<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I54M
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 8
Isolates 8
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)110390110390AY365836PINAI54ML33F, Q58EL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I85VF
 113771113771AY365884PINAI47V, I54M, L90M L10I, I13IV, I15V, K20I, E35DN, M36I, R41K, R57K, Q61N, L63P, T74S, V82VI, I85VF
Baxter (2006)48-11801180-30922DQ877428PINAV32I, M46I, I47V, I54M, L90MF53LL10I, I15V, K20I, E35N, M36I, R41K, R57K, Q61N, L63P, I72IV, T74S, V82I, I85V, L89LIF
 48-93499349-30923DQ877289PINAV32I, M46I, I47V, G48M, I54M, V82AL33F, F53LL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, T74S, L89IF
Aulicino (2011)ARN567GMARN567GMFJ525862PINAI54M, V82M, L90MV11I, L33F, K43T, G73S, L89VL10I, I13V, K14R, I15V, G17E, K20T, E35N, M36I, R41K, R57K, Q61N, L63P, T74S, I93LF
Jones (2012)166335166335JN670126PINAI54M, I84VL33FI15V, E34D, E35D, M36I, R41K, R57K, Q61N, V82IF
 167774167774JN670161PINAV32I, I47V, I54M, N88S, L90LML33F, G73S, L89VT12I, I13V, I15V, G16E, K20R, E35ED, M36I, R41K, R57K, Q61N, G68GE, A71IV, I72T, V77VEF
 194491194491JN670938PINAI54M, V82A, L90MG73SL10V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, A71V, I72T, Q92KF