<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation V77I
Rx >= 1 PI
IncludeMixtures No
References 12
Patients 83
Isolates 83
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Brindeiro (2002)TVSP24TVSP24AY145818RTV, NFV, Unknown>2  G17S, Q18L, N37E, R57K, L63P, V77I, I93LF
de Sa Filho (2003)BREPM022BREPM022AY182789IDV D30N, I84V L10I, G16E, P39S, K43R, R57K, Q61N, I64V, V77I, G86R, L89M, I93LF
Dumans (2004)RG046RG046AY390209RTV, NFV189M46ML, I54V, L90M L10V, I15IV, K20R, E35D, M36V, N37E, R57K, D60E, Q61DN, I62V, L63LP, A71V, I72T, V77I, I93LF
 223223AY390043NFV13  G16E, E35D, R41K, K70R, V77IF
 242242AY390086NFV177D30N, M46IN88DL10V, I13V, R41K, R57K, D60E, Q61D, I64V, V77I, I85VF
 245245AY390088NFV173  I15V, E35D, M36I, N37A, R41K, K45Q, R57K, D60E, Q61N, V77IF
Gomez-Carrillo (2004)9488394883AY365506PINA G73ST12TP, I13V, I15V, E35D, M36I, R41K, K43KN, R57KN, Q61N, L63P, V77I, I93LF
 9764497644AY365553PINAV32I, M46I, I47V, V82AL24I, L89VL10I, T12N, I15V, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, A71T, V77I, I93LF
 9821698216AY365570PINAL90M I13IV, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, V77I, I93LF
 9883998839AY365584PINA  I15V, E35D, M36I, R41K, Q61N, V77IF
 102998102998AY365663PINAG48V, I54V, V82S L10V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, H69HY, A71V, V77I, I93LF
 103278103278AY365675PINA  I15V, E35D, M36I, N37D, R41K, R57K, Q61N, V77I, I93LF
 106958106958AY365758PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, I93LF
 108506108506AY365789PINA  L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, I72E, V77I, I93LF
 108517108517AY365790PINA  L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, I72E, V77I, I93LF
 109089109089AY365804PINAI54V, V82A, L90MK43T, F53LL10I, L19I, K20R, E35D, M36I, R41K, Q61N, L63T, E65D, C67E, A71V, I72T, T74S, V77I, I93IMF
 109988109988AY365828PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63S, I72T, V77I, I93LF
 114305114305AY365896PINAD30NQ58E, N88DL10I, I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, I72V, V77I, I93LF
 117084117084AY365936PINA  E35D, M36I, R41K, R57K, Q61N, V77I, I93ILF
Thomson (2004)99UFRJ_199UFRJ_1AY455778NFV39  E35D, M36I, R41K, R57K, D60E, Q61D, V77I, L89MF
Rodrigues (2005)BLF_Pat3BR02SP249AY643146Unknown, NFV>74N88S K20T, E35D, M36I, R41K, R57K, Q61N, V77I, L89MF
 BLF_Pat30BR03SP179AY643165IDV, RTV, Unknown, APV, LPV, NFV>152  L10V, I13IV, E35D, M36I, R41K, R57K, D60E, Q61N, I72IT, V77I, L89MF
 BLF_Pat40BR02SP226AY643142NFV148N88S L10I, I13V, I15IV, K20T, E35D, M36I, R41K, R57K, Q61N, E65D, V77I, L89MF
 BLF_Pat42BR02SP154AY643138RTV, Unknown, NFV>70L90M T12R, I15V, L19S, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, T74S, V77I, L89M, I93ILF
Baxter (2006)48-10741074-30626DQ877334PINAV32I, M46I, I47V, I54V, V82A, L90LML24I, L33F, T74PSL10I, I13IV, I15IV, G16E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63S, E65D, A71AV, V77I, L89M, Q92QK, I93LF
 48-10731073-30626DQ877335PINAI54A, V82F L10I, I13IV, L19V, K20R, E35D, M36I, N37H, R41K, K45T, F53C, K55T, Q61D, I62IV, L63T, I64M, A71V, I72T, V77I, I93LF
 48-11101110-30701DQ877398PINAM46I, I54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71V, I72T, V77I, I93LF
 48-32663266-30729DQ878171PINAM46I, I54V, V82AV11VI, L24I, L33F, L89VL10I, I15V, K20A, E35DN, M36L, N37Q, R41K, K55R, R57RK, D60E, Q61E, I62V, L63P, I64L, A71V, I72M, V77I, T91S, I93LF
 48-91519151-30826DQ877716PINAM46FL, I54V, V82A, L90M L10I, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, D60E, Q61N, L63P, H69Y, A71V, I72T, V77I, L89M, I93LF
Santos (2006)128128PR_RTAY275769Unknown, RTV, SQV, IDV>205  I15V, R57K, Q61N, L63P, C67S, I72T, V77IF
Dumans (2009)108PR108PRFJ405037NFV, Unknown>26D30NN88DI15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, A71V, V77I, I93LF
 RENA101RENA101FJ405038NFV78 N88DV11VF, I15V, K20T, E35D, M36I, R41K, R57K, Q61D, I72V, V77I, L89MF
 RENA389RENA389FJ405040NFV30  E35D, M36I, R41K, K45R, R57K, Q61N, L63P, V77I, L89M, I93LF
 RES327_03RES327_03FJ405050RTV, NFV100  I13V, E35D, M36I, R41K, R57K, D60E, Q61E, L63P, V77I, L89MF
 RENA654RENA654FJ405122RTV, NFV, LPV356M46L, I54V, V82A, L90M L10V, I15V, K20R, E35D, M36V, N37E, R57K, D60E, Q61D, I62V, A71V, I72T, V77I, I93LF
 RENA162RENA162FJ405125SQV, NFV, IDV260  L10I, E35D, M36I, R41K, D60E, Q61N, I62V, L63T, C67D, T74S, V77I, L89MF
Sanabani (2009)57906BR579FJ771009PINA  L10P, G16E, E35D, M36I, R41K, D60E, Q61N, I62V, V77I, L89MF
Aulicino (2011)ARM640RCAARM640RCAFJ525835PINAD30NN88DL10V, T12I, I15V, G16E, E35D, M36V, N37E, R41K, K45R, R57K, Q61N, L63T, I72T, V77I, I93LF
 ARN204SBDARN204SBDFJ525854PINAM46MI, I47IV, I54V, V82F, L90MQ58EL10IV, I15V, G17D, K20T, E35N, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, I72R, V77I, I93LF
 ARN311BMSARN311BMSFJ525857PINAM46L, G48Q, I54V, L76V, V82A, L90MV32L, F53L, Q58EL10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, A71V, T74S, V77I, I93LF
 3343-N414ML3343-N414MLHQ158158PINAD30NN88DL10I, I15V, K20T, E35N, M36I, R41K, R57K, D60E, Q61D, L63P, V77I, I93LF
 3225-O153AGL3225-O153AGLHQ158161PINAD30N, L90MN88DT12A, K14R, K20T, E35D, M36I, N37D, R41N, R57K, Q61N, L63P, T74S, V77I, I93LF
 2057-L631ADS2057-L631ADSHQ158272PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, I93LF
Jones (2012)137091137091JN669559PINAI54V, V82VA, L90M L10I, K20KR, E35D, M36I, R41K, Q61N, L63T, A71V, I72T, V77I, I93LF
 140218140218JN669583PINAG48V, I54V, V82SK43TL10V, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63P, H69Y, A71V, V77I, I93LF
 143095143095JN669636PINAM46L, I54V, V82AL33FL10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, V77I, T91S, I93LF
 156156156156JN669852PINA  I15V, E35D, M36I, R41K, R57K, Q61D, I62IV, V77I, I93LF
 157769157769JN669899PINA  T12V, I15V, E35D, M36MI, N37D, R41K, R57K, Q61N, V77I, I93LF
 159810159810JN669966PINAI54S, V82A, L90ML33F, K43TL10I, I13V, I15V, G16E, L19I, K20R, E34R, E35D, M36I, N37T, R41K, R57K, Q61D, A71IL, I72R, V77I, I93LF
 160102160102JN669969PINA  I15V, K20KR, M36MI, R41K, R57K, Q61N, A71T, I72EV, V77I, I93LF
 161429161429JN670008PINA  I15V, E35D, M36I, R41K, R57K, Q61N, V77IF
 162645162645JN670045PINAI54V, V82A, I84V, L90ML23I, Q58EL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63C, I64V, A71V, V77I, I93LF
 163933163933JN670073PINAM46I, I47V, I54V, V82F, L90ML89VL10I, I15V, G17D, K20T, E35N, M36I, R41K, K55KR, R57K, Q61N, I62V, L63P, T74S, V77I, I85V, I93LF
 164954164954JN670089PINA  I15V, E35D, M36I, R41K, R57K, Q61N, I72V, V77I, I93LF
 165724165724JN670114PINAD30NN88DI15IV, K20T, E35N, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, I64L, A71AV, V77I, I93LF
 167151167151JN670145PINAI54L, L90M L10V, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63C, E65D, I72T, V77I, I93LF
 168544168544JN670182PINAM46L, V82A T12TP, L19LQ, E35D, M36I, R41K, R57K, Q61D, L63P, V77I, I93LF
 170484170484JN670222PINA  E35D, M36I, N37D, R41RK, Q61N, V77IF
 177362177362JN670438PINA  T12I, I15V, E35D, M36I, N37D, R57K, Q61S, I62V, A71T, V77I, I93LF
 178225178225JN670477PINAD30N I15V, K20T, E35D, M36I, N37NT, R41K, R57K, Q61N, L63LP, V77I, I93LF
 179184179184JN670503PINAI54IV, V82VF, L90LML89LVR8R*, L10LI, I15V, K20KT, E35DN, M36I, N37D, R41K, R57K, Q61DN, L63LP, I64IV, T74TS, V77I, I85IV, I93LF
 179613179613JN670518PINAI54V, V82A, L90MF53LL10I, I15V, G16E, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63T, E65D, I72T, V77IF
 179672179672JN670523PINAD30N, L90LMN88DL10I, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, L63P, E65ED, K70R, V77I, I93LF
 180532180532JN670549PINA  T4TA, I15V, E35D, M36I, N37NY, R41K, V56VI, R57K, Q61N, L63G, H69Q, V77IF
 180609180609JN670551PINA  I15V, R41K, R57K, Q61N, A71T, I72E, V77I, I93LF
 181927181927JN670593PINA  E35D, M36I, R41K, R57K, D60E, Q61D, I62V, V77I, I93LF
 183117183117JN670638PINA  L10V, I15V, E35D, M36I, R41K, R57RK, Q61D, V77I, I93LF
 184561184561JN670682PINA  I13V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, I93LF
 184986184986JN670691PINA  T12P, K14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, I64V, H69Y, V77I, I93LF
 187706187706JN670737PINA  I15V, Q18E, E35D, M36I, R41K, R57K, Q61N, L63T, V77I, I93LF
 187820187820JN670742PINAI50IL, V82VA, N88NSL10LFII15IV, K20T, E35DN, M36I, N37ND, R41K, R57K, Q61N, L63P, A71AITV, T74S, V77I, L89LMF
 192094192094JN670846PINAI54L, N88S L10V, T12R, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, T74S, V77I, I93LF
 192895192895JN670872PINA  I15V, E35D, M36I, R41K, R57K, Q61D, I72KR, V77IF
 192902192902JN670873PINA  L10LI, K14R, I15V, L19I, E35D, M36I, N37D, R41K, R57K, D60DE, Q61DN, I62IV, L63AP, I64IL, V77I, I93LF
 195201195201JN670970PINAD30N, I54VI47ML10I, K20T, E35N, M36I, N37D, K45A, V56A, R57K, Q61N, I62V, L63P, V77I, V82I, N88E, L89MF
 195702195702JN670997PINA  I3N, L10LI, I15IV, G16E, K20KM, E35D, M36MI, R41K, R57K, Q61N, L63G, V77I, I93LF
 196945196945JN671045PINA  L10V, I15V, E35D, M36I, R41K, R57K, Q61N, I72T, V77IF
 197833197833JN671086PINAL90M L10V, I13V, I15V, K20T, E35DN, M36I, P39Q, R57K, D60E, Q61D, L63P, A71AV, V77I, I93LF
 198179198179JN671108PINA  Q2QH, I3HLQ, L5LHQ, W6WCRS, R8RQ, T12S, I15V, K20KR, R41K, R57K, Q61N, V77I, I93LF
 198466198466JN671120PINAL90M I15V, K20T, E35G, M36I, R41K, R57K, Q61N, I62V, L63P, I72IV, T74S, V77I, I93LF
 199190199190JN671152PINA  T12A, E35D, M36I, R41K, R57K, Q61N, L63P, V77I, I93LF
 199882199882JN671185PINAM46L, I54V, V82AL24I, Q58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, V77IF
 202696202696JN671286PINA  L10I, T12P, E35D, M36I, N37D, R41K, R57K, D60E, Q61D, L63S, E65D, A71T, I72IT, V77I, I93LF