<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L76V
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 82
Isolates 82
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)105436105436AY365727PINAM46L, I54V, L76V, V82AL23LIL10I, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63C, L89MF
Baxter (2006)12-10691069-30528DQ876395PINAM46I, I54V, L76V, V82AK43TL10IV, T12I, I15V, K20R, E35D, M36I, R41K, K55R, D60DE, Q61N, I62IV, L63T, E65D, H69HR, I72T, T74S, L89MF
 48-11621162-30814DQ877267PINAM46L, I54V, L76V, V82AL23IL10I, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63C, L89MF
 48-30433043-30305DQ877955PINAM46I, G48M, I54V, L76V, V82A, L90MK43T, F53LT4S, L10V, K14Q, I15V, G16E, L19I, K20R, E35D, M36V, P39S, K55R, R57K, Q61N, I62V, L63T, E65H, H69R, I72V, T74S, L89M, C95CSF
 48-92669266-30915DQ877516PINAM46L, I54V, L76V, V82A, L90M L10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, H69R, K70R, A71V, I72IV, L89M, I93LF
Waleria-Aleixo (2008)08PR05037408PR050374FJ591399PINAM46I, L76V, I84V L10I, K20R, E35D, M36I, R57K, Q61D, L63P, H69C, A71V, I72R, L89M, I93LF
 08RJ06061808RJ060618FJ591778PINAM46I, I50V, L76V, V82AL24I, L33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, K55KR, R57K, Q61N, L63T, C67E, L89MF
 08PR05023608PR050236FJ591265PINAI54V, L76V, I84V, L90M L10I, I15V, G16GA, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, L63LP, A71V, P79S, V82I, L89I, Q92K, I93LF
Cardoso (2009)3144BRGO3144FJ638464PINAM46I, I50V, I54V, L76V, V82AL89VL10I, I13V, G16E, K20R, M36I, N37ND, R41RK, K55R, D60E, Q61N, A71V, I72RF
Dumans (2009)RENA395RENA395FJ405051IDV, RTV200L76VL89VK20I, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, I93LF
 RENA244RENA244FJ405174RTV, SQV, IDV, NFV, Unknown>195M46I, I50V, L76V, V82A, L90M L10V, I15V, K20R, E34A, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, A71V, I93MF
Aulicino (2011)ARL119CLARL119CLFJ525805PINAM46I, I54V, L76V, V82AF53FLL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, A71V, I72V, I93LF
Charpentier (2011)CR-51CR-51FJ688257PINAM46I, I54V, L76V, V82AL24I, L33F, Q58EL10I, I13V, K14R, I15IV, G16E, K20R, E35D, M36I, P39Q, R41K, K55R, I62V, L63ST, H69K, L89MF
Jones (2012)156594156594JN669867PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K14R, Q18E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63T, E65D, A71V, L89M, I93LF
 160560160560JN669981PINAM46I, I54V, L76V, L90ML89VL10V, I13V, I15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 182090182090JN670599PINAM46I, I54V, L76VL89VK20P, E35N, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 183349183349JN670642PINAM46L, I54V, L76V, V82A L10I, T12I, I15V, G16E, L19I, K20M, E35DN, M36I, R41RK, R57K, Q61N, L63LH, I85V, L89IF
 189227189227JN670768PINAM46I, I47V, I54V, L76V, V82A L10V, T12TK, I15V, G16E, L19I, K20R, E35D, M36I, R41K, K45R, K55KR, R57K, Q61N, L63T, A71V, I72T, I93LF
 194888194888JN670955PINAM46I, I47IV, I54V, L76V, V82AK43T, Q58QEL10IV, I15V, Q18E, L19LI, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61N, I62V, L63P, A71AV, L89M, I93ILF
Diaz (2015)RenG15620RenG15620KT746648PINAM46I, I54V, L76V, V82A, L90M L10I, I13V, I15IV, G16E, K20I, E35N, M36I, N37NS, R41RK, K55R, R57K, Q61N, L63H, A71T, I72V, L89I, T91SF
 RenG16848RenG16848KT747876PINAM46I, I54V, L76V, V82AL33F, K43T, N83DL10V, I13V, L19V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, I62V, I72R, T74S, L89MF
 RenG15889RenG15889KT746917PINAM46I, I54V, L76V, V82AL10F, L24I, L33FI13V, K20R, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, I72V, L89IF
 RenG15589RenG15589KT746617PINAM46I, I54V, L76V, V82F L10I, K20KR, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, I72V, P79PL, I85IV, L89MF
 RenG16477RenG16477KT747505PINAM46I, I54V, L76V, V82A L10I, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, L89IF
 RenG16248RenG16248KT747276PINAM46L, I54V, L76V, V82A, L90ML23IL10I, I13V, I15V, K20I, E35N, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I64L, A71V, I72V, T74S, I93LF
 RenG17232RenG17232KT748260PINAM46I, I47V, I50V, L76V, V82AV11I, L33F, F53LL10V, I13V, I15V, Q18L, L19Q, K20R, E34KNRS, E35D, M36I, N37D, R41K, R57K, Q61N, I66F, A71V, L89I, T91AF
 RenG15968RenG15968KT746996PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG16257RenG16257KT747285PINAM46I, I54V, L76V, V82AL24IL10I, I13V, K20M, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63P, A71T, I72T, T74S, L89IF
 RenG15729RenG15729KT746757PINAM46L, I54V, L76V, V82AL33FL5LF, W6L, L10V, I13V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, G68D, L89IF
 RenG15949RenG15949KT746977PINAG48A, I54V, L76V, V82A, L90MF53LL10I, I15V, G16GA, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63T, A71V, I72T, T74S, L89M, I93LF
 RenG16204RenG16204KT747232PINAM46I, I54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63A, T74S, L89MF
 RenG15768RenG15768KT746796PINAM46I, I54V, L76V, V82AL24I, Q58EL10I, T12N, I15V, L19I, K20R, E34G, E35D, M36I, N37D, R41K, R57K, Q61DN, L63T, E65D, I72T, L89MF
 RenG16968RenG16968KT747996PINAM46L, I54V, L76V, V82A, L90M R8Q, L10I, I15AV, K20R, E35D, M36I, N37G, R41K, R57K, Q61N, L63T, A71V, I72T, L89M, I93LF
 RenG15721RenG15721KT746749PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, L19V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, H69Y, I72T, L89M, I93LF
 RenG16881RenG16881KT747909PINAV32I, M46I, I54V, L76V, V82M, I84VQ58EL10I, I15V, G16GE, K20KR, E35E_D, M36I, N37E, K55KR, R57RK, I62V, L63A, E65ED, A71V, I72V, P79AF
 RenG17344RenG17344KT748372PINAM46I, I54V, L76V, V82A, L90ML33FL10V, T12I, I13V, G16E, K20R, E35D, M36I, N37T, R41K, R57K, D60E, Q61D, I62V, I72R, L89IF
 RenG14016RenG14016KT745044PINAM46I, I54V, L76V, V82A L10I, T12TN, I15V, L19I, K20R, E35D, M36I, R57K, Q61N, L63T, E65D, A71V, I72T, L89M, Q92K, I93LF
 RenG13971RenG13971KT744999PINAM46I, I47IV, I54IV, L76V, I84V L10I, I15IV, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, A71V, I72R, L89M, I93LF
 RenG15448RenG15448KT746476PINAM46MIL, I54V, L76V, V82AL33LF, K43TL10V, T12K, I15V, L19I, K20R, E35D, M36I, N37E, R41K, I62V, L63C, T74S, L89IF
 RenG13805RenG13805KT744833PINAM46I, I47IV, L76VL10F, L33I, N83ND, L89VI13V, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63LP, I93ILF
 RenG13921RenG13921KT744949PINAM46I, G48M, I54V, L76V, V82A, I84VL33F, N83DL10IV, I13V, K20R, E35ED, M36I, N37EK, R41P, R57K, Y59YF, Q61N, L63P, L89IM, I93N, T96XF
 RenG14157RenG14157KT745185PINAM46L, G48T, I54V, L76V, V82AF53LI15V, G16E, L19I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, E65D, A71V, I72T, I93LF
 RenG15158RenG15158KT746186PINAM46I, I54V, L76V, V82T, I84VK43TL10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, D60DE, Q61N, L63P, I64L, A71V, I72VF
 RenG14385RenG14385KT745413PINAM46L, G48Q, I54V, L76V, I84VL24IL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57RK, Q61N, L63T, I64L, I72T, V82VI, L89M, Q92QKF
 RenG14293RenG14293KT745321PINAM46L, I54V, L76V, V82AL33FL10V, I13V, G16E, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63V, E65D, I72T, T74A, L89MF
 RenG14011RenG14011KT745039PINAI54L, L76V, V82FL33F, Q58EL10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, P39T, R41K, R57K, Q61N, A71V, I72R, V77I, L89IM, I93LF
 RenG13850RenG13850KT744878PINAM46I, I54V, L76V, V82SL24I, L33F, Q58EL10I, I13V, L19I, K20M, E35N, M36I, N37E, K55R, R57K, D60E, Q61N, L63P, C67Q, K70R, I72V, L89MF
 RenG14484RenG14484KT745512PINAM46I, I54V, L76V, V82AK43TL10I, G16GA, L19IV, K20R, E35D, M36I, N37E, R57K, Q61N, I62V, L63P, E65ED, L89MF
 RenG13884RenG13884KT744912PINAM46I, I54V, L76V, V82AL10FIK14KR, G17D, L19I, K20R, E35D, M36I, N37NDEK, R41RK, R57K, Q61N, L63T, E65D, I72T, L89MF
 RenG13781RenG13781KT744809PINAM46I, I50V, I54V, L76V L10I, I15V, K20T, E35N, M36I, R41K, R57K, Q61D, I62V, L63V, I64IV, A71V, T74A, V82I, L89M, I93LF
 RenG15021RenG15021KT746049PINAM46L, I54LV, L76V, V82AL33FL10V, I13IV, G16E, L19V, K20R, E35D, M36I, N37DE, P39PQ, K55R, R57K, Q61N, L63T, E65D, I72V, T74S, L89MF
 RenG15072RenG15072KT746100PINAM46L, I54V, L76V, V82A, L90ML33F, Q58EL10V, I13V, K14R, G16E, K20R, E35D, M36I, N37E, P39S, R41RK, K55R, R57K, D60DE, Q61N, I62V, L63T, I64V, K70KT, V77IF
 RenG13661RenG13661KT744689PINAM46I, I54V, L76V, V82A W6WG, L10I, I15V, L19I, K20R, E35D, M36I, N37E, R41K, K55KR, R57K, Q61N, I62V, L63AT, E65D, L89MF
 RenG14993RenG14993KT746021PINAM46I, I54V, L76V, V82AQ58EL10LR, T12A, K14R, I15V, G16E, E35N, M36IV, N37D, R41K, K55R, R57K, D60E, Q61D, L63T, I72T, L89MF
 RenG12947RenG12947KT743975PINAM46I, I54V, L76V, V82AV11VI, L33I, N83DL10V, I13A, K14KR, A22V, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63P, L89IF
 RenG12344RenG12344KT743372PINAM46I, I54V, L76V, V82FL33LF, Q58EL10V, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61D, I62V, L63LP, H69Y, A71AV, I72T, L89M, I93LF
 RenG12039RenG12039KT743067PINAM46I, I54V, L76V, V82F L10I, K20KR, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, I72V, P79PL, I85IV, L89MF
 RenG13470RenG13470KT744498PINAM46I, I54V, L76V, V82A L10IV, I13IV, I15V, G16E, K20T, E35D, M36I, P39T, R41K, R57K, Q61N, L63T, E65D, I72V, T74S, V77I, L89MF
 RenG11951RenG11951KT742979PINAM46I, I54V, L76V, V82FL33LF, Q58EL10V, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61D, I62V, L63LP, H69Y, A71AV, I72T, L89M, I93LF
 RenG12901RenG12901KT743929PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG13251RenG13251KT744279PINAM46I, L76V, V82A I15V, K20T, E34K, E35D, M36V, P39S, R41K, R57K, D60E, Q61N, I62V, L63P, T74S, L89MF
 RenG13395RenG13395KT744423PINAM46I, I54V, L76V, L90MQ58QET12K, I15V, G16E, K20T, E35D, M36I, N37E, R57K, D60E, Q61N, L63S, H69HR, L89IF
 RenG12888RenG12888KT743916PINAM46L, I54V, L76V, V82A, L90ML10F, Q58EI15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, I62V, L63P, A71V, L89I, I93LF
 RenG11967RenG11967KT742995PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG12524RenG12524KT743552PINAG48A, I54V, L76V, V82A, I84VV11VI, L24I, L33F, K43T, M46V, F53L, N83DL10Y, L19I, K20R, E35N, M36I, N37D, K55R, R57K, D60E, Q61N, I62V, L63P, H69Y, A71V, I72K, L89I, T91A, Q92KF
 RenG12087RenG12087KT743115PINAM46L, I54V, L76V, V82MQ58EL10I, I13V, I15V, K20T, E35DN, M36I, R41K, R57K, Q61N, I62V, E65D, T74S, L89MF
 RenG12193RenG12193KT743221PINAM46I, I54V, L76V, V82A, L90M L10I, I15V, L19I, K20R, E34N, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, I72V, T74SF
 RenG12980RenG12980KT744008PINAM46IL, G48Q, I54V, L76V, V82A, L90MF53LL10V, G16A, L19LI, K20R, E35D, M36I, R41K, K55R, R57K, I62V, L63P, A71V, I72V, I93LF
 RenG12368RenG12368KT743396PINAM46I, I54V, L76VG73SL10V, I15V, L19V, E35D, M36I, R41K, R57K, D60E, I62L, A71IV, V77I, I85V, L89T, Q92KF
 RenG13089RenG13089KT744117PINAM46I, I54V, L76V, V82L L10I, T12N, I15V, L19I, K20T, D25DN, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71I, V77I, I85V, L89T, Q92KF
 RenG12539RenG12539KT743567PINAM46I, I54V, L76V, I84VN83DR8X, L10I, T12I, I13A, G16E, K20R, A22V, E35D, M36I, R41K, R57K, Q61N, I72R, L89IF
 RenG11950RenG11950KT742978PINAM46I, I54V, L76VQ58ET12K, K14M, I15V, G16E, K20T, E35D, M36I, N37E, R57K, Q61N, L63R, E65D, L89MF
 RenG12499RenG12499KT743527PINAM46I, I54V, L76V, V82AL33FL10I, T12I, I13V, I15V, G16E, K20*, D29V, E35D, M36I, N37DE, R41K, K55R, R57K, Q61N, I62R, L63V, E65ED, L89MF
 RenG10514RenG10514KT741542PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, K20R, E35D, M36I, N37K, R41K, K55R, R57K, Q61N, I62IV, L63P, I72V, P79A, L89FF
 RenG11279RenG11279KT742307PINAG48V, I54V, L76V, V82A, I84VM46V, Q58EL10I, I15V, G16E, K20R, E35D, M36I, K55R, R57K, Q61N, L63C, L89IF
 RenG10265RenG10265KT741293PINAM46I, I54V, L76V, V82AL24IL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, I64IL, A71V, I72T, L89I, I93LF
 RenG10556RenG10556KT741584PINAM46I, I54V, L76V, V82AK43TL10I, K14R, I15V, G16GA, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, I62V, L63T, H69HY, I72T, L89M, I93LF
 RenG10050RenG10050KT741078PINAM46I, I54V, L76V, V82AL33FL10V, I13V, K14R, K20KR, E35D, M36I, R41K, R57K, Q61N, L63P, E65D, K70R, L89MF
 RenG11155RenG11155KT742183PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, K20R, E35D, M36I, N37D, K55R, R57K, D60E, Q61N, I62V, L63S, L89MF
 RenG10914RenG10914KT741942PINAM46I, I47V, I54V, L76V, V82TL24I, K43TL10IV, T12TP, I13V, I15V, G16E, K20I, M36I, N37E, I62V, L63N, A71V, L89IF
 RenG10068RenG10068KT741096PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, E35D, M36I, N37D, K55R, R57K, D60E, Q61N, I62V, L63S, L89MF
 RenG11735RenG11735KT742763PINAM46I, I54V, L76V, L90M L10V, I13V, I15V, K20T, E35N, M36I, R41K, R57K, D60E, Q61N, I62IV, L63P, A71I, L89I, T91S, I93LF