<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I54A
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 20
Isolates 20
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ceccherini-Silberstein (2004)1794-930A1794-930AAY855361PINAG48V, I54A, V82AK43TL10I, T12V, I15V, G16E, K20R, E35D, M36I, N37H, P39S, R41K, R57K, Q61N, I62V, I72T, L89I, I93LF
Rodrigues (2005)BLF_Pat8BR03SP01AY643156Unknown, RTV, IDV>51M46L, I54A, V82AL24I, K43TL10I, I15V, L19I, K20R, E35D, M36I, K55R, R57K, Q61N, L63P, A71V, I85V, L89IF
Baxter (2006)48-91109110-30917DQ877697PINAI54A, V82A L10I, T12TN, I15V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, I62V, L63C, A71V, T74S, L89LI, I93LF
Dumans (2009)RENA578RENA578FJ405042IDV, SQV, RTV, NFV, LPV335M46I, I54A, V82AL24I, L33F, Q58EL10I, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63A, L89MF
 75PR75PRFJ405164NFV104G48V, I54A, V82TK43TL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, L63E, E65D, I72V, L89M, I93LF
Jones (2012)151726151726JN669766PINAI54A, I84V, L90MV11I, G73GDNS, L89VL10I, T12TP, I13V, G17E, K20V, E35D, M36I, N37NDEK, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
 167998167998JN670168PINAI47V, G48V, I54A, V82A L10I, G16E, K20R, E35D, M36I, N37NT, P39S, K43I, R57K, Q61N, I62V, L63T, H69Y, A71V, Q92K, I93LF
 193645193645JN670907PINAI54A, V82AL24I, K43TL10I, T12N, L19I, K20R, E34K, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, L63P, I66F, A71VF
 202350202350JN671269PINAM46L, I54A, V82AL89VL10I, T12I, I13V, I15V, G16A, L19P, K20L, E35D, M36I, N37ND, R41RK, K45KR, K55KR, R57K, Q61D, A71V, I72TF
Diaz (2015)RenG16151RenG16151KT747179PINAV32I, M46I, I47V, I54A, V82AL76ML10I, I15V, L19I, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, I62IV, L63V, I64L, A71I, I72T, L89M, I93LF
 RenG13615RenG13615KT744643PINAG48A, I54A, V82AL24I, L33LI, K43ITL10I, K20R, E35D, M36I, N37D, R41RK, R57K, Q61N, L63P, L89LMF
 RenG14639RenG14639KT745667PINAM46IL, G48A, I54A, V82AL24I, L33F, Q58EL10I, I13V, K20M, E35N, M36I, N37ND, F53FY, R57K, Q61N, I62IV, L63LP, L89M, Q92QKF
 RenG14046RenG14046KT745074PINAI47V, G48A, I54A, V82AS L10I, I15V, G16GE, K20R, E35D, M36I, N37ND, R41K, K43KR, K45KR, R57K, Q61N, L63Q, A71V, I85V, L89I, Q92K, I93LF
 RenG13058RenG13058KT744086PINAM46I, I54A, V82M, L90ML33F, T74PL10I, I13V, K14R, I15V, K20R, E35D, M36I, N37DE, R41K, R57K, Q61N, L63T, I64V, H69S, L89MF
 RenG13137RenG13137KT744165PINAM46I, I54A, V82A, L90ML33IL10I, T12P, I15V, L19P, K20V, E35N, M36I, R41K, R57K, Q61N, I62V, K70E, A71V, T74S, G86GA, L89I, T91S, I93LF
 RenG11995RenG11995KT743023PINAV32I, M46I, I47V, I54A, V82A L10I, T12A, I15V, L19P, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, I64V, A71V, Q92KF
 RenG11433RenG11433KT742461PINAI54A, V82A, L90M L10I, I13V, K14R, I15IV, K20R, E35D, M36I, N37D, R41K, K55KR, R57K, Q61N, I62V, L63P, A71V, I72T, T74S, L89I, Q92KF
 RenG11226RenG11226KT742254PINAV32I, I54A, V82AL24I, K43TL10I, K20R, L33*, E34K, E35D, M36I, R41K, R57K, Q61N, L63V, I64V, T74SF
 RenG10567RenG10567KT741595PINAI54A, V82A L10I, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, L63S, I64IL, A71V, I72IT, I93LF
 RenG11532RenG11532KT742560PINAG48A, I54A, V82A W6W*, L10V, T12I, I13V, I15V, G16E, K20R, E35D, M36V, N37K, R41K, R57K, Q61N, L63T, I72T, T74S, L89MF