<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I54L
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 20
Isolates 20
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Baxter (2006)48-92789278-30924DQ877616PINAM46I, I47V, I54L, V82A, L90MK43T, F53L, G73C, L89VL10V, I15V, G16E, Q18H, K20M, E34Q, M36I, P39S, K55R, D60E, I62V, L63P, I85VF
Waleria-Aleixo (2008)08PR05030708PR050307FJ591335PINAD30N, I54LN88DI13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63H, A71IV, I72IV, Q92RF
Jones (2012)188212188212JN670748PINAI54LL33FI15V, G16E, K20Q, E34A, E35D, M36I, P39S, R41K, R57K, D60E, Q61N, I62V, I72TF
Diaz (2015)RenG17021RenG17021KT748049PINAV32I, I47V, I50V, I54L, V82ML33F, K43T, T74PL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37S, R57K, Q61N, L63T, E65D, I72V, L89FF
 RenG17260RenG17260KT748288PINAM46MI, I54LL33F, G73GS, N88GT12KN, I15V, K20T, E35D, M36I, N37E, K45K*, R57K, Q61N, I62V, L63P, A71V, I85VF
 RenG15848RenG15848KT746876PINAI54L, N88SK43KTL10V, T12TK, K14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61N, L63T, I64V, V77I, L89M, I93LF
 RenG14415RenG14415KT745443PINAM46ML, I54L, L90ML23LI, F53LL10IV, I15V, G16E, K20T, E35D, M36V, P39PS, R41K, R57K, Q61N, L63T, A71AV, I72T, T74S, I85V, L89IM, I93LF
 RenG14584RenG14584KT745612PINAI54L, V82A, L90MV11I, L33F, K43T, F53L, G73SI13V, I15V, G16GCW, L19V, K20R, E21G, L24F, E35D, M36I, N37T, R41K, K55R, R57K, D60E, Q61H, I62V, L63P, A71V, I72FF
 RenG14459RenG14459KT745487PINAI54L, L90LML23I, Q58EL10I, I15V, K20T, E35D, M36I, N37E, P39S, R57K, I62V, L63P, H69Q, A71V, I93LF
 RenG14011RenG14011KT745039PINAI54L, L76V, V82FL33F, Q58EL10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, P39T, R41K, R57K, Q61N, A71V, I72R, V77I, L89IM, I93LF
 RenG11912RenG11912KT742940PINAI54L, I84V, L90ML33F, G73GCL10V, I13V, Q18H, L19I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, I72V, V77IF
 RenG12314RenG12314KT743342PINAD30N, I54LL33F, Q58QE, N88DR8P, L10V, I13V, I15V, K20T, T31A, E35D, M36I, K43R, R57K, Q61N, L63C, T74S, L89IMF
 RenG12245RenG12245KT743273PINAV32I, M46I, I47V, I54LF53LL10I, I15V, K20T, E35D, M36I, P39T, R57K, D60E, Q61D, I62V, L63E, A71T, I72T, L89MF
 RenG12374RenG12374KT743402PINAV32I, M46I, I54L, I84V, L90ML33F, L89VL10V, L19I, K20R, E35D, M36I, N37D, R41K, K55N, R57K, Q61N, A71V, Q92KF
 RenG12253RenG12253KT743281PINAV32I, I54LK43T, F53L, L89VL10V, I13V, K20R, E34D, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, A71VF
 RenG11600RenG11600KT742628PINAM46I, I54L, V82A, I84VL24I, L33FL10I, I13V, I15V, K20R, E35D, M36I, R41K, K43I, R57K, Q61N, I62V, I72T, I85V, L89M, T91SF
 RenG11539RenG11539KT742567PINAV32I, M46I, I47V, I54L, V82AL10FI, L33LF, N83DI13V, G16A, K20R, A22V, E35D, M36I, R41K, R57K, Q61N, I64V, A71V, T74S, T91S, I93LF
 RenG11018RenG11018KT742046PINAI54L, N88S L10V, I13V, K20R, E34A, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, A71T, I72TF
 RenG11397RenG11397KT742425PINAM46I, I47V, I54L, V82AL33I, K43T, N83DK20KR, A22V, E35D, M36I, N37D, R57K, D60E, Q61E, I72T, L89IF
 RenG10072RenG10072KT741100PINAV32I, I54L L10V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, I64V, A71V, I85IV, L89MF