<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation T74P
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 8
Isolates 8
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Soares (2003)BR60BR60AY275750IDV154M46I, I54V, V82TL24I, T74PL10I, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L89MF
Baxter (2006)48-91869186-30901DQ877291PINAM46L, I54V, V82AL24I, L33F, K43T, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I64L, A71V, I72T, L89I, I93LF
 48-92509250-30908DQ877602PINAM46L, I54V, V82AV11VI, L24I, L33F, T74PL10I, I13V, G17E, L19I, K20R, E35D, M36I, R41K, R57K, Q61DN, I62V, L63T, E65D, I72T, L89MF
Dumans (2009)RENA686RENA686FJ405043IDV, NFV326M46I, I54V, V82AL24I, K43T, T74PL10I, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63C, E65D, L89MF
 RENA555RENA555FJ405127SQV, NFV, RTV, IDV, Unknown>191I54V, V82A, L90ML33F, K43T, F53L, T74PL10V, I13V, K14R, G16E, K20R, E35D, M36I, P39T, R41K, R57K, D60E, Q61N, I62V, L63H, A71I, I72V, I93LF
Jones (2012)161363161363JN670004PINAI54V, V82A, L90MF53L, T74PL10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, A71V, I93L, C95FF
 179773179773JN670525PINAM46I, I54A, V82A, L90MT74PL10I, I15V, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, I62V, L63V, A71V, L89M, I93LF
 183504183504JN670649PINAM46I, I54V, V82A, L90ML33F, K43KT, F53L, T74PL10V, I15V, K20M, E35N, M36L, N37ND, L38W, R41K, K55R, R57K, Q61N, I62V, L63P, H69R, A71V, I72V, I93LF