<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I84V
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 40
Isolates 40
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Apetrei (2003)AC_Pat1RO.01.IS.01AY333463IDV, Unknown, SQV, NFVNAM46I, I54V, V82A, I84VL24I, K43T, G48W, F53LL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat26RO.01.IS.26AY333487IDV, RTV M46I, I54V, V82T, I84V L10V, I15V, E35D, M36I, R41K, K55R, R57K, L63T, E65D, I72V, T74S, L89MF
de Sa Filho (2003)BREPM022BREPM022AY182789IDV D30N, I84V L10I, G16E, P39S, K43R, R57K, Q61N, I64V, V77I, G86R, L89M, I93LF
Gomez-Carrillo (2004)9386793867AY365491PINAM46I, V82A, I84V Q7QH, L10I, T12TP, I15V, K20R, E35D, M36I, N37D, R41K, K43KN, R57K, Q61N, L63S, E65D, T74S, I93LF
 9629696296AY365523PINAI54V, V82AG, I84V, L90ML33F, Q58EQ7QH, L10I, T12TP, I13IV, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, A71V, I72RF
 100799100799AY365620PINAM46I, I54V, I84VN83DL10IV, I13V, I15V, E35D, M36I, N37DE, R41K, R57K, Q61N, L63S, I64VF
 102008102008AY365649PINAM46I, I84V L10I, I15V, K20T, E35D, M36I, R41K, R57K, Q61D, E65D, I72TF
 106151106151AY365743PINAI84V, L90MG73SI15V, K20M, E35D, M36I, R41K, R57K, Q61D, A71V, I72R, I93LF
 107559107559AY365770PINAM46L, I54V, V82A, I84VL24IL10I, I15V, G17E, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, I62V, L63P, I64V, A71VF
 109072109072AY365802PINAM46I, I84V, L90M L10I, I13V, I15V, Q18H, L19I, K20I, E35D, M36I, N37K, R41K, R57K, D60DE, Q61N, L63P, G68E, A71T, I72EF
 115855115855AY365925PINAM46ML, I54AV, I84V, L90MV11I, L89VL10I, I13V, G17E, K20V, E35D, M36I, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
 118746118746AY365953PINAM46I, I54V, I84V, L90MV11I, G73SL10I, I15V, L19P, K20I, E35D, M36I, R57K, Q61H, L63P, A71V, I72T, I85V, I93LF
de Sa Filho (2005)BREPM107BREPM107AY771588PINAI84V, L90M I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71VF
Baxter (2006)48-11671167-30903DQ877354PINAI54V, I84V, L90MG73TL10I, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63P, I85IVF
 48-62856285-30924DQ878833PINAI54V, V82T, I84V T4TS, L10V, I13V, I15V, Q18M, L19Q, K20R, E35D, M36I, N37D, R41K, Q61N, A71V, L89IF
Dumans (2009)RES165_03RES165_03FJ405046SQV126I84V L10V, I15V, E35D, M36I, R41K, R57K, Q61D, H69Y, I72K, T74SF
 RENA332RENA332FJ405177IDV, SQV, RTV, NFV291I84V, L90M L10V, K20R, E35D, M36I, R41K, D60E, Q61D, I62V, L63P, H69Y, I72T, L89MF
Aulicino (2011)ARM53NBEARM53NBEFJ525823PINAV32I, I84V, L90MG73SI15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, A71VF
Jones (2012)130542130542JN669493PINAI54V, V82A, I84VF53LT4TS, L10V, T12E, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, A71V, T74S, I85V, L89IF
 136173136173JN669555PINAI54V, I84V, L90M K14R, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71T, I72TF
 142709142709JN669620PINAM46I, I54V, V82A, I84V, L90ML33F, Q58QEL10I, I15V, G17D, K20T, E35D, M36I, R41RK, R57RK, D60E, Q61D, L63P, A71V, I93LF
 143569143569JN669642PINAM46I, I84V, L90ML10LFI, G73ST12M, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61D, I62V, I72K, I93LF
 149342149342JN669733PINAI84V, L90MN83DL10I, L19LI, K20R, E35D, M36I, N37ND, R41K, K45R, R57K, Q61N, I62IV, L63P, I64LF
 151726151726JN669766PINAI54A, I84V, L90MV11I, G73GDNS, L89VL10I, T12TP, I13V, G17E, K20V, E35D, M36I, N37NDEK, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
 162512162512JN670040PINAM46I, I54V, V82S, I84V L10LV, I15V, G16E, K20R, E34A, E35D, M36I, R41K, K43I, K55R, R57K, D60DN, Q61DN, L63C, L89LMF
 162645162645JN670045PINAI54V, V82A, I84V, L90ML23I, Q58EL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63C, I64V, A71V, V77I, I93LF
 166335166335JN670126PINAI54M, I84VL33FI15V, E34D, E35D, M36I, R41K, R57K, Q61N, V82IF
 166999166999JN670141PINAI47A, I84V I15V, E35D, M36I, R41K, R57K, Q61N, A71AV, L89M, I93LF
 169081169081JN670190PINAM46L, G48V, I54V, V82S, I84V L10V, I15V, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63C, A71V, I72V, T74S, I93LF
 172771172771JN670300PINAI54A, I84V L10I, I13V, I15V, L19I, K20R, E34N, E35D, M36I, R41K, R57K, Q61N, L63P, A71T, I72T, I93LF
 175785175785JN670372PINAI84V, L90ML10LF, G73GSI15V, K20MV, E35D, M36I, R57K, D60E, Q61D, A71V, I72TF
 177489177489JN670445PINAI54V, V82T, I84VL33IL10V, I13V, I15V, K20R, E34ED, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, I64V, A71V, T74S, P79A, I85V, I93LF
 184896184896JN670689PINAM46I, I54V, V82T, I84V, L90ML33F, Q58EL10V, I13V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P, A71V, I85V, L89M, I93LF
 193990193990JN670919PINAM46L, I54V, V82A, I84VL24I, L33FL10I, I13V, I15V, K20M, E35D, M36I, R57K, Q61N, L63P, A71V, I72T, I93LF
 196067196067JN671012PINAV32I, M46MI, I54IL, I84V, L90MF53LL10I, T12N, I15V, L19I, K20R, E35D, M36I, N37NS, R41K, R57K, Q61D, L63T, I66IV, A71L, I72T, V77VI, I93LF
 200121200121JN671191PINAM46I, I54V, V82T, I84VL33F, G73SL10V, I13V, K14R, I15V, Q18L, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, A71AT, I72T, T74TI, I93LF
 205791205791JN671372PINAI54V, I84V, L90M L10I, I13IV, I15V, Q18K, K20M, E35D, M36I, R41K, Q61N, I62V, L63P, I66IV, T74A, L89IF
 206165206165JN671393PINAM46L, I54V, I84VL24I, K43T, F53LL10I, I15V, G17D, K20T, E35N, M36I, K55R, Q61N, L63T, E65D, A71V, I72T, T74E, V82I, L89M, I93LF
 206318206318JN671397PINAM46L, I54V, V82A, I84VV11I, L24I, L33LF, K43TL10I, I15V, G16E, L19I, K20R, E35D, M36IV, K55R, R57K, Q61N, L63N, A71T, I72T, T91SF
 207640207640JN671442PINAM46L, G48AEKT, I54V, V82M, I84VL24I, L33I, K43T, F53FLL10I, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63IT, E65D, I72T, T74S, P79PS, L89MF