<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63Q
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 12
Isolates 12
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Brindeiro (2002)TVSP16TVSP16AY145813RTV84I54V, V82AQ58EL10V, T12N, I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63Q, E65DF
Dumans (2004)F136F136AY390083NFV, Unknown>108  T12Q, I15V, E35D, M36I, R41K, R57K, Q61D, L63Q, K70T, V82I, L89MF
Gomez-Carrillo (2004)107813107813AY365774PINA  I15V, E35D, M36I, R41K, R57K, D60E, Q61D, L63Q, K70R, I72TF
Baxter (2006)48-10551055-30707DQ877421PINAM46I, I47V, I54V, V82F, L90MF53FLL10I, K20I, E35D, M36V, R41K, R57K, Q61N, I62IV, L63Q, I64IV, A71V, T74S, I93LF
 48-12061206-30604DQ877750PINAM46L, I50V, I54V, V82AL24I, L33F, Q58EL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, H69Y, L89MF
Jones (2012)195597195597JN670987PINAL90M L10I, T12I, I13V, Q18H, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, L63Q, I64V, C67SF
 202905202905JN671293PINA  I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63Q, E65D, I72TF
Diaz (2015)RenG14829RenG14829KT745857PINAN88SL33I, Q58EL10I, T12E, I15V, E35N, M36I, P39Q, R41K, R57K, D60E, Q61D, L63Q, I85V, L89MF
 RenG14682RenG14682KT745710PINAM46I, I54V, V82AN88DL10V, I13V, I15V, G16E, K20I, E35N, M36I, R41K, K45R, K55KR, R57K, Q61N, L63Q, I64V, T74SF
 RenG14046RenG14046KT745074PINAI47V, G48A, I54A, V82AS L10I, I15V, G16GE, K20R, E35D, M36I, N37ND, R41K, K43KR, K45KR, R57K, Q61N, L63Q, A71V, I85V, L89I, Q92K, I93LF
 RenG13630RenG13630KT744658PINA  W6L, T12A, G16GE, L23LS, L24~, M36I, R41K, K45KR, R57K, Q61N, L63Q, I64V, I72ITF
 RenG12493RenG12493KT743521PINAM46L, I54V, V82A, I84VL24I, L33F, K43KTL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, I64L, E65D, A71L, I72T, T91S, I93LF