<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63I
Rx PI-naive
IncludeMixtures No
References 10
Patients 11
Isolates 11
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Tanuri (1999)BR97BR97AF079995None   Q2T, Q7L, I15V, K20R, E21G, E35D, M36I, R41K, R57K, Q61N, L63I, I72T, V82I, L89MF
Servais (2001)JS97287JS97287AJ012427None   L10I, T12N, I15V, K20M, E35D, M36I, P39Q, R41K, R57K, Q61N, L63I, I72T, L89M, I93LF
Machado (2004)N57N57AY569889None   T12K, I15V, L19I, E35D, M36I, N37D, R57K, D60E, Q61D, L63I, K70R, I72E, V82I, L89MF
von Wyl (2007)1095933841EF449776None   I13V, I15V, E35D, M36I, R41K, R57K, Q61N, I62V, L63I, I64M, I72V, L89MF
Cuevas (2009)P1467P1467.1EU822665None   L10V, G17E, K20R, E35N, M36I, N37D, R41K, R57K, Q61N, L63I, H69Y, I72TF
Vercauteren (2009)pt19831407969847GQ399041None   L10V, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63I, L89IMF
Ferreira (2010)p022Dip022GQ862327None   L10V, T12K, I15V, L19I, E35D, M36I, P39T, R41K, R57K, D60E, Q61D, L63I, L89MF
 p040Dip040GQ862334None   K14R, I15V, Q18E, K20R, E35D, M36I, R41K, Q61N, I62V, L63I, I72T, L89MF
Moussa (2010)1340-0837F7HM117937None   L10V, I13IV, I15V, G16A, K20R, E35D, M36I, N37D, K45R, R57K, D60E, Q61N, L63I, C67E, H69K, K70R, I72E, V82I, L89MF
Alencar (2013)RJ2-0015RJ2-0015JQ237944None   L10V, I13V, I15V, Q18E, K20R, E35D, M36I, R41K, R57K, Q61N, L63I, E65D, I72T, L89MF
Temereanca (2013)SR2SR2JX966496None   L10V, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63I, L89M, T91NF