<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I50V
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 46
Isolates 46
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)106671106671AY365754PINAM46I, I50V, V82A, L90ML33F, K43TL10I, I13V, I15V, G16E, K20R, E35D, M36L, R41K, R57K, Q61N, L63S, E65D, A71V, T74S, I93LF
 120891120891AY365993PINAM46I, I50V, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71V, I72TF
 122744122744AY366015PINAM46I, I50V, I54V, V82AF53L, L76ML10I, I15V, K20R, E35D, M36I, R41K, K45R, K55R, R57K, Q61N, L63S, E65D, K70T, A71V, I72E, L89M, I93LF
Rodrigues (2005)BLF_Pat17BR02SP88AY643155SQV, IDV, RTV, NFV, LPV285M46L, I50V, I54V, V82T, L90MK43TL10I, T12N, I15V, L19P, K20R, E21Q, E35D, M36I, N37D, K55R, R57K, Q61N, L63P, A71V, I72V, I85V, L89I, Q92KF
 BLF_Pat23BR03SP224AY643169Unknown, RTV, APV>4M46MI, I50V, I54V, V82A, L90ML23I, F53L, L76ML10I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, I64M, L89M, I93LF
Baxter (2006)48-10081008-30625DQ877332PINAM46I, I50V, I54V, V82AL24I, L33FL10V, T12TN, I15V, E35D, M36I, R41K, R57K, Q61N, I62IV, L63P, A71V, I72TF
 48-12061206-30604DQ877750PINAM46L, I50V, I54V, V82AL24I, L33F, Q58EL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, H69Y, L89MF
 48-61786178-30731DQ878750PINAM46MI, G48GV, I50V, I54V, V82TL33FL10V, I15V, K20R, E35D, M36I, P39PQ, R41K, R57K, Q61N, L63P, T74S, L89M, I93ILF
 48-91969196-30903DQ877572PINAM46I, I50V, I54V, V82AL33I, L76M, N83DL10V, T12E, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I72T, T74S, L89IF
Santos (2006)118118PRAY275778SQV, IDV, RTV, APV, LPV287G48V, I50V, I54S, V82AL33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37D, Q61N, L63T, I85V, L89MF
Dumans (2009)RENA626RENA626FJ405172IDV, SQV, RTV, NFV, LPV335M46L, I50V, I54V, V82T, L90MK43T, L89VL10I, T12N, I15V, L19P, K20R, E21Q, E35D, M36I, N37D, K55R, R57K, Q61N, L63P, A71V, I72V, I85V, Q92KF
 RENA244RENA244FJ405174RTV, SQV, IDV, NFV, Unknown>195M46I, I50V, L76V, V82A, L90M L10V, I15V, K20R, E34A, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, A71V, I93MF
Jones (2012)157415157415JN669882PINAI50V, I54V, V82AL33F, G73CL10I, I13V, K14R, I15V, Q18LM, K20R, E35D, M36I, R41K, K43Q, K45KR, R57RK, Q61N, L63P, I72IT, I93LF
 157416157416JN669883PINAM46I, I50V, I54V, L76V, V82A, L90LMQ58E, L89VL10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, A71V, G73DE, I85V, Q92K, I93LF
 175825175825JN670375PINAI50V, I54V, V82A W6S, L10V, I15V, G16E, K20R, E35D, M36I, N37D, R41K, K45I, R57K, Q61N, L63C, A71V, I72T, I93LF
 175988175988JN670383PINAI50V, I54V, V82A W6S, L10V, I15V, G16E, K20R, E35D, M36I, N37D, R41K, K45I, R57K, Q61N, L63C, A71V, I72T, I93LF
 177288177288JN670432PINAM46I, I50V, I54A, V82A, L90ML33F, Q58E, L89VL10I, I13V, I15V, G16Q, K20R, E35N, M36I, P39Q, R41K, K55R, R57K, Q61N, L63P, A71V, I93ILF
 179245179245JN670506PINAM46I, I50V, I54V, V82AL33LFL10I, T12TM, I15V, G16E, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, A71T, I72RF
 179484179484JN670512PINAM46I, I50V L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63I, I64V, I72MF
 181761181761JN670585PINAM46I, I50V, I54V, L76V, V82T I3F, L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63T, C67W, A71V, I72T, I93LF
 191048191048JN670808PINAM46I, I50V, I54V, V82AL33FL10V, K14KR, I15V, G16GE, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, I72V, T74S, L89MF
 204164204164JN671329PINAM46I, I50VL33LFT12N, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, I64V, I85IVF
 204182204182JN671332PINAM46I, I50V, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, C67CG, A71V, I72TF
 204754204754JN671350PINAM46I, I50V, I54V, V82AL33F, Q58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, L89MF
 207575207575JN671439PINAM46MI, I50VL33FK14S, I15V, K20KT, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, T74A, I85IV, L89MF
Diaz (2015)RenG17168RenG17168KT748196PINAV32I, I47A, I50VN83NDL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, V82I, I85V, L89IF
 RenG16609RenG16609KT747637PINAM46I, I50V, I54V, V82AL24LI, L76ML10V, I15V, K20R, E35D, M36I, R41K, K45KR, K55R, R57K, Q61N, L63C, T74S, L89MF
 RenG17232RenG17232KT748260PINAM46I, I47V, I50V, L76V, V82AV11I, L33F, F53LL10V, I13V, I15V, Q18L, L19Q, K20R, E34KNRS, E35D, M36I, N37D, R41K, R57K, Q61N, I66F, A71V, L89I, T91AF
 RenG17309RenG17309KT748337PINAM46I, I50V, V82A, L90ML33F, K43T, F53LL10V, G16E, K20R, E34N, E35D, M36I, P39S, R41K, K55R, R57K, D60E, Q61D, L63HP, A71I, V77I, L89M, I93LF
 RenG16719RenG16719KT747747PINAM46I, I50V I15V, G16GE, K20T, E35D, M36I, R41K, K55R, R57K, Q61N, L63H, V82I, I85V, I93LF
 RenG15742RenG15742KT746770PINAG48V, I50V, I54V, V82A, L90ML33FL10IV, L19I, K20R, E34Q, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I72V, T74S, L89M, I93LF
 RenG17270RenG17270KT748298PINAM46I, I50V, I54V, V82AG73SL10I, K14R, I15V, K20RT, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, A71V, Q92KF
 RenG15700RenG15700KT746728PINAM46I, I50V, I54V, V82A L10V, T12E, K14KQ, I15V, G16GE, L19LI, K20R, E35D, M36I, N37K, R41K, Q61N, L63T, E65D, I72IT, T74AS, L89MF
 RenG16619RenG16619KT747647PINAM46I, I50V, I54V, N88S L10I, I15V, K20T, E35D, M36I, R41K, R57K, Q61D, I62V, L63V, I64V, T74A, L89M, I93LF
 RenG15796RenG15796KT746824PINAG48V, I50V, I54AV, V82AL24LI, L33LF, Q58EL10I, G16GA, K20R, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, L63LP, E65D, V77VI, L89MF
 RenG16638RenG16638KT747666PINAM46I, I50V, I54V, V82AK43TW6L, Q7A, L10V, D25Y, E35D, M36I, R41K, K55R, R57K, Q61N, L63C, A71V, I72V, T74S, L89M, I93LF
 RenG16948RenG16948KT747976PINAM46I, I50V, I54V, V82AK43TL10V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63C, A71V, I72V, T74S, L89M, I93LF
 RenG14503RenG14503KT745531PINAM46I, I50V, I54V, V82A L10I, T12K, I13V, K14R, L19P, K20M, E35D, M36I, R41K, R57K, Q61N, I62IV, I64IV, T74S, L89IF
 RenG13750RenG13750KT744778PINAM46I, G48V, I50V, I54T, V82AL33FL10I, I15V, K20R, E34N, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, I85V, L89I, I93LF
 RenG15008RenG15008KT746036PINAM46I, I50V, I54V, V82AL24I, L76ML10I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, E65D, I72T, T74S, L89MF
 RenG13781RenG13781KT744809PINAM46I, I50V, I54V, L76V L10I, I15V, K20T, E35N, M36I, R41K, R57K, Q61D, I62V, L63V, I64IV, A71V, T74A, V82I, L89M, I93LF
 RenG11890RenG11890KT742918PINAM46I, I50V, I54V, V82AL24I, L76ML10V, I15V, G16A, K20R, E35D, M36I, R41K, K45R, R57K, Q61D, L89MF
 RenG12893RenG12893KT743921PINAM46I, I50V, I54V, V82A, L90MQ58EL10V, I15V, G16E, K20R, E35D, M36V, P39S, R41K, K55R, R57K, D60E, Q61N, L63T, E65D, A71V, I72T, V77VI, L89M, I93LF
 RenG10321RenG10321KT741349PINAM46L, I50V, V82AV11I, L24I, L33F, K43T, F53FL, T74P, L89EIKVL10I, I13V, I15V, K20R, E35D, M36I, N37DE, R41K, R57K, Q61N, I62V, L63LP, G68GE, A71V, I93LF
 RenG11190RenG11190KT742218PINAM46I, I50V, I54V, V82F L10V, I13V, I15V, K20T, E35ED, M36I, N37NK, R41K, R57K, Q61HN, L63DGNS, E65D, I72T, T74A, V77I, L89LMF
 RenG10888RenG10888KT741916PINAM46I, I50V, I54V, V82AL24I, L33FL10V, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63P, T74A, L89MF