<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation N88D
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 74
Isolates 74
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Dumans (2004)242242AY390086NFV177D30N, M46IN88DL10V, I13V, R41K, R57K, D60E, Q61D, I64V, V77I, I85VF
Gomez-Carrillo (2004)101508101508AY365639PINAD30NN88DK14R, I15V, K20T, E35D, M36I, N37H, R41K, R57K, Q61N, A71V, I93LF
 101510101510AY365641PINAD30NN88DI15V, K20R, E35D, M36V, R57K, Q61D, I62V, L63P, I93LF
 103183103183AY365671PINAD30N, M46L, I54V, V82A, L90ML33F, N88DI13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63H, A71V, T74S, I93LF
 103620103620AY365684PINAD30N, L90MN88DI13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63D, A71T, I72TF
 104950104950AY365714PINAD30NN88DI13V, K20KR, E35D, M36I, R41K, Q61N, I62V, L63P, I64IM, I93ILF
 105848105848AY365738PINAD30N, M46MLN88DI15V, G17E, K20T, E35D, M36I, N37NS, R41RK, R57K, Q61N, L63LPF
 109590109590AY365824PINAD30NN83D, N88DL10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, I72R, L89MF
 114305114305AY365896PINAD30NQ58E, N88DL10I, I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, I72V, V77I, I93LF
 124413124413AY366032PINAD30NN88DI15V, K20T, E35D, M36I, N37D, R41K, R57K, D60E, Q61D, L63P, I93LF
de Sa Filho (2005)BREPM275BREPM275AY771592PINAD30NL33F, N88DL10V, T12K, I13V, I15V, K20T, E35D, M36L, N37E, K55R, R57K, D60E, Q61N, L63S, L89MF
Rodrigues (2005)BLF_Pat16BR03SP111AY643159SQV, IDV, NFV293D30NN88DL10I, I13V, I15V, K20R, E35D, M36V, N37NS, R41K, R57K, Q61N, I62IV, L63LP, E65D, A71I, I72TF
 BLF_Pat41BR02SP138AY643137Unknown, NFV>11D30N, M46MLN88DL10V, I13V, I15V, K20R, E35D, M36I, N37NI, R41K, K45KR, R57K, Q61D, A71T, I72TF
Baxter (2006)48-11361136-30729DQ877275PINAM46I, I47V, I54V, V82FL33F, K43T, N88D, L89LVL10I, I15V, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, A71V, I85V, I93LF
 48-11571157-30918DQ877419PINAI54V, V82AN88DL10I, I15V, K20R, E35D, M36I, R41K, K43KR, K45R, R57K, Q61D, L63P, A71T, I93LF
Dumans (2009)108PR108PRFJ405037NFV, Unknown>26D30NN88DI15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, A71V, V77I, I93LF
 RENA101RENA101FJ405038NFV78 N88DV11VF, I15V, K20T, E35D, M36I, R41K, R57K, Q61D, I72V, V77I, L89MF
 RENA636RENA636FJ405049NFV243D30NN88DI13V, I15V, K20T, E35D, M36I, R41K, Q61D, L63P, T74SF
 RENA140RENA140FJ405170NFV91D30NN88DL10I, I13V, I15V, E35D, M36I, R41K, R57K, Q61D, L63C, K70R, I72T, L89MF
Sanabani (2010)81007BR_FPS810HM026459PINAD30N, I50L, V82AL33F, N88DL10V, I13V, I15V, K20R, E35D, M36L, R41K, K45Q, R57K, Q61N, L63P, I64L, A71V, I93LF
Aulicino (2011)ARM640RCAARM640RCAFJ525835PINAD30NN88DL10V, T12I, I15V, G16E, E35D, M36V, N37E, R41K, K45R, R57K, Q61N, L63T, I72T, V77I, I93LF
 ARM804TJXARM804TJXFJ525841PINAD30NN88DT12M, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61D, A71T, I72T, T74S, I85VF
 ARN156RJEARN156RJEFJ525852PINAD30N, M46I, I54V, V82AL24I, L33F, N83D, N88DL10I, K20R, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63D, A71V, I72PT, T74SF
 ARN185RNWARN185RNWFJ525853PINAD30NN88DL10I, T12D, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, I93LF
 ARN429AEDARN429AEDFJ525860PINAD30NN88DL10V, I15V, E35D, M36I, R41K, R57K, Q61D, L63P, V75I, L89M, I93LF
 ARN926MRDARN926MRDFJ525867PINAD30NN88DL10V, T12I, I15V, K20A, E35N, M36I, N37D, R41K, K45R, R57K, Q61N, L63V, A71V, I72TF
 3516-L418FPF3516-L418FPFHQ158151PINAD30NN88DK14R, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, V82I, L90F, I93LF
 3343-N414ML3343-N414MLHQ158158PINAD30NN88DL10I, I15V, K20T, E35N, M36I, R41K, R57K, D60E, Q61D, L63P, V77I, I93LF
 3225-O153AGL3225-O153AGLHQ158161PINAD30N, L90MN88DT12A, K14R, K20T, E35D, M36I, N37D, R41N, R57K, Q61N, L63P, T74S, V77I, I93LF
 326-M430DCM326-M430DCMHQ158166PINAD30NN88DT12E, I15V, L19R, K20T, E35D, M36I, R41K, K43S, R57K, Q61N, L63P, T74SF
 2166-N870ZLT2166-N870ZLTHQ158183PINAD30NL10F, N88DI13V, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, L63P, I72TF
 352-O64MD352-O64MDHQ158193PINAD30NN88DT12K, I13V, I15V, E35D, M36I, N37D, R41K, R57K, Q61N, A71T, I72T, V75IF
 2125-K3102125-K310HQ158233PINAD30NN88DI15V, K20T, E35D, M36I, R41K, R57K, Q61D, L63P, A71T, I93LF
 3318-K6303318-K630HQ158235PINAD30NN88DI15V, K20T, E35N, M36I, R41K, R57K, Q61N, L63P, I72M, T74SF
Jones (2012)130424130424JN669487PINAD30NN88DT12I, I13V, I15V, K20T, E35D, M36I, R41K, K45R, K55R, R57K, Q61N, G68E, A71VF
 143766143766JN669646PINAD30NN88DI15V, K20T, E35N, M36I, P39PS, R41K, R57K, Q61N, A71T, I72IT, T74S, I93LF
 143960143960JN669647PINAD30NN88DI15V, K20T, E35DN, M36I, R41K, R57K, Q61D, H69Y, A71V, I72T, I93LF
 146738146738JN669681PINAD30NN88DT12M, I13IV, I15V, K20KT, E35D, M36I, R41K, R57K, Q61N, L63P, I64M, I93LF
 147856147856JN669701PINAD30NN88DK14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, H69Q, K70R, V75IF
 151205151205JN669757PINAD30N, L90ML33LF, N88DI13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, A71AT, I93LF
 154303154303JN669816PINAD30N, L90MN88DI13V, I15V, K20T, E35N, M36I, R41K, K43R, K55N, R57K, Q61N, L63P, A71V, Q92KF
 154866154866JN669826PINAD30NN88DK20R, E35D, M36I, N37D, R57K, Q61N, L63P, I72T, V75I, I93LF
 157272157272JN669879PINAD30NN88DI15V, K20T, E35DN, M36I, R41K, R57K, Q61D, T74AF
 157578157578JN669892PINAD30N, I54VN88DK14R, G17E, K20R, E35D, M36V, N37E, R41K, K43R, R57K, Q61N, L63T, E65D, H69Y, I72T, T74S, L89MF
 162130162130JN670029PINAD30NN88DL10V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, I93LF
 165724165724JN670114PINAD30NN88DI15IV, K20T, E35N, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, I64L, A71AV, V77I, I93LF
 166050166050JN670121PINAD30NL10LF, L33LF, N88DT12K, I15V, L19I, K20T, E35D, M36I, R41K, R57K, Q61D, L63P, E65D, I93LF
 166492166492JN670129PINAD30N, M46LN88DI15V, L19LQ, K20T, E35D, M36I, R41K, R57K, Q61N, I64IV, E65D, A71V, I72TF
 170718170718JN670231PINAD30NN88DL10I, I13V, I15V, E35D, M36I, N37E, R41RK, R57K, Q61N, L63P, I93LF
 170845170845JN670236PINAD30NN88DI15V, K20T, E35N, M36I, P39Q, R41K, K45R, R57K, Q61DN, L63AF
 175336175336JN670353PINAD30NN88DI13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63V, I64L, I72E, T74S, L89M, I93LF
 176249176249JN670391PINAD30NN88DL10LI, I13V, I15V, K20R, E35D, M36I, N37D, R41K, K43I, R57K, D60N, Q61N, L63A, V75VIF
 176627176627JN670405PINAD30N, I54IV, I84IV, L90MN88DI15V, G16E, K20RT, E35DN, M36I, P39S, R41K, R57K, Q61N, L63P, A71AT, V75I, I93LF
 176944176944JN670418PINAD30NN88DW6WC, Q7Q*, P9PS, T12N, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, L63AV, E65D, I93LF
 179078179078JN670500PINAD30N, I54V, L90ML33I, N88DL10V, I15V, E35D, M36I, N37D, R41K, K43R, K45R, R57K, Q61N, I62V, L63P, I93LF
 179226179226JN670504PINAD30N, I54V, L90MV11VI, Q58E, N88DI15V, K20IMT, E35NS, M36I, N37D, R41K, R57K, Q61N, L63P, A71T, I72TF
 179417179417JN670509PINAM46L, V82AN88DG16E, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63H, I64IL, A71VF
 179672179672JN670523PINAD30N, L90LMN88DL10I, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, L63P, E65ED, K70R, V77I, I93LF
 181263181263JN670571PINAD30NN88DL10V, I15V, E35D, M36I, R41K, K45KR, R57K, Q61N, L63P, V75VI, I93LF
 182295182295JN670606PINAD30NN88DL10I, T12A, K14R, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, C67D, K70KR, I72IVF
 183035183035JN670635PINAI54V, V82A, L90ML33F, N88DL10I, I15V, K20R, E35D, M36I, N37ND, R41K, K45R, R57K, Q61N, L63P, A71V, I72T, I85V, I93LF
 190546190546JN670800PINAD30N, L90MN88D, L89LVT12K, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63V, T74S, I93LF
 192040192040JN670842PINAD30N, L90ML33F, N88DL10V, T12I, I13V, I15V, E35D, M36IL, N37D, K43Q, R57K, Q61N, L63T, E65D, A71V, I72V, I93LF
 196419196419JN671023PINAD30NN88DL10I, I13V, I15V, K20KR, E35D, M36V, R41K, R57K, Q61DN, L63AV, I93LF
 196720196720JN671038PINAD30NL33F, N88DI15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63A, T74SF
 197154197154JN671063PINAD30NN88DT12I, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, I72T, Q92QKF
 198184198184JN671110PINAD30NN88DI13V, K14R, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63S, A71T, I72M, Q92RF
 198379198379JN671115PINAD30N, L90LMN88DL10V, I15V, G17E, K20RT, E35D, M36I, N37K, R41K, K45R, R57K, Q61D, L63LP, I72R, V75VI, I93ILF
 199010199010JN671147PINAD30N, L90MN88DI13V, I15V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, L63P, I93LF
 199633199633JN671178PINAD30N, M46IF53FL, N88DL10X, I13IV, I15AV, K20T, E35D, M36I, R41K, R57K, Q61N, L63A, A71V, T74S, I85V, I93LF
 200392200392JN671200PINAD30NL33LF, N88DI15V, K20KR, E35D, M36I, R41K, R57K, Q61N, L63LP, I72TF
 201630201630JN671231PINAD30NN88DL10V, T12K, I15V, K20T, E35D, M36I, R41K, R57K, Q61DF
 203859203859JN671318PINAD30NN88DL10I, I15V, K20T, E35D, M36I, N37D, R41K, R57KQ, Q61N, L63HNPT, I93LF
 204424204424JN671341PINAD30N, L90ML33LI, N88DL10LV, E35D, M36IV, R41K, R57K, Q61N, L63P, I66IVF