<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation N88D
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 60
Isolates 60
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Dumans (2004)242242AY390086NFV177D30N, M46IN88DL10V, I13V, R41K, R57K, D60E, Q61D, I64V, V77I, I85VF
Gomez-Carrillo (2004)103183103183AY365671PINAD30N, M46L, I54V, V82A, L90ML33F, N88DI13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63H, A71V, T74S, I93LF
 109590109590AY365824PINAD30NN83D, N88DL10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, I72R, L89MF
de Sa Filho (2005)BREPM275BREPM275AY771592PINAD30NL33F, N88DL10V, T12K, I13V, I15V, K20T, E35D, M36L, N37E, K55R, R57K, D60E, Q61N, L63S, L89MF
Rodrigues (2005)BLF_Pat16BR03SP111AY643159SQV, IDV, NFV293D30NN88DL10I, I13V, I15V, K20R, E35D, M36V, N37NS, R41K, R57K, Q61N, I62IV, L63LP, E65D, A71I, I72TF
 BLF_Pat41BR02SP138AY643137Unknown, NFV>11D30N, M46MLN88DL10V, I13V, I15V, K20R, E35D, M36I, N37NI, R41K, K45KR, R57K, Q61D, A71T, I72TF
Waleria-Aleixo (2008)08PR05030708PR050307FJ591335PINAD30N, I54LN88DI13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63H, A71IV, I72IV, Q92RF
 08RJ06060408RJ060604FJ591764PINAD30N, M46IN88DL10V, G16Q, E35D, M36V, P39T, R41K, K43R, R57K, D60E, Q61N, T74S, L89MF
 08RJ04015508RJ040155FJ591626PINAD30NN88DL10V, I13V, I15V, K20R, E35D, M36I, N37H, R41K, R57K, Q61N, I64V, H69Y, I72T, L89MF
 08PR06056608PR060566FJ591481PINAM46I, I54V, V82AK43T, N88DL10I, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I64V, E65D, A71V, I72R, L89M, I93LF
 08RJ05046408RJ050464FJ591658PINAM46L, I54V, I84V, L90MN88DL10I, I15V, K20T, E35D, M36I, P39Q, R41K, K45R, R57K, Q61N, L63P, I66F, K70R, A71V, I72V, V77I, L89M, Q92KF
Dumans (2009)RENA101RENA101FJ405038NFV78 N88DV11VF, I15V, K20T, E35D, M36I, R41K, R57K, Q61D, I72V, V77I, L89MF
 RENA636RENA636FJ405049NFV243D30NN88DI13V, I15V, K20T, E35D, M36I, R41K, Q61D, L63P, T74SF
 RENA140RENA140FJ405170NFV91D30NN88DL10I, I13V, I15V, E35D, M36I, R41K, R57K, Q61D, L63C, K70R, I72T, L89MF
Sanabani (2010)81007BR_FPS810HM026459PINAD30N, I50L, V82AL33F, N88DL10V, I13V, I15V, K20R, E35D, M36L, R41K, K45Q, R57K, Q61N, L63P, I64L, A71V, I93LF
Aulicino (2011)ARL411LCOARL411LCOFJ525808PINAD30NN88DL10Y, I13V, I15V, K20T, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63H, I72V, V75IF
 ARN156RJEARN156RJEFJ525852PINAD30N, M46I, I54V, V82AL24I, L33F, N83D, N88DL10I, K20R, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63D, A71V, I72PT, T74SF
 2166-N870ZLT2166-N870ZLTHQ158183PINAD30NL10F, N88DI13V, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, L63P, I72TF
Jones (2012)147856147856JN669701PINAD30NN88DK14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, H69Q, K70R, V75IF
 157578157578JN669892PINAD30N, I54VN88DK14R, G17E, K20R, E35D, M36V, N37E, R41K, K43R, R57K, Q61N, L63T, E65D, H69Y, I72T, T74S, L89MF
 166492166492JN670129PINAD30N, M46LN88DI15V, L19LQ, K20T, E35D, M36I, R41K, R57K, Q61N, I64IV, E65D, A71V, I72TF
 179226179226JN670504PINAD30N, I54V, L90MV11VI, Q58E, N88DI15V, K20IMT, E35NS, M36I, N37D, R41K, R57K, Q61N, L63P, A71T, I72TF
 179417179417JN670509PINAM46L, V82AN88DG16E, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63H, I64IL, A71VF
 193453193453JN670899PINAM46I, I47V, I54V, V82AL10F, K43T, N88DI15V, L19IT, K20I, E35N, M36I, R41RK, R57K, D60E, Q61N, I62IV, L63P, A71V, I85IVF
Diaz (2015)RenG16086RenG16086KT747114PINAD30NQ58E, N88DK20T, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, L89MF
 RenG16870RenG16870KT747898PINAD30DN, M46ML, I54IV, V82VAN88DL10*Y, T12TA, I15V, G16AE, K20MV, E35DN, M36I, R41K, Q61N, L63LP, I72EF
 RenG17379RenG17379KT748407PINAD30NN88DL10I, T12I, I13V, I15V, K20T, E35N, M36I, R41K, K45R, R57K, Q61N, L63DG, I72T, L89MF
 RenG16858RenG16858KT747886PINAD30NN88DT12I, I13V, I15V, Q18E, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, I64L, E65ED, I72V, L89MF
 RenG16451RenG16451KT747479PINAD30NL10F, L33I, N88DQ7E, K20T, E35DN, M36I, R41K, R57K, D60E, Q61E, L63P, I72VF
 RenG17425RenG17425KT748453PINAD30N, I54VN88DL10Y, T12TA, I15V, G16E, K20R, E35D, M36V, P39Q, R41RK, R57K, D60E, Q61D, L63T, A71V, I72T, L89T, I93LF
 RenG17438RenG17438KT748466PINAD30N, M46I, I50L, L90MK43T, N88DI13V, K14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61D, I62V, L63P, A71V, V77I, I85IVF
 RenG16844RenG16844KT747872PINAD30N, M46I, I50L, L90MK43T, N88DI13V, K14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61D, I62V, L63P, A71V, V77I, I85IVF
 RenG14526RenG14526KT745554PINAD30N, M46I, I47V, I54V, V82A, L90ML33F, F53L, Q58E, N88DL10V, T12K, I15V, G16Q, K20T, E35S, M36I, P39S, R41K, K45R, R57K, D60E, Q61D, L63P, A71I, L89IF
 RenG14668RenG14668KT745696PINAD30N, I50L, V82A, L90ML33F, N88DI13V, I15V, K20R, E35D, M36I, R41K, K55N, R57K, Q61N, L63P, A71V, I72M, V77I, Q92QRF
 RenG13940RenG13940KT744968PINAD30NL10F, N88DI13V, I15V, K20T, E35D, M36I, R41K, K45R, K55N, R57K, Q61N, L63H, E65DF
 RenG14457RenG14457KT745485PINAD30N, I54IL, L90LMF53FL, T74TP, N88DT12N, I15V, K20T, E35DN, M36I, R41K, K45KR, R57K, D60E, Q61N, L63P, I66IF, H69HY, A71AITV, V77VI, L89LMST, I93LF
 RenG14681RenG14681KT745709PINAM46L, I54V, V82A, L90ML33I, N88DL10I, I13V, G16E, G17D, L19I, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63H, A71I, L89I, I93LF
 RenG14541RenG14541KT745569PINAD30N, M46MI, I50LL33I, N88DT12E, L19V, K20R, E21EK, E35D, M36I, N37IT, R41K, R57K, Q61D, L63P, I66IV, A71T, I93LF
 RenG15203RenG15203KT746231PINAD30N, L90MN88DI13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, I64L, T74S, V77VI, L89M, I93LF
 RenG15507RenG15507KT746535PINAD30N, L90LML23I, L33I, K43KT, T74TP, N88DL10M, T12I, I13V, E35D, M36I, N37I, R41K, F53I, R57K, Q61N, I62V, L63P, A71AT, I93LF
 RenG13959RenG13959KT744987PINAD30N, L90ML33LI, N88DL10Y, I15V, K20T, E35DN, M36I, N37D, R41K, R57K, Q61N, I62V, A71T, T74S, V77I, I85V, L89T, Q92QKRF
 RenG12430RenG12430KT743458PINAD30N, M46L, I50L, V82AN88DL10V, T12A, I13V, I15S, G16R, K20R, E21Q, E35D, M36I, N37T, R41K, K45R, R57K, Q61N, I62V, L63AD, A71V, I72IV, T74TS, I85IV, Q92QRF
 RenG12347RenG12347KT743375PINAD30N, M46I, L90MF53L, N88DL10V, I13V, I15V, K20R, E35D, M36I, N37T, P39Q, K55R, R57K, D60E, Q61D, I62V, L63P, A71T, I72TF
 RenG13393RenG13393KT744421PINAD30NL33F, F53L, N88DI15V, L19Q, K20T, E35D, M36I, N37NT, R41K, K45I, R57K, D60E, Q61E, I62V, L63P, I66F, A71V, T74S, V77I, V82I, L89T, Q92RF
 RenG13532RenG13532KT744560PINAD30N, M46L, I54IV, V82A, L90ML33F, F53L, N88DL10V, T12Q, I13V, I15V, G16GE, K20R, E35D, M36I, R41K, K55KN, Q61N, L63S, I93ILF
 RenG12314RenG12314KT743342PINAD30N, I54LL33F, Q58QE, N88DR8P, L10V, I13V, I15V, K20T, T31A, E35D, M36I, K43R, R57K, Q61N, L63C, T74S, L89IMF
 RenG12824RenG12824KT743852PINAD30N, M46L, I54V, V82AL33I, F53L, N83D, N88DL10I, I13V, G16E, K20R, A22V, E35N, M36I, N37T, K45R, R57K, Q61N, L63T, E65D, A71V, I72T, T74S, V75I, L89M, Q92KF
 RenG12301RenG12301KT743329PINAD30N, I50LN88DT12N, I15V, L19I, K20T, E35D, M36I, N37T, R41K, K45R, Q61D, L63C, E65D, A71LV, V77IF
 RenG12636RenG12636KT743664PINAD30N, V32VI, M46I, I47V, I54LVF53FL, L76LM, N88DL10V, T12IM, I13A, K20T, A22AV, E35N, M36I, N37ND, R41K, K45R, R57K, Q61N, L63C, A71V, T74S, L89T, Q92RF
 RenG12278RenG12278KT743306PINAD30NF53L, N88DL10V, I13V, I15V, K20T, E35D, M36I, Q61N, A71V, T74S, V77I, L89T, Q92RF
 RenG13474RenG13474KT744502PINAD30NN88DL10I, I13V, K14KR, E35D, M36I, R57K, Q61N, L63P, I72IT, L89LMF
 RenG13314RenG13314KT744342PINAV82A, L90MN88DL10I, I13IV, G16A, K20R, E35D, M36I, N37ND, R41K, K43KR, R57K, Q61N, L63P, I64IV, K70KN, A71V, I72V, I93IMF
 RenG13129RenG13129KT744157PINAM46L, I54V, V82A, L90MN88DL10V, I13K, I15G, K20I, E35N, M36I, L38F, R41K, R57K, Q61H, L63I, A71T, T74S, L89I, Q92KF
 RenG11186RenG11186KT742214PINAD30N, M46I, L90MF53L, N88DL10V, I13V, I15V, K20R, E35D, M36I, N37T, P39Q, K55R, R57K, D60E, Q61D, I62V, L63P, A71T, I72TF
 RenG10881RenG10881KT741909PINAD30NL10F, N88DI13V, K20R, E35D, M36I, K45KR, R57K, Q61D, I64V, E65D, I72TF
 RenG11499RenG11499KT742527PINAM46I, I54V, V82A, L90MN88DW6WG, L10V, I15V, K20R, E35D, M36I, R41K, K45R, K55KR, R57K, Q61N, L63P, A71I, L89M, I93LF
 RenG10185RenG10185KT741213PINAD30NN88DI13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, I64L, K70R, V75I, L89MF
 RenG10136RenG10136KT741164PINAD30N, I50V, I54V, V82A, L90LML33F, N88DL10V, I13V, K20R, E35D, M36I, N37E, R41Y, K45Q, R57K, Q61N, L63ST, E65D, A71L, L89LM, I93LF
 RenG11102RenG11102KT742130PINA N88DI15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63N, A71TF
 RenG10251RenG10251KT741279PINAD30N, I50L, V82AL33LF, M46MV, N88DL10V, T12I, I13V, I15V, G16E, E35D, M36I, R41K, K45R, R57K, Q61N, L63C, I64L, A71V, I72L, L89IT, I93LF