<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L89M
Rx >= 1 PI
IncludeMixtures No
References 31
Patients 239
Isolates 251
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Balotta (2000)CB-262CB-262AF252045SQV, IDV   G17E, E35D, M36I, R41K, R57K, Q61HP, I62V, L89MF
Brindeiro (2002)TVGG3TVGG3AY145819NFV30I54IV, V82VA L10LV, I15V, L19I, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, H69Y, I72T, L89MF
 TVSP21TVSP21AY900897RTV, IDV, NFV91  I15V, E35D, M36I, R41K, Q61N, K70R, I72T, L89MF
 TVSP22TVSP22AY145832Unknown, RTV, IDV, NFV>81  I15V, E35D, M36I, R41K, Q61N, K70R, I72T, L89MF
Gibb (2002)DMG8686_w25 NFV8  L10V, I13V, I15V, G16E, K20KR, E35D, M36I, R41K, R57K, L63T, E65D, I72IATV, L89MF
Apetrei (2003)AC_Pat1RO.00.IS.01AY333462IDV, UnknownNAM46I, I54V, V82AL24I, K43TL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.01AY333463IDV, Unknown, SQV, NFVNAM46I, I54V, V82A, I84VL24I, K43T, G48W, F53LL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat4RO.00.IS.04AY333484IDV, SQV, NFV   L10V, T12S, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat5RO.00.IS.05AY333471IDV M46I, I54V, V82A L10I, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, T74S, L89MF
 AC_Pat6RO.00.IS.06AY333525IDV, RTV, NFV   I15V, L19I, E35D, M36I, R41K, R57K, I62V, L63T, E65D, V82I, L89M, I93LF
  RO.01.IS.06AY333526IDV, RTV, NFV, UnknownNA  L10V, I15V, L19I, K20T, E35D, M36I, R41K, R57K, I62V, L63T, E65D, V82I, L89M, I93L, F99YF
 AC_Pat7RO.00.IS.07AY333458IDV, SQV, NFV, UnknownNAM46L, I54V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.07AY333459IDV, SQV, NFV, UnknownNAM46L, I54V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat20RO.00.IS.20AY333497IDV   I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.20AY333498IDV, RTV   I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat21RO.00.IS.21AY333455IDV   I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, L89MF
  RO.01.IS.21AY333456IDV   T12I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, L89MF
 AC_Pat22RO.00.IS.22AY333460IDV, RTV, NFV I54V, V82A L10V, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89MF
 AC_Pat23RO.00.IS.23AY333499IDV V82A I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.23AY333500IDV, SQV, NFV V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72T, L89MF
 AC_Pat24RO.00.IS.24AY333496IDV V82A L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, T74S, L89MF
 AC_Pat26RO.00.IS.26AY333486IDV   L10V, I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72V, T74S, L89MF
  RO.01.IS.26AY333487IDV, RTV M46I, I54V, V82T, I84V L10V, I15V, E35D, M36I, R41K, K55R, R57K, L63T, E65D, I72V, T74S, L89MF
 AC_Pat27RO.00.IS.27AY333516IDV   T12S, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63T, E65D, L89MF
  RO.01.IS.27AY333517IDV   T12S, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63T, E65D, L89MF
 AC_Pat28RO.00.IS.28AY333452IDV   I15V, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat29RO.00.IS.29AY333511IDV   T12S, I15V, G16E, K20R, E35D, M36I, R57K, L63T, E65D, I72T, L89MF
 AC_Pat30RO.00.IS.30AY333513IDV, RTV, SQV, NFV   T12S, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89M, Q92KF
 AC_Pat31RO.00.IS.31AY333518IDV   T12S, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, L89MF
  RO.01.IS.31AY333519IDV, SQV, NFV   T12S, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, L89MF
 AC_Pat32RO.00.IS.32AY333492IDV   L10I, I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M, I93LF
  RO.01.IS.32AY333493IDV, NFV   L10I, I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M, I93LF
 AC_Pat33RO.00.IS.33AY333477IDV   L10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72V, L89MF
  RO.01.IS.33AY333478IDV, NFV   L10V, I13V, I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72V, L89MF
 AC_Pat34RO.00.IS.34AY333521IDV   L10V, T12S, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89MF
 AC_Pat35RO.00.IS.35AY333491IDV   L10V, I15V, G16E, E35D, M36I, R41K, R57K, I62V, L63T, E65D, L89MF
 AC_Pat36RO.00.IS.36AY333461IDV, RTV, SQV, NFV M46L, I54V, V82A L10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, K70E, I72T, L89MF
 AC_Pat37RO.00.IS.37AY333488IDV, RTV L90M L10V, T12S, I15V, L19I, K20T, E35D, M36I, R41K, R57K, I62V, L63T, E65D, T74S, L89MF
 AC_Pat39RO.00.IS.39AY333501IDV   I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89MF
 AC_Pat40RO.00.IS.40AY333465IDV M46I, I54V, V82A L10V, I15V, G17E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat41RO.00.IS.41AY333507IDV   T12I, I15V, G16E, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat42RO.00.IS.42AY333520IDV25  L10V, T12S, I15V, L19V, K20R, E35D, M36I, R41K, R57K, I62V, L63T, L89M, I93LF
 AC_Pat43RO.00.IS.43AY333509IDV   T12N, I15V, G16E, K20R, E35D, M36I, R57K, I62V, L63T, E65D, I72T, L89MF
 AC_Pat45RO.00.IS.45AY333473IDV I54V, V82A L10V, I15V, K20R, L23V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat46RO.00.IS.46AY333454IDV, Unknown, SQV, NFVNA  I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat47RO.00.IS.47AY333457IDV   T12S, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, V82I, L89MF
de Sa Filho (2003)BREPM020BREPM020AY182788IDV M46I, I54V, V82AL24IL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L89MF
 BREPM022BREPM022AY182789IDV D30N, I84V L10I, G16E, P39S, K43R, R57K, Q61N, I64V, V77I, G86R, L89M, I93LF
 BREPM177BREPM177AY182829IDV   I15V, E35D, M36I, R41K, R57K, Q61N, E65D, L89MF
 BREPM105BREPM105AY182808IDV I54VV11IT4I, L10S, K14R, I15V, E35DN, M36I, R41K, R57K, Q61N, E65D, L89MF
Monno (2003)ML_Pat12ML_Pat12 PINA  I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72IT, L89MF
Shafer (2003)A384_40794079bEF549325NFV30N88SL33LFL10I, I15V, K20KT, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, L89MF
Soares (2003)BR1BR1AY275717SQV, IDV, LPV139  K14R, I15V, E35D, M36I, P39T, R41K, R57K, Q61N, L89MF
 BR60BR60AY275750IDV154M46I, I54V, V82TL24I, T74PL10I, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L89MF
Dumans (2004)RES093RES093AY390211IDV, RTV, Unknown>87I54V, V82AT, L90MF53LL10IV, K14R, I15V, G17D, L19I, K20R, E35D, M36I, R41K, D60E, Q61N, L63T, A71V, I72T, T74A, L89M, I93LF
 RG070RG070AY390210IDV, RTV, Unknown>178M46I, I54V, V82SL24I, F53FL, Q58EL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, A71V, L89M, I93LF
 F136F136AY390083NFV, Unknown>108  T12Q, I15V, E35D, M36I, R41K, R57K, Q61D, L63Q, K70T, V82I, L89MF
 RG008RG008AY390204IDV, RTV, Unknown>135  I15V, L19I, K20R, E35D, M36I, N37D, R41K, H69Q, L89M, I93LF
 RES12RES12AY390199SQV, RTV, NFV, Unknown>30  T12S, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L89MF
 RES077RES077AY390203SQV192L90MF53LL10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, T74S, L89MF
Gomez-Carrillo (2004)9858898588AY365578PINAM46L, V82AL24IL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, E65D, I72T, T74S, L89MF
 100502100502AY365613PINAI54V, V82A, L90M L10I, I15V, G17D, K20KR, E35D, M36I, R41K, K45R, R57K, Q61D, L63C, L89MF
 103519103519AY365681PINA  L10V, T12N, K14R, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, I72T, L89MF
 105436105436AY365727PINAM46L, I54V, L76V, V82AL23LIL10I, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63C, L89MF
 105506105506AY365729PINAN88S I15V, L19I, K20T, E35D, M36I, R41K, K45KR, R57K, Q61N, L89M, I93LF
 109559109559AY365823PINA  L10I, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63A, V82I, L89M, I93LF
 109590109590AY365824PINAD30NN83D, N88DL10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, I72R, L89MF
 115949115949AY365926PINAI54V, V82A L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63LP, T74S, L89MF
 120763120763AY365988PINAG48A, I54V, V82AL24I, F53LL10I, T12S, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, T74S, L89MF
 122744122744AY366015PINAM46I, I50V, I54V, V82AF53L, L76ML10I, I15V, K20R, E35D, M36I, R41K, K45R, K55R, R57K, Q61N, L63S, E65D, K70T, A71V, I72E, L89M, I93LF
 123442123442AY366022PINA  L10V, K14R, I15V, E35D, M36I, R41K, R57K, Q61N, L89M, I93LF
 126743126743AY366057PINAV32I, M46I, I47V, I54V, V82AL24I, L33F, F53LL10V, I15V, K20R, E34V, E35D, M36I, R41K, Q61N, I62V, L63P, T74S, L89M, Q92KF
Machado (2004)cs133cs133AY313342RTV155M46L, I54V, V82AL24IL10I, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, L89MF
Montes (2004)MB_patBAR99_BAR710AJ577733RTV, SQV, NFV176V82A K14Q, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, E65D, L89MF
  01_BAR714AJ577734RTV, SQV, NFV, APV, LPV273V82A L10I, K14Q, I15V, K20R, E35D, M36I, P39Q, R41K, R57K, Q61N, L63C, E65D, T74S, L89MF
Thomson (2004)99UFRJ_199UFRJ_1AY455778NFV39  E35D, M36I, R41K, R57K, D60E, Q61D, V77I, L89MF
 99UFRJ_999UFRJ_9AY455783IDV87D30N, M46L E21K, E34K, E35N, M36I, R41K, R57K, Q61H, L89MF
de Sa Filho (2005)BREPM108BREPM108AY771589PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L89M, I93LF
 BREPM119BREPM119AY771590PINA  T12E, I15V, E35D, M36I, R41K, R57K, D60E, Q61N, L89MF
 BREPM275BREPM275AY771592PINAD30NL33F, N88DL10V, T12K, I13V, I15V, K20T, E35D, M36L, N37E, K55R, R57K, D60E, Q61N, L63S, L89MF
Non-B Workgroup (2005)PL3749895930 IDV, LPV197  I15V, G17D, K20M, E35D, M36I, R57K, Q61H, L89MF
 PL4051769351 IDV, NFV241L90M L10I, I15V, G17D, K20T, E35D, M36I, R57K, Q61H, L63P, I64V, A71T, I72V, L89M, I93LF
 PL4840688662 APV104M46MI, I50IV, V82AL33FL10I, T12I, I13V, I15IV, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, G68E, I72R, L89MF
 PL4965792049 LPV8  I15V, G17E, K20R, E35D, M36I, R57K, Q61H, L63T, I72T, L89MF
Rodrigues (2005)BR0274502AY643151IDV202I54V, V82AL24IL10I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, T74S, L89MF
 BR01510700AY441820IDV, NFV, SQV, RTV161  K14R, I15V, G16E, E35D, M36I, R41K, G52K, R57K, D60E, Q61N, L63A, I72E, G86K, L89MF
 BR0181201AY643188RTV, NFV52M46MI, V82VA L10I, I15V, Q18L, K20KR, E35D, M36I, R41K, R57K, D60E, Q61N, L63T, C67X, H69Q, I72T, L89MF
 BR0208200AY441803NFV, SQV, RTV57  K14R, I15X, G16E, E35D, M36I, P39T, R41K, R57K, Q61N, L63V, L89MF
 BLF_Pat1BR03SP230AY643170IDV, Unknown>47  T12A, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63A, L89MF
 BLF_Pat2BR02SP158AY643139IDV, SQV, RTV153  L10I, I13V, Q18Y, E35D, M36I, R41K, R57K, Q61N, C67Y, K70R, L89MF
 BLF_Pat3BR02SP249AY643146Unknown, NFV>74N88S K20T, E35D, M36I, R41K, R57K, Q61N, V77I, L89MF
 BLF_Pat13BR03SP64AY643176NFV123N88S I15V, G16GE, L19I, K20T, E35D, M36I, N37NT, P39HQ, R41K, R57K, Q61D, I62IV, E65D, L89MF
 BLF_Pat14BR02SP108AY643134SQV, IDV194  I15V, E35ED, M36I, R41K, R57RK, Q61N, I62V, L63LP, I72IV, T74S, L89MF
 BLF_Pat20BR03SP220AY643168Unknown, NFV>173  L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63LP, E65D, T74S, L89MF
 BLF_Pat22BR03SP87AY643178RTV, NFV, APV217M46L, I54V, V82AL24I, Q58EL10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P, T74A, L89MF
 BLF_Pat23BR03SP224AY643169Unknown, RTV, APV>4M46MI, I50V, I54V, V82A, L90ML23I, F53L, L76ML10I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, I64M, L89M, I93LF
 BLF_Pat25BR02SP184AY643140NFV113L90M L10V, I15V, K20R, E35D, M36I, P39Q, R41K, R57K, Q61N, I62V, L63A, T74S, L89MF
 BLF_Pat27BR03SP155AY643163NFV35N88S L10V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, E65D, L89MF
 BLF_Pat28BR02SP258AY643148NFV71M46ML, N88NS, L90LM G17E, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, E65D, L89MF
 BLF_Pat29BR03SP247AY643171Unknown, NFV, SQV, RTV>88I54V, V82AN83DL10I, I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, I72T, L89M, I93LF
 BLF_Pat30BR03SP179AY643165IDV, RTV, Unknown, APV, LPV, NFV>152  L10V, I13IV, E35D, M36I, R41K, R57K, D60E, Q61N, I72IT, V77I, L89MF
 BLF_Pat31BR03SP35AY643173NFV, RTV33  T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63V, V82I, L89MF
 BLF_Pat32BR02SP56AY643153NFV, IDV, Unknown>294V82L, L90MK43TL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, L89M, I93LF
 BLF_Pat33BR03SP36AY643174SQV, NFV, IDV129M46LL10F, N88TK14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61N, I72V, L89MF
 BLF_Pat37BR03SP90AY643179IDV, RTV, SQV, Unknown, LPV>131  I15V, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, E65D, I72T, L89MF
 BLF_Pat38BR03SP211AY643167IDV, RTV52  L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, H69Y, I72T, L89MF
 BLF_Pat39BR02SP241AY643145IDV, NFV141N88S L10V, I15V, K20T, E35D, M36I, R57K, Q61D, I72R, L89M, I93LF
 BLF_Pat40BR02SP226AY643142NFV148N88S L10I, I13V, I15IV, K20T, E35D, M36I, R41K, R57K, Q61N, E65D, V77I, L89MF
 BLF_Pat42BR02SP154AY643138RTV, Unknown, NFV>70L90M T12R, I15V, L19S, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, T74S, V77I, L89M, I93ILF
Weber (2005)F62040F62040AY677410NFV114  L10V, T12X, I15V, K20R, E35D, M36I, R41K, R57K, D60E, I62V, L63T, L89MF
Baxter (2006)48-11921192-30929DQ877270PINAM46I, I50IV, I54V, L76LV, V82AL33LF, Q58EL10IV, G16GE, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63T, E65D, I72T, L89MF
 48-10191019-30619DQ877325PINAG48V, I54V, V82AF53LL10I, I15V, K20R, E35D, M36I, R41K, Q61N, I62IV, L63S, I64L, I72T, T74S, L89M, I93LF
 48-10741074-30626DQ877334PINAV32I, M46I, I47V, I54V, V82A, L90LML24I, L33F, T74PSL10I, I13IV, I15IV, G16E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63S, E65D, A71AV, V77I, L89M, Q92QK, I93LF
 48-10951095-30728DQ877347PINA N83NDI15V, K20R, E35D, M36I, R41K, R57K, Q61N, G68E, L89MF
 48-10271027-30707DQ877408PINAV32I, M46I, I47V, I54V, V82AL24I, L33F, F53LL10V, I15V, K20R, E34V, E35D, M36I, R41K, Q61N, I62V, L63P, T74S, L89M, Q92KF
 48-12061206-30604DQ877750PINAM46L, I50V, I54V, V82AL24I, L33F, Q58EL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, H69Y, L89MF
 48-12711271-30923DQ877792PINAG48V, I54V, V82SL24I, L33F, Q58EL10I, I15V, G16E, K20R, E34Q, E35D, M36I, P39PT, R41K, R57K, I62V, L63T, E65D, I72T, L89MF
 48-26142614-30624DQ877904PINAM46L, I54V, V82AL33F, F53LL10V, T12I, I15V, G16E, L19V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, I85V, L89MF
 48-30433043-30305DQ877955PINAM46I, G48M, I54V, L76V, V82A, L90MK43T, F53LT4S, L10V, K14Q, I15V, G16E, L19I, K20R, E35D, M36V, P39S, K55R, R57K, Q61N, I62V, L63T, E65H, H69R, I72V, T74S, L89M, C95CSF
 48-60236023-30403DQ878622PINAG48M, I54V, V82AL24I, K43KT, F53LL10I, I15V, Q18E, K20R, E35D, M36I, N37NK, R41K, R57K, Q61N, E65D, T74S, L89MF
 48-61196119-30924DQ878705PINAM46L, I54V, V82AL24IL10V, T12P, G17D, K20R, E35D, M36I, R57K, Q61N, L63S, I72T, L89MF
 48-61786178-30731DQ878750PINAM46MI, G48GV, I50V, I54V, V82TL33FL10V, I15V, K20R, E35D, M36I, P39PQ, R41K, R57K, Q61N, L63P, T74S, L89M, I93ILF
 48-92899289-30930DQ877308PINAM46L, I54V, V82A, I84IVL24I, L33LFL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63LP, A71V, L89M, Q92K, I93LF
 48-92669266-30915DQ877516PINAM46L, I54V, L76V, V82A, L90M L10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, H69R, K70R, A71V, I72IV, L89M, I93LF
 48-92509250-30908DQ877602PINAM46L, I54V, V82AV11VI, L24I, L33F, T74PL10I, I13V, G17E, L19I, K20R, E35D, M36I, R41K, R57K, Q61DN, I62V, L63T, E65D, I72T, L89MF
 48-90929092-30827DQ877655PINAM46I, I54V, V82A, L90MK43T, F53FLL10I, K20R, E35D, M36I, R41K, K55KR, R57K, Q61D, I62V, L63T, E65ED, I72T, T74TS, L89MF
 48-91519151-30826DQ877716PINAM46FL, I54V, V82A, L90M L10I, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, D60E, Q61N, L63P, H69Y, A71V, I72T, V77I, L89M, I93LF
Sanabani (2006)01BR08701BR087DQ358801PINAM46L, V82A I15V, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L89MF
 01BR12501BR125DQ358802PINA  K14R, I15V, E35D, M36I, R41K, R57K, Q61N, L89MF
 01BR22601BR226DQ358803PINA  L10I, T12K, K14N, I15V, E35D, M36I, R41K, R57K, Q61N, E65D, L89MF
 01BR32301BR323DQ358804PINA  L10V, E35D, M36I, R41K, R57K, D60E, Q61D, L63S, L89MF
 02BR03302BR033DQ358811PINAI54V, V82A, L90M L10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, L89M, I93LF
 02BR03402BR034DQ358812PINAL90M G16E, K20M, E35D, M36V, R41K, K43R, R57K, Q61N, L89MF
Santos (2006)118118PRAY275778SQV, IDV, RTV, APV, LPV287G48V, I50V, I54S, V82AL33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37D, Q61N, L63T, I85V, L89MF
 123123PRAY275779IDV291  I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L89MF
 135135PRAY275781IDV, Unknown, RTV>163I54V, V82AQ58EL10V, K14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, L89MF
 FB109FB109DQ191035SQV, RTV, IDV214I54V, V82A L10V, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, L89MF
Eyer-Silva (2007)BRSAP0704BRSAP07DQ899704LPV22  I15V, E35D, M36I, N37D, R41K, R57K, Q61N, L63V, I64M, L89MF
Rios (2007)CH2MR_CH2EF193885Unknown, IDVNA  T12K, I15V, E35D, M36I, R41K, R57K, Q61S, C67W, V82I, L89MF
von Wyl (2007)1091789954EF449996PINAD30N I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, I62V, L63I, I64M, I72V, L89MF
 81496899EF450023PINAN88S L10V, I15V, K20R, E35D, M36I, R41K, I62V, H69Q, L89MF
Cardoso (2009)3020BRGO3020FJ638423PINA  E35D, M36I, R41K, R57K, Q61N, L63P, L89MF
 3062BRGO3062FJ638432PINAI50L T12I, I13V, E35D, M36I, P39Q, R41K, R57K, Q61N, L63P, K70R, L89MF
 3082BRGO3082FJ638437PINA  T12I, I13V, E35D, M36I, R41K, R57K, Q61N, L63LP, L89MF
Dumans (2009)RENA101RENA101FJ405038NFV78 N88DV11VF, I15V, K20T, E35D, M36I, R41K, R57K, Q61D, I72V, V77I, L89MF
 RENA389RENA389FJ405040NFV30  E35D, M36I, R41K, K45R, R57K, Q61N, L63P, V77I, L89M, I93LF
 RES303_03RES303_03FJ405041RTV, Unknown>157I54V, V82A L10I, K14R, I15V, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, T74A, L89MF
 RENA578RENA578FJ405042IDV, SQV, RTV, NFV, LPV335M46I, I54A, V82AL24I, L33F, Q58EL10I, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63A, L89MF
 RENA686RENA686FJ405043IDV, NFV326M46I, I54V, V82AL24I, K43T, T74PL10I, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63C, E65D, L89MF
 RENA361RENA361FJ405045IDV, Unknown, SQV, RTV, NFV>174  L10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, E65D, I72T, L89M, I93LF
 RENA432RENA432FJ405047SQV, RTV, IDV, APV, LPV326N88S I15V, K20T, E35D, M36I, R41K, R57K, Q61N, H69Y, I72T, L89MF
 RENA251RENA251FJ405048NFV161N88S L10V, T12K, I13V, K14E, I15V, G16E, K20T, E35D, M36I, R41K, Q61N, E65R, L89MF
 RES327_03RES327_03FJ405050RTV, NFV100  I13V, E35D, M36I, R41K, R57K, D60E, Q61E, L63P, V77I, L89MF
 RES207_03RES207_03FJ405052IDV70  E35D, M36I, R41K, R57K, Q61N, L89MF
 117PR117PRFJ405058IDV, RTV, LPV182  E35D, M36I, P39Q, R41K, R57K, D60E, Q61D, I62V, L63P, L89MF
 RENA162RENA162FJ405125SQV, NFV, IDV260  L10I, E35D, M36I, R41K, D60E, Q61N, I62V, L63T, C67D, T74S, V77I, L89MF
 RENA483RENA483FJ405128IDV, NFV235  K14R, E35D, M36I, R41K, R57K, Q61N, L63P, L89M, Q92KF
 RENA463RENA463FJ405129NFV213L90M I13V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, T74S, L89M, I93ILF
 RENA596RENA596FJ405130IDV, Unknown, NFV, LPV>322M46L, I54V, V82A L10V, I15V, E35D, M36I, R41K, R57K, Q61N, I72T, L89MF
 RENA362RENA362FJ405143NFV, RTV, IDV65  I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, E65D, I72T, L89MF
 RENA456RENA456FJ405145NFV152  L10V, I13V, I15V, K20R, M36I, R41K, R57K, Q61N, L89MF
 RENA511RENA511FJ405146RTV, IDV, Unknown>61N88S L10V, I13V, I15V, K20R, E35D, M36I, N37T, R41K, K45R, R57K, Q61N, I62V, E65D, I72V, L89MF
 RENA254RENA254FJ405147IDV, NFV, Unknown>100V82A L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, T74S, L89MF
 RENA502RENA502FJ405148IDV, SQV, RTV, NFV244M46L, V82A L10V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, L89MF
 RENA410RENA410FJ405149NFV, Unknown>39  I13V, I15V, E35D, M36I, R41K, R57K, Q61N, L89MF
 RENA248RENA248FJ405150SQV, RTV, NFV113  I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72S, L89MF
 RENA749RENA749FJ405151Unknown, RTV, NFV, IDV>212  L10I, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, Q61N, I62V, L63P, I64M, H69Q, L89MF
 RENA313RENA313FJ405152IDV, RTV, LPV21  T12S, I15V, E35D, M36I, R41K, Q61N, L89MF
 RES314_03RES314_03FJ405155SQV226L90MF53LL10V, I15V, Q18E, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, L89MF
 RES28_02RES28_02FJ405158IDV, NFV, RTV, APV139M46L, I54V, V82AL33FL10I, G17D, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, L89MF
 75PR75PRFJ405164NFV104G48V, I54A, V82TK43TL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, L63E, E65D, I72V, L89M, I93LF
 59PR59PRFJ405165Unknown, NFV>27M46L, I54V, V82AL24IL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, I85V, L89MF
 RENA569RENA569FJ405166Unknown, NFV, RTV, IDV, APV>136  L10V, T12M, I15A, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, L89MF
 RENA651RENA651FJ405167RTV, IDV300M46L, I54V, V82A L10V, T12I, I13V, I15V, G16E, K20R, N37S, R57K, Q61N, L63S, E65D, L89MF
 RENA272RENA272FJ405168Unknown, IDV, RTV>256  I15V, G17E, E35D, M36I, R41K, R57K, Q61N, L63P, I72V, L89MF
 RENA446RENA446FJ405169RTV, NFV, Unknown, APV, SQV>205I54V, V82A, I84IV L10I, G17D, L19I, K20R, E35D, M36I, K55R, Q61D, L63T, E65D, I72T, T74S, L89MF
 RENA140RENA140FJ405170NFV91D30NN88DL10I, I13V, I15V, E35D, M36I, R41K, R57K, Q61D, L63C, K70R, I72T, L89MF
 RENA780RENA780FJ405171IDV200I54V, V82AK43TL10I, K14R, I15V, K20R, E35D, M36I, N37H, R41K, R57K, Q61D, L63P, L89M, I93ILF
 RENA166RENA166FJ405176RTV, NFV, SQV, APV, IDV173  L10V, I15V, G16E, E35D, M36I, P39T, R41K, R57K, Q61N, L63V, I72T, L89MF
 RENA332RENA332FJ405177IDV, SQV, RTV, NFV291I84V, L90M L10V, K20R, E35D, M36I, R41K, D60E, Q61D, I62V, L63P, H69Y, I72T, L89MF
 RENA818RENA818FJ405185Unknown, IDV>122  T12M, I15V, L19S, E35D, M36I, R57K, Q61N, L89MF
Sanabani (2009)8202BR082FJ771006PINA  I3V, L10P, T12A, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, L89MF
 57906BR579FJ771009PINA  L10P, G16E, E35D, M36I, R41K, D60E, Q61N, I62V, V77I, L89MF
 84407BR844FJ771010PINA  L10G, K14R, I15V, G17E, K20T, E35D, M36I, R57K, Q61N, E65D, L89MF
Thomson (2009)SP_B_059RU_SP_B_059FJ009814IDV, Unknown, LPV>8  G17GE, K20R, E35D, M36I, R41K, R57K, L89MF
Sanabani (2010)56106BR_FPS561HM026455PINA  I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, L89MF
 62507BR_FPS625HM026456PINA  I15V, K20R, E35D, M36I, R41K, R57K, Q61D, L89MF
 74207BR_FPS742HM026457PINA  T12A, I15V, E35D, M36I, R41K, R57K, Q61N, I72V, L89MF
 78307BR_FPS783HM026458PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L89M, I93LF
Aulicino (2011)ARL388RAEARL388RAEFJ525819PINA  L10I, T12I, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, L89M, I93LF
 ARM36WMRARM36WMRFJ525826PINAM46I, I47V, I54V, V82AL24I, K43T, F53LL10V, G16X, K20R, E35D, M36I, K55R, R57K, Q61N, L63T, H69R, T74S, L89MF
 ARN429AEDARN429AEDFJ525860PINAD30NN88DL10V, I15V, E35D, M36I, R41K, R57K, Q61D, L63P, V75I, L89M, I93LF
 3449-M959LPF3449-M959LPFHQ158155PINA  E35D, M36I, R41K, R57K, Q61N, L89M, I93LF
 3121-O269FJN3121-O269FJNHQ158163PINA  T12E, K14R, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, I72S, L89MF
Jones (2012)130299130299JN669482PINA  I15V, E35D, M36I, R57K, Q61D, I72T, L89M, I93LF
 143027143027JN669634PINAG48A, I54V, V82AL24I, F53LL10I, T12S, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, T74S, L89MF
 143481143481JN669641PINAM46MI, I54V, V82ATL24LIL10IV, I15V, K20R, E35D, M36I, N37E, R41K, R57K, Q61D, I62IV, L63PT, T74TS, L89M, I93LF
 146046146046JN669668PINAM46L, I54L, V82A, L90ML33FL10I, T12EQ, I15V, G16E, K20R, E34V, E35D, M36I, P39S, R41K, K55R, R57K, Q61N, I62V, L63T, A71V, I72T, T74S, L89M, I93LF
 146813146813JN669682PINAI54V, V82A, L90M L10I, T12TP, I15V, Q18K, K20M, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, T74A, V75VA, L89MF
 149643149643JN669739PINA  I15V, L19Q, E35D, M36I, R41K, R57K, Q61S, V77VI, L89MF
 152344152344JN669778PINA  I15V, E35D, M36I, P39Q, R41K, R57K, D60E, Q61D, I62V, L89MF
 153258153258JN669797PINA  I15IV, L19LI, E35D, M36I, R41K, R57K, Q61GS, L89MF
 154417154417JN669820PINAV32VI, I47A I15V, E35D, M36I, R41K, R57K, Q61N, L89M, I93LF
 155191155191JN669834PINAI54V, V82A L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, L89MF
 155565155565JN669843PINAM46MI, I54V, V82ASL24I, G48GRL10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63LDHV, I72T, T74S, L89MF
 156594156594JN669867PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K14R, Q18E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63T, E65D, A71V, L89M, I93LF
 157578157578JN669892PINAD30N, I54VN88DK14R, G17E, K20R, E35D, M36V, N37E, R41K, K43R, R57K, Q61N, L63T, E65D, H69Y, I72T, T74S, L89MF
 157709157709JN669896PINAM46I, I54V, L76V, V82AL33F, K43KTL10I, I15IV, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63T, H69Y, I72T, L89M, I93LF
 157978157978JN669905PINAI54V, V82AK43TL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63C, I64L, L89M, I93LF
 158844158844JN669935PINAM46I, I47V, I54V, V82SL23I, K43T, F53LL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63A, A71V, I72V, T74S, L89M, I93LF
 159022159022JN669939PINA  L10V, I15V, E35D, M36I, R41K, R57K, Q61N, E65D, I72T, L89MF
 159110159110JN669944PINAI54V, V82ML24I, K43TL10I, I15V, L19Q, K20R, E35D, M36V, R41K, R57K, Q61N, I62V, L63P, T74S, L89M, Q92KF
 160595160595JN669984PINAM46L, I54V, V82A, L90MQ58EL10V, I15V, K20R, E35D, M36I, Q61N, I62IV, L63P, I72V, R87RK, L89M, Q92KF
 161428161428JN670007PINAM46L, I54V, V82AL24LI, L33LF, K43KTL10V, T12K, K14I, I15V, G16E, L19P, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63C, E65D, A71AV, L89M, Q92K, I93ILF
 165415165415JN670100PINA  I15V, E35D, M36I, R41K, I62V, L63A, E65D, T74TS, L89MF
 166999166999JN670141PINAI47A, I84V I15V, E35D, M36I, R41K, R57K, Q61N, A71AV, L89M, I93LF
 169479169479JN670200PINA  E35D, M36I, R41K, K45R, R57K, Q61N, I72E, L89MF
 171303171303JN670253PINA  L10V, I15V, G16E, E35D, M36I, P39S, R41K, Q61N, I72R, L89MF
 171337171337JN670256PINAM46I, I54V, L76V, V82A L10V, I15V, K20R, M36I, R41K, R57K, Q61N, L63T, E65D, I72T, L89M, I93LF
 173048173048JN670311PINA  I15V, G17D, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, E65D, I72IV, L89MF
 175336175336JN670353PINAD30NN88DI13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63V, I64L, I72E, T74S, L89M, I93LF
 177830177830JN670459PINAL90M I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, I72R, L89MF
 178103178103JN670470PINA  L10V, T12K, I13V, G16E, L19LP, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63V, E65ED, I72T, L89MF
 178128178128JN670472PINA  I15V, L19Q, E35D, M36I, R41K, R57K, Q61NS, E65ED, L89MF
 178310178310JN670480PINA  I15V, E35D, M36I, N37D, R41K, R57K, D60E, Q61D, L89MF
 179773179773JN670525PINAM46I, I54A, V82A, L90MT74PL10I, I15V, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, I62V, L63V, A71V, L89M, I93LF
 180910180910JN670559PINA  T12S, I15V, L19I, E35D, M36I, R41K, R57K, Q61D, E65D, I72T, L89MF
 184896184896JN670689PINAM46I, I54V, V82T, I84V, L90ML33F, Q58EL10V, I13V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P, A71V, I85V, L89M, I93LF
 185656185656JN670706PINAD30DN, M46MI, N88NDGS L10V, I15V, G16E, K20R, E35D, M36I, P39PLS, R41RK, R57K, Q61N, I72V, L89M, I93LF
 189264189264JN670769PINA  I15V, E35D, M36I, N37D, R41K, R57K, Q61N, H69Y, I72T, L89MF
 189708189708JN670780PINAV32VI, M46I, I47IV, I54V, V82AF53FLL10I, I15V, G16GE, K20R, E35D, M36I, R41K, R57K, Q61N, L63Q, I64ILM, L89M, Q92QK, I93LF
 191048191048JN670808PINAM46I, I50V, I54V, V82AL33FL10V, K14KR, I15V, G16GE, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, I72V, T74S, L89MF
 192047192047JN670844PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, G16E, K20R, E35D, M36I, R41RK, K55R, R57K, D60E, Q61N, I62IV, L63C, E65ED, L89MF
 192661192661JN670862PINAI54V, V82AQ58EL10V, I15V, K20R, D25DG, E35D, M36I, R41K, R57K, Q61N, T74A, L89MF
 193819193819JN670911PINA  L10LV, K14KR, I15IV, E35D, M36I, R41K, R57K, Q61N, L63LI, I72V, L89MF
 194830194830JN670953PINAM46ML, I54IV, V82VA L10V, T12TA, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, L63P, L89MF
 194888194888JN670955PINAM46I, I47IV, I54V, L76V, V82AK43T, Q58QEL10IV, I15V, Q18E, L19LI, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61N, I62V, L63P, A71AV, L89M, I93ILF
 195201195201JN670970PINAD30N, I54VI47ML10I, K20T, E35N, M36I, N37D, K45A, V56A, R57K, Q61N, I62V, L63P, V77I, V82I, N88E, L89MF
 195689195689JN670995PINA  I15V, G16E, Q18K, K20M, E35D, M36I, R41K, R57K, Q61S, T74A, L89MF
 196628196628JN671029PINAV32I, M46I, I54V, V82C, L90M L10I, Q18E, K20R, E21EG, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, I72T, T74S, L89M, I93LF
 197101197101JN671057PINA  T12TA, E35D, M36I, R41K, K43KR, R57K, Q61N, I72T, L89MF
 197265197265JN671068PINA  T12A, K14R, I15V, G16E, Q18L, K20M, E35D, M36I, R41K, R57K, Q61N, I72T, L89MF
 198031198031JN671097PINA  I13IV, I15IV, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I72T, L89M, Q92RF
 202293202293JN671265PINAM46L, I54V, V82AL24IL10I, I15V, K20R, E35D, M36I, N37E, R41K, R57K, Q61D, I62IV, L63T, T74TS, L89MF
 204754204754JN671350PINAM46I, I50V, I54V, V82AL33F, Q58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, L89MF
 206020206020JN671383PINAI54V, V82TL33I, K43TI13V, I15V, K20R, E35D, M36I, N37D, R57K, Q61D, L63C, T74A, L89MF
 206165206165JN671393PINAM46L, I54V, I84VL24I, K43T, F53LL10I, I15V, G17D, K20T, E35N, M36I, K55R, Q61N, L63T, E65D, A71V, I72T, T74E, V82I, L89M, I93LF
 207469207469JN671434PINA  I15V, Q18L, E35D, M36I, R41K, K45R, R57K, Q61N, I72T, L89MF
 207575207575JN671439PINAM46MI, I50VL33FK14S, I15V, K20KT, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, T74A, I85IV, L89MF
 207640207640JN671442PINAM46L, G48AEKT, I54V, V82M, I84VL24I, L33I, K43T, F53FLL10I, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63IT, E65D, I72T, T74S, P79PS, L89MF
Grossman (2014)991991KF135177RTV, LPV52  I15V, L19I, E35D, M36I, P39Q, R41K, R57K, D60E, Q61D, L63S, L89MF