<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63A
Rx PI-naive
IncludeMixtures No
References 26
Patients 37
Isolates 37
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Op de Coul (2000)CE97R101CE97R101AF204040None   K14R, I15V, E35D, M36I, R41K, R57K, L63A, E65D, L89MF
Kijak (2001)ARG-43ARG-43AF329586None   T12A, I15V, M36I, N37D, R41K, R57K, Q61N, L63AF
Brindeiro (2003)BRRJ921BRRJ921AY213277None   T12S, I15V, E35D, M36I, R41K, R57K, D60E, Q61D, L63A, H69Y, I72T, C95SF
Shafer (2003)A384_40794079aEF549324None   L10I, I15V, E35D, M36I, R41K, R57K, Q61N, L63A, L89MF
Soares (2003)BRRJ820BRRJ820AF527326None   K14R, I15V, M36I, R41K, K45R, R57K, Q61N, L63A, C67D, I72T, V77I, C95SF
Petroni (2006)AP_ARRP028AP_ARRP028DQ206661None   L10I, I15V, G17D, E35D, M36I, R41K, R57K, Q61N, L63A, K70KR, I93LF
Santos (2006)RG173RG173DQ344021None   G17E, E35D, M36I, R41K, R57K, Q61N, L63A, H69Y, L89MF
Vidal (2006)NV_KBS15402.KBS154AM041021None   I15V, E35D, M36I, R41K, R57K, I62V, L63A, H69Y, L89MF
 NV_KTB18302.KTB183AM040990None   T12D, L19K, K20R, L23P, D29H, E35D, M36I, R41K, L63A, L89MF
Dilernia (2007)F174F174EF120156None   I15V, E35D, M36I, R41K, R57K, Q61N, L63A, V77LF
 F207F207EF120173None   I15V, Q18E, E35D, M36I, R41K, R57K, Q61N, L63AF
Eyer-Silva (2007)BRSAP09_PED05BRSAP09PDQ899707None   L10V, K20R, M36I, N37E, R57K, Q61N, L63A, I72MF
Gonsalez (2007)30HIV_30GU288731None   T12S, E35D, M36I, R41K, R57K, D60E, Q61N, L63A, I64IM, V77I, L89MF
Paraschiv (2007)49834983_2004JQ083004None   L10I, T12I, I13V, I15V, E35D, M36I, R41K, R57K, I62V, L63A, L89MF
Varella (2007)5ini5ini None   K14R, I15V, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, C67D, I72T, V77IF
 32ini32ini None   T12Q, I15V, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, H69Y, V77I, L89MF
Ndembi (2008)CMYD-6404CMYD-64DQ990428None   L10V, I15V, K20R, M36I, R41K, I62V, L63A, I72T, L89MF
Cardoso (2009)BRGO3133BRGO3133FJ594169None   E35D, M36I, R41K, K43R, R57K, Q61D, L63A, E65D, L89MF
Cuevas (2009)X2592_1X2592_1GU326146None   E35D, M36I, R41K, R57K, Q61N, L63A, L89M, I93LF
 X2657_1X2657_1GU326163None   E35D, M36I, R41K, R57K, Q61N, L63A, L89M, I93LF
Hawkins (2009)Q242ZZQ242FJ931229None   L10I, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69Q, L89M, I93LF
Koyalta (2009)28TCHAD-28FJ688182None   L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63A, T74S, L89MF
Vercauteren (2009)pt11206481167628GQ399904None   I13V, K14R, G17E, E35D, M36I, R41K, R57K, Q61N, L63A, E65D, L89MF
 pt8388126543316GQ400186None   T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63A, E65D, V77I, L89MF
 pt7908428524942GQ400234None   T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63A, E65D, V77I, L89MF
Yebra (2010)39896307SP398963FJ481683None   K14R, I15IV, E35D, M36I, N37D, L63A, I64VF
Graf (2011)SC37SC37JF774004None   I13V, I15V, G17E, L19I, K20M, E35D, M36I, R57K, Q61N, L63A, I64M, I93LF
Santos (2011)J78J78_PRJN010456None   G17E, E35D, M36I, R41K, R57K, Q61N, L63A, H69Y, I72T, V77I, L89MF
Alencar (2013)RJ2-0036RJ2-0036JQ237958None   E35D, M36I, P39PS, R41K, R57K, Q61N, I62V, L63A, L89MF
 RJ2-0075RJ2-0075JQ238121None   L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63A, I93LF
 PE2-0063PE2-0063JQ238150None   K14R, E35D, M36I, R41K, Q61N, L63A, L89MF
Frentz (2013)EHR-00383EHR-00383JX299541None   L10V, I15V, G16GE, G17GE, K20R, E35D, M36I, R41K, I62V, L63A, H69Q, L89MF
 EHR-38978EHR-38978JX300203None   T12N, I15V, E35D, M36I, R41K, R57K, Q61N, L63A, E65D, V77I, L89M, Q92KF
Temereanca (2013)SR1SR1JX966486None   L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63A, E65D, L89M, T91AF
 SR41SR41JX966517None   I15V, E35D, M36I, R41K, R57K, L63A, E65D, L89M, I93LF
 SR112SR112 None   T12P, I15V, E35D, M36I, R41K, R57K, L63A, E65D, L89M, I93DF
Meixenberger (2014)07-0069907-00699KJ770503None   L10V, I15V, G16GE, G17GE, K20R, E35D, M36I, R41K, I62V, L63A, H69Q, L89MF