<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63V
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 73
Isolates 73
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Brindeiro (2002)TVGG3TVGG3AY145819NFV30I54IV, V82VA L10LV, I15V, L19I, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, H69Y, I72T, L89MF
Gomez-Carrillo (2004)9432694326AY365498PINAV82AG L10I, T12TP, I15V, K20KR, T26TP, E35D, M36I, N37D, R41K, K43KN, R57K, Q61N, L63V, I72T, I93L, C95CGF
 9714997149AY365542PINAI54A, V82F, L90M Q7QH, L10I, T12TP, K20R, E35D, M36I, R41K, K43KN, R57K, Q61N, L63V, I64V, A71V, I72T, T74S, I93LF
 9746897468AY365549PINAM46L, I54V, V82AL24IQ7QH, L10V, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, T74SF
 102999102999AY365664PINA  L10I, T12E, I15V, E35D, M36I, R41K, R57K, Q61D, L63V, I72T, I93LF
 103279103279AY365676PINAM46I, I54S, V82AL24I, K43TL10I, T12P, I15V, L19I, K20M, E34K, E35D, M36I, R57K, Q61N, L63V, I64V, I72T, T74S, I85VF
 118805118805AY365959PINA  L10V, K14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63VF
 120879120879AY365992PINAM46I, I54V, V82AL24IL10V, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, T74SF
 123398123398AY366021PINA  T12N, I15V, L19I, E35D, M36I, R41K, R57K, Q61D, L63V, E65DF
Machado (2004)cs199cs199AY313361RTV75M46L, I54V, V82AL24IL10V, I15V, G16E, L19I, K20R, E35D, M36I, R57K, Q61D, L63V, E65DF
Rodrigues (2005)BR0208200AY441803NFV, SQV, RTV57  K14R, I15X, G16E, E35D, M36I, P39T, R41K, R57K, Q61N, L63V, L89MF
 BLF_Pat21BR02SP235AY643144IDV, Unknown>165I54V, V82A, L90M L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, A71V, I72T, L89I, Q92K, I93LF
 BLF_Pat31BR03SP35AY643173NFV, RTV33  T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63V, V82I, L89MF
Baxter (2006)48-10891089-30716DQ877344PINAM46L, I54V, L90M T12N, I15V, G16GE, K20RT, E35D, M36V, P39S, R41K, R57K, Q61N, I62V, L63V, A71I, I72T, V77VI, I93LF
Eyer-Silva (2007)BRSAP0704BRSAP07DQ899704LPV22  I15V, E35D, M36I, N37D, R41K, R57K, Q61N, L63V, I64M, L89MF
 BRSQ3904BRSQ39EF042646IDV, LPV   I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63V, E65D, I72TF
Dumans (2009)RES28_02RES28_02FJ405158IDV, NFV, RTV, APV139M46L, I54V, V82AL33FL10I, G17D, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, L89MF
 RENA166RENA166FJ405176RTV, NFV, SQV, APV, IDV173  L10V, I15V, G16E, E35D, M36I, P39T, R41K, R57K, Q61N, L63V, I72T, L89MF
Aulicino (2011)ARN926MRDARN926MRDFJ525867PINAD30NN88DL10V, T12I, I15V, K20A, E35N, M36I, N37D, R41K, K45R, R57K, Q61N, L63V, A71V, I72TF
Jones (2012)127721127721JN669442PINA  L10V, T12N, I15V, M36I, R41K, R57K, Q61N, L63V, K70RF
 137235137235JN669561PINA  L10V, T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63V, I72EF
 141850141850JN669608PINA  E35D, M36I, R41K, R57K, Q61N, L63V, E65D, I72TF
 157841157841JN669901PINA  I15V, E35D, M36I, R41K, K43R, R57K, D60E, Q61D, L63V, I72TF
 164634164634JN670080PINAD30DN I15V, G17DE, K20KR, E35D, M36I, R57K, Q61N, L63V, E65DF
 167092167092JN670143PINA  L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, C67F, P79S, I93LF
 172419172419JN670289PINA  R8R*, L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, C67F, P79S, I93LF
 175336175336JN670353PINAD30NN88DI13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63V, I64L, I72E, T74S, L89M, I93LF
 177469177469JN670442PINA  L10I, T12DEKN, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, I62IV, L63V, E65D, I72T, I93LF
 178103178103JN670470PINA  L10V, T12K, I13V, G16E, L19LP, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63V, E65ED, I72T, L89MF
 179773179773JN670525PINAM46I, I54A, V82A, L90MT74PL10I, I15V, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, I62V, L63V, A71V, L89M, I93LF
 185104185104JN670697PINA  T12I, I15V, G16E, E35D, M36I, N37E, R41K, R57K, Q61N, L63V, E65D, I72TF
 190546190546JN670800PINAD30N, L90MN88D, L89LVT12K, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63V, T74S, I93LF
 196326196326JN671020PINA  T12E, I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63V, I72TF
 201442201442JN671225PINAI54V, V82A, L90MF53FLL10IV, I15V, G16E, K20R, E35D, M36I, P39PS, R41K, R57K, D60E, Q61N, I62V, L63V, A71V, I72V, I93LF
Diaz (2015)RenG15609RenG15609KT746637PINAI50L, N88SL33FT12N, I13IV, I15V, L19I, K20I, E35N, M36I, N37D, R41K, R57K, Q61N, L63V, I64V, I72V, T74TA, V77VI, L89MF
 RenG17165RenG17165KT748193PINAV32I, M46L, I47IV, I54LV, V82A, I84VL24I, L33FL10I, I13V, G17D, L19I, K20R, E35D, M36I, K43I, R57K, Q61N, L63V, E65D, I72T, T74S, V77IL, L89MF
 RenG15922RenG15922KT746950PINA  I15V, Q18E, K20R, E35D, M36I, R41K, R57K, Q61N, I62IV, L63V, I72T, I93ILF
 RenG16167RenG16167KT747195PINA  K14R, I15V, K20KR, E35D, M36I, R41K, R57K, Q61N, L63V, G68E, L89MF
 RenG16151RenG16151KT747179PINAV32I, M46I, I47V, I54A, V82AL76ML10I, I15V, L19I, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, I62IV, L63V, I64L, A71I, I72T, L89M, I93LF
 RenG17455RenG17455KT748483PINAV32I, I47A, V82A L10V, I15V, L19LI, K20R, E35D, M36I, N37D, K45R, Q61N, L63V, I72E, L89MF
 RenG15582RenG15582KT746610PINA  L10V, T12V, I15V, G16E, E35D, M36I, P39T, R41K, R57K, Q61N, I62V, L63V, I64IM, I72V, L89MF
 RenG16858RenG16858KT747886PINAD30NN88DT12I, I13V, I15V, Q18E, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, I64L, E65ED, I72V, L89MF
 RenG16619RenG16619KT747647PINAM46I, I50V, I54V, N88S L10I, I15V, K20T, E35D, M36I, R41K, R57K, Q61D, I62V, L63V, I64V, T74A, L89M, I93LF
 RenG16102RenG16102KT747130PINAI50L L10I, K20R, E35D, M36I, N37D, R41K, K45N, R57K, Q61N, L63V, E65D, I72T, L89M, I93LF
 RenG15630RenG15630KT746658PINAM46I, I54V, V82AL24IL10V, I15V, L19I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63V, I72E, L89MF
 RenG15303RenG15303KT746331PINA  I15V, E35D, M36I, R41K, K45KR, R57K, Q61N, L63V, I72T, L89MF
 RenG15253RenG15253KT746281PINA  I13V, I15V, E35D, M36I, R41K, R57K, Q61N, L63VF
 RenG13942RenG13942KT744970PINAN88S L10V, G16E, K20R, E35D, M36V, P39S, K45R, R57K, Q61D, L63V, E65D, I72V, L89MF
 RenG13891RenG13891KT744919PINA  L10I, G17D, K20R, E35D, M36I, R41K, Q61N, L63V, E65D, I72T, L89M, I93LF
 RenG14710RenG14710KT745738PINA  L10I, I15V, L19Q, E35D, M36I, R41K, K43R, R57K, Q61N, L63V, E65ED, I72T, V82I, I93LF
 RenG14293RenG14293KT745321PINAM46L, I54V, L76V, V82AL33FL10V, I13V, G16E, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63V, E65D, I72T, T74A, L89MF
 RenG14220RenG14220KT745248PINA  I15*, G16E, E35D, M36I, R41K, R57K, Q61N, L63V, I72EF
 RenG14133RenG14133KT745161PINA  L10V, I15V, K20KR, E35D, M36I, R41K, Q61N, L63VF
 RenG15336RenG15336KT746364PINA  L10V, I15V, E35D, M36I, R41K, K43KR, R57K, Q61N, L63V, I72MV, T74S, I93LF
 RenG13781RenG13781KT744809PINAM46I, I50V, I54V, L76V L10I, I15V, K20T, E35N, M36I, R41K, R57K, Q61D, I62V, L63V, I64IV, A71V, T74A, V82I, L89M, I93LF
 RenG14374RenG14374KT745402PINA  K14R, I15V, E35D, M36I, R41K, R57K, Q61D, L63V, E65D, I72TF
 RenG14392RenG14392KT745420PINA  I15V, E35D, M36I, N37D, R41K, R57K, Q61N, L63V, I64MF
 RenG11813RenG11813KT742841PINA  L10I, T12S, E35D, M36I, P39PQ, R41K, R57K, Q61N, L63V, H69QF
 RenG12852RenG12852KT743880PINA  L10I, K14KR, E35D, M36I, R41K, R57K, Q61N, L63V, E65ED, I72T, V77VI, L89MF
 RenG12057RenG12057KT743085PINAM46I, I54V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, L63V, E65D, I72T, L89MF
 RenG12202RenG12202KT743230PINA  T12N, K14T, I15V, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, I72IT, L89MF
 RenG12653RenG12653KT743681PINA  L10V, T12K, I15V, G16GE, E35D, M36I, P39T, R41K, R57K, D60E, Q61D, L63V, L89MF
 RenG12429RenG12429KT743457PINA  I13V, K14Q, I15V, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, L63V, E65D, L89MF
 RenG12499RenG12499KT743527PINAM46I, I54V, L76V, V82AL33FL10I, T12I, I13V, I15V, G16E, K20*, D29V, E35D, M36I, N37DE, R41K, K55R, R57K, Q61N, I62R, L63V, E65ED, L89MF
 RenG10066RenG10066KT741094PINAM46L, I54V, V82AL24I, K43TL10V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, K55KR, R57K, Q61N, I62V, L63V, E65D, T74A, L89MF
 RenG11035RenG11035KT742063PINAV82A L10V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, K70R, I72T, R87RKF
 RenG10407RenG10407KT741435PINA  L10V, T12I, I15V, E35D, M36I, R41K, R57K, Q61N, L63V, I72IT, V77VI, L89MF
 RenG11226RenG11226KT742254PINAV32I, I54A, V82AL24I, K43TL10I, K20R, L33*, E34K, E35D, M36I, R41K, R57K, Q61N, L63V, I64V, T74SF
 RenG10341RenG10341KT741369PINA  L10I, T12Q, K14KR, I15V, G17E, E35D, M36I, R41Q, R57K, Q61N, L63V, E65D, I93LF
 RenG11594RenG11594KT742622PINA  T12N, I15L, L19I, E35D, M36I, R41K, R57K, Q61N, L63V, L89MF
 RenG10660RenG10660KT741688PINA  I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, L89MF
 RenG10324RenG10324KT741352PINAV32I, I47A L10I, T12S, I15V, L19I, K20T, E35D, M36I, N37S, R41N, R57K, Q61DN, L63V, H69HY, I72T, V82I, L89M, I93LF
 RenG10784RenG10784KT741812PINA  L10I, T12E, K14R, I15V, M36I, R41K, R57K, Q61N, L63V, I93LF