<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63V
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 34
Isolates 34
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Brindeiro (2002)TVGG3TVGG3AY145819NFV30I54IV, V82VA L10LV, I15V, L19I, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, H69Y, I72T, L89MF
Gomez-Carrillo (2004)9432694326AY365498PINAV82AG L10I, T12TP, I15V, K20KR, T26TP, E35D, M36I, N37D, R41K, K43KN, R57K, Q61N, L63V, I72T, I93L, C95CGF
 9714997149AY365542PINAI54A, V82F, L90M Q7QH, L10I, T12TP, K20R, E35D, M36I, R41K, K43KN, R57K, Q61N, L63V, I64V, A71V, I72T, T74S, I93LF
 9746897468AY365549PINAM46L, I54V, V82AL24IQ7QH, L10V, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, T74SF
 102999102999AY365664PINA  L10I, T12E, I15V, E35D, M36I, R41K, R57K, Q61D, L63V, I72T, I93LF
 103279103279AY365676PINAM46I, I54S, V82AL24I, K43TL10I, T12P, I15V, L19I, K20M, E34K, E35D, M36I, R57K, Q61N, L63V, I64V, I72T, T74S, I85VF
 118805118805AY365959PINA  L10V, K14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63VF
 120879120879AY365992PINAM46I, I54V, V82AL24IL10V, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, T74SF
 123398123398AY366021PINA  T12N, I15V, L19I, E35D, M36I, R41K, R57K, Q61D, L63V, E65DF
Machado (2004)cs199cs199AY313361RTV75M46L, I54V, V82AL24IL10V, I15V, G16E, L19I, K20R, E35D, M36I, R57K, Q61D, L63V, E65DF
Rodrigues (2005)BR0208200AY441803NFV, SQV, RTV57  K14R, I15X, G16E, E35D, M36I, P39T, R41K, R57K, Q61N, L63V, L89MF
 BLF_Pat21BR02SP235AY643144IDV, Unknown>165I54V, V82A, L90M L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, A71V, I72T, L89I, Q92K, I93LF
 BLF_Pat31BR03SP35AY643173NFV, RTV33  T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63V, V82I, L89MF
Baxter (2006)48-10891089-30716DQ877344PINAM46L, I54V, L90M T12N, I15V, G16GE, K20RT, E35D, M36V, P39S, R41K, R57K, Q61N, I62V, L63V, A71I, I72T, V77VI, I93LF
Eyer-Silva (2007)BRSAP0704BRSAP07DQ899704LPV22  I15V, E35D, M36I, N37D, R41K, R57K, Q61N, L63V, I64M, L89MF
 BRSQ3904BRSQ39EF042646IDV, LPV   I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63V, E65D, I72TF
Dumans (2009)RES28_02RES28_02FJ405158IDV, NFV, RTV, APV139M46L, I54V, V82AL33FL10I, G17D, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, L89MF
 RENA166RENA166FJ405176RTV, NFV, SQV, APV, IDV173  L10V, I15V, G16E, E35D, M36I, P39T, R41K, R57K, Q61N, L63V, I72T, L89MF
Aulicino (2011)ARN926MRDARN926MRDFJ525867PINAD30NN88DL10V, T12I, I15V, K20A, E35N, M36I, N37D, R41K, K45R, R57K, Q61N, L63V, A71V, I72TF
Jones (2012)127721127721JN669442PINA  L10V, T12N, I15V, M36I, R41K, R57K, Q61N, L63V, K70RF
 137235137235JN669561PINA  L10V, T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63V, I72EF
 141850141850JN669608PINA  E35D, M36I, R41K, R57K, Q61N, L63V, E65D, I72TF
 157841157841JN669901PINA  I15V, E35D, M36I, R41K, K43R, R57K, D60E, Q61D, L63V, I72TF
 164634164634JN670080PINAD30DN I15V, G17DE, K20KR, E35D, M36I, R57K, Q61N, L63V, E65DF
 167092167092JN670143PINA  L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, C67F, P79S, I93LF
 172419172419JN670289PINA  R8R*, L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, C67F, P79S, I93LF
 175336175336JN670353PINAD30NN88DI13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63V, I64L, I72E, T74S, L89M, I93LF
 177469177469JN670442PINA  L10I, T12DEKN, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, I62IV, L63V, E65D, I72T, I93LF
 178103178103JN670470PINA  L10V, T12K, I13V, G16E, L19LP, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63V, E65ED, I72T, L89MF
 179773179773JN670525PINAM46I, I54A, V82A, L90MT74PL10I, I15V, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, I62V, L63V, A71V, L89M, I93LF
 185104185104JN670697PINA  T12I, I15V, G16E, E35D, M36I, N37E, R41K, R57K, Q61N, L63V, E65D, I72TF
 190546190546JN670800PINAD30N, L90MN88D, L89LVT12K, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63V, T74S, I93LF
 196326196326JN671020PINA  T12E, I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63V, I72TF
 201442201442JN671225PINAI54V, V82A, L90MF53FLL10IV, I15V, G16E, K20R, E35D, M36I, P39PS, R41K, R57K, D60E, Q61N, I62V, L63V, A71V, I72V, I93LF