<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L89V
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 25
Isolates 25
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)9764497644AY365553PINAV32I, M46I, I47V, V82AL24I, L89VL10I, T12N, I15V, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, A71T, V77I, I93LF
 115855115855AY365925PINAM46ML, I54AV, I84V, L90MV11I, L89VL10I, I13V, G17E, K20V, E35D, M36I, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
Baxter (2006)48-32663266-30729DQ878171PINAM46I, I54V, V82AV11VI, L24I, L33F, L89VL10I, I15V, K20A, E35DN, M36L, N37Q, R41K, K55R, R57RK, D60E, Q61E, I62V, L63P, I64L, A71V, I72M, V77I, T91S, I93LF
 48-92789278-30924DQ877616PINAM46I, I47V, I54L, V82A, L90MK43T, F53L, G73C, L89VL10V, I15V, G16E, Q18H, K20M, E34Q, M36I, P39S, K55R, D60E, I62V, L63P, I85VF
Cardoso (2009)3144BRGO3144FJ638464PINAM46I, I50V, I54V, L76V, V82AL89VL10I, I13V, G16E, K20R, M36I, N37ND, R41RK, K55R, D60E, Q61N, A71V, I72RF
Dumans (2009)RENA395RENA395FJ405051IDV, RTV200L76VL89VK20I, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, I93LF
 RENA626RENA626FJ405172IDV, SQV, RTV, NFV, LPV335M46L, I50V, I54V, V82T, L90MK43T, L89VL10I, T12N, I15V, L19P, K20R, E21Q, E35D, M36I, N37D, K55R, R57K, Q61N, L63P, A71V, I72V, I85V, Q92KF
Jones (2012)148707148707JN669719PINAI54V, V82A, L90ML33I, F53L, G73S, L89VL10I, I13V, K20R, E35D, M36I, K43E, K55R, R57K, D60K, Q61N, I62V, L63P, A71I, I72E, C95LF
 151726151726JN669766PINAI54A, I84V, L90MV11I, G73GDNS, L89VL10I, T12TP, I13V, G17E, K20V, E35D, M36I, N37NDEK, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
 160560160560JN669981PINAM46I, I54V, L76V, L90ML89VL10V, I13V, I15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 167774167774JN670161PINAV32I, I47V, I54M, N88S, L90LML33F, G73S, L89VT12I, I13V, I15V, G16E, K20R, E35ED, M36I, R41K, R57K, Q61N, G68GE, A71IV, I72T, V77VEF
 182090182090JN670599PINAM46I, I54V, L76VL89VK20P, E35N, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 198666198666JN671128PINAM46I, I54V, V82AL24I, L89VI15V, G16E, K20M, E35D, M36I, R41K, K45R, R57K, Q61N, I72TF
 202350202350JN671269PINAM46L, I54A, V82AL89VL10I, T12I, I13V, I15V, G16A, L19P, K20L, E35D, M36I, N37ND, R41RK, K45KR, K55KR, R57K, Q61D, A71V, I72TF
Diaz (2015)RenG17082RenG17082KT748110PINAM46I, I50L, V82A, L90ML10LF, L33F, F53L, L89VI13V, I15V, K20T, E35N, M36I, N37D, R41K, K43R, K55KR, R57K, Q61N, L63P, A71IV, Q92KF
 RenG16518RenG16518KT747546PINAM46I, I47V, I54V, V82A, L90MV11I, K43T, F53L, G73C, T74P, L89VL10V, T12K, I13A, I15V, L19I, K20I, E34Q, E35D, M36I, N37E, K55R, I62V, L63T, I72VF
 RenG16900RenG16900KT747928PINAM46I, I54VN88G, L89VL10I, I13V, I15V, K20T, E35D, M36I, N37ND, R41K, R57K, Q61N, L63P, I72T, V82IF
 RenG16634RenG16634KT747662PINAI54AV, V82AG73GA, L89VL10I, I13AV, K14KR, K20I, A22AV, E35D, M36I, N37DE, R41RK, R57K, Q61N, L63LP, A71V, I72T, T74S, I93LF
 RenG17015RenG17015KT748043PINAV32I, M46I, I47A, L90ML89VL10V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, L63P, A71V, Q92K, I93LF
 RenG17240RenG17240KT748268PINAV32I, M46I, I47V, I54M, L90ML33F, F53L, L89VL10I, I13V, I15V, L19V, K20R, E35D, M36I, N37DE, R41K, G51A, R57K, Q61N, I66F, A71V, G73N, V77I, V82IF
 RenG13805RenG13805KT744833PINAM46I, I47IV, L76VL10F, L33I, N83ND, L89VI13V, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63LP, I93ILF
 RenG13694RenG13694KT744722PINAV32I, I47V, G48V, I54V, V82A, L90ML33F, F53L, Q58E, L89VL10I, I13V, K14E, I15V, K20R, E34Q, E35D, M36I, N37D, R41K, K55R, V56I, R57K, D60E, I62V, L63P, A71V, I85V, Q92KF
 RenG12374RenG12374KT743402PINAV32I, M46I, I54L, I84V, L90ML33F, L89VL10V, L19I, K20R, E35D, M36I, N37D, R41K, K55N, R57K, Q61N, A71V, Q92KF
 RenG12253RenG12253KT743281PINAV32I, I54LK43T, F53L, L89VL10V, I13V, K20R, E34D, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, A71VF
 RenG11407RenG11407KT742435PINAV32I, I47AV11I, L89VI13V, K20T, E35D, M36I, R41K, F53I, R57K, Q61N, I62IV, A71V, I72TF