<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L89V
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 17
Isolates 17
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)9764497644AY365553PINAV32I, M46I, I47V, V82AL24I, L89VL10I, T12N, I15V, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, A71T, V77I, I93LF
 115855115855AY365925PINAM46ML, I54AV, I84V, L90MV11I, L89VL10I, I13V, G17E, K20V, E35D, M36I, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
Baxter (2006)48-32663266-30729DQ878171PINAM46I, I54V, V82AV11VI, L24I, L33F, L89VL10I, I15V, K20A, E35DN, M36L, N37Q, R41K, K55R, R57RK, D60E, Q61E, I62V, L63P, I64L, A71V, I72M, V77I, T91S, I93LF
Dumans (2009)RENA395RENA395FJ405051IDV, RTV200L76VL89VK20I, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, I93LF
 RENA626RENA626FJ405172IDV, SQV, RTV, NFV, LPV335M46L, I50V, I54V, V82T, L90MK43T, L89VL10I, T12N, I15V, L19P, K20R, E21Q, E35D, M36I, N37D, K55R, R57K, Q61N, L63P, A71V, I72V, I85V, Q92KF
Aulicino (2011)ARL589CJAARL589CJAFJ525811PINAM46L, I54V, L76V, V82F, L90ML33F, G73A, L89VL10V, I13V, K14R, I15V, G17E, K20T, E35N, M36I, R57K, Q61D, L63P, A71V, I93LF
 ARN567GMARN567GMFJ525862PINAI54M, V82M, L90MV11I, L33F, K43T, G73S, L89VL10I, I13V, K14R, I15V, G17E, K20T, E35N, M36I, R41K, R57K, Q61N, L63P, T74S, I93LF
Jones (2012)148707148707JN669719PINAI54V, V82A, L90ML33I, F53L, G73S, L89VL10I, I13V, K20R, E35D, M36I, K43E, K55R, R57K, D60K, Q61N, I62V, L63P, A71I, I72E, C95LF
 151726151726JN669766PINAI54A, I84V, L90MV11I, G73GDNS, L89VL10I, T12TP, I13V, G17E, K20V, E35D, M36I, N37NDEK, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
 157416157416JN669883PINAM46I, I50V, I54V, L76V, V82A, L90LMQ58E, L89VL10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, A71V, G73DE, I85V, Q92K, I93LF
 160560160560JN669981PINAM46I, I54V, L76V, L90ML89VL10V, I13V, I15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 163933163933JN670073PINAM46I, I47V, I54V, V82F, L90ML89VL10I, I15V, G17D, K20T, E35N, M36I, R41K, K55KR, R57K, Q61N, I62V, L63P, T74S, V77I, I85V, I93LF
 167774167774JN670161PINAV32I, I47V, I54M, N88S, L90LML33F, G73S, L89VT12I, I13V, I15V, G16E, K20R, E35ED, M36I, R41K, R57K, Q61N, G68GE, A71IV, I72T, V77VEF
 177288177288JN670432PINAM46I, I50V, I54A, V82A, L90ML33F, Q58E, L89VL10I, I13V, I15V, G16Q, K20R, E35N, M36I, P39Q, R41K, K55R, R57K, Q61N, L63P, A71V, I93ILF
 198666198666JN671128PINAM46I, I54V, V82AL24I, L89VI15V, G16E, K20M, E35D, M36I, R41K, K45R, R57K, Q61N, I72TF
 202350202350JN671269PINAM46L, I54A, V82AL89VL10I, T12I, I13V, I15V, G16A, L19P, K20L, E35D, M36I, N37ND, R41RK, K45KR, K55KR, R57K, Q61D, A71V, I72TF
 207306207306JN671430PINAM46L, I54V, V82AL24I, G48E, F53L, L89VL10I, I13IV, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, I64L, H69Y, A71V, Q92K, I93LF