<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I54S
Rx >= 1 PI
IncludeMixtures No
References 3
Patients 6
Isolates 6
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Baxter (2006)48-90259025-30825DQ877501PINAM46I, I54S, V82AL33FL10I, I13V, I15V, K20M, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, T74S, L89IF
Santos (2006)118118PRAY275778SQV, IDV, RTV, APV, LPV287G48V, I50V, I54S, V82AL33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37D, Q61N, L63T, I85V, L89MF
Diaz (2015)RenG15534RenG15534KT746562PINAG48V, I54S, V82AK43TL10I, I15V, K20R, E35D, M36I, N37NS, R41RK, R57K, Q61N, I62V, A71V, I72T, T74S, L89I, I93LF
 RenG15101RenG15101KT746129PINAM46I, I54S, V82A, L90ML33I, K43TL10I, K14T, I15V, L19V, K20R, E35D, M36I, N37D, K55R, Q61N, T74S, I85V, L89IF
 RenG15039RenG15039KT746067PINAM46I, G48S, I54S, V82ML24I, K43TL10V, L19IV, K20R, E35D, M36I, R41K, F53Y, K55Q, R57K, D60DN, Q61DN, I62V, L63T, I64V, E65D, I72T, T74AF
 RenG11817RenG11817KT742845PINAG48V, I54S, V82ACGSV11I, L33LF, T74PSL10I, T12K, I13V, K14R, I15V, K20T, E35N, M36I, R41P, R57K, Q61N, L89IF