<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation I47V
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 53
Isolates 53
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)9764497644AY365553PINAV32I, M46I, I47V, V82AL24I, L89VL10I, T12N, I15V, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, A71T, V77I, I93LF
 113771113771AY365884PINAI47V, I54M, L90M L10I, I13IV, I15V, K20I, E35DN, M36I, R41K, R57K, Q61N, L63P, T74S, V82VI, I85VF
 126743126743AY366057PINAV32I, M46I, I47V, I54V, V82AL24I, L33F, F53LL10V, I15V, K20R, E34V, E35D, M36I, R41K, Q61N, I62V, L63P, T74S, L89M, Q92KF
Baxter (2006)48-11361136-30729DQ877275PINAM46I, I47V, I54V, V82FL33F, K43T, N88D, L89LVL10I, I15V, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, A71V, I85V, I93LF
 48-10071007-30609DQ877312PINAM46I, I47V, I54V, V82A, L90MF53LL10V, L19LI, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, I62V, L63LP, A71V, I85V, I93LF
 48-10741074-30626DQ877334PINAV32I, M46I, I47V, I54V, V82A, L90LML24I, L33F, T74PSL10I, I13IV, I15IV, G16E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63S, E65D, A71AV, V77I, L89M, Q92QK, I93LF
 48-10271027-30707DQ877408PINAV32I, M46I, I47V, I54V, V82AL24I, L33F, F53LL10V, I15V, K20R, E34V, E35D, M36I, R41K, Q61N, I62V, L63P, T74S, L89M, Q92KF
 48-10551055-30707DQ877421PINAM46I, I47V, I54V, V82F, L90MF53FLL10I, K20I, E35D, M36V, R41K, R57K, Q61N, I62IV, L63Q, I64IV, A71V, T74S, I93LF
 48-11801180-30922DQ877428PINAV32I, M46I, I47V, I54M, L90MF53LL10I, I15V, K20I, E35N, M36I, R41K, R57K, Q61N, L63P, I72IV, T74S, V82I, I85V, L89LIF
 48-93499349-30923DQ877289PINAV32I, M46I, I47V, G48M, I54M, V82AL33F, F53LL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, T74S, L89IF
 48-90949094-30827DQ877653PINAV32I, M46I, I47V, I54V, V82AL24LI, L33F, Q58EL10I, I15V, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63PF
Aulicino (2011)ARM36WMRARM36WMRFJ525826PINAM46I, I47V, I54V, V82AL24I, K43T, F53LL10V, G16X, K20R, E35D, M36I, K55R, R57K, Q61N, L63T, H69R, T74S, L89MF
Jones (2012)149561149561JN669737PINAM46I, I47V, I54V, V82A L10V, T12TA, I15V, K20RS, E35D, M36I, R41K, R57K, Q61D, L63PF
 158844158844JN669935PINAM46I, I47V, I54V, V82SL23I, K43T, F53LL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63A, A71V, I72V, T74S, L89M, I93LF
 163933163933JN670073PINAM46I, I47V, I54V, V82F, L90ML89VL10I, I15V, G17D, K20T, E35N, M36I, R41K, K55KR, R57K, Q61N, I62V, L63P, T74S, V77I, I85V, I93LF
 167774167774JN670161PINAV32I, I47V, I54M, N88S, L90LML33F, G73S, L89VT12I, I13V, I15V, G16E, K20R, E35ED, M36I, R41K, R57K, Q61N, G68GE, A71IV, I72T, V77VEF
 167998167998JN670168PINAI47V, G48V, I54A, V82A L10I, G16E, K20R, E35D, M36I, N37NT, P39S, K43I, R57K, Q61N, I62V, L63T, H69Y, A71V, Q92K, I93LF
 181091181091JN670565PINAM46I, I47V, I54V, L76V, V82AQ58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I72T, I93LF
 189227189227JN670768PINAM46I, I47V, I54V, L76V, V82A L10V, T12TK, I15V, G16E, L19I, K20R, E35D, M36I, R41K, K45R, K55KR, R57K, Q61N, L63T, A71V, I72T, I93LF
 196870196870JN671042PINAV32I, M46I, I47V, I54V, V82A, L90LMF53L, G73CL10I, I15V, G16A, K20R, E35D, M36I, N37ND, R41K, K55R, R57K, Q61N, L63P, A71AV, V77VI, I93ILF
 198351198351JN671114PINAM46I, I47V, I54V, V82SF53LL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63Q, I64L, A71V, I93LF
 202348202348JN671268PINAV32I, M46MI, I47V, I54IML33LFL10I, I15V, G16GE, E35D, M36I, R41K, R57K, Q61D, L63I, I72IT, V82I, I93LF
Diaz (2015)RenG17206RenG17206KT748234PINAM46I, I47V, I54V, V82A, L90ML33F, F53L, Q58EL10I, I13V, Q18IL, L19V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I66F, A71T, I72IM, L89I, Q92KF
 RenG17085RenG17085KT748113PINAM46L, I47V, I54V, V82AL24I, L33F, F53L, Q58EL10I, G16A, K20R, E34EV, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63D, E65D, A71V, I72T, I93LF
 RenG15931RenG15931KT746959PINAM46I, I47V, I54V, V82AK43T, F53LL10I, T12E, L19I, K20R, E35D, M36I, N37T, R41K, K55R, R57K, Q61N, I62V, L63T, I66F, I72V, T74S, V77VI, L89I, T91S, Q92K, F99FLF
 RenG16151RenG16151KT747179PINAV32I, M46I, I47V, I54A, V82AL76ML10I, I15V, L19I, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, I62IV, L63V, I64L, A71I, I72T, L89M, I93LF
 RenG17232RenG17232KT748260PINAM46I, I47V, I50V, L76V, V82AV11I, L33F, F53LL10V, I13V, I15V, Q18L, L19Q, K20R, E34KNRS, E35D, M36I, N37D, R41K, R57K, Q61N, I66F, A71V, L89I, T91AF
 RenG16754RenG16754KT747782PINAV32I, M46I, I47V, I54M, V82VA, I84V, L90MV11I, L33F, K43TL10IV, I13V, E34K, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, I85IV, L89M, Q92QRF
 RenG17442RenG17442KT748470PINAM46I, I47V, I54V, V82F, L90MK43TL10I, I13V, K14R, I15V, K20T, E35N, M36I, R41K, R57K, D60E, Q61D, I72T, V77I, L89IF
 RenG17332RenG17332KT748360PINAV32I, M46L, I47V, V82FF53LL10I, K20R, E35D, M36I, N37S, R41K, R57K, Q61N, L63T, E65D, A71I, I72T, V77I, I85V, I93LF
 RenG17240RenG17240KT748268PINAV32I, M46I, I47V, I54M, L90ML33F, F53L, L89VL10I, I13V, I15V, L19V, K20R, E35D, M36I, N37DE, R41K, G51A, R57K, Q61N, I66F, A71V, G73N, V77I, V82IF
 RenG14507RenG14507KT745535PINAM46I, I47V, I54V, V82AF53L, Q58EL10V, K14R, G17E, L19V, K20R, E35D, M36I, N37D, R41RK, K55R, R57K, Q61N, L63T, E65D, I72T, V77I, L89MF
 RenG14903RenG14903KT745931PINAM46I, I47V, I54V, V82AF53LL10I, I15V, G16E, K20M, E35D, M36V, R57K, Q61N, E65D, A71V, I72T, I93LF
 RenG14526RenG14526KT745554PINAD30N, M46I, I47V, I54V, V82A, L90ML33F, F53L, Q58E, N88DL10V, T12K, I15V, G16Q, K20T, E35S, M36I, P39S, R41K, K45R, R57K, D60E, Q61D, L63P, A71I, L89IF
 RenG13828RenG13828KT744856PINAM46I, I47V, I54V, V82T, I84VL33F, K43T, F53L, T74PL10I, I13IV, K20R, E35D, M36I, N37ND, R41K, D60DE, Q61N, I62IV, L63P, A71V, Q92QRF
 RenG13656RenG13656KT744684PINAV32I, M46I, I47V, I54V, V82A, L90ML10F, Q58EI15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61N, L63P, A71V, L89I, I93LF
 RenG15260RenG15260KT746288PINAM46I, I47V, G48Q, I54V, V82A, L90MF53L, G73TL10V, I15V, K20T, E35N, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, A71V, T74S, I93LF
 RenG14046RenG14046KT745074PINAI47V, G48A, I54A, V82AS L10I, I15V, G16GE, K20R, E35D, M36I, N37ND, R41K, K43KR, K45KR, R57K, Q61N, L63Q, A71V, I85V, L89I, Q92K, I93LF
 RenG15368RenG15368KT746396PINAV32I, I47V, I50LL33F, G73SL10I, T12N, I15V, L19I, E35D, M36I, N37E, R57K, Q61N, I62V, L63A, I66L, Q92HF
 RenG14753RenG14753KT745781PINAM46I, I47V, I54V, V82AL24I, L33F, K43T, F53LL10I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63AV, I64IL, T74S, L89MF
 RenG12463RenG12463KT743491PINAM46I, I47V, I54V, V82A L10I, I15V, L19I, K20KR, E35D, M36I, R41K, R57K, Q61N, I85IV, L89M, T91TIF
 RenG13104RenG13104KT744132PINAM46I, I47V, I54V, V82AL24I, L33IL10V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, L89I, Q92K, N98IF
 RenG12483RenG12483KT743511PINAV32I, I47V, G48M, I54T, V82AL33F, Q58EL10V, T12I, I13IV, I15V, K20R, E34N, E35D, M36I, N37E, R41K, R57K, D60E, Q61N, I62V, I72V, T74S, V77VI, L89MF
 RenG12585RenG12585KT743613PINAM46I, I47V, I54V, V82AK43KTL10V, I15V, G16AE, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72TF
 RenG12457RenG12457KT743485PINAV32I, M46I, I47V, I54ML33F, F53L, G73GSW6V, L10RT, I13IV, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61D, L63P, A71V, I72IT, V77VI, L89TF
 RenG12258RenG12258KT743286PINAM46I, I47V, I54V, V82AQ58EL10V, K20R, E35DN, M36I, N37DE, R41K, R57K, Q61N, I62IV, E65D, I72V, L89MF
 RenG11995RenG11995KT743023PINAV32I, M46I, I47V, I54A, V82A L10I, T12A, I15V, L19P, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, I64V, A71V, Q92KF
 RenG12245RenG12245KT743273PINAV32I, M46I, I47V, I54LF53LL10I, I15V, K20T, E35D, M36I, P39T, R57K, D60E, Q61D, I62V, L63E, A71T, I72T, L89MF
 RenG12669RenG12669KT743697PINAM46I, I47V, I54V, V82AF53FLL10I, I15IGRV, K20R, E35D, M36I, R41K, R57K, Q61N, L63G, I72IR, L89MF
 RenG11176RenG11176KT742204PINAM46I, I47V, I54V, V82AF53LL10I, T12S, I13V, K20I, M36D, N37I_D, R41K, R57K, Q61N, T74S, L89MF
 RenG10824RenG10824KT741852PINAV32I, M46I, I47V, I54M, V82A, L90MV11I, L33F, K43T, F53FLL10V, I13V, E34R, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, L89M, Q92RF
 RenG10091RenG10091KT741119PINAM46I, I47V, I54V, V82AF53LL10V, V11VDG, I15V, K20R, E35D, M36I, R41RK, R57K, Q61N, A71V, L89M, I93LF
 RenG10848RenG10848KT741876PINAV32I, M46I, I47V, I54V, V82AK43T, F53L, G73GCL10V, T12K, I15V, G16E, L19LI, K20R, E34Q, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, V77ILF