<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation G48V
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 32
Isolates 32
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Balotta (2000)CB-231CB-231AF252092SQV, IDV G48V, I54V, V82A L10I, T12N, I15V, K20R, E35D, M36I, R41K, K43I, R57K, Q61N, L63CF
Belec (2000)r31r31_m12AF204352IDV52G48V L10V, I15V, Q18E, E35D, M36I, R41K, K43R, R57K, I62V, L63AF
Apetrei (2003)AC_Pat25RO.01.IS.25AY333503IDV G48V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72TF
de Sa Filho (2003)BREPM046BREPM046AY182794IDV G48V, I54V, V82A L10I, I15V, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, I72IT, T74S, L89IMF
Gomez-Carrillo (2004)103840103840AY365687PINAG48V, I54V, V82A, L90M L10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63T, E65D, I72T, T74SF
Non-B Workgroup (2005)PL36995591 Unknown, LPV>112M46L, G48V, I54V, V82A, L90ML33F, K43TL10V, I15V, G16E, K20M, E35N, M36I, N37ND, R57K, Q61D, G68E, H69R, A71T, I72R, L89I, I93LF
Rodrigues (2005)BLF_Pat24BR02SP255AY643147IDV, SQV, RTV, NFV248M46MI, G48V, I54T, V82A L10I, I15V, L19LI, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, C67D, A71V, I72T, I93LF
Baxter (2006)12-13091309-30505DQ876224PINAG48V, I54V, L90MK43TL10I, I15V, G16E, K20R, E35D, M36I, P39S, R41K, I62V, L63C, I93LF
 48-10191019-30619DQ877325PINAG48V, I54V, V82AF53LL10I, I15V, K20R, E35D, M36I, R41K, Q61N, I62IV, L63S, I64L, I72T, T74S, L89M, I93LF
 48-11391139-30814DQ877399PINAM46L, G48V, I54T, V82AL24IL10I, K20R, E35D, M36I, N37DE, R41K, K43R, R57K, Q61N, L63C, T74S, L89MF
 48-12711271-30923DQ877792PINAG48V, I54V, V82SL24I, L33F, Q58EL10I, I15V, G16E, K20R, E34Q, E35D, M36I, P39PT, R41K, R57K, I62V, L63T, E65D, I72T, L89MF
Santos (2006)118118PRAY275778SQV, IDV, RTV, APV, LPV287G48V, I50V, I54S, V82AL33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37D, Q61N, L63T, I85V, L89MF
Waleria-Aleixo (2008)08PR04018508PR040185FJ591216PINAG48V, I54V, V82A, L90MK43TL10V, G17E, K20I, E35D, M36I, N37E, R41K, R57K, Q61D, I62V, A71V, I72R, T74S, L89I, I93LF
 08RJ06057808RJ060578FJ591738PINAM46L, G48V, I54ST, V82ASK43KT, F53FLL10I, G16A, L19V, K20R, E35D, M36I, R41K, R57K, Q61N, E65D, T74S, L89MF
Dumans (2009)75PR75PRFJ405164NFV104G48V, I54A, V82TK43TL10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, L63E, E65D, I72V, L89M, I93LF
Jones (2012)147132147132JN669688PINAG48V L10V, I15V, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, I72T, T74SF
 167998167998JN670168PINAI47V, G48V, I54A, V82A L10I, G16E, K20R, E35D, M36I, N37NT, P39S, K43I, R57K, Q61N, I62V, L63T, H69Y, A71V, Q92K, I93LF
Diaz (2015)RenG15534RenG15534KT746562PINAG48V, I54S, V82AK43TL10I, I15V, K20R, E35D, M36I, N37NS, R41RK, R57K, Q61N, I62V, A71V, I72T, T74S, L89I, I93LF
 RenG15742RenG15742KT746770PINAG48V, I50V, I54V, V82A, L90ML33FL10IV, L19I, K20R, E34Q, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I72V, T74S, L89M, I93LF
 RenG16345RenG16345KT747373PINAG48V, I54V, V82AL24I, F53LL10I, G16GE, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63PT, E65D, I72IT, L89MF
 RenG15796RenG15796KT746824PINAG48V, I50V, I54AV, V82AL24LI, L33LF, Q58EL10I, G16GA, K20R, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, L63LP, E65D, V77VI, L89MF
 RenG14436RenG14436KT745464PINAM46L, G48V, I54V, V82AL24IL10V, I15V, L19I, K20R, E35D, M36I, N37D, R41K, F53Y, K55R, R57K, D60E, Q61E, I62V, L63P, A71T, I72T, T74TA, L89I, T91SF
 RenG13750RenG13750KT744778PINAM46I, G48V, I50V, I54T, V82AL33FL10I, I15V, K20R, E34N, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, I85V, L89I, I93LF
 RenG14943RenG14943KT745971PINAG48V, I54V, V82A, L90ML33FL10IV, I13V, K14R, I15V, K20M, E35D, M36I, N37I, R41K, R57K, Q61N, T74S, L89I, Q92K, I93L, C95FF
 RenG14761RenG14761KT745789PINAD30N, G48V, I54V, V82AL24I, L33F, F53LL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89I, T91TS, Q92KF
 RenG15104RenG15104KT746132PINAG48V, I54V, V82A, L90ML33LFL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37NIK, R41K, R57K, Q61N, T74S, L89I, Q92K, I93L, C95FF
 RenG13694RenG13694KT744722PINAV32I, I47V, G48V, I54V, V82A, L90ML33F, F53L, Q58E, L89VL10I, I13V, K14E, I15V, K20R, E34Q, E35D, M36I, N37D, R41K, K55R, V56I, R57K, D60E, I62V, L63P, A71V, I85V, Q92KF
 RenG13889RenG13889KT744917PINAG48V, I54T, V82AK43KTL10I, T12S, I13V, K20M, E35D, M36I, R41K, R57K, Q61N, T74S, L89I, N98K, F99FLF
 RenG13954RenG13954KT744982PINAM46L, G48V, I54V, V82SL33IL10I, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, L89MF
 RenG11817RenG11817KT742845PINAG48V, I54S, V82ACGSV11I, L33LF, T74PSL10I, T12K, I13V, K14R, I15V, K20T, E35N, M36I, R41P, R57K, Q61N, L89IF
 RenG11279RenG11279KT742307PINAG48V, I54V, L76V, V82A, I84VM46V, Q58EL10I, I15V, G16E, K20R, E35D, M36I, K55R, R57K, Q61N, L63C, L89IF
 RenG11078RenG11078KT742106PINAG48V, I50L, I54V, V82A L10V, K14R, I15V, L19V, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, G68D, A71AT, I85V, L89IF