<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype G
Gene PR
Mutation L10I
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 37
Isolates 43
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Holguin (2003)SP_LP17SP_LP17AF455614PINA  L10I, I13V, K14R, E35D, M36I, R41K, H69K, L89MG
Vergne (2003)VL01SN63HPD01SN63AJ583750IDV M46I, V82TL89VL10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69KG
Montes (2004)MB_patMAS D01_MASD709AJ577944NFV8  L10I, I13V, K14Q, L19P, K20I, M36I, R41K, L63P, C67Y, H69K, L89MG
 MB_patVIG02_VIG701AJ578178SQV, RTV, IDV252M46I, I54A, V82T L10I, I13V, K14R, K20I, E35N, M36I, N37D, R41K, Q61H, L63P, C67E, H69K, I72V, T74S, L89MG
Non-B Workgroup (2005)PL887561905AY900995IDV M46I, I54V, V82T, I84VQ58EL10I, I13V, K20I, E35D, M36I, R41K, L63P, I66F, H69K, A71AV, T74K, L89MG
 PL3679561171AY900999NFV L90M L10I, I13V, K14R, K20I, E35D, M36I, R41K, R57K, H69K, V82I, L89MG
 PL2647363176AY901007SQV, NFV, IDV, RTV, LPV I54V, V82F, L90ML89VL10I, I13V, K14R, K20I, E35N, M36I, N37ND, R41K, L63P, H69K, A71V, Q92QKG
  89488 SQV, NFV, IDV, RTV, LPV, UnknownNAM46I, I50V, I54V, V82F, L90ML89VL10I, I13A, K14R, K20IT, A22AV, E35N, M36I, N37D, R41K, L63P, I66V, C67CR, H69K, K70KT, A71V, I85IV, Q92KG
 PL3031563371AY901022IDV M46I, I54V, V82T, I84VL89VL10I, I13A, K14R, K20I, E35D, M36I, N37ND, R41K, L63LP, I66F, H69K, A71V, I85IMG
 PL3814564117AY901026SQV, IDV238M46I, I54V, V82T, I84V L10I, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63P, I66F, H69K, K70R, L89MG
 PL3832564508AY901035IDV87I54V, V82A L10I, I13V, K14KR, L19LS, K20I, E35D, M36I, N37D, R41K, H69K, A71IV, T74S, L89IG
 PL888465233AY901039SQV, IDV, LPV M46I, I54V, L76V, L90MF53L, L89VL10I, I13A, K14R, I15IV, K20I, E35D, M36I, R41K, Q61QH, L63P, H69K, A71IT, V82X, T91TSG
 PL1003066215AY901040SQV, IDV I54V, V82A, L90MF53LL10I, I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63P, C67CF, H69K, A71V, L89IG
 PL3419967194AY901053IDV   L10I, I13V, K14KR, K20I, E35D, M36I, R41K, R57K, H69K, V82I, L89MG
 PL1168468720AY901063IDV I54V, V82T, I84V, L90LML33LI, L89VL10I, I13A, K14KR, K20I, E35D, M36I, R41K, I66F, H69K, A71VG
 PL4074569862AY901093SQV, IDV, ATV   L10I, I13V, K14R, L19I, K20I, E34Q, E35ED, M36I, P39S, R41K, C67E, H69K, V77VI, L89MG
 TK2013TK2013 IDV, SQV, RTV, NFV196M46I, I54V, L90M L10I, I13V, I15V, K20I, E35D, M36I, N37D, R41K, R57K, Q61H, I66F, H69K, V82I, L89M, Q92KG
  TK2013a IDV, SQV, RTV, NFV196M46I, I54V, L90M L10I, I13V, I15V, K20I, E35D, M36I, N37D, R41K, R57K, Q61H, I66F, H69K, V82I, L89M, Q92KG
  TK2013b IDV, SQV, RTV, NFV, LPV, APV225M46I, I47V, I54V, L90M L10I, I13V, I15V, K20I, E35D, M36I, N37D, R41K, R57K, Q61H, I66F, H69K, V82I, L89IM, Q92KG
 PL1003066215 SQV, IDV275I54V, V82A, L90MF53LL10I, I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63P, C67CF, H69K, A71V, L89IG
 PL28120100793 LPV39M46MI, I54V, L76VL24LI, Q58EL10I, I13V, K20I, E35D, M36I, R41K, L63P, H69K, V82I, L89MG
 PL2909097083 IDV, NFV, SQV, RTV179M46L, G48V, I54V, V82T L10I, I13V, K14R, K20I, E35DN, M36V, R41Q, H69K, K70E, A71V, L89I, I93LG
 PL3373076228 Unknown, RTV, IDV>80I54V, V82F L10I, I13V, K14R, K20I, E35D, M36I, R41K, K45Q, H69K, L89MG
 PL3432698448 IDV, NFV180I54V, V82ML24I, Q58E, L89MVL10I, I13V, K14R, K20I, E35D, M36I, R41K, Q61N, L63T, H69KG
 PL40388105421 IDV190M46MI, I54V, V82T, I84VL89MVL10I, I13V, K14R, I15V, K20I, E35D, M36I, R41K, Q61QH, I62IV, L63LAPV, I66FL, H69K, A71AV, T74TSG
 PL4208372851 NFV, RTV, IDV214M46I, I54V, V82F, L90M L10I, I13V, K14R, I15IV, K20I, E35D, M36V, N37ND, R41K, R57RK, D60DE, L63LP, H69K, A71AV, L89IG
 PL4236173571 RTV, IDV160M46L, G48V, I54V, V82SK43TL10I, I13A, K14R, K20I, E35D, M36I, R41K, I62V, I66F, H69K, T74S, L89IG
 PL4366176757 IDV204  L10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, K70R, V82I, L89M, I93IVG
 PL4812187876 IDV, NFV234L90M L10I, I13V, K14R, L19I, K20IV, E35D, M36I, N37NT, R41K, I62V, I66F, H69K, A71V, V82I, Q92KG
 PL48170102151 IDV39  L10I, I13V, L19LP, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MG
 PL4935891289 IDV104  L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, K70KR, V82I, L89MG
 PL86570861 SQV420I54V, L90MRF53LL10I, I13V, K14R, K20I, E35D, M36I, R41K, D60DE, L63AP, H69K, A71V, V82I, L89IMG
  105515 SQV486I54V, L90MF53LL10I, I13V, K14KR, K20I, E35D, M36I, N37D, R41K, L63A, H69K, A71V, T74S, V82I, L89IG
Weber (2005)M64940M64940AY677452IDV, NFV, LPV293G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, A71VG
  M64940AY714453IDV, NFV195G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, K70KR, A71VG
Baxter (2006)48-12511251-30602DQ877776PINAM46I, I54V, V82T, I84V, L90ML89VL10I, I13V, K20I, E35D, M36I, N37D, R41K, K55N, I62V, L63P, C67F, H69K, A71V, T74SG
 48-12731273-30904DQ877793PINAM46I, I47V, I54V, V82T, I84VK43T, F53L, L89VL10I, I13A, K14R, K20V, A22V, M36I, N37D, R41K, L63P, I66V, H69K, A71V, T74S, T91TCSG
 48-31863186-30506DQ878094PINAM46L, I54V, V82A, I84VV11I, L24I, L89IVL10I, I13A, K14R, K20I, A22V, E35D, M36I, R41K, I62V, L63P, C67Y, H69K, A71V, T74S, Q92KG
 48-43944394-30912DQ878533PINAM46I, I54V, L76V, V82F L10I, I13V, G16GA, K20I, E35D, M36I, L63P, H69K, T74TS, L89MG
 48-80768076-30925DQ879086PINAM46I, I54V, L76V, I84VQ58EL10I, I13V, K14R, I15V, K20I, E35N, M36I, N37D, R57RK, D60Q, L63P, H69K, V82I, L89MG
Knops (2010)Pat08Pat08GU991869NFV, IDV, LPV M46I, I54A, V82M, L90MK43TT4A, L10I, I13V, I15V, L19P, K20I, E35S, M36I, N37E, R41K, V56A, R57K, L63P, H69K, A71V, T74S, V77I, L89I, Q92KG
 Pat14Pat14GU991875SQV, LPV M46L, G48V, I54V, V82S, L90MK43TL10I, T12K, I13V, I15V, K20I, E35N, M36I, N37D, R41K, Q61HN, L63C, C67W, H69K, T74S, L89IG
 Pat20Pat20GU991881IDV   L10I, I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MG

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