<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63C
Rx PI-naive
IncludeMixtures No
References 21
Patients 27
Isolates 27
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Brindeiro (2003)BRSP364BRSP364AY213196None   K14R, Q18L, E35D, M36I, R41K, R57K, Q61N, L63C, I72T, V77I, L89M, I93LF
Soares (2003)BRP2052BRP2052AF527254None   T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63C, E65D, C95S, F99LF
Rodrigues (2005)BLF_Pat36BR02SP117AY643135None   L10V, T12I, I15V, G16E, E35D, M36I, P39PQ, R41K, R57K, D60E, Q61N, L63C, I72T, L89MF
de Sa Filho (2006)BREPM11948BREPM11948DQ085871None   L10I, E35D, M36I, R41K, R57K, Q61N, L63C, C67D, T74S, V77I, L89MF
Petroni (2006)AP_ARRP006AP_ARRP006DQ206649None   I15V, E35D, M36I, R41K, R57K, Q61N, L63C, T74SF
 AP_ARRP044AP_ARRP044DQ345497None   L10I, T12K, K14R, I15V, G17E, M36I, R41K, R57K, Q61N, L63C, C67S, K70R, I93LF
Dilernia (2007)F004F004EF120076None   I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63CF
Eyer-Silva (2007)BRSQ6905BRSQ69EF042667None   K14R, I15V, L19I, E35D, M36I, R41K, R57K, Q61N, L63C, V77I, V82I, L89M, I93LF
Gonsalez (2007)79HIV_79GU288768None   I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, L63C, I72T, L89MF
Ndembi (2008)CMYD-6604CMYD-66DQ990430None   L10I, I15V, K20R, E35D, M36I, R41K, L63C, E65D, H69Q, L89MF
Aghokeng (2009)CYN418CYN418GU191589None   L10V, I13IV, I15IV, K20R, E35D, M36I, R41K, I62V, L63C, L89MF
de Sa-Filho (2009)5538155381IthGQ294600None   I15V, Q18L, K20R, M36I, R41K, R57K, Q61N, L63CF
 5554655546PgrGQ294608None   T12I, I13V, I15V, G17E, K20R, M36I, R41K, R57K, Q61N, L63C, L89MF
Vercauteren (2009)pt6659017941016GQ400359None   L10V, I13V, I15V, G16GE, Q18QE, E35D, M36MI, R41K, R57K, Q61N, L63C, I72V, V77I, L89MF
Gaspareto (2012)ECDB9ECDB9PTHM752153None   T12A, I15V, E35D, M36I, R41K, R57K, Q61D, L63C, I72EF
Melo (2012)0341RI0341RIJF804808None   L10V, T12P, I15V, G16E, E35D, M36T, N37E, R41K, R57K, Q61N, L63C, I72TF
Ferreira (2013)BR09SP191BR09SP191HM534109None   I3V, L10I, K14R, I15V, G17E, E35D, M36I, R41K, R57K, Q61N, L63C, I72V, V77VI, I93LF
Velasco-de-Castro (2014)05BRRJLTS14205BRRJLTS142KF922009None   I15V, L19I, E35D, M36I, R41K, R57K, Q61N, L63C, L89MF
Dauwe (2015)F_03018F_03018KT863842None   L10V, I15V, E35D, M36I, R41K, R57K, L63C, H69Y, L89MF
 F_06033F_06033KT863845None   L10V, I15V, E35D, M36I, R41K, R57K, L63C, H69Y, L89MF
Guimaraes (2015)BRSP786-14BRSP786-14KP115567None   E35D, R41K, R57K, Q61N, L63C, I64M, H69Y, V77I, L89M, I93LF
 BRSP451-13BRSP451-13KP115453None   T12N, I15V, G16E, L19I, E35D, M36I, P39Q, R41K, K45R, R57K, Q61N, L63CF
Lam (2016)20720212072021KR867789None   K14R, G17E, E35D, M36I, R41K, R57K, Q61N, L63C, E65DF
Lima (2016)08PE08008PE080KX020985None   L10V, T12I, I15V, G16E, E35D, M36I, R41K, K45R, R57K, Q61N, L63C, I72T, I93LF
 08PE04908PE049KX020979None   L10I, T12I, I13V, I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63C, I72TF
 02PE02902PE029KX020990None   T12I, I13V, I15V, G16E, E35D, M36L, P39T, R41K, R57K, Q61N, L63C, L89MF
Pessoa (2016)10BR_SP06810BR_SP068KT427795None   L10V, T12M, I13V, I15V, E35D, M36I, N37D, R41K, R57K, Q61N, L63CF