<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I50V
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 25
Isolates 25
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)106671106671AY365754PINAM46I, I50V, V82A, L90ML33F, K43TL10I, I13V, I15V, G16E, K20R, E35D, M36L, R41K, R57K, Q61N, L63S, E65D, A71V, T74S, I93LF
 120891120891AY365993PINAM46I, I50V, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71V, I72TF
 122744122744AY366015PINAM46I, I50V, I54V, V82AF53L, L76ML10I, I15V, K20R, E35D, M36I, R41K, K45R, K55R, R57K, Q61N, L63S, E65D, K70T, A71V, I72E, L89M, I93LF
Rodrigues (2005)BLF_Pat17BR02SP88AY643155SQV, IDV, RTV, NFV, LPV285M46L, I50V, I54V, V82T, L90MK43TL10I, T12N, I15V, L19P, K20R, E21Q, E35D, M36I, N37D, K55R, R57K, Q61N, L63P, A71V, I72V, I85V, L89I, Q92KF
 BLF_Pat23BR03SP224AY643169Unknown, RTV, APV>4M46MI, I50V, I54V, V82A, L90ML23I, F53L, L76ML10I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, I64M, L89M, I93LF
Baxter (2006)48-10081008-30625DQ877332PINAM46I, I50V, I54V, V82AL24I, L33FL10V, T12TN, I15V, E35D, M36I, R41K, R57K, Q61N, I62IV, L63P, A71V, I72TF
 48-12061206-30604DQ877750PINAM46L, I50V, I54V, V82AL24I, L33F, Q58EL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, H69Y, L89MF
 48-61786178-30731DQ878750PINAM46MI, G48GV, I50V, I54V, V82TL33FL10V, I15V, K20R, E35D, M36I, P39PQ, R41K, R57K, Q61N, L63P, T74S, L89M, I93ILF
 48-91969196-30903DQ877572PINAM46I, I50V, I54V, V82AL33I, L76M, N83DL10V, T12E, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I72T, T74S, L89IF
Santos (2006)118118PRAY275778SQV, IDV, RTV, APV, LPV287G48V, I50V, I54S, V82AL33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37D, Q61N, L63T, I85V, L89MF
Dumans (2009)RENA626RENA626FJ405172IDV, SQV, RTV, NFV, LPV335M46L, I50V, I54V, V82T, L90MK43T, L89VL10I, T12N, I15V, L19P, K20R, E21Q, E35D, M36I, N37D, K55R, R57K, Q61N, L63P, A71V, I72V, I85V, Q92KF
 RENA244RENA244FJ405174RTV, SQV, IDV, NFV, Unknown>195M46I, I50V, L76V, V82A, L90M L10V, I15V, K20R, E34A, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, A71V, I93MF
Jones (2012)157415157415JN669882PINAI50V, I54V, V82AL33F, G73CL10I, I13V, K14R, I15V, Q18LM, K20R, E35D, M36I, R41K, K43Q, K45KR, R57RK, Q61N, L63P, I72IT, I93LF
 157416157416JN669883PINAM46I, I50V, I54V, L76V, V82A, L90LMQ58E, L89VL10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, A71V, G73DE, I85V, Q92K, I93LF
 175825175825JN670375PINAI50V, I54V, V82A W6S, L10V, I15V, G16E, K20R, E35D, M36I, N37D, R41K, K45I, R57K, Q61N, L63C, A71V, I72T, I93LF
 175988175988JN670383PINAI50V, I54V, V82A W6S, L10V, I15V, G16E, K20R, E35D, M36I, N37D, R41K, K45I, R57K, Q61N, L63C, A71V, I72T, I93LF
 177288177288JN670432PINAM46I, I50V, I54A, V82A, L90ML33F, Q58E, L89VL10I, I13V, I15V, G16Q, K20R, E35N, M36I, P39Q, R41K, K55R, R57K, Q61N, L63P, A71V, I93ILF
 179245179245JN670506PINAM46I, I50V, I54V, V82AL33LFL10I, T12TM, I15V, G16E, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, A71T, I72RF
 179484179484JN670512PINAM46I, I50V L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63I, I64V, I72MF
 181761181761JN670585PINAM46I, I50V, I54V, L76V, V82T I3F, L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63T, C67W, A71V, I72T, I93LF
 191048191048JN670808PINAM46I, I50V, I54V, V82AL33FL10V, K14KR, I15V, G16GE, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, I72V, T74S, L89MF
 204164204164JN671329PINAM46I, I50VL33LFT12N, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, I64V, I85IVF
 204182204182JN671332PINAM46I, I50V, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, C67CG, A71V, I72TF
 204754204754JN671350PINAM46I, I50V, I54V, V82AL33F, Q58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, L89MF
 207575207575JN671439PINAM46MI, I50VL33FK14S, I15V, K20KT, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, T74A, I85IV, L89MF