<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation T74A
Rx PI-naive
IncludeMixtures No
References 8
Patients 8
Isolates 8
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Op de Coul (2000)CE97R103CE97R103AF204048None   I13V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72V, G73V, T74A, L89MF
Dilernia (2007)F043F043EF120104None   E35D, M36I, R41K, R57K, Q61N, L63PS, T74A, I93LF
Vercauteren (2009)pt7528640409048GQ400272None   L10V, T12K, I15V, K20R, E35D, M36I, N37D, R41K, K43R, I62V, L63P, H69HQ, T74A, L89MF
da Silveira (2012)BRMS33BRMS33JF342287None   L10I, I15V, E35D, M36I, R41K, R57K, Q61S, T74A, L89MF
Temereanca (2013)SR27SR27JX966504None   T12P, I15V, L19I, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, I72T, T74A, L89M, I93MF
Agyingi (2014)LB089LB089KF576438None   T12S, I15V, K20R, E35D, M36I, N37D, R41K, K43R, I62V, L63P, H69Q, T74A, L89MF
Liegler (2014)96358269635826KJ586116None   L10V, I15V, K20R, E35D, M36I, R41K, D60E, I62V, H69Q, T74A, L89MF
Verhofstede (2017)31383138MF754830None   L10V, I15V, G16E, K20R, E35D, M36I, P39S, R41K, I62V, T74A, L89MF