<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation G48V
Rx >= 1 PI
IncludeMixtures No
References 12
Patients 30
Isolates 30
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Balotta (2000)CB-231CB-231AF252092SQV, IDV G48V, I54V, V82A L10I, T12N, I15V, K20R, E35D, M36I, R41K, K43I, R57K, Q61N, L63CF
Belec (2000)r31r31_m12AF204352IDV52G48V L10V, I15V, Q18E, E35D, M36I, R41K, K43R, R57K, I62V, L63AF
Apetrei (2003)AC_Pat25RO.01.IS.25AY333503IDV G48V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72TF
de Sa Filho (2003)BREPM046BREPM046AY182794IDV G48V, I54V, V82A L10I, I15V, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, I72IT, T74S, L89IMF
Gomez-Carrillo (2004)9386993869AY365493PINAG48V, I54T, V82A L10I, T12K, Q18E, T26TP, E34Q, E35D, M36I, R41K, K43KN, R57K, Q61N, L63P, A71V, T74S, I93LF
 101053101053AY365625PINAG48V, I54V, V82T, L90M L10I, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I93LF
 102998102998AY365663PINAG48V, I54V, V82S L10V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, H69HY, A71V, V77I, I93LF
 108934108934AY365801PINAG48V, I54V, V82T L10I, K14R, I15V, L19I, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, T74S, I93LF
 119804119804AY365974PINAM46L, G48V, I54V, L76V, V82A, L90ML33F, K43TL10I, I15V, G16E, K20M, E35H, M36L, R41K, K55R, R57K, Q61N, L63S, E65D, A71V, T74S, I93LF
 122345122345AY366009PINAG48V, V82AF53LL10V, I15V, G16E, K20M, E35D, M36I, P39Q, R41K, K55R, R57K, Q61N, L63T, T74AF
Non-B Workgroup (2005)PL36995591 Unknown, LPV>112M46L, G48V, I54V, V82A, L90ML33F, K43TL10V, I15V, G16E, K20M, E35N, M36I, N37ND, R57K, Q61D, G68E, H69R, A71T, I72R, L89I, I93LF
Rodrigues (2005)BLF_Pat24BR02SP255AY643147IDV, SQV, RTV, NFV248M46MI, G48V, I54T, V82A L10I, I15V, L19LI, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, C67D, A71V, I72T, I93LF
Baxter (2006)48-10061006-30609DQ877313PINAG48V, I54V, V82SG73CL10I, I15V, G16E, K20R, E35D, M36I, R41E, R57K, Q61N, I62V, I72R, I93LF
 48-10191019-30619DQ877325PINAG48V, I54V, V82AF53LL10I, I15V, K20R, E35D, M36I, R41K, Q61N, I62IV, L63S, I64L, I72T, T74S, L89M, I93LF
 48-11761176-30901DQ877425PINAM46L, G48V, I54V, V82S L10IV, T12TN, I15IV, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63C, I72V, T74S, I93LF
 48-12711271-30923DQ877792PINAG48V, I54V, V82SL24I, L33F, Q58EL10I, I15V, G16E, K20R, E34Q, E35D, M36I, P39PT, R41K, R57K, I62V, L63T, E65D, I72T, L89MF
Santos (2006)118118PRAY275778SQV, IDV, RTV, APV, LPV287G48V, I50V, I54S, V82AL33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37D, Q61N, L63T, I85V, L89MF
Dumans (2009)RES153_02RES153_02FJ405160RTV, IDV39G48V, I54T, V82A, L90M L10I, T12P, I15V, G16E, K20R, E34A, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, A71V, I72T, T74S, I93LF
 75PR75PRFJ405164NFV104G48V, I54A, V82TK43TL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, L63E, E65D, I72V, L89M, I93LF
Aulicino (2011)ARO26PJARO26PJFJ525871PINAM46L, G48V, I54V, V82AQ58EL10I, K14R, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, Q61N, I62V, L63T, E65D, I72VF
Jones (2012)130379130379JN669485PINAM46L, G48V, I54V, V82S L10I, T12N, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63C, A71AV, I72IV, T74TS, I93LF
 140218140218JN669583PINAG48V, I54V, V82SK43TL10V, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63P, H69Y, A71V, V77I, I93LF
 145007145007JN669651PINAG48V, I54AV, V82TG73GSL10V, I15IV, G17D, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I93LF
 147132147132JN669688PINAG48V L10V, I15V, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, I72T, T74SF
 167998167998JN670168PINAI47V, G48V, I54A, V82A L10I, G16E, K20R, E35D, M36I, N37NT, P39S, K43I, R57K, Q61N, I62V, L63T, H69Y, A71V, Q92K, I93LF
 169081169081JN670190PINAM46L, G48V, I54V, V82S, I84V L10V, I15V, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63C, A71V, I72V, T74S, I93LF
 172335172335JN670285PINAG48V, I54V, V82AT, L90MF53FL, G73GSL10V, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61DN, A71V, I72R, I93LF
 190292190292JN670792PINAG48V, L90M L10I, T12M, I15V, Q18E, E35D, M36I, R41K, R57K, Q61D, L63P, H69HY, A71I, I72T, I93LF
 192437192437JN670851PINAG48V, I54V, V82S L5LP, L10V, I15V, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, I64L, A71V, Q92R, I93LF
 201239201239JN671217PINAG48V, I54V, V82ATQ58EL10V, I15V, G16E, K20R, E35D, M36I, P39PS, R41K, R57K, Q61N, L63AF