<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I84V
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 54
Isolates 54
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Apetrei (2003)AC_Pat1RO.01.IS.01AY333463IDV, Unknown, SQV, NFVNAM46I, I54V, V82A, I84VL24I, K43T, G48W, F53LL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat26RO.01.IS.26AY333487IDV, RTV M46I, I54V, V82T, I84V L10V, I15V, E35D, M36I, R41K, K55R, R57K, L63T, E65D, I72V, T74S, L89MF
de Sa Filho (2003)BREPM022BREPM022AY182789IDV D30N, I84V L10I, G16E, P39S, K43R, R57K, Q61N, I64V, V77I, G86R, L89M, I93LF
Gomez-Carrillo (2004)9629696296AY365523PINAI54V, V82AG, I84V, L90ML33F, Q58EQ7QH, L10I, T12TP, I13IV, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, A71V, I72RF
 115855115855AY365925PINAM46ML, I54AV, I84V, L90MV11I, L89VL10I, I13V, G17E, K20V, E35D, M36I, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
de Sa Filho (2005)BREPM107BREPM107AY771588PINAI84V, L90M I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71VF
Baxter (2006)48-11681168-30911DQ877356PINAI54V, V82A, I84VF53LL10V, T12E, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, A71V, T74S, I85V, L89IF
 48-62856285-30924DQ878833PINAI54V, V82T, I84V T4TS, L10V, I13V, I15V, Q18M, L19Q, K20R, E35D, M36I, N37D, R41K, Q61N, A71V, L89IF
Waleria-Aleixo (2008)08PR05037408PR050374FJ591399PINAM46I, L76V, I84V L10I, K20R, E35D, M36I, R57K, Q61D, L63P, H69C, A71V, I72R, L89M, I93LF
 08RJ04011108RJ040111FJ591595PINAI54LV, I84V, L90ML33F, G73SL10I, K14R, G16E, K20R, E35D, M36I, P39S, R41K, K45R, R57K, Q61N, I62V, L63P, C67F, A71V, I72T, I85V, Q92KF
 08PR04021108PR040211FJ591241PINAM46I, I84V, L90M L10V, T12N, I15V, K20R, E35D, M36I, R41K, F53I, R57K, Q61N, L63P, Q92KF
 08RJ05046408RJ050464FJ591658PINAM46L, I54V, I84V, L90MN88DL10I, I15V, K20T, E35D, M36I, P39Q, R41K, K45R, R57K, Q61N, L63P, I66F, K70R, A71V, I72V, V77I, L89M, Q92KF
 RES193RES193FJ591930PINAI84VF53ILL10I, T12A, I13V, K20R, E35D, M36I, R41K, R57K, D60E, Q61E, L63P, V77I, L89MF
 08PR05023608PR050236FJ591265PINAI54V, L76V, I84V, L90M L10I, I15V, G16GA, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, L63LP, A71V, P79S, V82I, L89I, Q92K, I93LF
Dumans (2009)RES165_03RES165_03FJ405046SQV126I84V L10V, I15V, E35D, M36I, R41K, R57K, Q61D, H69Y, I72K, T74SF
 RENA332RENA332FJ405177IDV, SQV, RTV, NFV291I84V, L90M L10V, K20R, E35D, M36I, R41K, D60E, Q61D, I62V, L63P, H69Y, I72T, L89MF
Aulicino (2011)ARM53NBEARM53NBEFJ525823PINAV32I, I84V, L90MG73SI15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, A71VF
Jones (2012)130542130542JN669493PINAI54V, V82A, I84VF53LT4TS, L10V, T12E, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, A71V, T74S, I85V, L89IF
 149342149342JN669733PINAI84V, L90MN83DL10I, L19LI, K20R, E35D, M36I, N37ND, R41K, K45R, R57K, Q61N, I62IV, L63P, I64LF
 151726151726JN669766PINAI54A, I84V, L90MV11I, G73GDNS, L89VL10I, T12TP, I13V, G17E, K20V, E35D, M36I, N37NDEK, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
 162512162512JN670040PINAM46I, I54V, V82S, I84V L10LV, I15V, G16E, K20R, E34A, E35D, M36I, R41K, K43I, K55R, R57K, D60DN, Q61DN, L63C, L89LMF
 173669173669JN670342PINAM46I, I47V, I54V, I84V, L90MV11I, G73SL10I, I15V, G17E, K20I, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, I72R, I85VF
 205791205791JN671372PINAI54V, I84V, L90M L10I, I13IV, I15V, Q18K, K20M, E35D, M36I, R41K, Q61N, I62V, L63P, I66IV, T74A, L89IF
 206165206165JN671393PINAM46L, I54V, I84VL24I, K43T, F53LL10I, I15V, G17D, K20T, E35N, M36I, K55R, Q61N, L63T, E65D, A71V, I72T, T74E, V82I, L89M, I93LF
 207640207640JN671442PINAM46L, G48AEKT, I54V, V82M, I84VL24I, L33I, K43T, F53FLL10I, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63IT, E65D, I72T, T74S, P79PS, L89MF
Kouri (2012)CU263-10CU263-10JQ585374PINAV32I, I54M, I84VV11I, L33F, F53FLQ2L, L5LF, L10V, I13V, K14E, I15V, G17D, K20R, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, L63P, I64V, A71V, T74E, V82IF
Diaz (2015)RenG15726RenG15726KT746754PINAM46L, I54V, V82A, I84V, L90ML33F, K43KPQT, F53FL, T74PSL10V, I13V, I15V, K20R, E35D, M36I, N37D, P39PT, R41RK, K55KR, R57K, Q61N, I62V, L63P, I64L, H69HR, A71IT, L89MT, Q92KF
 RenG17165RenG17165KT748193PINAV32I, M46L, I47IV, I54LV, V82A, I84VL24I, L33FL10I, I13V, G17D, L19I, K20R, E35D, M36I, K43I, R57K, Q61N, L63V, E65D, I72T, T74S, V77IL, L89MF
 RenG16531RenG16531KT747559PINAM46L, I54V, I84V, L90MG73SL10I, K20I, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I85V, L89T, Q92KF
 RenG16813RenG16813KT747841PINAI54V, I84VG73SL10I, K20I, E35N, M36I, R41K, K45R, R57K, Q61N, A71V, I72V, I85V, L89T, Q92QRF
 RenG16827RenG16827KT747855PINAI54V, V82F, I84VF53LL10V, I15V, G16E, K20T, E35D, M36I, P39Q, R41K, K45V, R57K, D60E, Q61D, I72R, T74A, V77I, L89MF
 RenG16754RenG16754KT747782PINAV32I, M46I, I47V, I54M, V82VA, I84V, L90MV11I, L33F, K43TL10IV, I13V, E34K, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, I85IV, L89M, Q92QRF
 RenG16019RenG16019KT747047PINAI54V, I84V, L90ML10FI13V, K20T, L33V, E35D, M36I, N37S, R41RK, F53FI, R57K, Q61N, I66F, A71T, I72T, L89I, Q92KF
 RenG13828RenG13828KT744856PINAM46I, I47V, I54V, V82T, I84VL33F, K43T, F53L, T74PL10I, I13IV, K20R, E35D, M36I, N37ND, R41K, D60DE, Q61N, I62IV, L63P, A71V, Q92QRF
 RenG13971RenG13971KT744999PINAM46I, I47IV, I54IV, L76V, I84V L10I, I15IV, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, A71V, I72R, L89M, I93LF
 RenG14104RenG14104KT745132PINAG48M, V82S, I84VL24I, L33F, K43T, F53LL10V, I15IV, G16A, L19LV, K20R, E35D, M36I, N37K, R41K, R57K, D60E, Q61N, I62V, L63P, T74S, L89MF
 RenG15158RenG15158KT746186PINAM46I, I54V, L76V, V82T, I84VK43TL10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, D60DE, Q61N, L63P, I64L, A71V, I72VF
 RenG14385RenG14385KT745413PINAM46L, G48Q, I54V, L76V, I84VL24IL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57RK, Q61N, L63T, I64L, I72T, V82VI, L89M, Q92QKF
 RenG13955RenG13955KT744983PINAI54IV, I84VL10F, T74PI13V, I15V, K20MT, E35EDG, M36MI, N37NS, R41K, K45R, F53FI, V56VA, R57K, Q61N, I62IV, L63AV, I64V, V77VI, L89MF
 RenG15132RenG15132KT746160PINAI84VL10FG16E, K20R, E35D, M36I, N37ND, R41RK, R57K, D60E, Q61D, I62V, I72T, V77I, L89MF
 RenG12432RenG12432KT743460PINAM46L, I54V, I84VL24I, G48EL10I, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, I64L, I72T, V82VI, L89M, Q92KF
 RenG12139RenG12139KT743167PINAV32VI, I47V, I54L, I84V, L90ML33F, K43KT, F53L, T74PL10I, I13V, K14KR, I15V, Q18QL, K20R, E35D, M36I, R41RK, R57RK, Q61QHKN, I62V, A71V, L89LFF
 RenG11912RenG11912KT742940PINAI54L, I84V, L90ML33F, G73GCL10V, I13V, Q18H, L19I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, I72V, V77IF
 RenG12665RenG12665KT743693PINAG48QR, I84V, L90ML33F, N83DL10V, K20R, E35D, M36L, R41K, R57K, Q61D, I62V, L63P, T74S, L89IF
 RenG12409RenG12409KT743437PINAM46L, I54V, I84VN83DL10I, T12I, I13V, A22V, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, K70R, T74A, L89I, T91SF
 RenG12984RenG12984KT744012PINAM46I, I54V, V82A, I84V, L90ML33F, K43T, G73TL10V, L19V, K20R, E35D, M36I, R41N, D60E, Q61D, I62V, L63P, H69Y, A71T, I72TF
 RenG12524RenG12524KT743552PINAG48A, I54V, L76V, V82A, I84VV11VI, L24I, L33F, K43T, M46V, F53L, N83DL10Y, L19I, K20R, E35N, M36I, N37D, K55R, R57K, D60E, Q61N, I62V, L63P, H69Y, A71V, I72K, L89I, T91A, Q92KF
 RenG12374RenG12374KT743402PINAV32I, M46I, I54L, I84V, L90ML33F, L89VL10V, L19I, K20R, E35D, M36I, N37D, R41K, K55N, R57K, Q61N, A71V, Q92KF
 RenG12493RenG12493KT743521PINAM46L, I54V, V82A, I84VL24I, L33F, K43KTL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, I64L, E65D, A71L, I72T, T91S, I93LF
 RenG12539RenG12539KT743567PINAM46I, I54V, L76V, I84VN83DR8X, L10I, T12I, I13A, G16E, K20R, A22V, E35D, M36I, R41K, R57K, Q61N, I72R, L89IF
 RenG11600RenG11600KT742628PINAM46I, I54L, V82A, I84VL24I, L33FL10I, I13V, I15V, K20R, E35D, M36I, R41K, K43I, R57K, Q61N, I62V, I72T, I85V, L89M, T91SF
 RenG11441RenG11441KT742469PINAM46I, I54V, I84VL33LFL10I, T12N, I15V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, L63P, I72IT, L89T, I93LF
 RenG11279RenG11279KT742307PINAG48V, I54V, L76V, V82A, I84VM46V, Q58EL10I, I15V, G16E, K20R, E35D, M36I, K55R, R57K, Q61N, L63C, L89IF
 RenG10406RenG10406KT741434PINAV32I, M46I, I54V, V82A, I84V, L90ML33F, G73CL10V, T12N, I13V, G16A, L19P, K20R, E34Q, E35D, M36I, R41K, F53I, K55R, R57K, Q61N, L63P, A71T, Q92KF