<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I54A
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 29
Isolates 29
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)9297792977AY365483PINAI54A, V82A L10I, T12P, I15V, K20R, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, L63P, A71V, I85V, I93LF
 9386893868AY365492PINAI54A, V82F Q7QH, L10I, T12TP, I15V, K20R, E35D, M36I, R41K, K45T, K55T, D60E, Q61D, I64V, A71V, I72T, I93LF
 9714997149AY365542PINAI54A, V82F, L90M Q7QH, L10I, T12TP, K20R, E35D, M36I, R41K, K43KN, R57K, Q61N, L63V, I64V, A71V, I72T, T74S, I93LF
 105677105677AY365732PINAI54A, V82A L10I, I15V, K20R, E35D, M36I, N37D, R41K, F53I, R57K, D60E, Q61D, I62V, L63C, I66IL, A71V, I93LF
Rodrigues (2005)BLF_Pat8BR03SP01AY643156Unknown, RTV, IDV>51M46L, I54A, V82AL24I, K43TL10I, I15V, L19I, K20R, E35D, M36I, K55R, R57K, Q61N, L63P, A71V, I85V, L89IF
Baxter (2006)48-10731073-30626DQ877335PINAI54A, V82F L10I, I13IV, L19V, K20R, E35D, M36I, N37H, R41K, K45T, F53C, K55T, Q61D, I62IV, L63T, I64M, A71V, I72T, V77I, I93LF
 48-91109110-30917DQ877697PINAI54A, V82A L10I, T12TN, I15V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, I62V, L63C, A71V, T74S, L89LI, I93LF
Dumans (2009)RENA578RENA578FJ405042IDV, SQV, RTV, NFV, LPV335M46I, I54A, V82AL24I, L33F, Q58EL10I, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63A, L89MF
 75PR75PRFJ405164NFV104G48V, I54A, V82TK43TL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, L63E, E65D, I72V, L89M, I93LF
Jones (2012)151726151726JN669766PINAI54A, I84V, L90MV11I, G73GDNS, L89VL10I, T12TP, I13V, G17E, K20V, E35D, M36I, N37NDEK, R41K, R57K, Q61N, L63P, A71I, I72R, V82I, Q92KF
 167998167998JN670168PINAI47V, G48V, I54A, V82A L10I, G16E, K20R, E35D, M36I, N37NT, P39S, K43I, R57K, Q61N, I62V, L63T, H69Y, A71V, Q92K, I93LF
 172771172771JN670300PINAI54A, I84V L10I, I13V, I15V, L19I, K20R, E34N, E35D, M36I, R41K, R57K, Q61N, L63P, A71T, I72T, I93LF
 177288177288JN670432PINAM46I, I50V, I54A, V82A, L90ML33F, Q58E, L89VL10I, I13V, I15V, G16Q, K20R, E35N, M36I, P39Q, R41K, K55R, R57K, Q61N, L63P, A71V, I93ILF
 179773179773JN670525PINAM46I, I54A, V82A, L90MT74PL10I, I15V, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, I62V, L63V, A71V, L89M, I93LF
 183614183614JN670654PINAM46L, G48A, I54A, V82AK43TL10V, T12K, I15V, L19I, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, E65D, I72TF
 202350202350JN671269PINAM46L, I54A, V82AL89VL10I, T12I, I13V, I15V, G16A, L19P, K20L, E35D, M36I, N37ND, R41RK, K45KR, K55KR, R57K, Q61D, A71V, I72TF
 207271207271JN671428PINAM46L, I54A, V82A L10V, K14KR, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, A71V, I72T, I93LF
Diaz (2015)RenG16151RenG16151KT747179PINAV32I, M46I, I47V, I54A, V82AL76ML10I, I15V, L19I, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, I62IV, L63V, I64L, A71I, I72T, L89M, I93LF
 RenG16629RenG16629KT747657PINAM46L, I54A, V82AL24I, L33F, K43KT, N83NDL10IV, I13V, G16E, K20R, E35DN, M36I, N37DE, R41K, K55KR, R57K, Q61N, L63NT, I64IL, A71IV, I72T, I93LF
 RenG13615RenG13615KT744643PINAG48A, I54A, V82AL24I, L33LI, K43ITL10I, K20R, E35D, M36I, N37D, R41RK, R57K, Q61N, L63P, L89LMF
 RenG14046RenG14046KT745074PINAI47V, G48A, I54A, V82AS L10I, I15V, G16GE, K20R, E35D, M36I, N37ND, R41K, K43KR, K45KR, R57K, Q61N, L63Q, A71V, I85V, L89I, Q92K, I93LF
 RenG13058RenG13058KT744086PINAM46I, I54A, V82M, L90ML33F, T74PL10I, I13V, K14R, I15V, K20R, E35D, M36I, N37DE, R41K, R57K, Q61N, L63T, I64V, H69S, L89MF
 RenG13137RenG13137KT744165PINAM46I, I54A, V82A, L90ML33IL10I, T12P, I15V, L19P, K20V, E35N, M36I, R41K, R57K, Q61N, I62V, K70E, A71V, T74S, G86GA, L89I, T91S, I93LF
 RenG11995RenG11995KT743023PINAV32I, M46I, I47V, I54A, V82A L10I, T12A, I15V, L19P, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, I64V, A71V, Q92KF
 RenG12449RenG12449KT743477PINAM46I, I54A, V82L, L90MQ58EL10I, K14R, I15V, G16Q, K20T, E35N, M36V, N37S, P39S, R41K, F53FY, R57K, D60E, Q61N, L63T, C67E, H69Y, A71V, I72T, V77I, I93LF
 RenG11433RenG11433KT742461PINAI54A, V82A, L90M L10I, I13V, K14R, I15IV, K20R, E35D, M36I, N37D, R41K, K55KR, R57K, Q61N, I62V, L63P, A71V, I72T, T74S, L89I, Q92KF
 RenG11226RenG11226KT742254PINAV32I, I54A, V82AL24I, K43TL10I, K20R, L33*, E34K, E35D, M36I, R41K, R57K, Q61N, L63V, I64V, T74SF
 RenG10567RenG10567KT741595PINAI54A, V82A L10I, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, L63S, I64IL, A71V, I72IT, I93LF
 RenG11532RenG11532KT742560PINAG48A, I54A, V82A W6W*, L10V, T12I, I13V, I15V, G16E, K20R, E35D, M36V, N37K, R41K, R57K, Q61N, L63T, I72T, T74S, L89MF