<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I54L
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 19
Isolates 19
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)104712104712AY365711PINAI54L T12K, I15V, L19I, K20T, E35D, M36I, R41K, R57K, Q61N, L63LV, I72T, T74SF
 123281123281AY366020PINAI54L I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, I64V, I72R, T74A, V75I, I93LF
Aulicino (2011)ARM896DNGARM896DNGFJ525845PINAM46I, I54L, L76V, V82AL24I, K43TL10I, T12P, I15V, G16E, L19P, K20R, E35D, M36I, N37D, K55R, R57K, Q61D, A71V, I72R, I93LF
Jones (2012)146046146046JN669668PINAM46L, I54L, V82A, L90ML33FL10I, T12EQ, I15V, G16E, K20R, E34V, E35D, M36I, P39S, R41K, K55R, R57K, Q61N, I62V, L63T, A71V, I72T, T74S, L89M, I93LF
 167151167151JN670145PINAI54L, L90M L10V, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63C, E65D, I72T, V77I, I93LF
 169723169723JN670207PINAI54L, L90ML33F, Q58EL10LI, I15V, L19LI, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I72IM, V75IF
 179961179961JN670533PINAI54L, L90M I15V, G16GE, K20T, E35D, M36I, R41K, R57K, Q61N, I62IV, L63C, T74S, I93LF
 188212188212JN670748PINAI54LL33FI15V, G16E, K20Q, E34A, E35D, M36I, P39S, R41K, R57K, D60E, Q61N, I62V, I72TF
 192094192094JN670846PINAI54L, N88S L10V, T12R, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, T74S, V77I, I93LF
Diaz (2015)RenG15848RenG15848KT746876PINAI54L, N88SK43KTL10V, T12TK, K14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61N, L63T, I64V, V77I, L89M, I93LF
 RenG14415RenG14415KT745443PINAM46ML, I54L, L90ML23LI, F53LL10IV, I15V, G16E, K20T, E35D, M36V, P39PS, R41K, R57K, Q61N, L63T, A71AV, I72T, T74S, I85V, L89IM, I93LF
 RenG14011RenG14011KT745039PINAI54L, L76V, V82FL33F, Q58EL10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, P39T, R41K, R57K, Q61N, A71V, I72R, V77I, L89IM, I93LF
 RenG12314RenG12314KT743342PINAD30N, I54LL33F, Q58QE, N88DR8P, L10V, I13V, I15V, K20T, T31A, E35D, M36I, K43R, R57K, Q61N, L63C, T74S, L89IMF
 RenG12671RenG12671KT743699PINAI54L, L90ML23I, F53L, L89VL10V, T12K, I13V, I15V, K20T, E35D, M36I, N37E, R41K, R57K, Q61N, L63P, H69HQ, A71I, T74S, Q92R, I93LF
 RenG12245RenG12245KT743273PINAV32I, M46I, I47V, I54LF53LL10I, I15V, K20T, E35D, M36I, P39T, R57K, D60E, Q61D, I62V, L63E, A71T, I72T, L89MF
 RenG12374RenG12374KT743402PINAV32I, M46I, I54L, I84V, L90ML33F, L89VL10V, L19I, K20R, E35D, M36I, N37D, R41K, K55N, R57K, Q61N, A71V, Q92KF
 RenG12253RenG12253KT743281PINAV32I, I54LK43T, F53L, L89VL10V, I13V, K20R, E34D, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, A71VF
 RenG11600RenG11600KT742628PINAM46I, I54L, V82A, I84VL24I, L33FL10I, I13V, I15V, K20R, E35D, M36I, R41K, K43I, R57K, Q61N, I62V, I72T, I85V, L89M, T91SF
 RenG11018RenG11018KT742046PINAI54L, N88S L10V, I13V, K20R, E34A, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, A71T, I72TF