG
 R114ZZR114FJ931310None   L10I, I13V, I15V, G17E, K20I, E35Q, M36I, N37D, R41K, K45R, R57K, L63P, E65Q, C67E, H69K, K70R, V82I, L89MG
 Q411ZZQ411FJ931340None   L10I, I13V, K14R, G17GE, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89MG
 Q982ZZQ982FJ931373None   L10I, I13V, K20I, E35Q, M36I, R41K, K45R, R57K, L63AS, C67E, H69K, V82I, L89MG
 R220ZZR220FJ931380None   L10I, V11A, I13V, K14R, K20I, E35K, M36I, N37D, R41K, R57K, C67E, H69K, V82I, L89MG
 R222ZZR222FJ931381None   L10I, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V77VI, V82I, L89MG
 R229ZZR229FJ931386None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63ST, C67E, H69K, V82I, L89MG
 R371ZZR371FJ931409None   L10I, T12P, I13V, K14R, I15IV, K20I, E35Q, M36I, N37D, R41K, R57K, I64L, C67E, H69K, V82I, L89MG
 R361ZZR361FJ931418None  L33IV, Q58EL10I, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89MG
 R271ZZR271FJ931447None   L10I, T12K, I13V, K20I, M36I, R41K, C67N, H69K, V82I, L89MG
 R446ZZR446FJ931456None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89MG
Vercauteren (2009)pt21965087239GQ398828None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 pt16933183872866GQ399331None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 pt16673361359719GQ399357None   L10I, I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MG
 pt15653947926666GQ399459None   L10I, I13V, K14R, G17E, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MG
 pt10516943936421GQ399973None   L10I, I13V, K14KR, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MG
 pt10117148488973GQ400013None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MG
 pt8917905805562GQ400133None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, A71AV, L89MG
 pt6569075399293GQ400368None   I3L, L10I, I13V, K20I, E35D, M36I, R41K, H69K, V77VI, V82I, L89M, I93IVG
 pt316kEKHbx6iUFGQ400708None   L10I, I13V, K14R, Q18R, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89MG
Yebra (2009)SP55-329660SP55-329660EU255358None   L10I, I13V, G17E, K20I, M36I, C67NS, H69KR, L89MG
Bonura (2010)1145_1301145_130GU969517None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, I72IV, V82I, L89MG
Castelbranco (2010)090011A090011AHM357729None   L10I, I13V, K14R, G17E, K20I, M36I, R41K, C67N, H69K, K70R, L89MG
Knops (2010)Pat03Pat03GU991864None  Q58EL10I, I13V, I15IV, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 Pat12Pat12GU991873None   L10I, I13V, K20I, E35D, M36I, N37NI, R41K, I66IV, H69K, V82I, L89IG
Yebra (2010)13841603SP00138416FJ481666None   L10I, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89MG
Fokam (2011)CIRCB-12541CIRCB-12541JQ796143None   L10I, I13V, G16E, K20I, E35ED, M36I, R41K, C67HQ, H69K, L89MG
Hamers (2011)300441CP076300441HM119863None   I3V, L10I, G16A, M36I, N37D, R41K, K43R, D60N, Q61D, C67E, H69K, T74S, L89M, I93LG
 CP076301709CP076301709HQ993704None   L10I, T12P, I13V, K14R, I15V, G16X, K20I, E35N, M36I, R41K, I62IV, L63PS, C67E, H69K, V82I, L89MG
 CP076301716CP076301716HQ993709None   L10I, I13V, L19I, K20I, E21K, M36I, R41K, C67E, H69K, K70R, L89MG
 CP076303490CP076303490HQ993979None   L10I, I13V, K20I, E35Q, M36I, R41K, K45R, R57K, I64M, C67E, H69K, V82I, L89M, T91IG
 CP076305160CP076305160HQ994114None   L10I, I13V, K20I, E35Q, M36I, R41K, K45R, R57K, C67E, H69K, V82I, L89MG
 CP763A03288CP763A03288HQ994613None   L10I, I13V, L19P, K20I, M36I, R41K, L63V, E65D, C67Y, I72V, V82I, L89MG
Ajoge (2012)H18HP18HM854108None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89MG
 H35HP35HM854116None   L10I, I13V, K20I, E35Q, M36I, R41K, R57K, L63Q, C67E, H69K, V82I, L89MG
Caron (2012)Gab082026Gab082026JN704999None   L10I, I13V, K14R, K20I, E34Q, M36I, R41K, C67S, H69K, K70R, V77I, L89MG
Chamberland (2012)D351cTD351cTHQ267644None   L10I, I13V, I15V, L19I, K20I, L23X, M36I, R41K, I64M, C67N, H69K, I72IM, L89MG
De Gascun (2012)IRL03699IRL03699JN622320None   L10I, V11VA, I13V, K20I, E35Q, M36I, R41K, R57K, Q61N, L63P, C67E, H69K, V82I, L89MG
 IRL21201IRL21201JN622353None   L10I, I13V, K20I, E34ED, E35G, M36I, P39PS, R41K, C67F, H69K, P79D, L89MG
 IRL51036IRL51036JN622356None   L10I, T12TK, I13V, I15V, K20I, E35D, M36I, R41K, L63LV, G68GA, H69K, V82I, L89M, I93IV, L97L*G
Machado (2012)CUPL1020CUPL1020HQ655397None   L10I, I13V, I15V, K20I, E35D, M36I, R41K, C67N, H69K, V82I, L89MG
 CUPL1027CUPL1027HQ655404None  V11IL10I, I13V, K20I, M36I, N37S, R41K, I64M, H69K, V82I, L89M, I93LG
 CUPL1049CUPL1049JN000021None   L10I, T12A, I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 CUPL1070CUPL1070JN000042None   L10I, T12P, I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63P, C67H, H69K, L89MG
 CUPL1083CUPL1083JN000055None   L10I, I13V, K14R, I15V, L19I, K20I, E35D, M36I, L63P, H69K, L89M, T91V, I93LG
 CUPL1087CUPL1087JN000059None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MG
 CUPL1143CUPL1143JX194222None   L10I, T12K, I13V, K14R, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MG
 CUPL1144CUPL1144JX194223None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, C67N, H69K, V82I, L89MG
 CUPL1146CUPL1146JX194225None   L10I, I13V, K14R, K20I, L24V, E35D, M36I, R41K, L63I, H69K, K70R, I72T, V82I, L89MG
Avi (2013)359359JX431855None   L10I, I13V, K14R, G17E, K20I, E35D, M36I, R41K, L63H, C67G, H69K, K70R, I72T, V82I, L89MG
 366366JX431860None   L10I, I13V, K14R, G17E, K20I, E35D, M36I, R41K, L63H, H69K, V82I, L89MG
Frentz (2013)EHR-39409EHR-39409JX300208None   L10I, I13V, K14KR, K20I, E35N, M36I, R41K, I62IV, L63T, C67E, H69Q, I72T, V77I, V82I, L89MG
 EHR-45704EHR-45704JX300301None   L10I, T12TK, I13V, I15V, K20I, E35D, M36I, R41K, L63LV, G68GA, H69K, V82I, L89M, I93IV, L97L*G
 EHR-97422EHR-97422JX301141None   L10I, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89MG
Imade (2013)ZZRJ074ZZRJ074KC755263None   L10I, I13V, K14R, K20I, E35Q, M36I, N37D, R41RK, R57K, L63S, C67E, H69K, V82I, L89MG
 ZZRJ008ZZRJ008KC755240None   L10I, I13V, K14R, K20I, E35Q, M36I, R41K, K45R, R57K, L63PS, C67E, H69K, V82I, L89MG
Lunar (2013)6391-106391-10JX046402None   L10I, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, L63LP, C67E, H69K, K70KR, V82I, L89MG
Pircher (2013)A1003A1003JX110256None   L10I, T12TK, I13V, K14R, K20I, M36I, N37D, R41K, C67N, H69K, K70R, V82I, L89MG