<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L63A
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 43
Isolates 43
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Belec (2000)r31r31_m12AF204352IDV52G48V L10V, I15V, Q18E, E35D, M36I, R41K, K43R, R57K, I62V, L63AF
Rodrigues (2005)BLF_Pat1BR03SP230AY643170IDV, Unknown>47  T12A, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63A, L89MF
 BLF_Pat25BR02SP184AY643140NFV113L90M L10V, I15V, K20R, E35D, M36I, P39Q, R41K, R57K, Q61N, I62V, L63A, T74S, L89MF
Waleria-Aleixo (2008)RES222RES222FJ591939PINAL90M L10V, I15V, L19I, K20T, E35D, M36I, R41K, R57K, Q61N, L63A, T74S, I93LF
 RES211RES211FJ591934PINAV32I, V82A, L90M L10LI, I15V, K20R, E35D, M36I, N37ND, R41K, K43R, R57K, Q61N, I62V, L63A, A71V, I85V, Q92KF
 08PR06065608PR060656FJ591511PINAL90LM K14R, I15V, Q18M, E35D, M36I, R41K, R57K, Q61N, L63A, V82I, T96TNF
 08RJ05042608RJ050426FJ591644PINAV82A K20R, M36I, R41K, R57K, Q61N, L63AF
 RG4RG4FJ592023PINA  T12A, E35D, M36I, R41K, K43R, R57K, Q61N, L63A, I72VF
Dumans (2009)RENA578RENA578FJ405042IDV, SQV, RTV, NFV, LPV335M46I, I54A, V82AL24I, L33F, Q58EL10I, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63A, L89MF
 RES222_03RES222_03FJ405162NFV, Unknown>165L90M L10V, I15V, L19I, K20T, E35D, M36I, R41K, R57K, Q61N, L63A, T74S, I93LF
Jones (2012)158844158844JN669935PINAM46I, I47V, I54V, V82SL23I, K43T, F53LL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63A, A71V, I72V, T74S, L89M, I93LF
 165415165415JN670100PINA  I15V, E35D, M36I, R41K, I62V, L63A, E65D, T74TS, L89MF
 172418172418JN670288PINA  T12N, N37S, R57K, Q61N, L63A, I72TF
 175482175482JN670360PINA  P9PS, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63A, E65D, I72VF
 178684178684JN670487PINA  T12N, I15V, L19I, M36I, R41K, K43R, R57K, D60E, Q61D, L63AF
 205418205418JN671361PINAD30N K20T, E35DN, M36I, N37D, K45Q, R57K, D60E, Q61DN, L63A, A71V, I93IL, F99FSF
Diaz (2015)RenG17266RenG17266KT748294PINAM46MFIL, I54V, V82AL10FK20R, E34EG, E35D, M36I, N37ND, R41K, R57K, Q61N, L63A, H69CY, I72EV, L89MF
 RenG16044RenG16044KT747072PINA  K14Q, I15V, E35D, M36I, R41K, R57K, Q61N, L63A, E65DF
 RenG16704RenG16704KT747732PINAM46L, V82A L10I, T12D, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63A, E65D, L89MF
 RenG17487RenG17487KT748515PINAI54V, V82A, L90ML33FL10I, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, L63A, I64M, C67S, T74S, L89M, I93LF
 RenG15778RenG15778KT746806PINA  L10V, G17E, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63A, E65DF
 RenG16204RenG16204KT747232PINAM46I, I54V, L76V, V82A L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63A, T74S, L89MF
 RenG15758RenG15758KT746786PINA  T12M, I15V, L19S, E35D, M36I, R41K, R57K, Q61N, L63A, E65DF
 RenG16849RenG16849KT747877PINAM46IF53L, N88TL10V, I15IV, G16E, L19I, K20T, E35D, M36V, N37T, P39T, R41I, K45Q, R57K, D60DE, Q61N, I62V, L63A, E65D, V77I, L89MF
 RenG16201RenG16201KT747229PINAM46L, I54V, V82A, L90ML33F, F53L, T74TPSL10IV, G16GA, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, Q61N, I62IV, L63A, I64M, A71V, Q92KF
 RenG15395RenG15395KT746423PINAM46MI, L90M I13V, E35D, M36I, R41K, R57K, D60E, Q61N, I62IV, L63A, I72T, L89IMF
 RenG15046RenG15046KT746074PINA  I15V, G16E, K20R, E34EK, E35D, M36I, N37ND, P39T, R41K, R57K, D60E, Q61D, I62V, L63A, I93LF
 RenG14071RenG14071KT745099PINA  T12A, K14R, I15V, E35D, M36I, R41K, R57K, D60E, Q61D, L63A, L89MF
 RenG15368RenG15368KT746396PINAV32I, I47V, I50LL33F, G73SL10I, T12N, I15V, L19I, E35D, M36I, N37E, R57K, Q61N, I62V, L63A, I66L, Q92HF
 RenG13786RenG13786KT744814PINA  T12A, I13V, I15IV, G17R, E35D, M36I, R41K, R57K, D60E, Q61D, L63A, V77VI, L89MF
 RenG13651RenG13651KT744679PINA  E35D, M36I, R41K, K43R, R57K, Q61N, L63A, I64LF
 RenG14443RenG14443KT745471PINAV32I I13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63A, A71V, L89TF
 RenG12128RenG12128KT743156PINAM46MIL, I50L, V82AL33LF, Q58EL10I, K20R, E35D, M36I, R41K, K55R, Q61N, L63A, C67DF
 RenG13001RenG13001KT744029PINA  T12K, I15V, L19I, E35ED, M36I, R41K, Q61N, L63A, E65D, L89MF
 RenG12957RenG12957KT743985PINA  T12TI, K14KR, I15V, G16GE, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63A, L89M, Q92KF
 RenG12247RenG12247KT743275PINAI54V, V82AF53LL10V, I15V, G16E, K20R, E35D, M36I, P39T, R41K, K45Q, K55R, R57K, Q61N, L63A, L89MF
 RenG12683RenG12683KT743711PINAI54V, V82TL24IL10I, T12TK, I13V, K20I, E35D, M36I, R41K, R57K, Q61N, L63A, T74S, L89IF
 RenG11940RenG11940KT742968PINA  T12TS, K14R, I15V, E35D, M36I, R41K, Q61N, L63A, L89LM, I93LF
 RenG11642RenG11642KT742670PINA  G16E, K20M, E35D, M36I, R57K, Q61N, L63A, I72TF
 RenG10607RenG10607KT741635PINA  I15S, G16R, G17E, K20R, E35D, M36I, K43I, R57K, Q61N, L63A, L89MF
 RenG11135RenG11135KT742163PINAM46MI, I54V, L90M I13IV, K14KR, I15V, K20T, E35D, M36I, P39V, R41K, R57K, Q61N, I62V, L63A, I72V, T74S, L89I, Q92KF
 RenG10948RenG10948KT741976PINA  K14KR, L19LP, K20KM, E35D, M36I, R41K, R57K, Q61N, L63AF
 RenG10550RenG10550KT741578PINAD30NL33LI, Q58EI13V, K20T, E35D, M36I, N37T, R41K, K45R, R57K, Q61N, L63A, I64IM, A71IV, V77VI, L89T, I93LF

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