<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation V82I
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 49
Isolates 50
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Masciotra (2000)SM31SM31AF221044PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63G, V82I, T96SF
Apetrei (2003)AC_Pat6RO.00.IS.06AY333525IDV, RTV, NFV   I15V, L19I, E35D, M36I, R41K, R57K, I62V, L63T, E65D, V82I, L89M, I93LF
  RO.01.IS.06AY333526IDV, RTV, NFV, UnknownNA  L10V, I15V, L19I, K20T, E35D, M36I, R41K, R57K, I62V, L63T, E65D, V82I, L89M, I93L, F99YF
 AC_Pat47RO.00.IS.47AY333457IDV   T12S, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, V82I, L89MF
Dumans (2004)F136F136AY390083NFV, Unknown>108  T12Q, I15V, E35D, M36I, R41K, R57K, Q61D, L63Q, K70T, V82I, L89MF
 RES075RES075AY390202IDV, SQV, NFV, RTV, APV, Unknown>317I54IV L10V, I13V, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63LP, T74TA, V82I, I85V, L89M, I93ILF
Gomez-Carrillo (2004)115855115855AY365925PINAM46ML, I54AV, I84V, L90MV11I, L89VL10I, I13V, G17E, K20V, E35D, M36I, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
Rodrigues (2005)BLF_Pat31BR03SP35AY643173NFV, RTV33  T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63V, V82I, L89MF
Rios (2007)CH2MR_CH2EF193885Unknown, IDVNA  T12K, I15V, E35D, M36I, R41K, R57K, Q61S, C67W, V82I, L89MF
Waleria-Aleixo (2008)08PR06065608PR060656FJ591511PINAL90LM K14R, I15V, Q18M, E35D, M36I, R41K, R57K, Q61N, L63A, V82I, T96TNF
 08RJ04012508RJ040125FJ591608PINA  I15V, E35D, M36I, R41K, R57K, D60E, Q61S, I62V, L63P, V82I, L89MF
 08PR04013508PR040135FJ591184PINAV32I, I47V, L90M T12S, K14R, I15V, K20T, E35D, M36I, R41K, K55KR, R57K, D60E, Q61N, L63P, A71T, I72T, V82I, L89I, I93LF
 02PE06084102PE060841FJ591168PINAI54V, L90M I13V, I15V, G16Q, K20R, E35D, M36I, N37E, P39S, R41K, R57K, D60E, Q61N, V82I, L89MF
 08PR05023608PR050236FJ591265PINAI54V, L76V, I84V, L90M L10I, I15V, G16GA, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, L63LP, A71V, P79S, V82I, L89I, Q92K, I93LF
Aulicino (2011)ARN815QLSARN815QLSFJ525866PINAI54V, L90M I13V, I15V, K20T, E35D, M36I, P39Q, R57K, Q61N, L63P, A71T, V82I, L89I, Q92K, I93LF
Jones (2012)151726151726JN669766PINAI54A, I84V, L90MV11I, G73GDNS, L89VL10I, T12TP, I13V, G17E, K20V, E35D, M36I, N37NDEK, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
 160560160560JN669981PINAM46I, I54V, L76V, L90ML89VL10V, I13V, I15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 182090182090JN670599PINAM46I, I54V, L76VL89VK20P, E35N, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 195201195201JN670970PINAD30N, I54VI47ML10I, K20T, E35N, M36I, N37D, K45A, V56A, R57K, Q61N, I62V, L63P, V77I, V82I, N88E, L89MF
Kouri (2012)CU263-10CU263-10JQ585374PINAV32I, I54M, I84VV11I, L33F, F53FLQ2L, L5LF, L10V, I13V, K14E, I15V, G17D, K20R, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, L63P, I64V, A71V, T74E, V82IF
Diaz (2015)RenG17168RenG17168KT748196PINAV32I, I47A, I50VN83NDL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, V82I, I85V, L89IF
 RenG17135RenG17135KT748163PINAI50LG73ST12K, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, L63P, I64V, V75I, V77I, V82I, I93LF
 RenG16900RenG16900KT747928PINAM46I, I54VN88G, L89VL10I, I13V, I15V, K20T, E35D, M36I, N37ND, R41K, R57K, Q61N, L63P, I72T, V82IF
 RenG15854RenG15854KT746882PINA  I15V, L19T, E35D, M36I, N37D, R41K, R57K, Q61S, I62V, L63P, I64L, H69HY, I72M, V82IF
 RenG15580RenG15580KT746608PINA  T12S, I15V, L19IV, K20R, E35D, M36I, R41K, L63T, I72T, V82IF
 RenG16671RenG16671KT747699PINA  K14R, I15V, E35D, M36I, R41K, R57K, Q61N, I62V, I72IV, T74S, V82I, L89MF
 RenG16557RenG16557KT747585PINA  K14R, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, V82I, L89MF
 RenG16312RenG16312KT747340PINAM46L, I47A, L90M I13V, I15V, K20MT, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71T, I72T, V82I, L89I, I93LF
 RenG17240RenG17240KT748268PINAV32I, M46I, I47V, I54M, L90ML33F, F53L, L89VL10I, I13V, I15V, L19V, K20R, E35D, M36I, N37DE, R41K, G51A, R57K, Q61N, I66F, A71V, G73N, V77I, V82IF
 RenG13731RenG13731KT744759PINA  T12N, I15V, E35D, M36I, R41K, R57K, Q61N, E65D, V82I, L89MF
 RenG14297RenG14297KT745325PINA  E35Q, M36MI, N37E, R41K, R57K, Q61N, I64V, V77I, V82IF
 RenG15093RenG15093KT746121PINA  T4TIN, I15V, L19T, E35D, M36I, N37D, R41K, R57K, Q61S, I62V, L63P, I64L, H69HY, I72M, V82IF
 RenG14425RenG14425KT745453PINAV32I, I47A, L90M L10I, I13V, L19I, E35D, M36I, N37E, K43R, R57K, Q61N, L63P, V82I, L89IF
 RenG13781RenG13781KT744809PINAM46I, I50V, I54V, L76V L10I, I15V, K20T, E35N, M36I, R41K, R57K, Q61D, I62V, L63V, I64IV, A71V, T74A, V82I, L89M, I93LF
 RenG14620RenG14620KT745648PINAL90MF53L, G73SI13V, I15V, K20T, E35D, M36I, N37T, R41K, R57K, D60E, Q61E, I62V, L63P, A71I, V82I, I93LF
 RenG14052RenG14052KT745080PINA  I15V, P39S, R41K, R57K, Q61N, L63P, I64L, V82IF
 RenG13393RenG13393KT744421PINAD30NL33F, F53L, N88DI15V, L19Q, K20T, E35D, M36I, N37NT, R41K, K45I, R57K, D60E, Q61E, I62V, L63P, I66F, A71V, T74S, V77I, V82I, L89T, Q92RF
 RenG12742RenG12742KT743770PINA  E35D, M36MI, P39PS, R57K, Q61D, I72IT, V77I, V82I, L89MF
 RenG12504RenG12504KT743532PINAI50L T12I, G17E, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, I64V, V82I, L89MF
 RenG12103RenG12103KT743131PINA  T12P, K14R, E35D, M36I, R41K, K45R, R57K, D60E, Q61D, C67H, V82I, L89MF
 RenG12818RenG12818KT743846PINAV32I, I47AV, I50L I15V, K20T, E35D, M36I, R41K, R57K, Q61S, K70R, A71V, V82I, I85V, L89IF
 RenG12672RenG12672KT743700PINAV32I, I47A L10V, I13V, G16E, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63S, A71AT, I72E, V82I, L89IF
 RenG11095RenG11095KT742123PINA  I15V, E35D, M36I, R41K, R57K, Q61N, E65D, I72T, V82I, L89LMF
 RenG11077RenG11077KT742105PINA  I15V, G16E, K20R, E35N, M36I, P39Q, R41K, R57K, Q61N, E65D, I72T, V82I, R87RI, L89MF
 RenG10958RenG10958KT741986PINAM46MI, I50IVL33LFI15V, K20KT, E35D, M36I, R41K, R57K, D60E, Q61S, I62V, L63P, V82I, L89IMF
 RenG11402RenG11402KT742430PINA  T12N, I15V, L19I, N37E, Q61N, L63S, P79S, V82I, L89IF
 RenG10324RenG10324KT741352PINAV32I, I47A L10I, T12S, I15V, L19I, K20T, E35D, M36I, N37S, R41N, R57K, Q61DN, L63V, H69HY, I72T, V82I, L89M, I93LF
 RenG11343RenG11343KT742371PINAI50LQ58QE, G73ST12K, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, L63P, I64V, V75VI, V77I, V82I, I93LF
 RenG10230RenG10230KT741258PINAM46I, I50IVL33FI13IL, I15V, K20T, E35D, M36I, N37NHKQ, R41K, R57K, D60E, Q61NS, I62V, L63P, V82I, L89MF
 RenG10740RenG10740KT741768PINA  E35D, M36I, R41K, R57K, Q61N, I64IMV, I72T, V77I, V82IF