<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L76V
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 88
Isolates 88
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)105436105436AY365727PINAM46L, I54V, L76V, V82AL23LIL10I, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63C, L89MF
 119804119804AY365974PINAM46L, G48V, I54V, L76V, V82A, L90ML33F, K43TL10I, I15V, G16E, K20M, E35H, M36L, R41K, K55R, R57K, Q61N, L63S, E65D, A71V, T74S, I93LF
 126798126798AY366058PINAM46L, I54V, L76V, V82A L10V, I15V, K20R, E35D, M36I, N37D, K55R, R57K, D60E, Q61D, L63P, A71VF
Baxter (2006)48-11101110-30701DQ877398PINAM46I, I54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71V, I72T, V77I, I93LF
 48-11031103-30708DQ877410PINAM46L, I54V, L76V, V82A, L90ML33F, K43TL10I, I13V, I15V, G16E, K20M, E35H, M36L, R41K_K, K55R, R57K, Q61N, L63S, E65D, A71V, T74S, L89LM, I93LF
 48-30433043-30305DQ877955PINAM46I, G48M, I54V, L76V, V82A, L90MK43T, F53LT4S, L10V, K14Q, I15V, G16E, L19I, K20R, E35D, M36V, P39S, K55R, R57K, Q61N, I62V, L63T, E65H, H69R, I72V, T74S, L89M, C95CSF
 48-92669266-30915DQ877516PINAM46L, I54V, L76V, V82A, L90M L10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, H69R, K70R, A71V, I72IV, L89M, I93LF
Cardoso (2009)3131BRGO3131FJ638460PINAM46L, I54V, L76V, V82M, L90M L10V, I15V, K20R, E35D, M36V, N37E, R41K, K55R, R57K, Q61N, L63P, A71V, T74TS, I93LF
Dumans (2009)RENA395RENA395FJ405051IDV, RTV200L76VL89VK20I, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, I93LF
 RENA244RENA244FJ405174RTV, SQV, IDV, NFV, Unknown>195M46I, I50V, L76V, V82A, L90M L10V, I15V, K20R, E34A, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, A71V, I93MF
Aulicino (2011)ARL119CLARL119CLFJ525805PINAM46I, I54V, L76V, V82AF53FLL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, A71V, I72V, I93LF
 ARL589CJAARL589CJAFJ525811PINAM46L, I54V, L76V, V82F, L90ML33F, G73A, L89VL10V, I13V, K14R, I15V, G17E, K20T, E35N, M36I, R57K, Q61D, L63P, A71V, I93LF
 ARM896DNGARM896DNGFJ525845PINAM46I, I54L, L76V, V82AL24I, K43TL10I, T12P, I15V, G16E, L19P, K20R, E35D, M36I, N37D, K55R, R57K, Q61D, A71V, I72R, I93LF
 ARN311BMSARN311BMSFJ525857PINAM46L, G48Q, I54V, L76V, V82A, L90MV32L, F53L, Q58EL10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, A71V, T74S, V77I, I93LF
 4460-L6744460-L674HQ158242PINAM46I, I54V, L76V, V82AL24I, K43TL10I, T12P, I15V, G16E, L19P, K20R, E35D, M36I, N37D, K55R, R57K, D60E, Q61D, A71V, I72R, I93LF
Jones (2012)156594156594JN669867PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K14R, Q18E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63T, E65D, A71V, L89M, I93LF
 157416157416JN669883PINAM46I, I50V, I54V, L76V, V82A, L90LMQ58E, L89VL10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, A71V, G73DE, I85V, Q92K, I93LF
 157709157709JN669896PINAM46I, I54V, L76V, V82AL33F, K43KTL10I, I15IV, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63T, H69Y, I72T, L89M, I93LF
 160560160560JN669981PINAM46I, I54V, L76V, L90ML89VL10V, I13V, I15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 165364165364JN670097PINAM46I, I54V, L76V, V82A L10V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, T74SF
 171337171337JN670256PINAM46I, I54V, L76V, V82A L10V, I15V, K20R, M36I, R41K, R57K, Q61N, L63T, E65D, I72T, L89M, I93LF
 172770172770JN670299PINAM46L, I54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63P, C67Q, A71V, I72T, I93LF
 172778172778JN670302PINAI54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, A71V, I72T, I85V, I93LF
 175786175786JN670373PINAM46L, I54V, L76V, V82A L10IV, T12E, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, H69Y, A71V, I72T, L89LM, I93LF
 176698176698JN670410PINAM46I, I54V, L76V, V82F L10I, T12I, I13V, I15V, K20I, E35N, M36I, N37D, R41K, R57K, Q61N, L63P, I64VF
 181091181091JN670565PINAM46I, I47V, I54V, L76V, V82AQ58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I72T, I93LF
 181761181761JN670585PINAM46I, I50V, I54V, L76V, V82T I3F, L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63T, C67W, A71V, I72T, I93LF
 183349183349JN670642PINAM46L, I54V, L76V, V82A L10I, T12I, I15V, G16E, L19I, K20M, E35DN, M36I, R41RK, R57K, Q61N, L63LH, I85V, L89IF
 186090186090JN670712PINAM46I, I54V, L76V, V82A L10V, T12Q, I15V, L19Q, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63PF
 189227189227JN670768PINAM46I, I47V, I54V, L76V, V82A L10V, T12TK, I15V, G16E, L19I, K20R, E35D, M36I, R41K, K45R, K55KR, R57K, Q61N, L63T, A71V, I72T, I93LF
 190428190428JN670798PINAM46L, I54V, L76V, V82A, L90MQ58EL10V, I15V, G16A, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P, A71V, I72V, I93LF
 192047192047JN670844PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, G16E, K20R, E35D, M36I, R41RK, K55R, R57K, D60E, Q61N, I62IV, L63C, E65ED, L89MF
 194888194888JN670955PINAM46I, I47IV, I54V, L76V, V82AK43T, Q58QEL10IV, I15V, Q18E, L19LI, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61N, I62V, L63P, A71AV, L89M, I93ILF
Diaz (2015)RenG15620RenG15620KT746648PINAM46I, I54V, L76V, V82A, L90M L10I, I13V, I15IV, G16E, K20I, E35N, M36I, N37NS, R41RK, K55R, R57K, Q61N, L63H, A71T, I72V, L89I, T91SF
 RenG16848RenG16848KT747876PINAM46I, I54V, L76V, V82AL33F, K43T, N83DL10V, I13V, L19V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, I62V, I72R, T74S, L89MF
 RenG15589RenG15589KT746617PINAM46I, I54V, L76V, V82F L10I, K20KR, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, I72V, P79PL, I85IV, L89MF
 RenG16477RenG16477KT747505PINAM46I, I54V, L76V, V82A L10I, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, L89IF
 RenG16248RenG16248KT747276PINAM46L, I54V, L76V, V82A, L90ML23IL10I, I13V, I15V, K20I, E35N, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I64L, A71V, I72V, T74S, I93LF
 RenG17232RenG17232KT748260PINAM46I, I47V, I50V, L76V, V82AV11I, L33F, F53LL10V, I13V, I15V, Q18L, L19Q, K20R, E34KNRS, E35D, M36I, N37D, R41K, R57K, Q61N, I66F, A71V, L89I, T91AF
 RenG15968RenG15968KT746996PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG15729RenG15729KT746757PINAM46L, I54V, L76V, V82AL33FL5LF, W6L, L10V, I13V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, G68D, L89IF
 RenG15949RenG15949KT746977PINAG48A, I54V, L76V, V82A, L90MF53LL10I, I15V, G16GA, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63T, A71V, I72T, T74S, L89M, I93LF
 RenG16204RenG16204KT747232PINAM46I, I54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63A, T74S, L89MF
 RenG16968RenG16968KT747996PINAM46L, I54V, L76V, V82A, L90M R8Q, L10I, I15AV, K20R, E35D, M36I, N37G, R41K, R57K, Q61N, L63T, A71V, I72T, L89M, I93LF
 RenG15721RenG15721KT746749PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, L19V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, H69Y, I72T, L89M, I93LF
 RenG14016RenG14016KT745044PINAM46I, I54V, L76V, V82A L10I, T12TN, I15V, L19I, K20R, E35D, M36I, R57K, Q61N, L63T, E65D, A71V, I72T, L89M, Q92K, I93LF
 RenG13971RenG13971KT744999PINAM46I, I47IV, I54IV, L76V, I84V L10I, I15IV, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, A71V, I72R, L89M, I93LF
 RenG13805RenG13805KT744833PINAM46I, I47IV, L76VL10F, L33I, N83ND, L89VI13V, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63LP, I93ILF
 RenG14157RenG14157KT745185PINAM46L, G48T, I54V, L76V, V82AF53LI15V, G16E, L19I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, E65D, A71V, I72T, I93LF
 RenG15158RenG15158KT746186PINAM46I, I54V, L76V, V82T, I84VK43TL10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, D60DE, Q61N, L63P, I64L, A71V, I72VF
 RenG13799RenG13799KT744827PINAM46I, I54V, L76V, V82A, L90M L5I, L10V, K14KR, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, A71V, I93LF
 RenG14684RenG14684KT745712PINAM46L, I54V, L76V, V82AL33FL10V, T12I, I13V, I15V, G16E, E35D, M36I, N37D, R57K, Q61N, L63T, E65D, I72T, T91SF
 RenG13558RenG13558KT744586PINAM46I, I54V, L76V, V82AF53FLL10V, I15IV, K20R, E35D, M36I, N37D, K55R, R57K, Q61N, I62IV, L63P, A71V, I72T, I93LF
 RenG14293RenG14293KT745321PINAM46L, I54V, L76V, V82AL33FL10V, I13V, G16E, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63V, E65D, I72T, T74A, L89MF
 RenG14011RenG14011KT745039PINAI54L, L76V, V82FL33F, Q58EL10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, P39T, R41K, R57K, Q61N, A71V, I72R, V77I, L89IM, I93LF
 RenG13850RenG13850KT744878PINAM46I, I54V, L76V, V82SL24I, L33F, Q58EL10I, I13V, L19I, K20M, E35N, M36I, N37E, K55R, R57K, D60E, Q61N, L63P, C67Q, K70R, I72V, L89MF
 RenG13884RenG13884KT744912PINAM46I, I54V, L76V, V82AL10FIK14KR, G17D, L19I, K20R, E35D, M36I, N37NDEK, R41RK, R57K, Q61N, L63T, E65D, I72T, L89MF
 RenG13781RenG13781KT744809PINAM46I, I50V, I54V, L76V L10I, I15V, K20T, E35N, M36I, R41K, R57K, Q61D, I62V, L63V, I64IV, A71V, T74A, V82I, L89M, I93LF
 RenG15021RenG15021KT746049PINAM46L, I54LV, L76V, V82AL33FL10V, I13IV, G16E, L19V, K20R, E35D, M36I, N37DE, P39PQ, K55R, R57K, Q61N, L63T, E65D, I72V, T74S, L89MF
 RenG14993RenG14993KT746021PINAM46I, I54V, L76V, V82AQ58EL10LR, T12A, K14R, I15V, G16E, E35N, M36IV, N37D, R41K, K55R, R57K, D60E, Q61D, L63T, I72T, L89MF
 RenG12947RenG12947KT743975PINAM46I, I54V, L76V, V82AV11VI, L33I, N83DL10V, I13A, K14KR, A22V, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63P, L89IF
 RenG12344RenG12344KT743372PINAM46I, I54V, L76V, V82FL33LF, Q58EL10V, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61D, I62V, L63LP, H69Y, A71AV, I72T, L89M, I93LF
 RenG12039RenG12039KT743067PINAM46I, I54V, L76V, V82F L10I, K20KR, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, I72V, P79PL, I85IV, L89MF
 RenG13470RenG13470KT744498PINAM46I, I54V, L76V, V82A L10IV, I13IV, I15V, G16E, K20T, E35D, M36I, P39T, R41K, R57K, Q61N, L63T, E65D, I72V, T74S, V77I, L89MF
 RenG11951RenG11951KT742979PINAM46I, I54V, L76V, V82FL33LF, Q58EL10V, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61D, I62V, L63LP, H69Y, A71AV, I72T, L89M, I93LF
 RenG12434RenG12434KT743462PINAM46L, I54V, L76V, V82A, L90M L10IV, I15V, G16A, K20MR, E35DN, M36IV, N37ND, R41K, K55KR, R57K, Q61N, L63P, A71V, I72IV, I93LF
 RenG13351RenG13351KT744379PINAM46MI, I54V, L76V, V82A L10V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, A71V, I72T, I93LF
 RenG12901RenG12901KT743929PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG13251RenG13251KT744279PINAM46I, L76V, V82A I15V, K20T, E34K, E35D, M36V, P39S, R41K, R57K, D60E, Q61N, I62V, L63P, T74S, L89MF
 RenG13395RenG13395KT744423PINAM46I, I54V, L76V, L90MQ58QET12K, I15V, G16E, K20T, E35D, M36I, N37E, R57K, D60E, Q61N, L63S, H69HR, L89IF
 RenG12717RenG12717KT743745PINAM46I, I54V, L76V, V82AV32VL, Q58EL10I, I15V, K20R, E35D, M36I, N37E, R57K, D60E, Q61N, L63P, I93LF
 RenG11967RenG11967KT742995PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG12087RenG12087KT743115PINAM46L, I54V, L76V, V82MQ58EL10I, I13V, I15V, K20T, E35DN, M36I, R41K, R57K, Q61N, I62V, E65D, T74S, L89MF
 RenG12368RenG12368KT743396PINAM46I, I54V, L76VG73SL10V, I15V, L19V, E35D, M36I, R41K, R57K, D60E, I62L, A71IV, V77I, I85V, L89T, Q92KF
 RenG13089RenG13089KT744117PINAM46I, I54V, L76V, V82L L10I, T12N, I15V, L19I, K20T, D25DN, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71I, V77I, I85V, L89T, Q92KF
 RenG12539RenG12539KT743567PINAM46I, I54V, L76V, I84VN83DR8X, L10I, T12I, I13A, G16E, K20R, A22V, E35D, M36I, R41K, R57K, Q61N, I72R, L89IF
 RenG11950RenG11950KT742978PINAM46I, I54V, L76VQ58ET12K, K14M, I15V, G16E, K20T, E35D, M36I, N37E, R57K, Q61N, L63R, E65D, L89MF
 RenG12499RenG12499KT743527PINAM46I, I54V, L76V, V82AL33FL10I, T12I, I13V, I15V, G16E, K20*, D29V, E35D, M36I, N37DE, R41K, K55R, R57K, Q61N, I62R, L63V, E65ED, L89MF
 RenG10514RenG10514KT741542PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, K20R, E35D, M36I, N37K, R41K, K55R, R57K, Q61N, I62IV, L63P, I72V, P79A, L89FF
 RenG11279RenG11279KT742307PINAG48V, I54V, L76V, V82A, I84VM46V, Q58EL10I, I15V, G16E, K20R, E35D, M36I, K55R, R57K, Q61N, L63C, L89IF
 RenG10265RenG10265KT741293PINAM46I, I54V, L76V, V82AL24IL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, I64IL, A71V, I72T, L89I, I93LF
 RenG11122RenG11122KT742150PINAM46L, I54V, L76V, V82AF53LL10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, A71V, I93LF
 RenG10556RenG10556KT741584PINAM46I, I54V, L76V, V82AK43TL10I, K14R, I15V, G16GA, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, I62V, L63T, H69HY, I72T, L89M, I93LF
 RenG11085RenG11085KT742113PINAM46I, I54V, L76V, V82AL24IL10V, I15V, K20R, E34Q, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I72T, L89IF
 RenG10050RenG10050KT741078PINAM46I, I54V, L76V, V82AL33FL10V, I13V, K14R, K20KR, E35D, M36I, R41K, R57K, Q61N, L63P, E65D, K70R, L89MF
 RenG11155RenG11155KT742183PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, K20R, E35D, M36I, N37D, K55R, R57K, D60E, Q61N, I62V, L63S, L89MF
 RenG10068RenG10068KT741096PINAM46I, I54V, L76V, V82AQ58EL10I, I15V, E35D, M36I, N37D, K55R, R57K, D60E, Q61N, I62V, L63S, L89MF
 RenG11735RenG11735KT742763PINAM46I, I54V, L76V, L90M L10V, I13V, I15V, K20T, E35N, M36I, R41K, R57K, D60E, Q61N, I62IV, L63P, A71I, L89I, T91S, I93LF