<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63V
Rx PI-naive
IncludeMixtures No
References 25
Patients 33
Isolates 33
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Vergne (2000)LVMP1443LVMP1443AJ287042None   L10V, I13V, K14T, I15V, L19Q, K20R, E35D, M36I, R57K, L63V, L89MF
Brindeiro (2003)BRP2156BRP2156AY213467None   K14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63V, V77I, L89MF
Kijak (2004)3163MN02CM.3163AY371160None   L10V, I15V, K20R, E35D, M36I, N37H, R41K, I62V, L63V, K70Q, I72T, L89MF
Machado (2004)cs139cs139AY313305None   T12D, K14R, I15V, G16E, L19T, E35D, M36I, P39Q, R41K, R57K, Q61N, L63V, I72T, V77I, L89M, C95SF
Arien (2005)VI64VI64DQ177219None   I15V, E35D, M36I, R41K, R57K, I62V, L63V, I72V, T74S, L89MF
Holguin (2005)0007110302_71103AY248334None   L10V, T12P, K14R, E35D, M36I, R41K, R57K, L63V, T74S, L89MF
Vidal (2006)NV_KTB22002.KTB220AM040988None   T12M, I15V, L19Q, E35D, M36I, N37E, R41K, R57K, L63V, L89MF
Eyer-Silva (2007)BRSAP1304BRSAP13DQ899709None   I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, I72T, L89MF
Bartolo (2009)HDC24001AOHDC240EU068232None   L10I, I13V, G16E, E35D, M36I, P39Q, R41K, R57K, I62V, L63V, E65D, T74S, L89MF
Cardoso (2009)BRGO3146BRGO3146FJ594178None   I15V, K20R, E35D, M36I, R41K, R57K, Q61D, L63V, E65D, I72R, V82IF
Koyalta (2009)10TCHAD-10FJ688176None   K14R, I15V, L19Q, K20R, E35D, M36I, R41K, R57K, L63V, I64M, E65D, L89MF
 75TCHAD-75FJ688205None   L10V, K14I, I15V, L19Q, K20R, E35D, M36I, R57K, L63V, L89MF
Mintsa-Ndong (2009)MKK24MKK24AM903431None   L10V, I13V, K14IT, I15V, G16GE, L19Q, K20R, E35D, M36I, R57K, L63V, L89MF
Aghokeng (2011)HJ1632HJ1632JN639525None   L10I, I13V, I15V, K20R, E35D, M36L, I62V, L63V, I64M, H69Q, L89MF
El Annaz (2011)699699HQ393242None  Q58EL10I, K14T, I15V, L19Q, K20R, E35D, M36I, R57K, L63V, H69Q, L89MF
Kousiappa (2011)CY191CY191JF683744None   L10I, T12K, I15V, L19I, E35D, M36I, R41K, K43R, R57K, L63V, E65DF
Santos (2011)J197J197_PR_RTJN010604None   L10V, T12K, I15V, E35D, M36I, R41K, Q61D, L63V, E65DF
 J218J218_PRJN010630None   L10V, T12K, I15V, E35D, M36I, R41K, K55R, Q61D, L63V, E65DF
Ferreira (2013)BR09SP281BR09SP281HM534144None   L10IV, T12N, I15V, M36I, R41K, Q61N, L63V, V75VI, I93LF
 BR09SP363BR09SP363HM534189None   L10I, T12R, I13V, L19V, E35D, M36I, R41K, R57K, Q61N, L63V, L89MF
Frentz (2013)EHR-86876EHR-86876JX301011None   L10LI, T12K, I15V, L19I, E35D, M36I, R41K, K43R, R57K, L63V, E65DF
 EHR-98971EHR-98971JX301153None   L10V, I15V, E35D, M36I, R41K, R57K, I62V, L63V, E65D, T74S, L89MF
Temereanca (2013)SR109SR109 None   L10V, E35D, M36I, R41K, R57K, I62V, L63V, T74S, L89MF
Alexiev (2015)11BG145811BG1458KJ765561None   K14N, L19T, K20R, E35D, M36I, R41K, R57K, I62V, L63V, E65D, T74S, L89MF
 11BG78111BG781KJ765587None   L10I, I13V, I15V, E35D, M36I, R41K, R57K, I62V, L63V, I64IM, L89MF
de Lourdes Teixeira (2015)9RJ1002159RJ100215 None   I15V, G17E, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, L63V, E65D, I72E, L89MF
Guimaraes (2015)RDSPR175RDSPR175KT355962None   T12K, G17E, L19I, K20R, M36I, R41K, R57K, Q61N, L63V, E65D, K70RF
 RDSPE091RDSPE091KT355943None   E35D, M36I, R41K, R57K, Q61N, L63V, E65D, H69Y, I72T, L89MF
 RDSPE097RDSPE097KT355944None   E35D, M36I, R41K, R57K, Q61N, L63V, E65D, H69Y, I72T, L89M, N98KF
Darcissac (2016)P28VBXFP28VBXFKU052741None   E35D, M36I, R41K, R57K, Q61N, L63V, E65D, L89MF
Lam (2016)1704200317042003KR867783None   T12K, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, L63V, E65D, I72TF
Lima (2016)09PE18809PE188KX021015None   L10I, I15V, G16E, E35D, M36I, R41K, K45R, R57K, Q61N, L63V, I72T, P81T, G86W, R87KF
 08PE06808PE068KX020993None   T12M, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, I72E, L89MF