<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation V77I
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 211
Isolates 211
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Brindeiro (2002)TVSP24TVSP24AY145818RTV, NFV, Unknown>2  G17S, Q18L, N37E, R57K, L63P, V77I, I93LF
de Sa Filho (2003)BREPM022BREPM022AY182789IDV D30N, I84V L10I, G16E, P39S, K43R, R57K, Q61N, I64V, V77I, G86R, L89M, I93LF
Dumans (2004)RG046RG046AY390209RTV, NFV189M46ML, I54V, L90M L10V, I15IV, K20R, E35D, M36V, N37E, R57K, D60E, Q61DN, I62V, L63LP, A71V, I72T, V77I, I93LF
 223223AY390043NFV13  G16E, E35D, R41K, K70R, V77IF
 242242AY390086NFV177D30N, M46IN88DL10V, I13V, R41K, R57K, D60E, Q61D, I64V, V77I, I85VF
 245245AY390088NFV173  I15V, E35D, M36I, N37A, R41K, K45Q, R57K, D60E, Q61N, V77IF
Gomez-Carrillo (2004)9488394883AY365506PINA G73ST12TP, I13V, I15V, E35D, M36I, R41K, K43KN, R57KN, Q61N, L63P, V77I, I93LF
 9764497644AY365553PINAV32I, M46I, I47V, V82AL24I, L89VL10I, T12N, I15V, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, A71T, V77I, I93LF
 9821698216AY365570PINAL90M I13IV, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, V77I, I93LF
 9883998839AY365584PINA  I15V, E35D, M36I, R41K, Q61N, V77IF
 102998102998AY365663PINAG48V, I54V, V82S L10V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, H69HY, A71V, V77I, I93LF
 103278103278AY365675PINA  I15V, E35D, M36I, N37D, R41K, R57K, Q61N, V77I, I93LF
 106958106958AY365758PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, I93LF
 108506108506AY365789PINA  L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, I72E, V77I, I93LF
 108517108517AY365790PINA  L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, I72E, V77I, I93LF
 109089109089AY365804PINAI54V, V82A, L90MK43T, F53LL10I, L19I, K20R, E35D, M36I, R41K, Q61N, L63T, E65D, C67E, A71V, I72T, T74S, V77I, I93IMF
 109988109988AY365828PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63S, I72T, V77I, I93LF
 114305114305AY365896PINAD30NQ58E, N88DL10I, I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, I72V, V77I, I93LF
 117084117084AY365936PINA  E35D, M36I, R41K, R57K, Q61N, V77I, I93ILF
Thomson (2004)99UFRJ_199UFRJ_1AY455778NFV39  E35D, M36I, R41K, R57K, D60E, Q61D, V77I, L89MF
Rodrigues (2005)BLF_Pat3BR02SP249AY643146Unknown, NFV>74N88S K20T, E35D, M36I, R41K, R57K, Q61N, V77I, L89MF
 BLF_Pat30BR03SP179AY643165IDV, RTV, Unknown, APV, LPV, NFV>152  L10V, I13IV, E35D, M36I, R41K, R57K, D60E, Q61N, I72IT, V77I, L89MF
 BLF_Pat40BR02SP226AY643142NFV148N88S L10I, I13V, I15IV, K20T, E35D, M36I, R41K, R57K, Q61N, E65D, V77I, L89MF
 BLF_Pat42BR02SP154AY643138RTV, Unknown, NFV>70L90M T12R, I15V, L19S, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, T74S, V77I, L89M, I93ILF
Baxter (2006)48-10741074-30626DQ877334PINAV32I, M46I, I47V, I54V, V82A, L90LML24I, L33F, T74PSL10I, I13IV, I15IV, G16E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63S, E65D, A71AV, V77I, L89M, Q92QK, I93LF
 48-10731073-30626DQ877335PINAI54A, V82F L10I, I13IV, L19V, K20R, E35D, M36I, N37H, R41K, K45T, F53C, K55T, Q61D, I62IV, L63T, I64M, A71V, I72T, V77I, I93LF
 48-11101110-30701DQ877398PINAM46I, I54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71V, I72T, V77I, I93LF
 48-32663266-30729DQ878171PINAM46I, I54V, V82AV11VI, L24I, L33F, L89VL10I, I15V, K20A, E35DN, M36L, N37Q, R41K, K55R, R57RK, D60E, Q61E, I62V, L63P, I64L, A71V, I72M, V77I, T91S, I93LF
 48-91519151-30826DQ877716PINAM46FL, I54V, V82A, L90M L10I, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, D60E, Q61N, L63P, H69Y, A71V, I72T, V77I, L89M, I93LF
Santos (2006)128128PR_RTAY275769Unknown, RTV, SQV, IDV>205  I15V, R57K, Q61N, L63P, C67S, I72T, V77IF
Dumans (2009)108PR108PRFJ405037NFV, Unknown>26D30NN88DI15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, A71V, V77I, I93LF
 RENA101RENA101FJ405038NFV78 N88DV11VF, I15V, K20T, E35D, M36I, R41K, R57K, Q61D, I72V, V77I, L89MF
 RENA389RENA389FJ405040NFV30  E35D, M36I, R41K, K45R, R57K, Q61N, L63P, V77I, L89M, I93LF
 RES327_03RES327_03FJ405050RTV, NFV100  I13V, E35D, M36I, R41K, R57K, D60E, Q61E, L63P, V77I, L89MF
 RENA654RENA654FJ405122RTV, NFV, LPV356M46L, I54V, V82A, L90M L10V, I15V, K20R, E35D, M36V, N37E, R57K, D60E, Q61D, I62V, A71V, I72T, V77I, I93LF
 RENA162RENA162FJ405125SQV, NFV, IDV260  L10I, E35D, M36I, R41K, D60E, Q61N, I62V, L63T, C67D, T74S, V77I, L89MF
Sanabani (2009)57906BR579FJ771009PINA  L10P, G16E, E35D, M36I, R41K, D60E, Q61N, I62V, V77I, L89MF
Aulicino (2011)ARM640RCAARM640RCAFJ525835PINAD30NN88DL10V, T12I, I15V, G16E, E35D, M36V, N37E, R41K, K45R, R57K, Q61N, L63T, I72T, V77I, I93LF
 ARN204SBDARN204SBDFJ525854PINAM46MI, I47IV, I54V, V82F, L90MQ58EL10IV, I15V, G17D, K20T, E35N, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, I72R, V77I, I93LF
 ARN311BMSARN311BMSFJ525857PINAM46L, G48Q, I54V, L76V, V82A, L90MV32L, F53L, Q58EL10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, A71V, T74S, V77I, I93LF
 3343-N414ML3343-N414MLHQ158158PINAD30NN88DL10I, I15V, K20T, E35N, M36I, R41K, R57K, D60E, Q61D, L63P, V77I, I93LF
 3225-O153AGL3225-O153AGLHQ158161PINAD30N, L90MN88DT12A, K14R, K20T, E35D, M36I, N37D, R41N, R57K, Q61N, L63P, T74S, V77I, I93LF
 2057-L631ADS2057-L631ADSHQ158272PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, I93LF
Jones (2012)137091137091JN669559PINAI54V, V82VA, L90M L10I, K20KR, E35D, M36I, R41K, Q61N, L63T, A71V, I72T, V77I, I93LF
 140218140218JN669583PINAG48V, I54V, V82SK43TL10V, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63P, H69Y, A71V, V77I, I93LF
 143095143095JN669636PINAM46L, I54V, V82AL33FL10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, V77I, T91S, I93LF
 156156156156JN669852PINA  I15V, E35D, M36I, R41K, R57K, Q61D, I62IV, V77I, I93LF
 157769157769JN669899PINA  T12V, I15V, E35D, M36MI, N37D, R41K, R57K, Q61N, V77I, I93LF
 159810159810JN669966PINAI54S, V82A, L90ML33F, K43TL10I, I13V, I15V, G16E, L19I, K20R, E34R, E35D, M36I, N37T, R41K, R57K, Q61D, A71IL, I72R, V77I, I93LF
 160102160102JN669969PINA  I15V, K20KR, M36MI, R41K, R57K, Q61N, A71T, I72EV, V77I, I93LF
 161429161429JN670008PINA  I15V, E35D, M36I, R41K, R57K, Q61N, V77IF
 162645162645JN670045PINAI54V, V82A, I84V, L90ML23I, Q58EL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63C, I64V, A71V, V77I, I93LF
 163933163933JN670073PINAM46I, I47V, I54V, V82F, L90ML89VL10I, I15V, G17D, K20T, E35N, M36I, R41K, K55KR, R57K, Q61N, I62V, L63P, T74S, V77I, I85V, I93LF
 164954164954JN670089PINA  I15V, E35D, M36I, R41K, R57K, Q61N, I72V, V77I, I93LF
 165724165724JN670114PINAD30NN88DI15IV, K20T, E35N, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, I64L, A71AV, V77I, I93LF
 167151167151JN670145PINAI54L, L90M L10V, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63C, E65D, I72T, V77I, I93LF
 168544168544JN670182PINAM46L, V82A T12TP, L19LQ, E35D, M36I, R41K, R57K, Q61D, L63P, V77I, I93LF
 170484170484JN670222PINA  E35D, M36I, N37D, R41RK, Q61N, V77IF
 177362177362JN670438PINA  T12I, I15V, E35D, M36I, N37D, R57K, Q61S, I62V, A71T, V77I, I93LF
 178225178225JN670477PINAD30N I15V, K20T, E35D, M36I, N37NT, R41K, R57K, Q61N, L63LP, V77I, I93LF
 179184179184JN670503PINAI54IV, V82VF, L90LML89LVR8R*, L10LI, I15V, K20KT, E35DN, M36I, N37D, R41K, R57K, Q61DN, L63LP, I64IV, T74TS, V77I, I85IV, I93LF
 179613179613JN670518PINAI54V, V82A, L90MF53LL10I, I15V, G16E, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63T, E65D, I72T, V77IF
 179672179672JN670523PINAD30N, L90LMN88DL10I, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, L63P, E65ED, K70R, V77I, I93LF
 180532180532JN670549PINA  T4TA, I15V, E35D, M36I, N37NY, R41K, V56VI, R57K, Q61N, L63G, H69Q, V77IF
 180609180609JN670551PINA  I15V, R41K, R57K, Q61N, A71T, I72E, V77I, I93LF
 181927181927JN670593PINA  E35D, M36I, R41K, R57K, D60E, Q61D, I62V, V77I, I93LF
 183117183117JN670638PINA  L10V, I15V, E35D, M36I, R41K, R57RK, Q61D, V77I, I93LF
 184561184561JN670682PINA  I13V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, I93LF
 184986184986JN670691PINA  T12P, K14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, I64V, H69Y, V77I, I93LF
 187706187706JN670737PINA  I15V, Q18E, E35D, M36I, R41K, R57K, Q61N, L63T, V77I, I93LF
 187820187820JN670742PINAI50IL, V82VA, N88NSL10LFII15IV, K20T, E35DN, M36I, N37ND, R41K, R57K, Q61N, L63P, A71AITV, T74S, V77I, L89LMF
 192094192094JN670846PINAI54L, N88S L10V, T12R, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, T74S, V77I, I93LF
 192895192895JN670872PINA  I15V, E35D, M36I, R41K, R57K, Q61D, I72KR, V77IF
 192902192902JN670873PINA  L10LI, K14R, I15V, L19I, E35D, M36I, N37D, R41K, R57K, D60DE, Q61DN, I62IV, L63AP, I64IL, V77I, I93LF
 195201195201JN670970PINAD30N, I54VI47ML10I, K20T, E35N, M36I, N37D, K45A, V56A, R57K, Q61N, I62V, L63P, V77I, V82I, N88E, L89MF
 195702195702JN670997PINA  I3N, L10LI, I15IV, G16E, K20KM, E35D, M36MI, R41K, R57K, Q61N, L63G, V77I, I93LF
 196945196945JN671045PINA  L10V, I15V, E35D, M36I, R41K, R57K, Q61N, I72T, V77IF
 197833197833JN671086PINAL90M L10V, I13V, I15V, K20T, E35DN, M36I, P39Q, R57K, D60E, Q61D, L63P, A71AV, V77I, I93LF
 198179198179JN671108PINA  Q2QH, I3HLQ, L5LHQ, W6WCRS, R8RQ, T12S, I15V, K20KR, R41K, R57K, Q61N, V77I, I93LF
 198466198466JN671120PINAL90M I15V, K20T, E35G, M36I, R41K, R57K, Q61N, I62V, L63P, I72IV, T74S, V77I, I93LF
 199190199190JN671152PINA  T12A, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, I93LF
 199882199882JN671185PINAM46L, I54V, V82AL24I, Q58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, V77IF
 202696202696JN671286PINA  L10I, T12P, E35D, M36I, N37D, R41K, R57K, D60E, Q61D, L63S, E65D, A71T, I72IT, V77I, I93LF
Diaz (2015)RenG16086RenG16086KT747114PINAD30NQ58E, N88DK20T, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, L89MF
 RenG17130RenG17130KT748158PINA  L10V, I15V, E35D, M36I, P39T, R41K, D60E, Q61N, V77I, L89MF
 RenG15730RenG15730KT746758PINA  I13V, I15IV, Q18QL, E35D, M36I, R41K, R57K, Q61N, V77I, L89MF
 RenG17077RenG17077KT748105PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41PQ, R57K, Q61N, I62V, L63P, A71I, V77I, L89TF
 RenG16077RenG16077KT747105PINA  L10V, K14R, I15V, Q18M, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, L63LP, I72IV, V77I, L89M, I93LF
 RenG17405RenG17405KT748433PINA  L10I, I15V, G16E, E35D, M36I, R41K, R57K, D60E, Q61N, L63C, V77I, L89M, I93LF
 RenG16905RenG16905KT747933PINA  L10LIV, I15IV, G16GE, E35D, M36I, P39T, R41RK, D60E, Q61N, L63LP, V77I, L89M, I93LF
 RenG17347RenG17347KT748375PINAL90M L10V, T12I, I15V, G16Q, K20T, E35D, M36I, P39Q, R41K, K45R, R57K, Q61N, A71V, I72T, V77I, I85V, L89T, I93LF
 RenG17135RenG17135KT748163PINAI50LG73ST12K, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, L63P, I64V, V75I, V77I, V82I, I93LF
 RenG15615RenG15615KT746643PINA  T12K, L19S, E35D, M36I, N37D, R41K, R57K, D60E, Q61D, L63LP, H69HY, V77I, L89MF
 RenG15941RenG15941KT746969PINAI54IV, I84IVQ58EL10LI, T12TA, Q18QE, L19LI, K20KR, E35D, M36I, R41RK, R57RK, D60E, Q61N, L63PT, V77I, L89MF
 RenG16827RenG16827KT747855PINAI54V, V82F, I84VF53LL10V, I15V, G16E, K20T, E35D, M36I, P39Q, R41K, K45V, R57K, D60E, Q61D, I72R, T74A, V77I, L89MF
 RenG15564RenG15564KT746592PINA  L10I, T12A, I13V, E35D, M36I, R41K, R57K, Q61N, I64V, V77IF
 RenG17089RenG17089KT748117PINA  K14R, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, L89MF
 RenG16414RenG16414KT747442PINAL90ML23I, F53LL10V, K14R, I15V, K20T, E35D, M36I, N37ST, R41K, R57K, Q61D, I62IV, L63P, A71AV, I72IL, T74S, V77I, I93LF
 RenG17309RenG17309KT748337PINAM46I, I50V, V82A, L90ML33F, K43T, F53LL10V, G16E, K20R, E34N, E35D, M36I, P39S, R41K, K55R, R57K, D60E, Q61D, L63HP, A71I, V77I, L89M, I93LF
 RenG17059RenG17059KT748087PINA  L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63T, I72T, T74S, V77IF
 RenG17442RenG17442KT748470PINAM46I, I47V, I54V, V82F, L90MK43TL10I, I13V, K14R, I15V, K20T, E35N, M36I, R41K, R57K, D60E, Q61D, I72T, V77I, L89IF
 RenG17332RenG17332KT748360PINAV32I, M46L, I47V, V82FF53LL10I, K20R, E35D, M36I, N37S, R41K, R57K, Q61N, L63T, E65D, A71I, I72T, V77I, I85V, I93LF
 RenG16459RenG16459KT747487PINAM46I, I54V, V82F, L90ML33I, K43TL10V, I13V, K20T, E35D, M36L, N37D, R41K, F53Y, R57K, Q61N, I62V, L63P, T74S, V77I, L89I, I93LF
 RenG15848RenG15848KT746876PINAI54L, N88SK43KTL10V, T12TK, K14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61N, L63T, I64V, V77I, L89M, I93LF
 RenG16032RenG16032KT747060PINA  T12K, I15V, E35D, M36I, R41K, R57K, Q61N, V77I, L89M, I93ILF
 RenG16812RenG16812KT747840PINA  L10I, E35D, M36I, R41K, R57K, D60E, Q61D, L63S, I72T, V77I, L89M, I93LF
 RenG17060RenG17060KT748088PINA  E35D, M36I, R41K, R57K, Q61H, L63AS, I72IV, V77I, L89MF
 RenG16180RenG16180KT747208PINA F53L, G73SL10V, I13V, I15V, K20T, E35D, M36I, N37T, R41K, K55HN, R57K, Q61N, L63P, A71T, T74S, V77I, Q92KF
 RenG16636RenG16636KT747664PINA  L10LV, I15V, E35D, M36I, N37D, R41K, R57K, Q61N, L63LAPV, I64IL, K70KR, I72IT, V77I, L89LIM, Q92QK, I93ILF
 RenG15659RenG15659KT746687PINAI50L K20R, E35D, M36I, R41K, R57K, D60E, Q61DN, L63P, H69HR, A71AV, V77I, L89M, I93LF
 RenG17438RenG17438KT748466PINAD30N, M46I, I50L, L90MK43T, N88DI13V, K14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61D, I62V, L63P, A71V, V77I, I85IVF
 RenG17429RenG17429KT748457PINAI50L K14R, I15V, K20T, E35D, M36I, N37T, R41K, K45R, R57K, D60DE, Q61N, H69I, A71T, I72T, V77I, I93ILF
 RenG17240RenG17240KT748268PINAV32I, M46I, I47V, I54M, L90ML33F, F53L, L89VL10I, I13V, I15V, L19V, K20R, E35D, M36I, N37DE, R41K, G51A, R57K, Q61N, I66F, A71V, G73N, V77I, V82IF
 RenG16325RenG16325KT747353PINA  K14KR, I15L, Q18QK, K20M, E35D, M36I, R41K, R57K, Q61N, V77IF
 RenG16849RenG16849KT747877PINAM46IF53L, N88TL10V, I15IV, G16E, L19I, K20T, E35D, M36V, N37T, P39T, R41I, K45Q, R57K, D60DE, Q61N, I62V, L63A, E65D, V77I, L89MF
 RenG16348RenG16348KT747376PINA  E35D, M36I, R41K, R57K, D60E, Q61D, L63P, I72T, V77I, L89MF
 RenG16844RenG16844KT747872PINAD30N, M46I, I50L, L90MK43T, N88DI13V, K14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61D, I62V, L63P, A71V, V77I, I85IVF
 RenG14038RenG14038KT745066PINA  I15V, K20T, E35N, M36I, R41K, R57K, Q61N, L63P, T74S, V77I, I85IVF
 RenG14507RenG14507KT745535PINAM46I, I47V, I54V, V82AF53L, Q58EL10V, K14R, G17E, L19V, K20R, E35D, M36I, N37D, R41RK, K55R, R57K, Q61N, L63T, E65D, I72T, V77I, L89MF
 RenG14257RenG14257KT745285PINAG48EQ, L90MF53L, T74PST4S, L10V, I15V, G16Q, K20T, E35D, M36I, N37NADT, P39S, R41K, R57RK, D60E, Q61N, L63P, A71V, V77I, I93LF
 RenG13723RenG13723KT744751PINAI84IVF53FLI13V, I15V, K20KT, E35D, M36I, R41K, R57RK, D60E, Q61N, V77I, L89MF
 RenG13917RenG13917KT744945PINA  G16E, E35D, P39T, R41K, R57K, D60E, Q61N, V77I, L89MF
 RenG14713RenG14713KT745741PINAI54V, L90ML23IV, F53LL10V, K20R, E35D, M36I, N37T, R41K, R57K, D60E, Q61D, I62V, I64V, A71AV, I72R, V77I, L89M, I93L, C95CFF
 RenG14668RenG14668KT745696PINAD30N, I50L, V82A, L90ML33F, N88DI13V, I15V, K20R, E35D, M36I, R41K, K55N, R57K, Q61N, L63P, A71V, I72M, V77I, Q92QRF
 RenG14530RenG14530KT745558PINAI50L, V82AL33F, F53LL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, D60E, Q61DN, T74TA, V77I, L89MF
 RenG15361RenG15361KT746389PINAI50L W6G, G16GR, K20T, E21EG, E35D, M36I, R41K, K45R, R57K, Q61N, A71V, V77I, L89T, T96XF
 RenG15485RenG15485KT746513PINA  E35D, M36I, N37DE, R57K, D60E, Q61N, V77I, L89MF
 RenG15437RenG15437KT746465PINA  L10V, K20R, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, L63P, K70Q, I72V, V77I, P79A, L89MF
 RenG14543RenG14543KT745571PINA  E35D, M36I, R41K, R57K, Q61N, I64L, V77I, L89MF
 RenG14123RenG14123KT745151PINA  I15V, E35D, M36I, R41K, Q61N, L63P, E65D, V77I, L89MF
 RenG14109RenG14109KT745137PINA Q58EL10I, T12TI, I13V, E35D, M36I, R41K, K45KR, R57K, Q61N, L63AT, V77I, L89MF
 RenG15337RenG15337KT746365PINA  E35D, M36I, R41K, R57K, D60E, Q61D, L63P, V77I, L89MF
 RenG15176RenG15176KT746204PINAD30N, M46L, I50L, V82AL33FL10V, T12TM, I15V, G16E, K20R, E35D, M36V, P39S, R41K, K43Q, R57K, Q61N, L63T, I64V, E65D, A71V, I72T, V77I, I93LF
 RenG13655RenG13655KT744683PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41P, K55KR, R57K, Q61N, I62V, L63P, A71I, I72IV, V77I, L89TF
 RenG15184RenG15184KT746212PINA  L10P, T12S, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, E65D, K70R, V77I, L89MF
 RenG14743RenG14743KT745771PINA  L10I, G16E, E35D, M36I, P39T, R41K, R57K, D60E, Q61N, I62V, L63T, V77I, L89M, I93LF
 RenG14090RenG14090KT745118PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63Q, I64L, V77I, L89M, I93LF
 RenG13977RenG13977KT745005PINA  I13IV, E35D, M36I, N37D, R41K, R57K, Q61N, E65D, K70R, V77I, L89MF
 RenG14011RenG14011KT745039PINAI54L, L76V, V82FL33F, Q58EL10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, P39T, R41K, R57K, Q61N, A71V, I72R, V77I, L89IM, I93LF
 RenG14910RenG14910KT745938PINA  T12P, I13IMV, E35D, M36I, N37D, R41K, R57K, Q61N, L63LP, A71V, V77I, I93LF
 RenG14546RenG14546KT745574PINAL90M L10V, I15V, G16E, K20R, E35D, M36V, R41K, R57K, Q61N, I62V, L63T, I72T, V77I, L89M, I93LF
 RenG14680RenG14680KT745708PINA  L10V, I13IV, K14KR, I15V, E35D, M36I, R41K, R57K, Q61N, V77I, L89MF
 RenG14687RenG14687KT745715PINAI50L, N88SQ58EL10V, I15V, G16GE, K20T, E35D, M36I, R41K, R57K, Q61N, L63LP, T74TA, V77I, L89MF
 RenG14629RenG14629KT745657PINA  I15V, G16E, E35D, M36I, R41RK, R57K, D60DE, Q61D, I72R, V77I, L89MF
 RenG15132RenG15132KT746160PINAI84VL10FG16E, K20R, E35D, M36I, N37ND, R41RK, R57K, D60E, Q61D, I62V, I72T, V77I, L89MF
 RenG14318RenG14318KT745346PINA  E35D, M36I, R41K, K43KR, R57K, Q61HN, H69Q, V77I, L89MF
 RenG14069RenG14069KT745097PINAD30N, M46L, V82AL24I, L33F, K43TL10I, I15IV, G16E, K20R, E35D, M36V, N37T, P39S, R41K, R57K, Q61N, I62V, L63P, A71V, V75I, V77I, I93LF
 RenG14301RenG14301KT745329PINA  E35D, M36I, R41K, R57K, Q61N, E65D, V77I, L89MF
 RenG15399RenG15399KT746427PINA  K14R, I15V, L19I, E35D, M36I, R41K, R57K, Q61N, V77I, L89M, I93L, N98NIF
 RenG14222RenG14222KT745250PINAI54V, V82F, L90MQ58EL10I, I15L, G16A, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63C, A71V, I72T, V77I, L89M, I93LF
 RenG13959RenG13959KT744987PINAD30N, L90ML33LI, N88DL10Y, I15V, K20T, E35DN, M36I, N37D, R41K, R57K, Q61N, I62V, A71T, T74S, V77I, I85V, L89T, Q92QKRF
 RenG14439RenG14439KT745467PINA  I15V, K20V, E35D, M36I, R41K, R57K, D60E, Q61N, I62IV, L63LP, I72T, V77I, L89MF
 RenG13070RenG13070KT744098PINAD30N T12T*KS, I13V, K14R, I15AV, K20T, E35N, M36I, N37ND, R41K, K45Q, Q61N, L63T, I72T, V77IF
 RenG12882RenG12882KT743910PINAI54IV, V82VA L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, V77I, L89IMF
 RenG13393RenG13393KT744421PINAD30NL33F, F53L, N88DI15V, L19Q, K20T, E35D, M36I, N37NT, R41K, K45I, R57K, D60E, Q61E, I62V, L63P, I66F, A71V, T74S, V77I, V82I, L89T, Q92RF
 RenG13470RenG13470KT744498PINAM46I, I54V, L76V, V82A L10IV, I13IV, I15V, G16E, K20T, E35D, M36I, P39T, R41K, R57K, Q61N, L63T, E65D, I72V, T74S, V77I, L89MF
 RenG12914RenG12914KT743942PINAI50L, V82VA, N88SL33FL10I, T12AE, I13V, K14KT, I15IV, K20V, E35N, M36I, N37E, K45R, R57K, Q61N, L63P, I64V, K70T, A71V, V77I, L89M, Q92QKF
 RenG12397RenG12397KT743425PINA  W6GR, I15V, E35D, M36I, R41K, R57K, Q61N, L63T, I72T, T74S, V77I, L89MF
 RenG11837RenG11837KT742865PINA  K14R, I15V, Q18E, E35D, M36I, R41K, R57K, Q61N, H69Q, I72T, V77I, L89MF
 RenG12978RenG12978KT744006PINA  L10I, E35D, M36MI, R41K, R57K, D60E, Q61N, H69Q, I72V, V77I, L89MF
 RenG12816RenG12816KT743844PINA  E35D, M36I, R41K, R57K, D60E, Q61N, V77I, L89M, I93LF
 RenG13329RenG13329KT744357PINAN88SF53LG17E, L19I, K20T, E35D, M36I, N37T, R41K, R57K, Q61N, I62V, E65D, A71V, I72V, T74S, V77I, L89M, Q92KF
 RenG13203RenG13203KT744231PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63LP, I72IV, V77IF
 RenG11982RenG11982KT743010PINAD30N, M46I, I54V, L90MK43T, F53L, N88DL10R, I15V, K20T, E35D, M36I, R41K, K55KR, R57K, Q61N, I62IV, L63AV, A71V, T74S, V77I, Q92KF
 RenG12301RenG12301KT743329PINAD30N, I50LN88DT12N, I15V, L19I, K20T, E35D, M36I, N37T, R41K, K45R, Q61D, L63C, E65D, A71LV, V77IF
 RenG11986RenG11986KT743014PINAM46L, I54V, V82F, L90MF53LL10V, I15V, K20T, E35N, M36I, R41K, K55R, R57K, Q61N, I64V, G68E, A71V, V77I, I93LF
 RenG12449RenG12449KT743477PINAM46I, I54A, V82L, L90MQ58EL10I, K14R, I15V, G16Q, K20T, E35N, M36V, N37S, P39S, R41K, F53FY, R57K, D60E, Q61N, L63T, C67E, H69Y, A71V, I72T, V77I, I93LF
 RenG12506RenG12506KT743534PINA  L10I, E35D, M36I, R41K, Q61N, L63S, I72T, V77I, L89MF
 RenG13181RenG13181KT744209PINA  L10V, G16E, E35D, M36I, N37D, P39S, R57K, D60E, Q61N, I62V, L63S, I72V, V77I, L89MF
 RenG12174RenG12174KT743202PINAD30N, M46L, I54V, V82AL24I, L33FL10IV, I15V, G16E, K20R, E35D, M36V, P39S, R41K, K43Q, R57K, Q61N, L63T, I64V, E65D, A71V, I72T, V77I, Q92K, I93LF
 RenG12756RenG12756KT743784PINA  T12TK, I15V, G16E, K20M, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, L63X, I72E, V77I, L89M, I93LF
 RenG12458RenG12458KT743486PINAL90M L10V, G16E, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, E65ED, I72V, V77I, L89M, I93LF
 RenG12171RenG12171KT743199PINAM46L, I54V, V82AL24IL10I, I15IV, G16GR, K20R, E35D, M36I, N37DE, R41K, R57K, Q61N, L63A, A71V, T74S, V77I, I93LF
 RenG12577RenG12577KT743605PINAM46MI, I47IV, I54V, V82A, L90ML33F, K43KT, F53LL10V, K20R, E35D, M36I, R57K, D60E, Q61N, I62V, L63P, I64V, A71V, I72T, V77I, I93LF
 RenG11946RenG11946KT742974PINAM46L, N88SQ58EL10V, K20T, E35D, M36I, R57K, Q61N, I62V, L63S, E65D, I72T, V77I, L89M, I93LF
 RenG12929RenG12929KT743957PINAI54V, V82A L10V, K20R, E35D, M36I, N37E, R41K, K55R, R57K, D60E, Q61N, L63P, V77IF
 RenG12278RenG12278KT743306PINAD30NF53L, N88DL10V, I13V, I15V, K20T, E35D, M36I, Q61N, A71V, T74S, V77I, L89T, Q92RF
 RenG12368RenG12368KT743396PINAM46I, I54V, L76VG73SL10V, I15V, L19V, E35D, M36I, R41K, R57K, D60E, I62L, A71IV, V77I, I85V, L89T, Q92KF
 RenG13067RenG13067KT744095PINAV32I, M46L, I47A, L90M I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, I64IM, I72V, V77I, V82I, L89I, I93LF
 RenG13089RenG13089KT744117PINAM46I, I54V, L76V, V82L L10I, T12N, I15V, L19I, K20T, D25DN, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71I, V77I, I85V, L89T, Q92KF
 RenG13452RenG13452KT744480PINA  I15IV, E35D, M36I, R41K, R57K, D60E, Q61DN, C67CS, V77I, L89MF
 RenG12889RenG12889KT743917PINA  T12A, I15V, L19I, E35D, M36I, R41K, R57K, Q61DN, L63A, E65ED, I72E, V77IF
 RenG12096RenG12096KT743124PINAI50L, V82ML33LF, F53LT12TM, G16E, K20T, E35DN, M36I, N37NT, P39S, R41K, R57K, D60E, Q61DN, L63C, I72V, T74TA, V77I, L89MF
 RenG10803RenG10803KT741831PINA  I15V, E35D, M36I, R41K, R57K, D60E, Q61DN, I62IV, L63P, H69Q, V77I, L89M, I93LF
 RenG11662RenG11662KT742690PINA F53LL10V, K14R, Q18E, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, V77I, I93LF
 RenG10579RenG10579KT741607PINA  I15IV, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, I64V, I72T, V77IF
 RenG11051RenG11051KT742079PINAM46MI, I50L, V82VAF53FLL10V, I15V, K20KRT, E34EK, E35D, M36I, R41K, R57RK, D60DE, Q61HN, L63P, I64IL, V77I, I93ILF
 RenG11298RenG11298KT742326PINA  E35D, M36I, R41K, R57K, Q61N, K70KR, V77I, L89MF
 RenG11314RenG11314KT742342PINA  L10V, I13IV, I15IV, E35D, M36I, R41K, Q61N, I62IV, L63AP, H69HY, I72T, V77I, L89MF
 RenG10673RenG10673KT741701PINA  K14KR, D25DV, E35D, M36I, R41K, R57K, Q61N, E65D, I72IT, V77I, L89MF
 RenG10140RenG10140KT741168PINAL90LML33F, F53L, N88TI13V, I15V, K20T, E35D, M36I, N37NT, R41K, K55R, R57K, Q61N, A71V, V77I, L89TF
 RenG10656RenG10656KT741684PINAD30N, M46LL23I, F53L, Q58E, N88DL10I, T12I, I13V, I15V, G16E, K20T, E35D, M36V, P39S, R41K, R57K, Q61N, I62V, A71T, I72R, V77I, L89TF
 RenG10500RenG10500KT741528PINAM46L, G48EQ, L90MF53LL10V, I13IV, K14R, G17D, K20T, E35D, M36I, N37D, R41K, R57K, D60DE, Q61N, I64V, E65D, A71V, I72IV, T74TS, V77I, L89M, I93LF
 RenG10705RenG10705KT741733PINA  G16E, E35D, M36MI, P39Q, R41K, R57K, D60E, Q61N, V77I, L89MF
 RenG11633RenG11633KT742661PINAM46L, N88SQ58EL10V, I13V, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, V77I, L89MF
 RenG11190RenG11190KT742218PINAM46I, I50V, I54V, V82F L10V, I13V, I15V, K20T, E35ED, M36I, N37NK, R41K, R57K, Q61HN, L63DGNS, E65D, I72T, T74A, V77I, L89LMF
 RenG11596RenG11596KT742624PINAI50LF53LT12K, I15V, G17E, K20T, E35D, M36I, N37NT, K45Q, K55T, R57K, Q61N, L63P, A71V, I72T, V77I, L89MF
 RenG11333RenG11333KT742361PINA  G16GE, E35D, M36I, R41K, R57K, D60E, Q61N, I64IV, E65ED, I72IT, V77I, L89LMF
 RenG11543RenG11543KT742571PINA  K14KR, E35D, M36I, R41K, R57K, Q61N, E65D, V77I, L89MF
 RenG10936RenG10936KT741964PINA  L10LI, I15V, L19LI, E35D, M36IT, R41K, R57K, Q61D, I72R, V77I, I93LF
 RenG10218RenG10218KT741246PINA  E35D, M36I, R41K, R57K, Q61N, V77I, L89MF
 RenG10165RenG10165KT741193PINA  L10V, E35D, M36I, R41K, R57K, Q61N, V77I, L89MF
 RenG11343RenG11343KT742371PINAI50LQ58QE, G73ST12K, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, L63P, I64V, V75VI, V77I, V82I, I93LF
 RenG11770RenG11770KT742798PINAM46I, V82F, L90ML33F, K43T, N88GL10IV, I13V, I15V, K20T, E35N, M36I, R57K, Q61D, L63P, A71L, I72T, V77I, L89I, I93LF
 RenG11089RenG11089KT742117PINA  I13V, E35D, M36I, R41K, K45R, R57K, D60E, Q61D, L63P, V77I, L89MF
 RenG10834RenG10834KT741862PINA  L10V, G16E, E35D, M36I, R41K, R57K, Q61N, V77I, L89M, I93LF
 RenG11372RenG11372KT742400PINA L23IL10I, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, A71T, I72T, V77I, L89T, I93LF
 RenG10740RenG10740KT741768PINA  E35D, M36I, R41K, R57K, Q61N, I64IMV, I72T, V77I, V82IF
 RenG11703RenG11703KT742731PINAM46L, I54V, V82F, L90MF53LL10V, K20R, E35D, M36V, N37NT, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64IV, A71AITV, I72IV, V77I, I85IV, L89IM, I93LF
 RenG10504RenG10504KT741532PINAN88S L10LV, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, E65D, V77I, L89M, Q92KF
 RenG10719RenG10719KT741747PINA  L10V, K14KR, I15V, G16E, E35D, M36I, N37ND, R41K, R57K, D60E, Q61N, V77I, L89M, I93LF