<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation N88S
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 46
Isolates 46
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Shafer (2003)A384_40794079bEF549325NFV30N88SL33LFL10I, I15V, K20KT, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, L89MF
Dumans (2004)RG034RG034AY390208NFV131I54V, N88SK43TL10I, K20R, E35D, M36I, R41K, R57K, D60DE, Q61N, I62IV, L63A, I93LF
Gomez-Carrillo (2004)104338104338AY365699PINAN88S L10I, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63AF
 105506105506AY365729PINAN88S I15V, L19I, K20T, E35D, M36I, R41K, K45KR, R57K, Q61N, L89M, I93LF
 114347114347AY365900PINAN88S I13V, I15V, L19I, E35D, M36I, R41K, R57K, Q61N, L63P, I93LF
Non-B Workgroup (2005)BR7BR7AY900887NFV130I54V, N88SK43TL10I, K20R, E35D, M36I, R41K, R57K, D60DE, Q61N, I62IV, L63A, I93LF
Rodrigues (2005)BLF_Pat3BR02SP249AY643146Unknown, NFV>74N88S K20T, E35D, M36I, R41K, R57K, Q61N, V77I, L89MF
 BLF_Pat13BR03SP64AY643176NFV123N88S I15V, G16GE, L19I, K20T, E35D, M36I, N37NT, P39HQ, R41K, R57K, Q61D, I62IV, E65D, L89MF
 BLF_Pat27BR03SP155AY643163NFV35N88S L10V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, E65D, L89MF
 BLF_Pat39BR02SP241AY643145IDV, NFV141N88S L10V, I15V, K20T, E35D, M36I, R57K, Q61D, I72R, L89M, I93LF
 BLF_Pat40BR02SP226AY643142NFV148N88S L10I, I13V, I15IV, K20T, E35D, M36I, R41K, R57K, Q61N, E65D, V77I, L89MF
von Wyl (2007)81496899EF450023PINAN88S L10V, I15V, K20R, E35D, M36I, R41K, I62V, H69Q, L89MF
Dumans (2009)RES299_03RES299_03FJ405039NFV139N88S L10V, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61NF
 RENA432RENA432FJ405047SQV, RTV, IDV, APV, LPV326N88S I15V, K20T, E35D, M36I, R41K, R57K, Q61N, H69Y, I72T, L89MF
 RENA251RENA251FJ405048NFV161N88S L10V, T12K, I13V, K14E, I15V, G16E, K20T, E35D, M36I, R41K, Q61N, E65R, L89MF
 RENA511RENA511FJ405146RTV, IDV, Unknown>61N88S L10V, I13V, I15V, K20R, E35D, M36I, N37T, R41K, K45R, R57K, Q61N, I62V, E65D, I72V, L89MF
Jones (2012)166236166236JN670122PINAN88SL10LFII15V, Q18QH, K20I, E35D, M36MI, R41K, K45R, R57K, Q61N, L63LP, I85IV, I93LF
 167774167774JN670161PINAV32I, I47V, I54M, N88S, L90LML33F, G73S, L89VT12I, I13V, I15V, G16E, K20R, E35ED, M36I, R41K, R57K, Q61N, G68GE, A71IV, I72T, V77VEF
 173206173206JN670316PINAM46I, N88S, L90M I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71T, I72T, I93LF
 190411190411JN670797PINAI54V, N88SL33II13V, I15V, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, I62VF
 191149191149JN670811PINAN88S L10LV, I15V, K20T, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63PF
 192094192094JN670846PINAI54L, N88S L10V, T12R, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, T74S, V77I, I93LF
Diaz (2015)RenG15609RenG15609KT746637PINAI50L, N88SL33FT12N, I13IV, I15V, L19I, K20I, E35N, M36I, N37D, R41K, R57K, Q61N, L63V, I64V, I72V, T74TA, V77VI, L89MF
 RenG15688RenG15688KT746716PINAN88S L10I, I15V, K20T, E35D, M36I, P39Q, R41K, R57K, Q61N, L63A, A71T, I85VF
 RenG16059RenG16059KT747087PINAM46I, I54V, V82A, N88SL33F, K43KTL10I, I13V, I15V, K20T, E35D, M36I, R41N, R57K, Q61N, I62V, I64V, I72R, T74S, L89I, I93LF
 RenG15542RenG15542KT746570PINAI50L, N88SL33FI13V, K20R, E35D, M36I, N37D, R41K, K45R, R57K, D60E, Q61D, K70R, A71V, L89M, Q92KF
 RenG15848RenG15848KT746876PINAI54L, N88SK43KTL10V, T12TK, K14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61N, L63T, I64V, V77I, L89M, I93LF
 RenG15805RenG15805KT746833PINAI50L, N88S L10M, K14R, I15V, G16E, K20T, E35D, M36I, P39T, R41K, R57K, Q61N, L63T, E65D, I72T, T74A, L89MF
 RenG16619RenG16619KT747647PINAM46I, I50V, I54V, N88S L10I, I15V, K20T, E35D, M36I, R41K, R57K, Q61D, I62V, L63V, I64V, T74A, L89M, I93LF
 RenG14829RenG14829KT745857PINAN88SL33I, Q58EL10I, T12E, I15V, E35N, M36I, P39Q, R41K, R57K, D60E, Q61D, L63Q, I85V, L89MF
 RenG15083RenG15083KT746111PINAM46L, N88S L10V, I15V, G16E, K20R, E35D, M36V, R41K, R57K, Q61N, L63T, E65D, I72TF
 RenG13942RenG13942KT744970PINAN88S L10V, G16E, K20R, E35D, M36V, P39S, K45R, R57K, Q61D, L63V, E65D, I72V, L89MF
 RenG14360RenG14360KT745388PINAN88S L10V, I13V, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63LPF
 RenG13916RenG13916KT744944PINAI54IL, N88SL89VL10V, I13V, K14KR, I15V, K20T, T31A, E35D, M36I, Q61D, A71ATF
 RenG14687RenG14687KT745715PINAI50L, N88SQ58EL10V, I15V, G16GE, K20T, E35D, M36I, R41K, R57K, Q61N, L63LP, T74TA, V77I, L89MF
 RenG15019RenG15019KT746047PINAI50L, V82L, N88SL33FI13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, I72T, T74A, L89MF
 RenG14080RenG14080KT745108PINAN88S L10LV, I13V, K20T, E35D, M36I, R41K, R57K, Q61N, A71T, L89T, Q92QKF
 RenG12914RenG12914KT743942PINAI50L, V82VA, N88SL33FL10I, T12AE, I13V, K14KT, I15IV, K20V, E35N, M36I, N37E, K45R, R57K, Q61N, L63P, I64V, K70T, A71V, V77I, L89M, Q92QKF
 RenG13329RenG13329KT744357PINAN88SF53LG17E, L19I, K20T, E35D, M36I, N37T, R41K, R57K, Q61N, I62V, E65D, A71V, I72V, T74S, V77I, L89M, Q92KF
 RenG11946RenG11946KT742974PINAM46L, N88SQ58EL10V, K20T, E35D, M36I, R57K, Q61N, I62V, L63S, E65D, I72T, V77I, L89M, I93LF
 RenG13021RenG13021KT744049PINAN88SF53L, Q58EL10I, G16E, K20T, E35D, M36V, N37H, P39S, R41K, R57K, D60E, Q61D, L63C, A71V, V77IL, L89M, I93LF
 RenG10683RenG10683KT741711PINAM46I, I54V, N88SL33I, Q58EL10I, I13V, K14KR, K20R, E35D, M36I, R41K, R57RK, Q61N, L63T, I64L, I93LF
 RenG11633RenG11633KT742661PINAM46L, N88SQ58EL10V, I13V, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, V77I, L89MF
 RenG11018RenG11018KT742046PINAI54L, N88S L10V, I13V, K20R, E34A, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, A71T, I72TF
 RenG10664RenG10664KT741692PINAN88SF53FLT12K, I15V, G16E, L19I, K20T, E35D, M36I, P39S, R57K, D60E, Q61N, I62IV, K70KE, V77VI, L89M, Q92QRF
 RenG10504RenG10504KT741532PINAN88S L10LV, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, E65D, V77I, L89M, Q92KF