<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation T74P
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 41
Isolates 41
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Soares (2003)BR60BR60AY275750IDV154M46I, I54V, V82TL24I, T74PL10I, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L89MF
Baxter (2006)48-91869186-30901DQ877291PINAM46L, I54V, V82AL24I, L33F, K43T, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I64L, A71V, I72T, L89I, I93LF
 48-92509250-30908DQ877602PINAM46L, I54V, V82AV11VI, L24I, L33F, T74PL10I, I13V, G17E, L19I, K20R, E35D, M36I, R41K, R57K, Q61DN, I62V, L63T, E65D, I72T, L89MF
Waleria-Aleixo (2008)08RJ06050108RJ060501FJ591693PINAL90MT74PL10V, I15V, G16Q, K20T, E35N, M36I, P39T, R41K, R57K, D60E, Q61D, L63T, I64V, I72V, L89MF
 08RJ06057908RJ060579FJ591739PINAM46I, I50V, I54V, V82AL24I, L33F, K43T, T74PL10I, I13V, G16Q, K20R, E35D, M36I, P39A, R41K, K55R, R57K, D60E, Q61N, I62V, K70R, I72V, L89MF
 08RJ06066908RJ060669FJ591784PINAM46L, I54V, V82A, L90MT74PL10V, G17E, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63T, E65D, I72T, L89MF
Dumans (2009)RENA686RENA686FJ405043IDV, NFV326M46I, I54V, V82AL24I, K43T, T74PL10I, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63C, E65D, L89MF
Aulicino (2011)ARM522BCEARM522BCEFJ525832PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, K55R, R57K, Q61N, I62V, L63P, L89IF
Jones (2012)178038178038JN670468PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, N37NI, K55R, R57K, Q61N, I62V, L63P, L89IF
 197471197471JN671074PINAM46I, I84VL10F, F53L, T74PI13V, G16E, L19I, K20T, E35D, M36I, P39Q, K55R, R57K, D60E, Q61N, L63T, I64IV, E65D, L89MF
Diaz (2015)RenG16649RenG16649KT747677PINAM46L, I54V, V82A, L90MK43T, T74PL10IV, T12K, I13V, K14KR, I15V, K20I, E35N, M36I, R41K, Q61N, L63T, E65D, I72T, L89MF
 RenG17077RenG17077KT748105PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41PQ, R57K, Q61N, I62V, L63P, A71I, V77I, L89TF
 RenG16518RenG16518KT747546PINAM46I, I47V, I54V, V82A, L90MV11I, K43T, F53L, G73C, T74P, L89VL10V, T12K, I13A, I15V, L19I, K20I, E34Q, E35D, M36I, N37E, K55R, I62V, L63T, I72VF
 RenG16492RenG16492KT747520PINAM46L, I54V, V82AL24I, L33F, K43T, T74PL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, H69R, Q92KF
 RenG16017RenG16017KT747045PINA T74PI13V, K14R, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63PF
 RenG17021RenG17021KT748049PINAV32I, I47V, I50V, I54L, V82ML33F, K43T, T74PL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37S, R57K, Q61N, L63T, E65D, I72V, L89FF
 RenG16952RenG16952KT747980PINAM46MI, I50L, I54IV, V82VA, L90ML33LF, K43T, T74PL10V, I13V, I15V, K20V, E35DN, M36I, R41K, K55R, R57K, Q61N, L63LP, E65ED, I66IF, A71AT, I72T, L89I, T91TSF
 RenG16739RenG16739KT747767PINAM46L, I54V, V82AL24I, L33F, T74PL10IV, I13V, K20R, E35D, M36I, N37D, R41K, K55T, R57K, Q61N, I64L, L89MF
 RenG13828RenG13828KT744856PINAM46I, I47V, I54V, V82T, I84VL33F, K43T, F53L, T74PL10I, I13IV, K20R, E35D, M36I, N37ND, R41K, D60DE, Q61N, I62IV, L63P, A71V, Q92QRF
 RenG13764RenG13764KT744792PINAM46I, I54V, V82AL24I, L33F, K43T, T74PL10V, T12P, I13V, I15V, Q18QL, L19P, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, I64L, H69R, I72R, L89M, Q92KF
 RenG13858RenG13858KT744886PINAM46L, G48GS, I54V, V82A, L90ML33LF, K43T, T74PL10V, G16E, L19I, K20R, E35D, M36V, P39T, R41K, R57K, Q61D, I62V, A71V, I72R, I93LF
 RenG13955RenG13955KT744983PINAI54IV, I84VL10F, T74PI13V, I15V, K20MT, E35EDG, M36MI, N37NS, R41K, K45R, F53FI, V56VA, R57K, Q61N, I62IV, L63AV, I64V, V77VI, L89MF
 RenG13655RenG13655KT744683PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41P, K55KR, R57K, Q61N, I62V, L63P, A71I, I72IV, V77I, L89TF
 RenG15172RenG15172KT746200PINAV32I, M46I, I47V, I54M, V82A, L90ML33F, F53L, T74PL10I, I13V, G16GDE, K20R, E34A, E35D, M36I, R41K, K45KR, K55R, R57K, Q61N, L63S, C67E, I72V, V77IF
 RenG15100RenG15100KT746128PINAM46I, I50V, I54V, V82AL33F, K43T, T74P, N83DL10I, I13V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, L89IF
 RenG14197RenG14197KT745225PINAM46I, V82AL24I, K43T, T74PL10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, E65D, I72T, L89MF
 RenG15201RenG15201KT746229PINAI50L, L90MT74PL10I, K20R, E34KR, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, I62V, L63P, V77I, L89M, I93LF
 RenG14428RenG14428KT745456PINAM46L, I54V, V82AL24I, L33F, T74PL10V, I13V, K20KR, E35D, M36I, N37D, R41K, R57K, Q61N, L89MF
 RenG14313RenG14313KT745341PINAM46L, I54V, V82AL10F, L33F, T74PI13V, K20I, E35D, M36I, R41K, K55R, R57K, Q61N, E65D, L89MF
 RenG11970RenG11970KT742998PINAM46L, G48MV, I54V, V82A, L90ML33LF, K43T, T74PL10V, K20R, E35D, M36I, R41K, R57K, Q61D, I62V, L63P, A71V, I72AT, L89I, T91A, I93LF
 RenG13058RenG13058KT744086PINAM46I, I54A, V82M, L90ML33F, T74PL10I, I13V, K14R, I15V, K20R, E35D, M36I, N37DE, R41K, R57K, Q61N, L63T, I64V, H69S, L89MF
 RenG13415RenG13415KT744443PINAM46L, V82AL24I, T74PL10I, T12P, K14R, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, L89MF
 RenG12441RenG12441KT743469PINAM46L, I54V, V82A, L90MK43T, T74PL10I, I15V, L19I, K20R, E35D, M36I, R41K, K55KR, R57K, Q61D, I62V, L63P, L89LM, I93LF
 RenG12638RenG12638KT743666PINAI54V, V82A, L90ML33F, T74PL10V, I13V, K20R, E35D, M36I, R41K, R57K, Q61D, I72T, L89MF
 RenG11537RenG11537KT742565PINAI54V, V82AL33LFI, T74PL10V, T12E, I15V, L19I, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, I62V, L63P, C67CY, L89MTF
 RenG11793RenG11793KT742821PINAG48A, I54V, V82AL24I, L33F, K43T, T74P, N83DL10I, I13V, K20R, E35D, M36L, R57K, Q61D, I62V, I72R, L89MF
 RenG10941RenG10941KT741969PINAM46L, I54V, V82AL24I, L33F, T74PL10I, I13IV, I15IK, K20R, E35D, M36I, R41RK, K43S, R57K, Q61N, I62V, L63P, I64M, A71V, L89LIM, I93LF
 RenG10810RenG10810KT741838PINAM46L, I54V, V82AL24I, L33F, K43T, T74PW6L, L10V, I13V, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, I72T, L89MF
 RenG10303RenG10303KT741331PINAI50LK43T, T74PL10H, T12P, I15V, L19I, K20T, E34N, E35D, M36I, R41K, R57K, Q61N, E65D, I72TF
 RenG10321RenG10321KT741349PINAM46L, I50V, V82AV11I, L24I, L33F, K43T, F53FL, T74P, L89EIKVL10I, I13V, I15V, K20R, E35D, M36I, N37DE, R41K, R57K, Q61N, I62V, L63LP, G68GE, A71V, I93LF
 RenG11373RenG11373KT742401PINAM46MIL, I54V, V82A, L90MT74PL10I, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63P, I85IV, L89MF