<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation F53L
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 157
Isolates 158
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Apetrei (2003)AC_Pat1RO.01.IS.01AY333463IDV, Unknown, SQV, NFVNAM46I, I54V, V82A, I84VL24I, K43T, G48W, F53LL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
Dumans (2004)RES093RES093AY390211IDV, RTV, Unknown>87I54V, V82AT, L90MF53LL10IV, K14R, I15V, G17D, L19I, K20R, E35D, M36I, R41K, D60E, Q61N, L63T, A71V, I72T, T74A, L89M, I93LF
 RES077RES077AY390203SQV192L90MF53LL10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, T74S, L89MF
Gomez-Carrillo (2004)9260892608AY365481PINAI54V, V82A, L90ML23I, F53LL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72TF
 9698496984AY365538PINAM46L, G48S, I54V, V82A, L90MF53LL10V, T12P, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, Q61D, L63T, E65D, A71V, I72T, I93LF
 9732297322AY365545PINAI54V, V82AL24I, K43T, F53LL10I, T12K, I15V, G16E, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72V, T74SF
 9824098240AY365571PINAM46I, I54V, V82AL24I, L33LF, K43T, F53L, N83DL10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, A71V, I93ILF
 104136104136AY365692PINAI54V, V82T, L90MF53L, G73SI15V, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, H69Y, A71VF
 105358105358AY365725PINAI54V, V82AF53LL10V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, A71V, T74A, I93LF
 107166107166AY365763PINAI54V, V82A, L90MF53LL10V, K14KR, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, T74S, I93LF
 109089109089AY365804PINAI54V, V82A, L90MK43T, F53LL10I, L19I, K20R, E35D, M36I, R41K, Q61N, L63T, E65D, C67E, A71V, I72T, T74S, V77I, I93IMF
 114725114725AY365912PINAI54V, L90MF53L, G73SL10I, I15V, K20R, E35D, M36I, N37S, R41K, R57K, Q61N, L63P, A71V, I72TF
 119531119531AY365966PINAM46L, G48S, I54V, V82A, L90ML33LF, F53LL10V, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, Q61D, L63T, E65D, A71V, I72T, I93LF
 120763120763AY365988PINAG48A, I54V, V82AL24I, F53LL10I, T12S, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, T74S, L89MF
 122345122345AY366009PINAG48V, V82AF53LL10V, I15V, G16E, K20M, E35D, M36I, P39Q, R41K, K55R, R57K, Q61N, L63T, T74AF
 122494122494AY366012PINAM46I, I54V, V82AL24I, F53LL10I, I15V, G16E, K20R, E35D, M36I, R41K, K43I, K55R, R57K, Q61N, L63C, L89LMF
 122744122744AY366015PINAM46I, I50V, I54V, V82AF53L, L76ML10I, I15V, K20R, E35D, M36I, R41K, K45R, K55R, R57K, Q61N, L63S, E65D, K70T, A71V, I72E, L89M, I93LF
 123822123822AY366027PINAI54V, V82A, L90MF53LL10IMV, I15V, G16GA, K20R, E35D, M36I, R41K, K55R, R57K, D60DE, Q61DN, L63P, A71V, I72TF
 124260124260AY366031PINAI54V, V82VF, I84IVF53LL10V, K20R, E35D, M36I, R41K, K43KR, K45KEIV, R57K, Q61N, I64V, A71T, I93ILF
 126743126743AY366057PINAV32I, M46I, I47V, I54V, V82AL24I, L33F, F53LL10V, I15V, K20R, E34V, E35D, M36I, R41K, Q61N, I62V, L63P, T74S, L89M, Q92KF
Non-B Workgroup (2005)PL882265161 SQV, IDV, LPV270G48M, I54V, V82AL24I, F53LL10I, T12I, I15V, G17E, K20M, E35D, M36IV, N37K, L38M, K43R, R57K, Q61N, L63PF
Rodrigues (2005)BLF_Pat23BR03SP224AY643169Unknown, RTV, APV>4M46MI, I50V, I54V, V82A, L90ML23I, F53L, L76ML10I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, I64M, L89M, I93LF
Baxter (2006)48-10071007-30609DQ877312PINAM46I, I47V, I54V, V82A, L90MF53LL10V, L19LI, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, I62V, L63LP, A71V, I85V, I93LF
 48-10631063-30612DQ877316PINAV32I, M46I, I54IV, V82A, L90ML33F, F53L, G73GS, N83DL10I, I13V, I15V, K20R, M36I, R41K, Q61N, L63P, A71V, I72TF
 48-10161016-30617DQ877322PINAM46I, I54V, V82AL24I, F53LL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, H69Y, A71V, I93LF
 48-10191019-30619DQ877325PINAG48V, I54V, V82AF53LL10I, I15V, K20R, E35D, M36I, R41K, Q61N, I62IV, L63S, I64L, I72T, T74S, L89M, I93LF
 48-11961196-30924DQ877381PINAI54V, V82A, L90MF53LL10I, K20R, E35D, M36I, N37ND, R41K, D60E, Q61N, L63P, H69R, A71V, I85VF
 48-10391039-30619DQ877394PINAI54V, V82T, L90MF53L, G73SI15V, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, H69Y, A71V, T74TS, I85IVF
 48-10271027-30707DQ877408PINAV32I, M46I, I47V, I54V, V82AL24I, L33F, F53LL10V, I15V, K20R, E34V, E35D, M36I, R41K, Q61N, I62V, L63P, T74S, L89M, Q92KF
  1027-31124DQ877409PI, RTV, TPV>20M46MI, I47IV, I54V, V82A, L90ML33LF, F53LL10IV, I15V, K20R, E34EV, E35D, M36I, N37NS, R41K, D60DE, Q61DN, I62V, L63P, A71AV, T74S, L89LM, Q92QKF
 48-11801180-30922DQ877428PINAV32I, M46I, I47V, I54M, L90MF53LL10I, I15V, K20I, E35N, M36I, R41K, R57K, Q61N, L63P, I72IV, T74S, V82I, I85V, L89LIF
 48-12451245-30414DQ877768PINAM46I, I54V, V82T, L90MF53L, G73SL10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, I62V, L63P, H69HY, A71IV, I72T, I93LF
 48-22512251-30925DQ877885PINAG48M, I54V, V82AL24I, F53L, G73GCFVL10I, T12I, I15V, G17E, K20M, E35D, M36I, K43R, R57K, Q61N, I62IV, L63P, T91TSF
 48-26142614-30624DQ877904PINAM46L, I54V, V82AL33F, F53LL10V, T12I, I15V, G16E, L19V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, I85V, L89MF
 48-30433043-30305DQ877955PINAM46I, G48M, I54V, L76V, V82A, L90MK43T, F53LT4S, L10V, K14Q, I15V, G16E, L19I, K20R, E35D, M36V, P39S, K55R, R57K, Q61N, I62V, L63T, E65H, H69R, I72V, T74S, L89M, C95CSF
 48-42864286-30910DQ878509PINAI54AV, V82F, L90ML33F, K43T, F53LL10IV, G16E, L19I, K20R, E35D, M36I, N37T, P39T, R41K, D60E, Q61E, I62V, L63P, I64V, H69Q, A71V, I93LF
 48-60236023-30403DQ878622PINAG48M, I54V, V82AL24I, K43KT, F53LL10I, I15V, Q18E, K20R, E35D, M36I, N37NK, R41K, R57K, Q61N, E65D, T74S, L89MF
 48-93499349-30923DQ877289PINAV32I, M46I, I47V, G48M, I54M, V82AL33F, F53LL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, T74S, L89IF
 48-91869186-30901DQ877291PINAM46L, I54V, V82AL24I, L33F, K43T, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I64L, A71V, I72T, L89I, I93LF
 48-91499149-30826DQ877714PINAM46L, I54V, V82AL24I, L33F, K43T, F53LR8P, L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, K70R, L89LM, Q92KF
Dumans (2009)RENA133RENA133FJ405126IDV, SQV, NFV, RTV274I54V, V82A, L90MF53LL10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P, A71VF
 RENA555RENA555FJ405127SQV, NFV, RTV, IDV, Unknown>191I54V, V82A, L90ML33F, K43T, F53L, T74PL10V, I13V, K14R, G16E, K20R, E35D, M36I, P39T, R41K, R57K, D60E, Q61N, I62V, L63H, A71I, I72V, I93LF
 RES314_03RES314_03FJ405155SQV226L90MF53LL10V, I15V, Q18E, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, L89MF
Aulicino (2011)ARM36WMRARM36WMRFJ525826PINAM46I, I47V, I54V, V82AL24I, K43T, F53LL10V, G16X, K20R, E35D, M36I, K55R, R57K, Q61N, L63T, H69R, T74S, L89MF
 ARM730WDARM730WDFJ525838PINAI54V, V82AL24I, F53L, Q58E, N83DL10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, A71VF
 ARN311BMSARN311BMSFJ525857PINAM46L, G48Q, I54V, L76V, V82A, L90MV32L, F53L, Q58EL10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, A71V, T74S, V77I, I93LF
Jones (2012)128155128155JN669449PINAI54V, V82A, L90MF53LL10V, I15V, G16E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63A, A71V, I93LF
 130542130542JN669493PINAI54V, V82A, I84VF53LT4TS, L10V, T12E, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, A71V, T74S, I85V, L89IF
 143027143027JN669634PINAG48A, I54V, V82AL24I, F53LL10I, T12S, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, T74S, L89MF
 145844145844JN669665PINAI54V, V82A, L90MF53L, Q58EL10I, I15V, G16E, K20R, E35D, M36V, R41K, K55R, R57K, Q61N, L63T, A71V, I72IATV, I93LF
 148707148707JN669719PINAI54V, V82A, L90ML33I, F53L, G73S, L89VL10I, I13V, K20R, E35D, M36I, K43E, K55R, R57K, D60K, Q61N, I62V, L63P, A71I, I72E, C95LF
 153756153756JN669805PINAM46L, G48GEQR, I54V, V82AL24I, F53LL10I, I15V, G17E, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71AVF
 158844158844JN669935PINAM46I, I47V, I54V, V82SL23I, K43T, F53LL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63A, A71V, I72V, T74S, L89M, I93LF
 159501159501JN669954PINAI54V, V82A, L90MK43T, F53LL10I, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71L, T74S, I93LF
 161363161363JN670004PINAI54V, V82A, L90MF53L, T74PL10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, A71V, I93L, C95FF
 164492164492JN670077PINAM46L, I54V, V82AL24I, L33LF, K43KT, F53L, G73SL10V, K14R, I15V, L19LI, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, A71VF
 171070171070JN670244PINAI54V, V82A, L90MV11VI, L33I, F53L, G73S, L89LVL10IV, I13V, K20R, E35D, M36I, R41RK, K43KE, K55R, R57K, D60EK, Q61N, I62IV, L63P, A71IV, I72EV, C95LF
 177354177354JN670436PINAG48MV, I54V, V82A, L90MF53LL10I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63LP, G68E, A71V, I93LF
 177430177430JN670439PINA F53LL10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61S, A71V, I72RF
 178718178718JN670488PINAM46L, I54V, V82AL24I, F53LL10V, I15V, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63P, C67EF
 179613179613JN670518PINAI54V, V82A, L90MF53LL10I, I15V, G16E, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63T, E65D, I72T, V77IF
 180359180359JN670545PINAI54V, V82T, L90MF53LL10I, I15V, L19LI, K20R, L24F, E35D, M36I, N37E, R41K, K55R, R57K, Q61N, L63P, A71I, T74S, Q92KF
 183504183504JN670649PINAM46I, I54V, V82A, L90ML33F, K43KT, F53L, T74PL10V, I15V, K20M, E35N, M36L, N37ND, L38W, R41K, K55R, R57K, Q61N, I62V, L63P, H69R, A71V, I72V, I93LF
 190134190134JN670789PINAI54V, V82SL24I, F53LL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, A71VF
 196067196067JN671012PINAV32I, M46MI, I54IL, I84V, L90MF53LL10I, T12N, I15V, L19I, K20R, E35D, M36I, N37NS, R41K, R57K, Q61D, L63T, I66IV, A71L, I72T, V77VI, I93LF
 196870196870JN671042PINAV32I, M46I, I47V, I54V, V82A, L90LMF53L, G73CL10I, I15V, G16A, K20R, E35D, M36I, N37ND, R41K, K55R, R57K, Q61N, L63P, A71AV, V77VI, I93ILF
 197011197011JN671053PINAI54V, L90MF53L, G73SI15V, L19V, E35D, M36I, R41K, R57K, D60E, Q61N, L63P, A71VF
 198351198351JN671114PINAM46I, I47V, I54V, V82SF53LL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63Q, I64L, A71V, I93LF
 198678198678JN671129PINAM46L, G48Q, I54V, V82AL24I, F53LL10I, I15V, G17E, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61D, I62V, L63PF
 206165206165JN671393PINAM46L, I54V, I84VL24I, K43T, F53LL10I, I15V, G17D, K20T, E35N, M36I, K55R, Q61N, L63T, E65D, A71V, I72T, T74E, V82I, L89M, I93LF
 207306207306JN671430PINAM46L, I54V, V82AL24I, G48E, F53L, L89VL10I, I13IV, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, I64L, H69Y, A71V, Q92K, I93LF
Grossman (2014)2727 LPV, SQV257G48M, I54V, V82AL24I, L33F, F53LL10I, I15V, Q18E, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, I72V, V75IF
Diaz (2015)RenG17206RenG17206KT748234PINAM46I, I47V, I54V, V82A, L90ML33F, F53L, Q58EL10I, I13V, Q18IL, L19V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I66F, A71T, I72IM, L89I, Q92KF
 RenG17085RenG17085KT748113PINAM46L, I47V, I54V, V82AL24I, L33F, F53L, Q58EL10I, G16A, K20R, E34EV, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63D, E65D, A71V, I72T, I93LF
 RenG16988RenG16988KT748016PINAM46I, I50L, V82CFLR, L90MF53LL10I, I13L, K20I, E34Q, E35D, M36I, N37T, R41K, K55KN, R57K, Q61N, L63C, I64L, A71V, I72T, T74S, L89M, I93LF
 RenG17077RenG17077KT748105PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41PQ, R57K, Q61N, I62V, L63P, A71I, V77I, L89TF
 RenG16096RenG16096KT747124PINAM46L, I54V, V82AL24I, K43T, F53LL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, T74S, L89MF
 RenG15931RenG15931KT746959PINAM46I, I47V, I54V, V82AK43T, F53LL10I, T12E, L19I, K20R, E35D, M36I, N37T, R41K, K55R, R57K, Q61N, I62V, L63T, I66F, I72V, T74S, V77VI, L89I, T91S, Q92K, F99FLF
 RenG15682RenG15682KT746710PINAI47IV, I50IV, I54V, V82C, L90MM46MV, F53L, L76ML10IV, I15V, G16Q, L19I, K20KR, E35D, M36I, N37ND, P39Q, R41K, K45R, K55R, R57K, Q61DN, L63T, E65D, C67DE, L89MF
 RenG16827RenG16827KT747855PINAI54V, V82F, I84VF53LL10V, I15V, G16E, K20T, E35D, M36I, P39Q, R41K, K45V, R57K, D60E, Q61D, I72R, T74A, V77I, L89MF
 RenG17232RenG17232KT748260PINAM46I, I47V, I50V, L76V, V82AV11I, L33F, F53LL10V, I13V, I15V, Q18L, L19Q, K20R, E34KNRS, E35D, M36I, N37D, R41K, R57K, Q61N, I66F, A71V, L89I, T91AF
 RenG16414RenG16414KT747442PINAL90ML23I, F53LL10V, K14R, I15V, K20T, E35D, M36I, N37ST, R41K, R57K, Q61D, I62IV, L63P, A71AV, I72IL, T74S, V77I, I93LF
 RenG16208RenG16208KT747236PINAD30N, L90MF53L, N88DI15V, K20T, E35D, M36I, N37E, R41K, R57K, Q61N, L63P, I66T, A71AV, Q92QRF
 RenG17309RenG17309KT748337PINAM46I, I50V, V82A, L90ML33F, K43T, F53LL10V, G16E, K20R, E34N, E35D, M36I, P39S, R41K, K55R, R57K, D60E, Q61D, L63HP, A71I, V77I, L89M, I93LF
 RenG16106RenG16106KT747134PINAL90MF53LL10V, I13IV, I15V, K20R, E35D, M36I, N37NT, R41K, R57K, D60E, Q61D, L63P, A71IVF
 RenG17332RenG17332KT748360PINAV32I, M46L, I47V, V82FF53LL10I, K20R, E35D, M36I, N37S, R41K, R57K, Q61N, L63T, E65D, A71I, I72T, V77I, I85V, I93LF
 RenG16345RenG16345KT747373PINAG48V, I54V, V82AL24I, F53LL10I, G16GE, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63PT, E65D, I72IT, L89MF
 RenG15949RenG15949KT746977PINAG48A, I54V, L76V, V82A, L90MF53LL10I, I15V, G16GA, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63T, A71V, I72T, T74S, L89M, I93LF
 RenG16832RenG16832KT747860PINAG48ML23I, F53LL10I, T12R, I15V, G16E, L19IV, K20T, E35D, M36I, P39Q, R41K, Q61N, I62IV, L63T, E65D, I72T, T74A, V75I, I93LF
 RenG16322RenG16322KT747350PINAI50L, L90ML33F, F53L, T74APL10V, T12TA, I13IV, I15S, G16R, K20R, E34N, E35D, M36I, P39T, R41K, K55KR, R57K, Q61N, L63T, A71AITV, I72T, V77VI, L89MF
 RenG16180RenG16180KT747208PINA F53L, G73SL10V, I13V, I15V, K20T, E35D, M36I, N37T, R41K, K55HN, R57K, Q61N, L63P, A71T, T74S, V77I, Q92KF
 RenG17240RenG17240KT748268PINAV32I, M46I, I47V, I54M, L90ML33F, F53L, L89VL10I, I13V, I15V, L19V, K20R, E35D, M36I, N37DE, R41K, G51A, R57K, Q61N, I66F, A71V, G73N, V77I, V82IF
 RenG16849RenG16849KT747877PINAM46IF53L, N88TL10V, I15IV, G16E, L19I, K20T, E35D, M36V, N37T, P39T, R41I, K45Q, R57K, D60DE, Q61N, I62V, L63A, E65D, V77I, L89MF
 RenG16201RenG16201KT747229PINAM46L, I54V, V82A, L90ML33F, F53L, T74TPSL10IV, G16GA, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, Q61N, I62IV, L63A, I64M, A71V, Q92KF
 RenG17315RenG17315KT748343PINAM46I, I50L, V82A, N88NSL33F, F53LL10V, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, H69Y, A71V, I72T, T74S, L89TF
 RenG15740RenG15740KT746768PINAM46I, V82AV32A, L33F, F53LL10I, I13V, G16E, K20R, E35D, M36L, R41K, Q61N, L63T, I66F, I72T, T74A, L89MF
 RenG14507RenG14507KT745535PINAM46I, I47V, I54V, V82AF53L, Q58EL10V, K14R, G17E, L19V, K20R, E35D, M36I, N37D, R41RK, K55R, R57K, Q61N, L63T, E65D, I72T, V77I, L89MF
 RenG14257RenG14257KT745285PINAG48EQ, L90MF53L, T74PST4S, L10V, I15V, G16Q, K20T, E35D, M36I, N37NADT, P39S, R41K, R57RK, D60E, Q61N, L63P, A71V, V77I, I93LF
 RenG14903RenG14903KT745931PINAM46I, I47V, I54V, V82AF53LL10I, I15V, G16E, K20M, E35D, M36V, R57K, Q61N, E65D, A71V, I72T, I93LF
 RenG14713RenG14713KT745741PINAI54V, L90ML23IV, F53LL10V, K20R, E35D, M36I, N37T, R41K, R57K, D60E, Q61D, I62V, I64V, A71AV, I72R, V77I, L89M, I93L, C95CFF
 RenG14526RenG14526KT745554PINAD30N, M46I, I47V, I54V, V82A, L90ML33F, F53L, Q58E, N88DL10V, T12K, I15V, G16Q, K20T, E35S, M36I, P39S, R41K, K45R, R57K, D60E, Q61D, L63P, A71I, L89IF
 RenG14597RenG14597KT745625PINAM46L, I54V, V82AL33I, K43T, F53L, N83DL10I, I13V, K20R, A22V, E35D, M36I, R41K, K55R, R57RK, Q61N, A71T, I72T, T74AS, L89I, T91SF
 RenG14530RenG14530KT745558PINAI50L, V82AL33F, F53LL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, D60E, Q61DN, T74TA, V77I, L89MF
 RenG13828RenG13828KT744856PINAM46I, I47V, I54V, V82T, I84VL33F, K43T, F53L, T74PL10I, I13IV, K20R, E35D, M36I, N37ND, R41K, D60DE, Q61N, I62IV, L63P, A71V, Q92QRF
 RenG14104RenG14104KT745132PINAG48M, V82S, I84VL24I, L33F, K43T, F53LL10V, I15IV, G16A, L19LV, K20R, E35D, M36I, N37K, R41K, R57K, D60E, Q61N, I62V, L63P, T74S, L89MF
 RenG14383RenG14383KT745411PINAI54V, L90ML33I, F53L, N83DL10I, I13V, A22V, E34EAKT, E35D, M36I, N37D, R41K, D60E, Q61N, I62V, A71T, L89IF
 RenG14415RenG14415KT745443PINAM46ML, I54L, L90ML23LI, F53LL10IV, I15V, G16E, K20T, E35D, M36V, P39PS, R41K, R57K, Q61N, L63T, A71AV, I72T, T74S, I85V, L89IM, I93LF
 RenG13602RenG13602KT744630PINAI50L, V82A, L90ML33F, F53LL10V, I13V, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, I62V, G68E, H69HY, A71V, I72T, L89IF
 RenG14157RenG14157KT745185PINAM46L, G48T, I54V, L76V, V82AF53LI15V, G16E, L19I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, E65D, A71V, I72T, I93LF
 RenG14761RenG14761KT745789PINAD30N, G48V, I54V, V82AL24I, L33F, F53LL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89I, T91TS, Q92KF
 RenG15276RenG15276KT746304PINAV32I, M46L, I47AV, I54V, V82T, L90MF53LL10V, K14KR, I15V, G16E, K20R, E35D, M36I, N37D, R41K, K45KR, K55R, R57K, Q61N, L63T, I66F, A71V, I72IT, Q92RF
 RenG15257RenG15257KT746285PINAM46I, I50L, V82AL33F, F53LL10V, T12S, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, L63P, A71VF
 RenG13655RenG13655KT744683PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41P, K55KR, R57K, Q61N, I62V, L63P, A71I, I72IV, V77I, L89TF
 RenG15260RenG15260KT746288PINAM46I, I47V, G48Q, I54V, V82A, L90MF53L, G73TL10V, I15V, K20T, E35N, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, A71V, T74S, I93LF
 RenG14867RenG14867KT745895PINAM46I, I47AL10F, L33LI, F53LT12I, I13V, I15V, Q18E, K20M, E35N, M36I, R41K, K45R, R57K, Q61N, L89IF
 RenG14989RenG14989KT746017PINAI50L, V82AL33F, F53LI13V, I15V, K20R, E35D, M36I, N37IS, R41K, R57K, Q61N, L63T, I64L, K70Q, I72T, T74A, L89MF
 RenG14280RenG14280KT745308PINAI54V, L90ML23I, F53LL10I, K20I, E35N, M36V, R41K, K55KR, R57K, D60E, Q61N, I62IV, L63D, I64IV, E65ED, I66IF, K70R, A71V, I72T, L89M, Q92QK, I93ILF
 RenG13960RenG13960KT744988PINAG48A, I54V, V82AF53LL5LP, W6L, L10I, I13N, I15L, G16E, E35D, M36I, P39S, R41K, K55R, R57K, D60E, Q61D, I62V, H69Y, A71AV, I72R, T74A, L89I, I93ILF
 RenG14620RenG14620KT745648PINAL90MF53L, G73SI13V, I15V, K20T, E35D, M36I, N37T, R41K, R57K, D60E, Q61E, I62V, L63P, A71I, V82I, I93LF
 RenG14753RenG14753KT745781PINAM46I, I47V, I54V, V82AL24I, L33F, K43T, F53LL10I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63AV, I64IL, T74S, L89MF
 RenG12347RenG12347KT743375PINAD30N, M46I, L90MF53L, N88DL10V, I13V, I15V, K20R, E35D, M36I, N37T, P39Q, K55R, R57K, D60E, Q61D, I62V, L63P, A71T, I72TF
 RenG13393RenG13393KT744421PINAD30NL33F, F53L, N88DI15V, L19Q, K20T, E35D, M36I, N37NT, R41K, K45I, R57K, D60E, Q61E, I62V, L63P, I66F, A71V, T74S, V77I, V82I, L89T, Q92RF
 RenG13456RenG13456KT744484PINAI50L, V82AL33F, F53LL10I, I13V, I15V, K20V, E35N, M36I, R41K, K43S, K55R, R57K, Q61N, L63P, H69HY, A71LV, T74SF
 RenG13329RenG13329KT744357PINAN88SF53LG17E, L19I, K20T, E35D, M36I, N37T, R41K, R57K, Q61N, I62V, E65D, A71V, I72V, T74S, V77I, L89M, Q92KF
 RenG11982RenG11982KT743010PINAD30N, M46I, I54V, L90MK43T, F53L, N88DL10R, I15V, K20T, E35D, M36I, R41K, K55KR, R57K, Q61N, I62IV, L63AV, A71V, T74S, V77I, Q92KF
 RenG12457RenG12457KT743485PINAV32I, M46I, I47V, I54ML33F, F53L, G73GSW6V, L10RT, I13IV, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61D, L63P, A71V, I72IT, V77VI, L89TF
 RenG11986RenG11986KT743014PINAM46L, I54V, V82F, L90MF53LL10V, I15V, K20T, E35N, M36I, R41K, K55R, R57K, Q61N, I64V, G68E, A71V, V77I, I93LF
 RenG12671RenG12671KT743699PINAI54L, L90ML23I, F53L, L89VL10V, T12K, I13V, I15V, K20T, E35D, M36I, N37E, R41K, R57K, Q61N, L63P, H69HQ, A71I, T74S, Q92R, I93LF
 RenG12245RenG12245KT743273PINAV32I, M46I, I47V, I54LF53LL10I, I15V, K20T, E35D, M36I, P39T, R57K, D60E, Q61D, I62V, L63E, A71T, I72T, L89MF
 RenG12247RenG12247KT743275PINAI54V, V82AF53LL10V, I15V, G16E, K20R, E35D, M36I, P39T, R41K, K45Q, K55R, R57K, Q61N, L63A, L89MF
 RenG12577RenG12577KT743605PINAM46MI, I47IV, I54V, V82A, L90ML33F, K43KT, F53LL10V, K20R, E35D, M36I, R57K, D60E, Q61N, I62V, L63P, I64V, A71V, I72T, V77I, I93LF
 RenG12550RenG12550KT743578PINAM46L, I54V, V82AL24I, L33F, K43T, F53LL10V, L19I, K20R, E35D, M36I, K55R, R57K, D60E, Q61E, I62V, L63P, A71V, I93LF
 RenG13387RenG13387KT744415PINAI50LL33F, F53LK20R, E34N, E35D, M36I, P39Q, R41K, R57K, Q61N, E65D, I72T, T74A, L89IMF
 RenG12278RenG12278KT743306PINAD30NF53L, N88DL10V, I13V, I15V, K20T, E35D, M36I, Q61N, A71V, T74S, V77I, L89T, Q92RF
 RenG12253RenG12253KT743281PINAV32I, I54LK43T, F53L, L89VL10V, I13V, K20R, E34D, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, A71VF
 RenG12250RenG12250KT743278PINAI54V, V82AV11VI, L33LI, F53LL5LF, W6C, Q7K, T12I, I13V, G16E, K20I, E35D, M36I, R41K, R57K, Q61D, I62V, A71V, I72R, T74A, L89I, T96XF
 RenG13021RenG13021KT744049PINAN88SF53L, Q58EL10I, G16E, K20T, E35D, M36V, N37H, P39S, R41K, R57K, D60E, Q61D, L63C, A71V, V77IL, L89M, I93LF
 RenG12096RenG12096KT743124PINAI50L, V82ML33LF, F53LT12TM, G16E, K20T, E35DN, M36I, N37NT, P39S, R41K, R57K, D60E, Q61DN, L63C, I72V, T74TA, V77I, L89MF
 RenG11186RenG11186KT742214PINAD30N, M46I, L90MF53L, N88DL10V, I13V, I15V, K20R, E35D, M36I, N37T, P39Q, K55R, R57K, D60E, Q61D, I62V, L63P, A71T, I72TF
 RenG11662RenG11662KT742690PINA F53LL10V, K14R, Q18E, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, V77I, I93LF
 RenG10777RenG10777KT741805PINA F53L, N88TK14R, I15V, L19I, K20T, E35D, M36I, R41K, R57K, Q61N, A71V, I85V, L89TF
 RenG11560RenG11560KT742588PINAI54V, V82A, L90MF53LL10I, I15V, K20R, L24F, E34ADNT, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61N, L63P, A71I, I72V, T74S, I93LF
 RenG10902RenG10902KT741930PINAM46I, I54V, V82T, L90MK43T, F53L, G73ST4S, L10I, I15V, E21R, E35D, M36I, R41K, K55R, D60E, Q61D, L63P, A71V, I93LF
 RenG11454RenG11454KT742482PINAM46L, G48A, I54V, V82AL24I, F53LL10I, I15V, L19LV, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, T74A, L89MF
 RenG10140RenG10140KT741168PINAL90LML33F, F53L, N88TI13V, I15V, K20T, E35D, M36I, N37NT, R41K, K55R, R57K, Q61N, A71V, V77I, L89TF
 RenG10656RenG10656KT741684PINAD30N, M46LL23I, F53L, Q58E, N88DL10I, T12I, I13V, I15V, G16E, K20T, E35D, M36V, P39S, R41K, R57K, Q61N, I62V, A71T, I72R, V77I, L89TF
 RenG10500RenG10500KT741528PINAM46L, G48EQ, L90MF53LL10V, I13IV, K14R, G17D, K20T, E35D, M36I, N37D, R41K, R57K, D60DE, Q61N, I64V, E65D, A71V, I72IV, T74TS, V77I, L89M, I93LF
 RenG11122RenG11122KT742150PINAM46L, I54V, L76V, V82AF53LL10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, A71V, I93LF
 RenG11596RenG11596KT742624PINAI50LF53LT12K, I15V, G17E, K20T, E35D, M36I, N37NT, K45Q, K55T, R57K, Q61N, L63P, A71V, I72T, V77I, L89MF
 RenG10276RenG10276KT741304PINAV32I, M46IF53LL10V, K14Q, I15V, G16E, E35D, M36I, P39A, R41K, K43I, Q61N, A71V, I72T, L89MF
 RenG11176RenG11176KT742204PINAM46I, I47V, I54V, V82AF53LL10I, T12S, I13V, K20I, M36D, N37I_D, R41K, R57K, Q61N, T74S, L89MF
 RenG11757RenG11757KT742785PINAL90LML23LI, L33LF, F53LL10LI, I13V, I15V, K20RT, E35D, M36I, N37T, P39PS, R41K, K45R, R57K, Q61D, A71IT, I72T, L89TF
 RenG10845RenG10845KT741873PINAD30N, M46IL23I, L33I, F53L, N88DR8RQ, L10I, I15IV, K20T, E35N, M36I, N37NS, R41K, K45Q, R57K, D60E, Q61N, L63D, I66V, A71T, V77VI, I93LF
 RenG10091RenG10091KT741119PINAM46I, I47V, I54V, V82AF53LL10V, V11VDG, I15V, K20R, E35D, M36I, R41RK, R57K, Q61N, A71V, L89M, I93LF
 RenG11711RenG11711KT742739PINAM46L, I54V, V82AL24I, L33F, K43T, G48E, F53LL10I, I15V, K20M, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, T74S, L89I, Q92KF
 RenG10848RenG10848KT741876PINAV32I, M46I, I47V, I54V, V82AK43T, F53L, G73GCL10V, T12K, I15V, G16E, L19LI, K20R, E34Q, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, V77ILF
 RenG11703RenG11703KT742731PINAM46L, I54V, V82F, L90MF53LL10V, K20R, E35D, M36V, N37NT, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64IV, A71AITV, I72IV, V77I, I85IV, L89IM, I93LF
 RenG10048RenG10048KT741076PINAI54V, V82AL33I, K43T, F53L, N83DI13V, G17A, Q18H, K20R, A22V, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, A71T, I72T, T74A, L89I, T91S, Q92HF