<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L89I
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 110
Isolates 110
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Brindeiro (2002)TVGG27TVGG27AY145828RTV, NFV30I54V, V82A, L90M L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89IF
de Sa Filho (2003)BREPM132BREPM132AY182818IDV I54V, V82A L33V, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, G68E, L89IF
Gomez-Carrillo (2004)113812113812AY365885PINAM46L, I54V, V82A L10LV, I15V, K20KR, E35D, M36I, R41K, R57K, Q61D, I62V, A71AV, L89I, I93LF
Machado (2004)cs189cs189AY313357NFV48L90M I15V, K20T, E35D, M36I, N37D, P39Q, R41K, R57K, D60E, Q61D, L89IF
Machado (2004)CS172proCS172proAY502095Unknown, NFV>21M46LN83DG16E, M36L, N37K, R41K, R57K, Q61D, I72R, L89IF
Non-B Workgroup (2005)BR38BR38AY900880NFV50L90M I15V, K20T, E35D, M36I, N37D, P39Q, R41K, R57K, D60E, Q61D, L89IF
 PL23900101500 Unknown, LPV>58I54V, V82AL33F, N83DL10V, I13V, K20R, E35D, M36I, R41K, R57K, I62V, T74S, L89IF
 PL36995591 Unknown, LPV>112M46L, G48V, I54V, V82A, L90ML33F, K43TL10V, I15V, G16E, K20M, E35N, M36I, N37ND, R57K, Q61D, G68E, H69R, A71T, I72R, L89I, I93LF
Rodrigues (2005)BLF_Pat5BR03SP147AY643162Unknown, IDV>256I54V, V82A L10I, I13V, I15V, G17E, K20I, E35D, M36I, R41K, R57K, Q61N, L63R, E65D, T74S, L89IF
 BLF_Pat8BR03SP01AY643156Unknown, RTV, IDV>51M46L, I54A, V82AL24I, K43TL10I, I15V, L19I, K20R, E35D, M36I, K55R, R57K, Q61N, L63P, A71V, I85V, L89IF
 BLF_Pat11BR03SP43AY643175IDV, Unknown, SQV, RTV, NFV>246I54V, V82A, L90M T12M, I15V, L19I, K20R, E35D, M36I, N37D, R41K, R57K, Q61H, I62V, H69R, T74S, L89I, C95CFF
 BLF_Pat17BR02SP88AY643155SQV, IDV, RTV, NFV, LPV285M46L, I50V, I54V, V82T, L90MK43TL10I, T12N, I15V, L19P, K20R, E21Q, E35D, M36I, N37D, K55R, R57K, Q61N, L63P, A71V, I72V, I85V, L89I, Q92KF
 BLF_Pat21BR02SP235AY643144IDV, Unknown>165I54V, V82A, L90M L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, A71V, I72T, L89I, Q92K, I93LF
 BLF_Pat34BR02SP220AY643141NFV111L90M K20RT, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89I, I93LF
 BLF_Pat35BR03SP71AY643177IDV, NFV269I54V, L90M L10V, I13V, I15V, K20T, E35D, M36I, N37T, R41K, R57K, Q61N, A71T, T74S, L89IF
Baxter (2006)48-32703270-30703DQ878175PINAM46L, I54V, V82A, L90MF53FLL10I, I15V, K20R, E35D, M36I, N37E, K55R, R57K, I62V, L63A, A71V, L89I, I93LF
 48-62856285-30924DQ878833PINAI54V, V82T, I84V T4TS, L10V, I13V, I15V, Q18M, L19Q, K20R, E35D, M36I, N37D, R41K, Q61N, A71V, L89IF
 48-92729272-30922DQ877288PINAM46L, I54V, V82A, L90LM L10I, I15V, L19Q, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, T74A, L89I, I93LF
 48-93499349-30923DQ877289PINAV32I, M46I, I47V, G48M, I54M, V82AL33F, F53LL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, T74S, L89IF
 48-91869186-30901DQ877291PINAM46L, I54V, V82AL24I, L33F, K43T, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I64L, A71V, I72T, L89I, I93LF
 48-90259025-30825DQ877501PINAM46I, I54S, V82AL33FL10I, I13V, I15V, K20M, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, T74S, L89IF
 48-91969196-30903DQ877572PINAM46I, I50V, I54V, V82AL33I, L76M, N83DL10V, T12E, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I72T, T74S, L89IF
Dumans (2009)RENA181RENA181FJ405173IDV213M46L, I54V, V82AL24IL10I, I15V, E35D, M36I, P39T, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71V, L89I, I93LF
 RENA390RENA390FJ405175NFV205L90M I13V, I15V, K20R, E35D, M36I, N37E, P39Q, R41K, R57K, Q61N, I62V, L63P, T74S, L89I, I93LF
Sanabani (2010)81207BR_FPS812HM026460PINA  I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, L89IF
Aulicino (2011)ARL622bisBCNARL622bisBCNFJ525815PINAI54V, V82AN83DL10V, I15V, G16E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I72R, L89I, I93LF
 ARN815QLSARN815QLSFJ525866PINAI54V, L90M I13V, I15V, K20T, E35D, M36I, P39Q, R57K, Q61N, L63P, A71T, V82I, L89I, Q92K, I93LF
 96-N422ELE96-N422ELEHQ158177PINA  T12D, I15V, L19I, K20R, M36I, R41K, K55R, R57K, Q61D, I72T, L89IF
Jones (2012)130315130315JN669484PINAL90M L10I, I13V, I15V, E35D, M36I, R41K, R57K, Q61N, L89IF
 130542130542JN669493PINAI54V, V82A, I84VF53LT4TS, L10V, T12E, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, A71V, T74S, I85V, L89IF
 132888132888JN669516PINAM46L, I54V, V82A L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, I62V, A71V, I72T, L89I, I93LF
 155976155976JN669848PINAL90M T12M, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I72T, V82I, L89I, I93LF
 182974182974JN670630PINA  T12D, I15V, Q18L, L19I, E35D, M36I, R41K, K45R, K55KR, R57K, Q61N, L63LP, I72AMTV, L89IF
 183349183349JN670642PINAM46L, I54V, L76V, V82A L10I, T12I, I15V, G16E, L19I, K20M, E35DN, M36I, R41RK, R57K, Q61N, L63LH, I85V, L89IF
 205791205791JN671372PINAI54V, I84V, L90M L10I, I13IV, I15V, Q18K, K20M, E35D, M36I, R41K, Q61N, I62V, L63P, I66IV, T74A, L89IF
Diaz (2015)RenG17168RenG17168KT748196PINAV32I, I47A, I50VN83NDL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, V82I, I85V, L89IF
 RenG17206RenG17206KT748234PINAM46I, I47V, I54V, V82A, L90ML33F, F53L, Q58EL10I, I13V, Q18IL, L19V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I66F, A71T, I72IM, L89I, Q92KF
 RenG15620RenG15620KT746648PINAM46I, I54V, L76V, V82A, L90M L10I, I13V, I15IV, G16E, K20I, E35N, M36I, N37NS, R41RK, K55R, R57K, Q61N, L63H, A71T, I72V, L89I, T91SF
 RenG15534RenG15534KT746562PINAG48V, I54S, V82AK43TL10I, I15V, K20R, E35D, M36I, N37NS, R41RK, R57K, Q61N, I62V, A71V, I72T, T74S, L89I, I93LF
 RenG16059RenG16059KT747087PINAM46I, I54V, V82A, N88SL33F, K43KTL10I, I13V, I15V, K20T, E35D, M36I, R41N, R57K, Q61N, I62V, I64V, I72R, T74S, L89I, I93LF
 RenG15931RenG15931KT746959PINAM46I, I47V, I54V, V82AK43T, F53LL10I, T12E, L19I, K20R, E35D, M36I, N37T, R41K, K55R, R57K, Q61N, I62V, L63T, I66F, I72V, T74S, V77VI, L89I, T91S, Q92K, F99FLF
 RenG16477RenG16477KT747505PINAM46I, I54V, L76V, V82A L10I, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, L89IF
 RenG17232RenG17232KT748260PINAM46I, I47V, I50V, L76V, V82AV11I, L33F, F53LL10V, I13V, I15V, Q18L, L19Q, K20R, E34KNRS, E35D, M36I, N37D, R41K, R57K, Q61N, I66F, A71V, L89I, T91AF
 RenG15985RenG15985KT747013PINAI84C I13V, I15V, G17E, K20I, E35D, M36I, R57K, D60E, Q61N, L63P, L89I, N98IF
 RenG17442RenG17442KT748470PINAM46I, I47V, I54V, V82F, L90MK43TL10I, I13V, K14R, I15V, K20T, E35N, M36I, R41K, R57K, D60E, Q61D, I72T, V77I, L89IF
 RenG16952RenG16952KT747980PINAM46MI, I50L, I54IV, V82VA, L90ML33LF, K43T, T74PL10V, I13V, I15V, K20V, E35DN, M36I, R41K, K55R, R57K, Q61N, L63LP, E65ED, I66IF, A71AT, I72T, L89I, T91TSF
 RenG15729RenG15729KT746757PINAM46L, I54V, L76V, V82AL33FL5LF, W6L, L10V, I13V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, G68D, L89IF
 RenG16459RenG16459KT747487PINAM46I, I54V, V82F, L90ML33I, K43TL10V, I13V, K20T, E35D, M36L, N37D, R41K, F53Y, R57K, Q61N, I62V, L63P, T74S, V77I, L89I, I93LF
 RenG16312RenG16312KT747340PINAM46L, I47A, L90M I13V, I15V, K20MT, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71T, I72T, V82I, L89I, I93LF
 RenG17275RenG17275KT748303PINAM46L, I54V, V82A, L90M L10I, I13V, K14R, I15V, L19V, K20T, E35N, M36I, N37D, R41K, Q61N, A71V, I72T, T74S, L89I, I93LF
 RenG16860RenG16860KT747888PINAV32I, M46I, I47IV, I54IV, V82AK43TL10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61DE, L63H, I85V, L89IF
 RenG14503RenG14503KT745531PINAM46I, I50V, I54V, V82A L10I, T12K, I13V, K14R, L19P, K20M, E35D, M36I, R41K, R57K, Q61N, I62IV, I64IV, T74S, L89IF
 RenG14245RenG14245KT745273PINAM46I, G48GA, I54V, V82AL33I, F53FL, N83DL10I, I13V, K20R, A22V, E35D, M36I, N37T, R41K, R57K, Q61N, I62V, L63AP, A71T, I72T, L89IF
 RenG14526RenG14526KT745554PINAD30N, M46I, I47V, I54V, V82A, L90ML33F, F53L, Q58E, N88DL10V, T12K, I15V, G16Q, K20T, E35S, M36I, P39S, R41K, K45R, R57K, D60E, Q61D, L63P, A71I, L89IF
 RenG14597RenG14597KT745625PINAM46L, I54V, V82AL33I, K43T, F53L, N83DL10I, I13V, K20R, A22V, E35D, M36I, R41K, K55R, R57RK, Q61N, A71T, I72T, T74AS, L89I, T91SF
 RenG14436RenG14436KT745464PINAM46L, G48V, I54V, V82AL24IL10V, I15V, L19I, K20R, E35D, M36I, N37D, R41K, F53Y, K55R, R57K, D60E, Q61E, I62V, L63P, A71T, I72T, T74TA, L89I, T91SF
 RenG15110RenG15110KT746138PINAG48GA, I50IL, I54V, V82AT, L90ML33LI, F53FLL10I, T12K, I15V, L19P, K20V, E35D, M36I, N37NT, R41K, R57RK, Q61N, H69HR, K70KQ, A71AITV, T74S, V77VI, I85V, L89I, I93ILF
 RenG13750RenG13750KT744778PINAM46I, G48V, I50V, I54T, V82AL33FL10I, I15V, K20R, E34N, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, I85V, L89I, I93LF
 RenG14383RenG14383KT745411PINAI54V, L90ML33I, F53L, N83DL10I, I13V, A22V, E34EAKT, E35D, M36I, N37D, R41K, D60E, Q61N, I62V, A71T, L89IF
 RenG14943RenG14943KT745971PINAG48V, I54V, V82A, L90ML33FL10IV, I13V, K14R, I15V, K20M, E35D, M36I, N37I, R41K, R57K, Q61N, T74S, L89I, Q92K, I93L, C95FF
 RenG13602RenG13602KT744630PINAI50L, V82A, L90ML33F, F53LL10V, I13V, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, I62V, G68E, H69HY, A71V, I72T, L89IF
 RenG14761RenG14761KT745789PINAD30N, G48V, I54V, V82AL24I, L33F, F53LL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89I, T91TS, Q92KF
 RenG15104RenG15104KT746132PINAG48V, I54V, V82A, L90ML33LFL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37NIK, R41K, R57K, Q61N, T74S, L89I, Q92K, I93L, C95FF
 RenG13656RenG13656KT744684PINAV32I, M46I, I47V, I54V, V82A, L90ML10F, Q58EI15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61N, L63P, A71V, L89I, I93LF
 RenG15101RenG15101KT746129PINAM46I, I54S, V82A, L90ML33I, K43TL10I, K14T, I15V, L19V, K20R, E35D, M36I, N37D, K55R, Q61N, T74S, I85V, L89IF
 RenG14867RenG14867KT745895PINAM46I, I47AL10F, L33LI, F53LT12I, I13V, I15V, Q18E, K20M, E35N, M36I, R41K, K45R, R57K, Q61N, L89IF
 RenG14681RenG14681KT745709PINAM46L, I54V, V82A, L90ML33I, N88DL10I, I13V, G16E, G17D, L19I, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63H, A71I, L89I, I93LF
 RenG13739RenG13739KT744767PINAM46L, I54V, V82A, L90M L10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61D, I72T, L89IF
 RenG14046RenG14046KT745074PINAI47V, G48A, I54A, V82AS L10I, I15V, G16GE, K20R, E35D, M36I, N37ND, R41K, K43KR, K45KR, R57K, Q61N, L63Q, A71V, I85V, L89I, Q92K, I93LF
 RenG14160RenG14160KT745188PINAM46L, I54V, V82AL24I, L33F, Q58EL10I, K14T, L19Q, K20R, E35D, M36I, K55R, R57K, D60E, Q61N, I62V, L63P, E65D, I72IM, L89I, Q92KF
 RenG13960RenG13960KT744988PINAG48A, I54V, V82AF53LL5LP, W6L, L10I, I13N, I15L, G16E, E35D, M36I, P39S, R41K, K55R, R57K, D60E, Q61D, I62V, H69Y, A71AV, I72R, T74A, L89I, I93ILF
 RenG11970RenG11970KT742998PINAM46L, G48MV, I54V, V82A, L90ML33LF, K43T, T74PL10V, K20R, E35D, M36I, R41K, R57K, Q61D, I62V, L63P, A71V, I72AT, L89I, T91A, I93LF
 RenG12947RenG12947KT743975PINAM46I, I54V, L76V, V82AV11VI, L33I, N83DL10V, I13A, K14KR, A22V, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63P, L89IF
 RenG13104RenG13104KT744132PINAM46I, I47V, I54V, V82AL24I, L33IL10V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, L89I, Q92K, N98IF
 RenG13137RenG13137KT744165PINAM46I, I54A, V82A, L90ML33IL10I, T12P, I15V, L19P, K20V, E35N, M36I, R41K, R57K, Q61N, I62V, K70E, A71V, T74S, G86GA, L89I, T91S, I93LF
 RenG11988RenG11988KT743016PINAI54V, V82A L10V, T12I, I13V, I15IV, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, I72T, L89IF
 RenG12485RenG12485KT743513PINAM46L, I54V, V82A I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, T74S, L89IF
 RenG12665RenG12665KT743693PINAG48QR, I84V, L90ML33F, N83DL10V, K20R, E35D, M36L, R41K, R57K, Q61D, I62V, L63P, T74S, L89IF
 RenG12409RenG12409KT743437PINAM46L, I54V, I84VN83DL10I, T12I, I13V, A22V, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, K70R, T74A, L89I, T91SF
 RenG13102RenG13102KT744130PINAL90M L10V, I13V, I15V, K20T, E35D, M36I, R41K, R57RK, Q61N, G68E, A71T, L89IF
 RenG13395RenG13395KT744423PINAM46I, I54V, L76V, L90MQ58QET12K, I15V, G16E, K20T, E35D, M36I, N37E, R57K, D60E, Q61N, L63S, H69HR, L89IF
 RenG13242RenG13242KT744270PINAM46ML, I54V, V82A, L90MF53FLL10V, I15V, G16A, L19LV, K20R, E35D, M36I, N37NDIV, R41K, K55R, R57K, Q61N, L63LP, T74S, I85IV, L89I, Q92QKF
 RenG13505RenG13505KT744533PINAL90M L10V, I13V, K20R, E35D, M36L, R41K, R57K, Q61N, I62V, L63P, T74S, L89I, I93LF
 RenG13420RenG13420KT744448PINAV82AV32A, L33FL10V, I13V, I15V, Q18E, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, E65D, A71V, I72V, L89I, I93LF
 RenG12768RenG12768KT743796PINA  K20I, E35D, M36I, R41K, K43R, R57K, Q61N, T74S, L89I, I93LF
 RenG12818RenG12818KT743846PINAV32I, I47AV, I50L I15V, K20T, E35D, M36I, R41K, R57K, Q61S, K70R, A71V, V82I, I85V, L89IF
 RenG12196RenG12196KT743224PINAI54IV, V82A, L90M I15V, G16E, K20M, E35N, M36I, N37D, G40R, R41K, R57K, Q61N, K70R, L89I, L97*F
 RenG12025RenG12025KT743053PINAM46L, I54V, V82AL24I, F53FLL10IV, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, L63LP, A71AT, L89I, Q92QKF
 RenG12608RenG12608KT743636PINAI54V, V82A, L90ML33FL10V, I13V, I15V, K20T, E35D, M36IL, R41K, R57K, Q61N, I62IV, L63DE, A71T, I72T, L89IF
 RenG12683RenG12683KT743711PINAI54V, V82TL24IL10I, T12TK, I13V, K20I, E35D, M36I, R41K, R57K, Q61N, L63A, T74S, L89IF
 RenG12672RenG12672KT743700PINAV32I, I47A L10V, I13V, G16E, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63S, A71AT, I72E, V82I, L89IF
 RenG12250RenG12250KT743278PINAI54V, V82AV11VI, L33LI, F53LL5LF, W6C, Q7K, T12I, I13V, G16E, K20I, E35D, M36I, R41K, R57K, Q61D, I62V, A71V, I72R, T74A, L89I, T96XF
 RenG11817RenG11817KT742845PINAG48V, I54S, V82ACGSV11I, L33LF, T74PSL10I, T12K, I13V, K14R, I15V, K20T, E35N, M36I, R41P, R57K, Q61N, L89IF
 RenG13067RenG13067KT744095PINAV32I, M46L, I47A, L90M I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, I64IM, I72V, V77I, V82I, L89I, I93LF
 RenG12539RenG12539KT743567PINAM46I, I54V, L76V, I84VN83DR8X, L10I, T12I, I13A, G16E, K20R, A22V, E35D, M36I, R41K, R57K, Q61N, I72R, L89IF
 RenG13129RenG13129KT744157PINAM46L, I54V, V82A, L90MN88DL10V, I13K, I15G, K20I, E35N, M36I, L38F, R41K, R57K, Q61H, L63I, A71T, T74S, L89I, Q92KF
 RenG11775RenG11775KT742803PINAM46L, I54V, L76LV, V82A, L90M L10V, K14R, I15V, G16E, K20MT, E35N, M36I, N37D, R41K, K55KR, R57K, Q61N, I62IV, L63HP, T74S, V77VI, I85V, L89I, I93LF
 RenG11433RenG11433KT742461PINAI54A, V82A, L90M L10I, I13V, K14R, I15IV, K20R, E35D, M36I, N37D, R41K, K55KR, R57K, Q61N, I62V, L63P, A71V, I72T, T74S, L89I, Q92KF
 RenG11135RenG11135KT742163PINAM46MI, I54V, L90M I13IV, K14KR, I15V, K20T, E35D, M36I, P39V, R41K, R57K, Q61N, I62V, L63A, I72V, T74S, L89I, Q92KF
 RenG11279RenG11279KT742307PINAG48V, I54V, L76V, V82A, I84VM46V, Q58EL10I, I15V, G16E, K20R, E35D, M36I, K55R, R57K, Q61N, L63C, L89IF
 RenG10265RenG10265KT741293PINAM46I, I54V, L76V, V82AL24IL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, I64IL, A71V, I72T, L89I, I93LF
 RenG11470RenG11470KT742498PINAI54V, V82A, L90M L10I, I13V, K20M, L33L_L, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, A71T, L89I, Q92KF
 RenG11085RenG11085KT742113PINAM46I, I54V, L76V, V82AL24IL10V, I15V, K20R, E34Q, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I72T, L89IF
 RenG10018RenG10018KT741046PINAD30N, I54V, V82A, L90ML33F, N88DT12I, I13V, K14R, I15V, K20R, E35D, M36L, N37D, R41K, K45I, R57K, Q61N, I62V, L63P, G68E, H69R, I72IV, L89IF
 RenG11561RenG11561KT742589PINA  K14R, G16E, N37K, R41N, R57K, Q61DN, I64L, I72T, L89IF
 RenG11770RenG11770KT742798PINAM46I, V82F, L90ML33F, K43T, N88GL10IV, I13V, I15V, K20T, E35N, M36I, R57K, Q61D, L63P, A71L, I72T, V77I, L89I, I93LF
 RenG11735RenG11735KT742763PINAM46I, I54V, L76V, L90M L10V, I13V, I15V, K20T, E35N, M36I, R41K, R57K, D60E, Q61N, I62IV, L63P, A71I, L89I, T91S, I93LF
 RenG11078RenG11078KT742106PINAG48V, I50L, I54V, V82A L10V, K14R, I15V, L19V, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, G68D, A71AT, I85V, L89IF
 RenG11711RenG11711KT742739PINAM46L, I54V, V82AL24I, L33F, K43T, G48E, F53LL10I, I15V, K20M, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, T74S, L89I, Q92KF
 RenG10048RenG10048KT741076PINAI54V, V82AL33I, K43T, F53L, N83DI13V, G17A, Q18H, K20R, A22V, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, A71T, I72T, T74A, L89I, T91S, Q92HF