<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L76V
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 33
Isolates 33
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)105436105436AY365727PINAM46L, I54V, L76V, V82AL23LIL10I, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63C, L89MF
 119804119804AY365974PINAM46L, G48V, I54V, L76V, V82A, L90ML33F, K43TL10I, I15V, G16E, K20M, E35H, M36L, R41K, K55R, R57K, Q61N, L63S, E65D, A71V, T74S, I93LF
 126798126798AY366058PINAM46L, I54V, L76V, V82A L10V, I15V, K20R, E35D, M36I, N37D, K55R, R57K, D60E, Q61D, L63P, A71VF
Baxter (2006)48-11101110-30701DQ877398PINAM46I, I54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71V, I72T, V77I, I93LF
 48-11031103-30708DQ877410PINAM46L, I54V, L76V, V82A, L90ML33F, K43TL10I, I13V, I15V, G16E, K20M, E35H, M36L, R41K_K, K55R, R57K, Q61N, L63S, E65D, A71V, T74S, L89LM, I93LF
 48-30433043-30305DQ877955PINAM46I, G48M, I54V, L76V, V82A, L90MK43T, F53LT4S, L10V, K14Q, I15V, G16E, L19I, K20R, E35D, M36V, P39S, K55R, R57K, Q61N, I62V, L63T, E65H, H69R, I72V, T74S, L89M, C95CSF
 48-92669266-30915DQ877516PINAM46L, I54V, L76V, V82A, L90M L10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, H69R, K70R, A71V, I72IV, L89M, I93LF
Cardoso (2009)3131BRGO3131FJ638460PINAM46L, I54V, L76V, V82M, L90M L10V, I15V, K20R, E35D, M36V, N37E, R41K, K55R, R57K, Q61N, L63P, A71V, T74TS, I93LF
Dumans (2009)RENA395RENA395FJ405051IDV, RTV200L76VL89VK20I, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, I93LF
 RENA244RENA244FJ405174RTV, SQV, IDV, NFV, Unknown>195M46I, I50V, L76V, V82A, L90M L10V, I15V, K20R, E34A, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, A71V, I93MF
Aulicino (2011)ARL119CLARL119CLFJ525805PINAM46I, I54V, L76V, V82AF53FLL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, A71V, I72V, I93LF
 ARL589CJAARL589CJAFJ525811PINAM46L, I54V, L76V, V82F, L90ML33F, G73A, L89VL10V, I13V, K14R, I15V, G17E, K20T, E35N, M36I, R57K, Q61D, L63P, A71V, I93LF
 ARM896DNGARM896DNGFJ525845PINAM46I, I54L, L76V, V82AL24I, K43TL10I, T12P, I15V, G16E, L19P, K20R, E35D, M36I, N37D, K55R, R57K, Q61D, A71V, I72R, I93LF
 ARN311BMSARN311BMSFJ525857PINAM46L, G48Q, I54V, L76V, V82A, L90MV32L, F53L, Q58EL10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, A71V, T74S, V77I, I93LF
 4460-L6744460-L674HQ158242PINAM46I, I54V, L76V, V82AL24I, K43TL10I, T12P, I15V, G16E, L19P, K20R, E35D, M36I, N37D, K55R, R57K, D60E, Q61D, A71V, I72R, I93LF
Jones (2012)156594156594JN669867PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K14R, Q18E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63T, E65D, A71V, L89M, I93LF
 157416157416JN669883PINAM46I, I50V, I54V, L76V, V82A, L90LMQ58E, L89VL10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, A71V, G73DE, I85V, Q92K, I93LF
 157709157709JN669896PINAM46I, I54V, L76V, V82AL33F, K43KTL10I, I15IV, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63T, H69Y, I72T, L89M, I93LF
 160560160560JN669981PINAM46I, I54V, L76V, L90ML89VL10V, I13V, I15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 165364165364JN670097PINAM46I, I54V, L76V, V82A L10V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, T74SF
 171337171337JN670256PINAM46I, I54V, L76V, V82A L10V, I15V, K20R, M36I, R41K, R57K, Q61N, L63T, E65D, I72T, L89M, I93LF
 172770172770JN670299PINAM46L, I54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63P, C67Q, A71V, I72T, I93LF
 172778172778JN670302PINAI54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, A71V, I72T, I85V, I93LF
 175786175786JN670373PINAM46L, I54V, L76V, V82A L10IV, T12E, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, H69Y, A71V, I72T, L89LM, I93LF
 176698176698JN670410PINAM46I, I54V, L76V, V82F L10I, T12I, I13V, I15V, K20I, E35N, M36I, N37D, R41K, R57K, Q61N, L63P, I64VF
 181091181091JN670565PINAM46I, I47V, I54V, L76V, V82AQ58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I72T, I93LF
 181761181761JN670585PINAM46I, I50V, I54V, L76V, V82T I3F, L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63T, C67W, A71V, I72T, I93LF
 183349183349JN670642PINAM46L, I54V, L76V, V82A L10I, T12I, I15V, G16E, L19I, K20M, E35DN, M36I, R41RK, R57K, Q61N, L63LH, I85V, L89IF
 186090186090JN670712PINAM46I, I54V, L76V, V82A L10V, T12Q, I15V, L19Q, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63PF
 189227189227JN670768PINAM46I, I47V, I54V, L76V, V82A L10V, T12TK, I15V, G16E, L19I, K20R, E35D, M36I, R41K, K45R, K55KR, R57K, Q61N, L63T, A71V, I72T, I93LF
 190428190428JN670798PINAM46L, I54V, L76V, V82A, L90MQ58EL10V, I15V, G16A, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P, A71V, I72V, I93LF
 192047192047JN670844PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, G16E, K20R, E35D, M36I, R41RK, K55R, R57K, D60E, Q61N, I62IV, L63C, E65ED, L89MF
 194888194888JN670955PINAM46I, I47IV, I54V, L76V, V82AK43T, Q58QEL10IV, I15V, Q18E, L19LI, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61N, I62V, L63P, A71AV, L89M, I93ILF