<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63D
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 11
Isolates 11
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)103620103620AY365684PINAD30N, L90MN88DI13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63D, A71T, I72TF
 108926108926AY365800PINAM46I, I54V, V82A, L90M L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Y59S, Q61D, L63D, I72T, N83S, I93LF
Baxter (2006)48-10091009-30618DQ877323PINAG48GV, I54IV, V82VAFS L10I, K14R, I15V, K20KR, E35D, M36I, N37D, R41K, R57K, Q61N, L63D, E65D, I66IV, I72IV, I93LF
Aulicino (2011)ARN156RJEARN156RJEFJ525852PINAD30N, M46I, I54V, V82AL24I, L33F, N83D, N88DL10I, K20R, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63D, A71V, I72PT, T74SF
Jones (2012)191263191263JN670819PINA  L10V, T12I, I15V, E35D, M36I, N37D, R57K, Q61N, L63D, E65D, I72TF
 201335201335JN671219PINAI54V, V82T L10LV, T12I, I13V, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63D, I64V, H69Y, A71V, I72TF
Diaz (2015)RenG17085RenG17085KT748113PINAM46L, I47V, I54V, V82AL24I, L33F, F53L, Q58EL10I, G16A, K20R, E34EV, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63D, E65D, A71V, I72T, I93LF
 RenG14280RenG14280KT745308PINAI54V, L90ML23I, F53LL10I, K20I, E35N, M36V, R41K, K55KR, R57K, D60E, Q61N, I62IV, L63D, I64IV, E65ED, I66IF, K70R, A71V, I72T, L89M, Q92QK, I93ILF
 RenG11340RenG11340KT742368PINAD30NN88DL10V, I13V, I15V, K20R, E35D, M36I, R57K, Q61N, L63DF
 RenG10262RenG10262KT741290PINA  T4S, L5F, L10IV, T12EK, I15V, G16E, E35D, M36I, P39S, R41K, R57K, D60E, Q61N, L63D, I72TF
 RenG10845RenG10845KT741873PINAD30N, M46IL23I, L33I, F53L, N88DR8RQ, L10I, I15IV, K20T, E35N, M36I, N37NS, R41K, K45Q, R57K, D60E, Q61N, L63D, I66V, A71T, V77VI, I93LF