<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63T
Rx >= 1 PI
IncludeMixtures No
References 16
Patients 131
Isolates 144
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Masciotra (2000)SM49SM49AF221052PINA  L10I, E35D, M36I, R41K, R57K, Q61N, L63T, I64M, T96SF
 SM47SM47AF221051PINA  L10I, E35D, M36I, R57K, Q61N, L63T, I64L, T96SF
Gibb (2002)DMG6464_w26 NFV26D30N I15V, G16E, K20R, E35D, M36I, N37NT, R41K, R57K, L63T, E65D, I72TF
 DMG8686_w25 NFV8  L10V, I13V, I15V, G16E, K20KR, E35D, M36I, R41K, R57K, L63T, E65D, I72IATV, L89MF
Apetrei (2003)AC_Pat1RO.00.IS.01AY333462IDV, UnknownNAM46I, I54V, V82AL24I, K43TL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.01AY333463IDV, Unknown, SQV, NFVNAM46I, I54V, V82A, I84VL24I, K43T, G48W, F53LL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat2RO.00.IS.02AY333504IDV   I15V, G16E, Q18E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72TF
 AC_Pat4RO.00.IS.04AY333484IDV, SQV, NFV   L10V, T12S, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat5RO.00.IS.05AY333471IDV M46I, I54V, V82A L10I, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, T74S, L89MF
 AC_Pat6RO.00.IS.06AY333525IDV, RTV, NFV   I15V, L19I, E35D, M36I, R41K, R57K, I62V, L63T, E65D, V82I, L89M, I93LF
  RO.01.IS.06AY333526IDV, RTV, NFV, UnknownNA  L10V, I15V, L19I, K20T, E35D, M36I, R41K, R57K, I62V, L63T, E65D, V82I, L89M, I93L, F99YF
 AC_Pat7RO.00.IS.07AY333458IDV, SQV, NFV, UnknownNAM46L, I54V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.07AY333459IDV, SQV, NFV, UnknownNAM46L, I54V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat8RO.00.IS.08AY333522IDV, Unknown, SQV, NFVNA  T12S, I15V, Q18E, L19T, K20R, E35D, M36I, R41K, R57K, L63T, E65DF
  RO.01.IS.08AY333523IDV, Unknown, SQV, NFV, RTVNA  T12S, I15V, Q18E, L19T, K20R, E35D, M36I, R41K, R57K, L63T, E65DF
 AC_Pat20RO.00.IS.20AY333497IDV   I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.20AY333498IDV, RTV   I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat21RO.00.IS.21AY333455IDV   I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, L89MF
  RO.01.IS.21AY333456IDV   T12I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, L89MF
 AC_Pat22RO.00.IS.22AY333460IDV, RTV, NFV I54V, V82A L10V, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89MF
 AC_Pat23RO.00.IS.23AY333499IDV V82A I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.23AY333500IDV, SQV, NFV V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72T, L89MF
 AC_Pat24RO.00.IS.24AY333496IDV V82A L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, T74S, L89MF
 AC_Pat25RO.00.IS.25AY333502IDV   L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72TF
  RO.01.IS.25AY333503IDV G48V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72TF
 AC_Pat26RO.00.IS.26AY333486IDV   L10V, I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72V, T74S, L89MF
  RO.01.IS.26AY333487IDV, RTV M46I, I54V, V82T, I84V L10V, I15V, E35D, M36I, R41K, K55R, R57K, L63T, E65D, I72V, T74S, L89MF
 AC_Pat27RO.00.IS.27AY333516IDV   T12S, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63T, E65D, L89MF
  RO.01.IS.27AY333517IDV   T12S, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63T, E65D, L89MF
 AC_Pat28RO.00.IS.28AY333452IDV   I15V, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat29RO.00.IS.29AY333511IDV   T12S, I15V, G16E, K20R, E35D, M36I, R57K, L63T, E65D, I72T, L89MF
 AC_Pat30RO.00.IS.30AY333513IDV, RTV, SQV, NFV   T12S, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89M, Q92KF
 AC_Pat31RO.00.IS.31AY333518IDV   T12S, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, L89MF
  RO.01.IS.31AY333519IDV, SQV, NFV   T12S, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, L89MF
 AC_Pat32RO.00.IS.32AY333492IDV   L10I, I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M, I93LF
  RO.01.IS.32AY333493IDV, NFV   L10I, I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M, I93LF
 AC_Pat33RO.00.IS.33AY333477IDV   L10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72V, L89MF
  RO.01.IS.33AY333478IDV, NFV   L10V, I13V, I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72V, L89MF
 AC_Pat34RO.00.IS.34AY333521IDV   L10V, T12S, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89MF
 AC_Pat35RO.00.IS.35AY333491IDV   L10V, I15V, G16E, E35D, M36I, R41K, R57K, I62V, L63T, E65D, L89MF
 AC_Pat36RO.00.IS.36AY333461IDV, RTV, SQV, NFV M46L, I54V, V82A L10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, K70E, I72T, L89MF
 AC_Pat37RO.00.IS.37AY333488IDV, RTV L90M L10V, T12S, I15V, L19I, K20T, E35D, M36I, R41K, R57K, I62V, L63T, E65D, T74S, L89MF
 AC_Pat39RO.00.IS.39AY333501IDV   I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89MF
 AC_Pat40RO.00.IS.40AY333465IDV M46I, I54V, V82A L10V, I15V, G17E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat41RO.00.IS.41AY333507IDV   T12I, I15V, G16E, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat42RO.00.IS.42AY333520IDV25  L10V, T12S, I15V, L19V, K20R, E35D, M36I, R41K, R57K, I62V, L63T, L89M, I93LF
 AC_Pat43RO.00.IS.43AY333509IDV   T12N, I15V, G16E, K20R, E35D, M36I, R57K, I62V, L63T, E65D, I72T, L89MF
 AC_Pat44RO.00.IS.44AY333453IDV, RTV, SQV, NFV   I15V, K20R, L23V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, C95N, L97IF
 AC_Pat45RO.00.IS.45AY333473IDV I54V, V82A L10V, I15V, K20R, L23V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat46RO.00.IS.46AY333454IDV, Unknown, SQV, NFVNA  I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat47RO.00.IS.47AY333457IDV   T12S, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, V82I, L89MF
Monno (2003)ML_Pat12ML_Pat12 PINA  I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72IT, L89MF
Shafer (2003)A384_40794079bEF549325NFV30N88SL33LFL10I, I15V, K20KT, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, L89MF
Dumans (2004)RES40RES40AY390200NFV, RTV, Unknown>34  T12M, I15V, E35D, M36I, R57K, D60E, Q61D, L63T, G68E, H69R, I72TF
 RES093RES093AY390211IDV, RTV, Unknown>87I54V, V82AT, L90MF53LL10IV, K14R, I15V, G17D, L19I, K20R, E35D, M36I, R41K, D60E, Q61N, L63T, A71V, I72T, T74A, L89M, I93LF
Gomez-Carrillo (2004)9260892608AY365481PINAI54V, V82A, L90ML23I, F53LL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72TF
 9698496984AY365538PINAM46L, G48S, I54V, V82A, L90MF53LL10V, T12P, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, Q61D, L63T, E65D, A71V, I72T, I93LF
 9732297322AY365545PINAI54V, V82AL24I, K43T, F53LL10I, T12K, I15V, G16E, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72V, T74SF
 9735697356AY365546PINA  T12TP, I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63T, I72EF
 104145104145AY365694PINA  I15V, E35D, M36I, R41K, R57K, Q61D, L63T, E65D, I72T, I93LF
 109086109086AY365803PINAM46ML, I54V, V82A, L90M L10I, T12S, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, Q61N, I62V, L63T, A71V, I72T, T74S, I93LF
 109089109089AY365804PINAI54V, V82A, L90MK43T, F53LL10I, L19I, K20R, E35D, M36I, R41K, Q61N, L63T, E65D, C67E, A71V, I72T, T74S, V77I, I93IMF
 109481109481AY365818PINA  L10V, T12A, I15V, K20KR, M36I, R41K, R57K, Q61D, L63T, I93LF
 118790118790AY365958PINA  I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63T, I72TF
 119531119531AY365966PINAM46L, G48S, I54V, V82A, L90ML33LF, F53LL10V, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, Q61D, L63T, E65D, A71V, I72T, I93LF
 121584121584AY366001PINA  T12N, I15V, K20R, E35D, M36I, R41K, R57RK, D60DE, Q61DN, I62IV, L63T, I93LF
 122345122345AY366009PINAG48V, V82AF53LL10V, I15V, G16E, K20M, E35D, M36I, P39Q, R41K, K55R, R57K, Q61N, L63T, T74AF
Non-B Workgroup (2005)PL4965792049 LPV8  I15V, G17E, K20R, E35D, M36I, R57K, Q61H, L63T, I72T, L89MF
Rodrigues (2005)BR0181201AY643188RTV, NFV52M46MI, V82VA L10I, I15V, Q18L, K20KR, E35D, M36I, R41K, R57K, D60E, Q61N, L63T, C67X, H69Q, I72T, L89MF
 BLF_Pat29BR03SP247AY643171Unknown, NFV, SQV, RTV>88I54V, V82AN83DL10I, I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, I72T, L89M, I93LF
Weber (2005)F62040F62040AY677410NFV114  L10V, T12X, I15V, K20R, E35D, M36I, R41K, R57K, D60E, I62V, L63T, L89MF
Baxter (2006)48-11921192-30929DQ877270PINAM46I, I50IV, I54V, L76LV, V82AL33LF, Q58EL10IV, G16GE, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63T, E65D, I72T, L89MF
 48-10731073-30626DQ877335PINAI54A, V82F L10I, I13IV, L19V, K20R, E35D, M36I, N37H, R41K, K45T, F53C, K55T, Q61D, I62IV, L63T, I64M, A71V, I72T, V77I, I93LF
 48-11071107-30626DQ877397PINAI54V, V82A L10V, I15V, G16E, K20R, E35D, M36I, P39T, R41K, R57K, Q61N, L63TF
 48-11021102-30630DQ877407PINA  L10IV, I15V, Q18E, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72T, I93LF
 48-12711271-30923DQ877792PINAG48V, I54V, V82SL24I, L33F, Q58EL10I, I15V, G16E, K20R, E34Q, E35D, M36I, P39PT, R41K, R57K, I62V, L63T, E65D, I72T, L89MF
 48-26142614-30624DQ877904PINAM46L, I54V, V82AL33F, F53LL10V, T12I, I15V, G16E, L19V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, I85V, L89MF
 48-30433043-30305DQ877955PINAM46I, G48M, I54V, L76V, V82A, L90MK43T, F53LT4S, L10V, K14Q, I15V, G16E, L19I, K20R, E35D, M36V, P39S, K55R, R57K, Q61N, I62V, L63T, E65H, H69R, I72V, T74S, L89M, C95CSF
 48-61566156-30701DQ878732PINAI54V, V82A L10I, T12K, I15V, G16A, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72T, T74A, I93LF
 48-92509250-30908DQ877602PINAM46L, I54V, V82AV11VI, L24I, L33F, T74PL10I, I13V, G17E, L19I, K20R, E35D, M36I, R41K, R57K, Q61DN, I62V, L63T, E65D, I72T, L89MF
 48-90929092-30827DQ877655PINAM46I, I54V, V82A, L90MK43T, F53FLL10I, K20R, E35D, M36I, R41K, K55KR, R57K, Q61D, I62V, L63T, E65ED, I72T, T74TS, L89MF
Santos (2006)118118PRAY275778SQV, IDV, RTV, APV, LPV287G48V, I50V, I54S, V82AL33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37D, Q61N, L63T, I85V, L89MF
Dumans (2009)RENA162RENA162FJ405125SQV, NFV, IDV260  L10I, E35D, M36I, R41K, D60E, Q61N, I62V, L63T, C67D, T74S, V77I, L89MF
 RES153_02RES153_02FJ405160RTV, IDV39G48V, I54T, V82A, L90M L10I, T12P, I15V, G16E, K20R, E34A, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, A71V, I72T, T74S, I93LF
 RENA569RENA569FJ405166Unknown, NFV, RTV, IDV, APV>136  L10V, T12M, I15A, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, L89MF
 RENA446RENA446FJ405169RTV, NFV, Unknown, APV, SQV>205I54V, V82A, I84IV L10I, G17D, L19I, K20R, E35D, M36I, K55R, Q61D, L63T, E65D, I72T, T74S, L89MF
Aulicino (2011)ARM36WMRARM36WMRFJ525826PINAM46I, I47V, I54V, V82AL24I, K43T, F53LL10V, G16X, K20R, E35D, M36I, K55R, R57K, Q61N, L63T, H69R, T74S, L89MF
 ARM640RCAARM640RCAFJ525835PINAD30NN88DL10V, T12I, I15V, G16E, E35D, M36V, N37E, R41K, K45R, R57K, Q61N, L63T, I72T, V77I, I93LF
 ARO26PJARO26PJFJ525871PINAM46L, G48V, I54V, V82AQ58EL10I, K14R, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, Q61N, I62V, L63T, E65D, I72VF
 4389-M378SL4389-M378SLHQ158152PINAI54V T12N, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62IV, L63T, I66F, H69R, T74SF
 4532-M793GEM4532-M793GEMHQ158173PINA  L10I, I15V, E35D, M36I, R41K, R57K, D60E, Q61D, L63T, I72T, I93LF
 4352-O390RJL4352-O390RJLHQ158191PINA  K14S, I15V, K20R, E35D, M36I, R41K, D60E, Q61N, L63T, I72TF
Jones (2012)130439130439JN669490PINAM46I, I54V, V82A L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61E, L63T, E65D, I72T, I93LF
 137091137091JN669559PINAI54V, V82VA, L90M L10I, K20KR, E35D, M36I, R41K, Q61N, L63T, A71V, I72T, V77I, I93LF
 143429143429JN669640PINAL90LM K14KR, I15V, Q18E, K20T, E35D, M36I, R41K, R57K, Q61N, I62IV, L63T, I64IV, I72T, T74TS, I93LF
 145844145844JN669665PINAI54V, V82A, L90MF53L, Q58EL10I, I15V, G16E, K20R, E35D, M36V, R41K, K55R, R57K, Q61N, L63T, A71V, I72IATV, I93LF
 146046146046JN669668PINAM46L, I54L, V82A, L90ML33FL10I, T12EQ, I15V, G16E, K20R, E34V, E35D, M36I, P39S, R41K, K55R, R57K, Q61N, I62V, L63T, A71V, I72T, T74S, L89M, I93LF
 148547148547JN669716PINA  I15V, G16E, E35ED, M36I, P39PS, R41K, K43R, R57K, Q61N, L63T, E65D, I72ITF
 152726152726JN669785PINAV82VA L10IV, I15IV, E35D, M36I, P39S, R41K, R57K, Q61N, L63T, E65D, I72IT, I93LF
 152881152881JN669789PINA  L10I, T12K, I15V, E35ED, M36I, R41K, K43R, R57K, Q61N, L63T, I93LF
 154206154206JN669813PINAI54V, V82AS, L90LM L10I, T12S, I15V, K20R, E35D, M36I, R41K, Q61N, L63T, A71V, I72T, T74TS, I93ILF
 156236156236JN669856PINA  L10V, I15V, M36I, R41K, R57K, D60DE, Q61DN, L63T, E65D, I72T, I93LF
 156594156594JN669867PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K14R, Q18E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63T, E65D, A71V, L89M, I93LF
 157578157578JN669892PINAD30N, I54VN88DK14R, G17E, K20R, E35D, M36V, N37E, R41K, K43R, R57K, Q61N, L63T, E65D, H69Y, I72T, T74S, L89MF
 157709157709JN669896PINAM46I, I54V, L76V, V82AL33F, K43KTL10I, I15IV, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63T, H69Y, I72T, L89M, I93LF
 158859158859JN669936PINAV82A L10I, I15V, L19Q, K20R, E35D, M36I, R41K, K43KR, R57K, Q61N, I62V, L63T, E65D, I72T, T74AS, I93LF
 160414160414JN669976PINA  I15V, G17D, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72T, V82IF
 162487162487JN670039PINA  L10I, I15V, E35D, M36I, R41K, R57K, Q61DN, L63T, E65ED, C67CDGYF
 162844162844JN670049PINA  T12I, I15V, G16E, E35D, M36I, R41K, R57K, Q61D, L63T, E65D, I72VF
 165388165388JN670098PINA  E35D, M36I, R41RK, R57K, Q61N, L63T, E65D, I72TF
 167998167998JN670168PINAI47V, G48V, I54A, V82A L10I, G16E, K20R, E35D, M36I, N37NT, P39S, K43I, R57K, Q61N, I62V, L63T, H69Y, A71V, Q92K, I93LF
 168994168994JN670188PINA  L10V, I15V, L19Q, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, I72T, I93LF
 171337171337JN670256PINAM46I, I54V, L76V, V82A L10V, I15V, K20R, M36I, R41K, R57K, Q61N, L63T, E65D, I72T, L89M, I93LF
 171985171985JN670276PINA  L10I, T12E, I15V, M36I, R41K, D60E, Q61NS, L63T, I93LF
 173045173045JN670309PINAV82VA L10V, I15V, K20KR, M36I, R41K, R57K, Q61DN, L63T, E65D, I72T, I93LF
 175931175931JN670380PINAI54V, V82AQ58EL10V, T12N, I15V, G16GE, K20RS, E35D, M36I, N37T, R41K, R57K, Q61N, L63T, E65EDF
 176120176120JN670386PINA  I3L, W6WC, I15V, G17GE, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72T, I93LF
 179613179613JN670518PINAI54V, V82A, L90MF53LL10I, I15V, G16E, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63T, E65D, I72T, V77IF
 181761181761JN670585PINAM46I, I50V, I54V, L76V, V82T I3F, L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63T, C67W, A71V, I72T, I93LF
 183350183350JN670643PINA  L10I, K14R, I15V, G17E, K20R, M36I, R41K, R57K, Q61N, L63T, I72IT, I93LF
 184113184113JN670672PINA  L10V, T12P, K14R, E35D, M36I, R41K, R57K, Q61N, L63T, C67S, I72TF
 186960186960JN670725PINA  I13V, I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72TF
 187322187322JN670731PINAM46L, V82A I15V, G16E, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, L63T, E65D, I72T, T74SF
 187706187706JN670737PINA  I15V, Q18E, E35D, M36I, R41K, R57K, Q61N, L63T, V77I, I93LF
 189227189227JN670768PINAM46I, I47V, I54V, L76V, V82A L10V, T12TK, I15V, G16E, L19I, K20R, E35D, M36I, R41K, K45R, K55KR, R57K, Q61N, L63T, A71V, I72T, I93LF
 192040192040JN670842PINAD30N, L90ML33F, N88DL10V, T12I, I13V, I15V, E35D, M36IL, N37D, K43Q, R57K, Q61N, L63T, E65D, A71V, I72V, I93LF
 192746192746JN670864PINAV82A K20R, E35D, M36I, R41K, R57K, D60E, Q61D, L63T, E65D, I72T, Q92KF
 193188193188JN670887PINA  I15V, E35D, M36I, R41K, K43KR, R57K, Q61N, L63T, E65DF
 193358193358JN670894PINAL90M L10LI, T12N, I15V, K20M, E35D, M36I, R41K, R57K, D60E, Q61D, L63T, I72T, T74AF
 194537194537JN670939PINA  I15V, G17E, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, K70KR, I72VF
 195206195206JN670972PINA  L10I, T12K, I15V, M36I, R41K, K43R, R57K, Q61N, L63T, I93LF
 196067196067JN671012PINAV32I, M46MI, I54IL, I84V, L90MF53LL10I, T12N, I15V, L19I, K20R, E35D, M36I, N37NS, R41K, R57K, Q61D, L63T, I66IV, A71L, I72T, V77VI, I93LF
 196218196218JN671018PINAV82TQ58EQ2P, L10I, T12K, K14Q, I15V, K20R, E35D, M36I, R41K, D60E, Q61N, L63T, E65D, I72T, L89LP, I93LF
 196988196988JN671050PINA  I15V, G16E, E35D, M36I, R41K, K43KR, R57K, Q61N, L63T, E65DF
 198824198824JN671136PINA  L10V, T12AP, K14KR, I15V, G17E, K20KM, E35D, M36I, R41K, R57K, Q61N, L63T, A71T, I72T, I93LF
 199447199447JN671170PINAV82A L10I, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, I72T, T74S, I93LF
 200421200421JN671202PINA  L10I, I15V, G16E, E35D, M36I, N37ND, R57K, Q61D, L63T, E65D, I72T, I93LF
 201656201656JN671232PINA  L10I, K14KR, I15V, Q18E, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72IV, I93LF
 202293202293JN671265PINAM46L, I54V, V82AL24IL10I, I15V, K20R, E35D, M36I, N37E, R41K, R57K, Q61D, I62IV, L63T, T74TS, L89MF
 202616202616JN671281PINA  I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63T, I64M, I72T, V82VI, I93LF
 202725202725JN671289PINA  L10I, I15V, K20R, E21EK, E35Q, M36I, N37D, R41K, R57K, Q61D, L63T, I72T, I93LF
 203444203444JN671312PINA  I15V, K20R, M36I, N37D, R41K, R57K, Q61N, L63T, I93LF
 206165206165JN671393PINAM46L, I54V, I84VL24I, K43T, F53LL10I, I15V, G17D, K20T, E35N, M36I, K55R, Q61N, L63T, E65D, A71V, I72T, T74E, V82I, L89M, I93LF
Steegen (2014)12ZAKS33012ZAKS330KJ176609LPV   P39PS, R41K, R57K, L63T, H69K, I93LF