<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63C
Rx PI-naive
IncludeMixtures No
References 22
Patients 35
Isolates 35
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Balotta (2001)CB-1292CB-1292AF295282None   L10V, K14R, I15V, E35D, R41K, R57K, Q61N, L63CF
Kijak (2001)ARG12ARG12PRAF328572None   T12Q, K14R, I15V, Q18L, E35D, M36I, R41K, R57K, Q61N, L63C, I93LF
 ARG29ARG29PRAF328587None   I15V, E35D, M36I, R41K, R57K, Q61N, L63C, I93VF
 ARG33ARG33PRAF328591None   I15V, E35D, M36I, R41K, Q61N, L63C, I93LF
Brindeiro (2003)BRSP364BRSP364AY213196None   K14R, Q18L, E35D, M36I, R41K, R57K, Q61N, L63C, I72T, V77I, L89M, I93LF
 BRP2095BRP2095AY213356None   L10I, E35D, M36I, R41K, R57K, Q61N, L63CF
Soares (2003)BRP2052BRP2052AF527254None   T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63C, E65D, C95SF
Espinosa (2004)3636AY140129None   I15V, K20R, M36I, R41K, R57K, Q61N, L63C, I72T, I93LF
 5050AY140144None   L10V, T12A, K14R, I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63C, I72TF
Machado (2004)cs159cs159AY569830None   L10I, I15V, G17E, L19I, N37S, R57K, Q61N, L63C, E65D, I93LF
Rodrigues (2005)BLF_Pat36BR02SP117AY643135None   L10V, T12I, I15V, G16E, E35D, M36I, P39PQ, R41K, R57K, D60E, Q61N, L63C, I72T, L89MF
de Sa Filho (2006)BREPM11948BREPM11948DQ085871None   L10I, E35D, M36I, R41K, R57K, Q61N, L63C, C67D, T74S, V77I, L89MF
Petroni (2006)AP_ARRP006AP_ARRP006DQ206649None   I15V, E35D, M36I, R41K, R57K, Q61N, L63C, T74SF
 AP_ARRP044AP_ARRP044DQ345497None   L10I, T12K, K14R, I15V, G17E, M36I, R41K, R57K, Q61N, L63C, C67S, K70R, I93LF
Rodrigues (2006)BR04RS143BR04RS143DQ070592None   I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63C, E65DF
Dilernia (2007)F004F004EF120076None   I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63CF
 F076F076EF120123None   I15V, L19I, E35D, M36I, N37D, R41K, R57K, L63CF
 F177F177EF120159None   T12S, I15V, E35D, M36I, R41K, R57K, Q61N, L63C, H69YF
 N31N31EF120290None   L10I, I15V, E35D, M36I, R41K, R57K, Q61N, L63C, K70KE, I93LF
Eyer-Silva (2007)BRSQ0505BRSQ05EF042629None   I15V, E35D, M36I, R41K, R57K, Q61N, L63C, V77I, V82I, L89M, I93LF
 BRSQ4405BRSQ44EF042650None   I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, E65D, I72TF
 BRSQ6905BRSQ69EF042667None   K14R, I15V, L19I, E35D, M36I, R41K, R57K, Q61N, L63C, V77I, V82I, L89M, I93LF
Gonsalez (2007)79HIV_79GU288768None   I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, L63C, I72T, L89MF
Ndembi (2008)CMYD-6604CMYD-66DQ990430None   L10I, I15V, K20R, E35D, M36I, R41K, L63C, E65D, H69Q, L89MF
Aghokeng (2009)CYN418CYN418GU191589None   L10V, I13IV, I15IV, K20R, E35D, M36I, R41K, I62V, L63C, L89MF
de Sa-Filho (2009)5538155381IthGQ294600None   I15V, Q18L, K20R, M36I, R41K, R57K, Q61N, L63CF
 5554655546PgrGQ294608None   T12I, I13V, I15V, G17E, K20R, M36I, R41K, R57K, Q61N, L63C, L89MF
Vercauteren (2009)pt11716161314874GQ399853None   L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63C, V77IF
 pt6659017941016GQ400359None   L10V, I13V, I15V, G16GE, Q18QE, E35D, M36MI, R41K, R57K, Q61N, L63C, I72V, V77I, L89MF
Aulicino (2011)3247-F3753247-F375HQ158222None   I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63C, H69Y, I72TF
Gaspareto (2012)ECDB9ECDB9PTHM752153None   T12A, I15V, E35D, M36I, R41K, R57K, Q61D, L63C, I72EF
Alencar (2013)SP2-0037SP2-0037JQ238071None   T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63CF
 RJ2-0096RJ2-0096JQ238182None   E35D, M36I, R41K, R57K, Q61N, L63C, K70M, I72RF
Ferreira (2013)BR09SP191BR09SP191HM534109None   I3V, L10I, K14R, I15V, G17E, E35D, M36I, R41K, R57K, Q61N, L63C, I72V, V77VI, I93LF
Frentz (2013)EHR-12336EHR-12336JX299738None   I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63C, I93LF