<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation A71T
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 82
Isolates 82
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)9764497644AY365553PINAV32I, M46I, I47V, V82AL24I, L89VL10I, T12N, I15V, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, A71T, V77I, I93LF
 9901099010AY365591PINAM46L, I54V, V82AL24IL10I, T12I, I15V, K20IMR, E35D, M36I, N37D, R41K, Q61D, L63P, I64V, H69Y, A71T, I72TF
 103620103620AY365684PINAD30N, L90MN88DI13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63D, A71T, I72TF
 104518104518AY365706PINAM46ML, I54V, V82C, L90M L10I, I15V, K20R, E35D, M36I, N37V, R41RK, K55N, R57K, D60E, Q61N, I62V, L63P, A71T, I72T, I85V, I93LF
 105988105988AY365741PINAI54V, L90M L10I, I13V, I15V, G16E, K20T, E35D, M36I, P39S, R41K, R57K, Q61N, L63P, A71T, I72TF
 109072109072AY365802PINAM46I, I84V, L90M L10I, I13V, I15V, Q18H, L19I, K20I, E35D, M36I, N37K, R41K, R57K, D60DE, Q61N, L63P, G68E, A71T, I72EF
 112644112644AY365862PINAI54V, V82A, L90M L10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, L63P, A71T, I93LF
 124260124260AY366031PINAI54V, V82VF, I84IVF53LL10V, K20R, E35D, M36I, R41K, K43KR, K45KEIV, R57K, Q61N, I64V, A71T, I93ILF
Non-B Workgroup (2005)PL36995591 Unknown, LPV>112M46L, G48V, I54V, V82A, L90ML33F, K43TL10V, I15V, G16E, K20M, E35N, M36I, N37ND, R57K, Q61D, G68E, H69R, A71T, I72R, L89I, I93LF
 PL4051769351 IDV, NFV241L90M L10I, I15V, G17D, K20T, E35D, M36I, R57K, Q61H, L63P, I64V, A71T, I72V, L89M, I93LF
Rodrigues (2005)BLF_Pat12BR03SP110AY643158IDV, NFV271L90M L10I, I15L, L19I, K20I, E35D, M36I, N37S, R41K, R57K, Q61N, L63P, I64V, A71T, I72T, I93LF
 BLF_Pat35BR03SP71AY643177IDV, NFV269I54V, L90M L10V, I13V, I15V, K20T, E35D, M36I, N37T, R41K, R57K, Q61N, A71T, T74S, L89IF
 BLF_Pat41BR02SP138AY643137Unknown, NFV>11D30N, M46MLN88DL10V, I13V, I15V, K20R, E35D, M36I, N37NI, R41K, K45KR, R57K, Q61D, A71T, I72TF
Baxter (2006)48-10901090-30717DQ877345PINAL90LM K14R, I15V, K20T, E35G, M36I, R41K, R57K, Q61N, A71T, I72T, T74TA, V82I, I85V, Q92QRF
 48-11571157-30918DQ877419PINAI54V, V82AN88DL10I, I15V, K20R, E35D, M36I, R41K, K43KR, K45R, R57K, Q61D, L63P, A71T, I93LF
 48-12181218-30701DQ877756PINAM46I, I54V, V82A, L90ML33F, G73TL10V, T12S, I13V, K14T, I15V, K20T, E35D, M36I, P39T, R41K, R57K, Q61N, I62V, L63P, A71T, I72T, I93LF
Aulicino (2011)ARM804TJXARM804TJXFJ525841PINAD30NN88DT12M, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61D, A71T, I72T, T74S, I85VF
 ARN815QLSARN815QLSFJ525866PINAI54V, L90M I13V, I15V, K20T, E35D, M36I, P39Q, R57K, Q61N, L63P, A71T, V82I, L89I, Q92K, I93LF
 59-O184CME59-O184CMEHQ158162PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61D, A71T, I72T, I93LF
 662-N701DLC662-N701DLCHQ158179PINAL90M K14R, I15V, L19V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, A71T, T74S, Q92K, I93LF
 352-O64MD352-O64MDHQ158193PINAD30NN88DT12K, I13V, I15V, E35D, M36I, N37D, R41K, R57K, Q61N, A71T, I72T, V75IF
 2125-K3102125-K310HQ158233PINAD30NN88DI15V, K20T, E35D, M36I, R41K, R57K, Q61D, L63P, A71T, I93LF
Jones (2012)128819128819JN669455PINAV82L, L90M I15V, G17E, K20T, E35N, M36I, R57K, Q61D, I62V, L63P, A71T, I72R, I93LF
 136173136173JN669555PINAI54V, I84V, L90M K14R, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71T, I72TF
 143766143766JN669646PINAD30NN88DI15V, K20T, E35N, M36I, P39PS, R41K, R57K, Q61N, A71T, I72IT, T74S, I93LF
 150685150685JN669753PINAM46I, I54LV, V82C, L90MG73TL10IV, I13M, I15V, G16E, K20V, E35NS, M36I, R41K, K55KR, R57K, Q61N, I62V, L63C, A71T, I72T, I93LF
 151017151017JN669756PINAL90M L10V, I13V, I15V, K20V, E35N, M36I, R41K, R57K, Q61N, I62IV, L63LP, A71T, I72T, T74SF
 159510159510JN669955PINAI54V, V82A, L90MK43TL10I, I15V, G16E, K20M, E35D, M36I, R41R_R, R57K, Q61N, I62L, L63C, A71T, I72T, T74S, I85VF
 160102160102JN669969PINA  I15V, K20KR, M36MI, R41K, R57K, Q61N, A71T, I72EV, V77I, I93LF
 160560160560JN669981PINAM46I, I54V, L76V, L90ML89VL10V, I13V, I15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KF
 161994161994JN670024PINAM46L, I54V, V82AL24I, K43KTL10V, I15V, G16E, L19I, K20R, M36I, K55R, R57K, Q61N, L63N, A71T, I72T, T91SF
 164777164777JN670081PINAI54V, V82A, L90ML33F, G73SL10I, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, A71T, I72RF
 172771172771JN670300PINAI54A, I84V L10I, I13V, I15V, L19I, K20R, E34N, E35D, M36I, R41K, R57K, Q61N, L63P, A71T, I72T, I93LF
 173204173204JN670315PINAM46I, I54IL, V82C, L90MG73TL10V, I13M, I15V, G16E, K20V, E35NS, M36I, R41K, K55R, R57K, Q61N, I62V, L63C, A71T, I72T, I93LF
 173206173206JN670316PINAM46I, N88S, L90M I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71T, I72T, I93LF
 177362177362JN670438PINA  T12I, I15V, E35D, M36I, N37D, R57K, Q61S, I62V, A71T, V77I, I93LF
 179226179226JN670504PINAD30N, I54V, L90MV11VI, Q58E, N88DI15V, K20IMT, E35NS, M36I, N37D, R41K, R57K, Q61N, L63P, A71T, I72TF
 179245179245JN670506PINAM46I, I50V, I54V, V82AL33LFL10I, T12TM, I15V, G16E, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, A71T, I72RF
 180609180609JN670551PINA  I15V, R41K, R57K, Q61N, A71T, I72E, V77I, I93LF
 184640184640JN670684PINAL90M I13IV, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, A71T, I72TF
 191236191236JN670816PINAM46L, I54V, V82A, I84IVL24I, K43T, F53FLL10IV, I15V, G16E, L19I, K20R, E35D, M36I, K55R, R57K, Q61N, L63N, I64IV, A71T, I72T, T74TA, T91SF
 198155198155JN671105PINA  I15V, G17E, E35D, M36I, R41K, R57K, Q61D, A71T, I72KR, I93LF
 198184198184JN671110PINAD30NN88DI13V, K14R, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63S, A71T, I72M, Q92RF
 198824198824JN671136PINA  L10V, T12AP, K14KR, I15V, G17E, K20KM, E35D, M36I, R41K, R57K, Q61N, L63T, A71T, I72T, I93LF
 199553199553JN671175PINA  L10LI, I15V, E35D, M36I, P39PT, R41K, R57K, Q61D, A71T, I72IMR, I93LF
 202696202696JN671286PINA  L10I, T12P, E35D, M36I, N37D, R41K, R57K, D60E, Q61D, L63S, E65D, A71T, I72IT, V77I, I93LF
 206318206318JN671397PINAM46L, I54V, V82A, I84VV11I, L24I, L33LF, K43TL10I, I15V, G16E, L19I, K20R, E35D, M36IV, K55R, R57K, Q61N, L63N, A71T, I72T, T91SF
 207053207053JN671419PINAM46L, I54V, V82A, L90MG73SL10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, A71T, I93LF
Diaz (2015)RenG17206RenG17206KT748234PINAM46I, I47V, I54V, V82A, L90ML33F, F53L, Q58EL10I, I13V, Q18IL, L19V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I66F, A71T, I72IM, L89I, Q92KF
 RenG15620RenG15620KT746648PINAM46I, I54V, L76V, V82A, L90M L10I, I13V, I15IV, G16E, K20I, E35N, M36I, N37NS, R41RK, K55R, R57K, Q61N, L63H, A71T, I72V, L89I, T91SF
 RenG15688RenG15688KT746716PINAN88S L10I, I15V, K20T, E35D, M36I, P39Q, R41K, R57K, Q61N, L63A, A71T, I85VF
 RenG16180RenG16180KT747208PINA F53L, G73SL10V, I13V, I15V, K20T, E35D, M36I, N37T, R41K, K55HN, R57K, Q61N, L63P, A71T, T74S, V77I, Q92KF
 RenG16234RenG16234KT747262PINAM46L, I54V, V82AK43TL10V, I15V, K20R, E35D, M36I, R57K, L63P, H69K, A71TF
 RenG17429RenG17429KT748457PINAI50L K14R, I15V, K20T, E35D, M36I, N37T, R41K, K45R, R57K, D60DE, Q61N, H69I, A71T, I72T, V77I, I93ILF
 RenG16312RenG16312KT747340PINAM46L, I47A, L90M I13V, I15V, K20MT, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71T, I72T, V82I, L89I, I93LF
 RenG14245RenG14245KT745273PINAM46I, G48GA, I54V, V82AL33I, F53FL, N83DL10I, I13V, K20R, A22V, E35D, M36I, N37T, R41K, R57K, Q61N, I62V, L63AP, A71T, I72T, L89IF
 RenG15020RenG15020KT746048PINA  I15V, K20T, E35D, M36I, R41K, K45R, K55R, R57K, Q61D, L63P, A71T, I72T, L89TF
 RenG14597RenG14597KT745625PINAM46L, I54V, V82AL33I, K43T, F53L, N83DL10I, I13V, K20R, A22V, E35D, M36I, R41K, K55R, R57RK, Q61N, A71T, I72T, T74AS, L89I, T91SF
 RenG14436RenG14436KT745464PINAM46L, G48V, I54V, V82AL24IL10V, I15V, L19I, K20R, E35D, M36I, N37D, R41K, F53Y, K55R, R57K, D60E, Q61E, I62V, L63P, A71T, I72T, T74TA, L89I, T91SF
 RenG14383RenG14383KT745411PINAI54V, L90ML33I, F53L, N83DL10I, I13V, A22V, E34EAKT, E35D, M36I, N37D, R41K, D60E, Q61N, I62V, A71T, L89IF
 RenG13653RenG13653KT744681PINAL90M T12K, I15V, L19V, K20T, E35N, M36I, N37E, P39Q, R41K, K43I, R57K, Y59F, D60S, Q61D, L63P, A71TF
 RenG13654RenG13654KT744682PINAM46MI, I54V, V82AL24LI, N88NDL10I, T12DE, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71T, I85IV, Q92QRF
 RenG14541RenG14541KT745569PINAD30N, M46MI, I50LL33I, N88DT12E, L19V, K20R, E21EK, E35D, M36I, N37IT, R41K, R57K, Q61D, L63P, I66IV, A71T, I93LF
 RenG13959RenG13959KT744987PINAD30N, L90ML33LI, N88DL10Y, I15V, K20T, E35DN, M36I, N37D, R41K, R57K, Q61N, I62V, A71T, T74S, V77I, I85V, L89T, Q92QKRF
 RenG14080RenG14080KT745108PINAN88S L10LV, I13V, K20T, E35D, M36I, R41K, R57K, Q61N, A71T, L89T, Q92QKF
 RenG12347RenG12347KT743375PINAD30N, M46I, L90MF53L, N88DL10V, I13V, I15V, K20R, E35D, M36I, N37T, P39Q, K55R, R57K, D60E, Q61D, I62V, L63P, A71T, I72TF
 RenG13102RenG13102KT744130PINAL90M L10V, I13V, I15V, K20T, E35D, M36I, R41K, R57RK, Q61N, G68E, A71T, L89IF
 RenG12245RenG12245KT743273PINAV32I, M46I, I47V, I54LF53LL10I, I15V, K20T, E35D, M36I, P39T, R57K, D60E, Q61D, I62V, L63E, A71T, I72T, L89MF
 RenG12608RenG12608KT743636PINAI54V, V82A, L90ML33FL10V, I13V, I15V, K20T, E35D, M36IL, R41K, R57K, Q61N, I62IV, L63DE, A71T, I72T, L89IF
 RenG13129RenG13129KT744157PINAM46L, I54V, V82A, L90MN88DL10V, I13K, I15G, K20I, E35N, M36I, L38F, R41K, R57K, Q61H, L63I, A71T, T74S, L89I, Q92KF
 RenG11186RenG11186KT742214PINAD30N, M46I, L90MF53L, N88DL10V, I13V, I15V, K20R, E35D, M36I, N37T, P39Q, K55R, R57K, D60E, Q61D, I62V, L63P, A71T, I72TF
 RenG10656RenG10656KT741684PINAD30N, M46LL23I, F53L, Q58E, N88DL10I, T12I, I13V, I15V, G16E, K20T, E35D, M36V, P39S, R41K, R57K, Q61N, I62V, A71T, I72R, V77I, L89TF
 RenG11018RenG11018KT742046PINAI54L, N88S L10V, I13V, K20R, E34A, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, A71T, I72TF
 RenG11470RenG11470KT742498PINAI54V, V82A, L90M L10I, I13V, K20M, L33L_L, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, A71T, L89I, Q92KF
 RenG10926RenG10926KT741954PINAM46L, I54V, V82A, L90MV11VI, K43KT, F53FL, G73SL10I, T12N, I15V, L19IMT, K20I, E35N, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, H69Y, A71T, I72T, I85IVF
 RenG10116RenG10116KT741144PINA  L10I, T12TA, K14R, I15V, L19Q, E35D, M36I, N37D, R41K, R57K, Q61N, L63IT, A71T, I72T, I93LF
 RenG10490RenG10490KT741518PINAD30N, M46L, I54V, V82A, L90ML33F, N88DL10I, I13V, I15V, K20R, E35D, M36I, N37T, P39T, R41K, R57K, Q61N, I62V, L63P, A71T, I72M, I93LF
 RenG10845RenG10845KT741873PINAD30N, M46IL23I, L33I, F53L, N88DR8RQ, L10I, I15IV, K20T, E35N, M36I, N37NS, R41K, K45Q, R57K, D60E, Q61N, L63D, I66V, A71T, V77VI, I93LF
 RenG11102RenG11102KT742130PINA N88DI15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63N, A71TF
 RenG11372RenG11372KT742400PINA L23IL10I, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, A71T, I72T, V77I, L89T, I93LF
 RenG10384RenG10384KT741412PINA  K14R, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, A71T, L89TF
 RenG10048RenG10048KT741076PINAI54V, V82AL33I, K43T, F53L, N83DI13V, G17A, Q18H, K20R, A22V, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, A71T, I72T, T74A, L89I, T91S, Q92HF