<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation M46L
Rx >= 1 PI
IncludeMixtures No
References 17
Patients 166
Isolates 167
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Apetrei (2003)AC_Pat7RO.00.IS.07AY333458IDV, SQV, NFV, UnknownNAM46L, I54V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.07AY333459IDV, SQV, NFV, UnknownNAM46L, I54V, V82A L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
 AC_Pat36RO.00.IS.36AY333461IDV, RTV, SQV, NFV M46L, I54V, V82A L10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, K70E, I72T, L89MF
de Sa Filho (2003)BREPM174BREPM174AY182828IDV V32I, M46L, V82A L10I, G16E, N37S, R41K, R57K, Q61D, L63S, E65D, A71VF
Gomez-Carrillo (2004)101216101216AY365629PINAM46L, I54V, V82A I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, Q61NF
 103183103183AY365671PINAD30N, M46L, I54V, V82A, L90ML33F, N88DI13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63H, A71V, T74S, I93LF
 105436105436AY365727PINAM46L, I54V, L76V, V82AL23LIL10I, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63C, L89MF
 113812113812AY365885PINAM46L, I54V, V82A L10LV, I15V, K20KR, E35D, M36I, R41K, R57K, Q61D, I62V, A71AV, L89I, I93LF
 120835120835AY365991PINAM46L, V82AL24IK14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, H69QF
Machado (2004)cs133cs133AY313342RTV155M46L, I54V, V82AL24IL10I, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, L89MF
Machado (2004)CS172proCS172proAY502095Unknown, NFV>21M46LN83DG16E, M36L, N37K, R41K, R57K, Q61D, I72R, L89IF
Thomson (2004)99UFRJ_999UFRJ_9AY455783IDV87D30N, M46L E21K, E34K, E35N, M36I, R41K, R57K, Q61H, L89MF
Non-B Workgroup (2005)PL36995591 Unknown, LPV>112M46L, G48V, I54V, V82A, L90ML33F, K43TL10V, I15V, G16E, K20M, E35N, M36I, N37ND, R57K, Q61D, G68E, H69R, A71T, I72R, L89I, I93LF
Rodrigues (2005)BLF_Pat8BR03SP01AY643156Unknown, RTV, IDV>51M46L, I54A, V82AL24I, K43TL10I, I15V, L19I, K20R, E35D, M36I, K55R, R57K, Q61N, L63P, A71V, I85V, L89IF
 BLF_Pat17BR02SP88AY643155SQV, IDV, RTV, NFV, LPV285M46L, I50V, I54V, V82T, L90MK43TL10I, T12N, I15V, L19P, K20R, E21Q, E35D, M36I, N37D, K55R, R57K, Q61N, L63P, A71V, I72V, I85V, L89I, Q92KF
 BLF_Pat22BR03SP87AY643178RTV, NFV, APV217M46L, I54V, V82AL24I, Q58EL10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P, T74A, L89MF
 BLF_Pat33BR03SP36AY643174SQV, NFV, IDV129M46LL10F, N88TK14R, I15V, K20T, E35N, M36I, R41K, R57K, Q61N, I72V, L89MF
Baxter (2006)48-11621162-30814DQ877267PINAM46L, I54V, L76V, V82AL23IL10I, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, L63C, L89MF
 48-11391139-30814DQ877399PINAM46L, G48V, I54T, V82AL24IL10I, K20R, E35D, M36I, N37DE, R41K, K43R, R57K, Q61N, L63C, T74S, L89MF
 48-12061206-30604DQ877750PINAM46L, I50V, I54V, V82AL24I, L33F, Q58EL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, H69Y, L89MF
 48-20132013-30324DQ877845PINAM46L, I54V, V82AL24I, Q58QEL10V, I15V, K20R, E35D, M36I, I62V, L63T, I72T, T74A, L89MF
 48-61196119-30924DQ878705PINAM46L, I54V, V82AL24IL10V, T12P, G17D, K20R, E35D, M36I, R57K, Q61N, L63S, I72T, L89MF
 48-92729272-30922DQ877288PINAM46L, I54V, V82A, L90LM L10I, I15V, L19Q, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, T74A, L89I, I93LF
 48-91869186-30901DQ877291PINAM46L, I54V, V82AL24I, L33F, K43T, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I64L, A71V, I72T, L89I, I93LF
 48-92899289-30930DQ877308PINAM46L, I54V, V82A, I84IVL24I, L33LFL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63LP, A71V, L89M, Q92K, I93LF
 48-92669266-30915DQ877516PINAM46L, I54V, L76V, V82A, L90M L10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, H69R, K70R, A71V, I72IV, L89M, I93LF
 48-92509250-30908DQ877602PINAM46L, I54V, V82AV11VI, L24I, L33F, T74PL10I, I13V, G17E, L19I, K20R, E35D, M36I, R41K, R57K, Q61DN, I62V, L63T, E65D, I72T, L89MF
 48-91119111-30918DQ877698PINAM46L, I54V, V82AV11I, L24I, G73SL10I, A22V, E35D, M36I, N37D, R41K, K55KR, R57K, D60E, Q61D, I62V, L63P, A71V, I72TF
 48-91499149-30826DQ877714PINAM46L, I54V, V82AL24I, L33F, K43T, F53LR8P, L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, K70R, L89LM, Q92KF
 48-91299129-30918DQ877727PINAM46L, I54V, V82A, L90MK43KTR8RG, L10IV, L19I, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61N, I62V, L63P, E65D, I72V, L89MF
Sanabani (2006)01BR08701BR087DQ358801PINAM46L, V82A I15V, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L89MF
Waleria-Aleixo (2008)08PR05033408PR050334FJ591362PINAM46L, I54V, V82FL33I, Q58EL10I, I13V, A22V, E35D, M36I, R41K, Q61N, I62V, L63I, I64V, H69R, K70R, L89MF
 08PR05033108PR050331FJ591359PINAM46L, I54V, V82AL24I, K43T, F53LL10I, K14R, L19I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, E65D, I72AT, T74S, L89MF
 RES304RES304FJ591995PINAM46L, I54V, V82AL24IL10I, I13IV, K20R, A22AV, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, A71V, Q92KF
 08PR05031308PR050313FJ591341PINAM46L, L90ML33F, G73GAL10V, I13IV, I15V, K20T, E35D, M36I, R41K, K55KR, R57K, Q61N, L63P, E65ED, C67CY, A71T, I72T, I85VF
 08RJ06066908RJ060669FJ591784PINAM46L, I54V, V82A, L90MT74PL10V, G17E, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63T, E65D, I72T, L89MF
 08RJ06057808RJ060578FJ591738PINAM46L, G48V, I54ST, V82ASK43KT, F53FLL10I, G16A, L19V, K20R, E35D, M36I, R41K, R57K, Q61N, E65D, T74S, L89MF
 08RJ05046408RJ050464FJ591658PINAM46L, I54V, I84V, L90MN88DL10I, I15V, K20T, E35D, M36I, P39Q, R41K, K45R, R57K, Q61N, L63P, I66F, K70R, A71V, I72V, V77I, L89M, Q92KF
Dumans (2009)RENA596RENA596FJ405130IDV, Unknown, NFV, LPV>322M46L, I54V, V82A L10V, I15V, E35D, M36I, R41K, R57K, Q61N, I72T, L89MF
 RENA502RENA502FJ405148IDV, SQV, RTV, NFV244M46L, V82A L10V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, L89MF
 RES28_02RES28_02FJ405158IDV, NFV, RTV, APV139M46L, I54V, V82AL33FL10I, G17D, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, L89MF
 RES304_03RES304_03FJ405159IDV, NFV, LPV295M46L, I54V, V82AL24IL10I, K20R, A22AV, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, A71V, Q92KF
 59PR59PRFJ405165Unknown, NFV>27M46L, I54V, V82AL24IL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, I85V, L89MF
 RENA651RENA651FJ405167RTV, IDV300M46L, I54V, V82A L10V, T12I, I13V, I15V, G16E, K20R, N37S, R57K, Q61N, L63S, E65D, L89MF
 RENA626RENA626FJ405172IDV, SQV, RTV, NFV, LPV335M46L, I50V, I54V, V82T, L90MK43T, L89VL10I, T12N, I15V, L19P, K20R, E21Q, E35D, M36I, N37D, K55R, R57K, Q61N, L63P, A71V, I72V, I85V, Q92KF
 RENA181RENA181FJ405173IDV213M46L, I54V, V82AL24IL10I, I15V, E35D, M36I, P39T, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71V, L89I, I93LF
Sanabani (2009)56406BR564FJ771008PINAM46L, V82AK43TL10M, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, T74S, I85V, L89TF
Aulicino (2011)ARM144EJAARM144EJAFJ525825PINAM46L K14KR, I15V, K20I, E35D, M36I, R41K, R57K, Q61DN, L63P, E65D, T74S, L89MF
 ARN272RLDARN272RLDFJ525856PINAM46L, I54V, V82TL33F, N83DL10I, T12E, E35D, M36L, R41K, K55R, R57K, Q61N, L63P, I64M, K70T, A71V, I72T, Q92KF
 3006-M668AS3006-M668ASHQ158167PINAM46L T12Q, K14R, I15V, M36I, R41K, K43R, Q61N, L63P, I72V, Q92TF
Jones (2012)132888132888JN669516PINAM46L, I54V, V82A L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, I62V, A71V, I72T, L89I, I93LF
 160595160595JN669984PINAM46L, I54V, V82A, L90MQ58EL10V, I15V, K20R, E35D, M36I, Q61N, I62IV, L63P, I72V, R87RK, L89M, Q92KF
 166492166492JN670129PINAD30N, M46LN88DI15V, L19LQ, K20T, E35D, M36I, R41K, R57K, Q61N, I64IV, E65D, A71V, I72TF
 179417179417JN670509PINAM46L, V82AN88DG16E, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63H, I64IL, A71VF
 180897180897JN670557PINAM46L, I54V, V82AL24IL10I, T12N, L19LI, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, I62IV, A71V, I72RF
 181788181788JN670587PINAM46L, I54V, V82AL24IL10I, T12N, I15V, L19I, E35D, M36I, R41K, K55KR, Q61N, L63S, A71VF
 182552182552JN670618PINAM46L I15V, E35D, M36I, R41K, K55R, R57K, Q61SF
 183349183349JN670642PINAM46L, I54V, L76V, V82A L10I, T12I, I15V, G16E, L19I, K20M, E35DN, M36I, R41RK, R57K, Q61N, L63LH, I85V, L89IF
 187322187322JN670731PINAM46L, V82A I15V, G16E, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, L63T, E65D, I72T, T74SF
 202350202350JN671269PINAM46L, I54A, V82AL89VL10I, T12I, I13V, I15V, G16A, L19P, K20L, E35D, M36I, N37ND, R41RK, K45KR, K55KR, R57K, Q61D, A71V, I72TF
 204494204494JN671343PINAM46L, I54V, V82AL24IL10V, T12N, I15V, K20R, E35D, M36I, R41K, Q61N, L63T, E65D, I72TF
 206318206318JN671397PINAM46L, I54V, V82A, I84VV11I, L24I, L33LF, K43TL10I, I15V, G16E, L19I, K20R, E35D, M36IV, K55R, R57K, Q61N, L63N, A71T, I72T, T91SF
 207640207640JN671442PINAM46L, G48AEKT, I54V, V82M, I84VL24I, L33I, K43T, F53FLL10I, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63IT, E65D, I72T, T74S, P79PS, L89MF
Kouri (2012)CU2073-09CU2073-09JQ585339PINAM46L, I54V, V82AF53LL10I, I13V, G16E, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, Q61H, L63T, E65D, I72T, T74A, L89MF
 CU772-10CU772-10JQ585416PINAM46L, I54AV, V82AL33F, T74AP, N83NDL10I, I13V, I15IV, G16E, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, L89MF
Diaz (2015)RenG16649RenG16649KT747677PINAM46L, I54V, V82A, L90MK43T, T74PL10IV, T12K, I13V, K14KR, I15V, K20I, E35N, M36I, R41K, Q61N, L63T, E65D, I72T, L89MF
 RenG15726RenG15726KT746754PINAM46L, I54V, V82A, I84V, L90ML33F, K43KPQT, F53FL, T74PSL10V, I13V, I15V, K20R, E35D, M36I, N37D, P39PT, R41RK, K55KR, R57K, Q61N, I62V, L63P, I64L, H69HR, A71IT, L89MT, Q92KF
 RenG17165RenG17165KT748193PINAV32I, M46L, I47IV, I54LV, V82A, I84VL24I, L33FL10I, I13V, G17D, L19I, K20R, E35D, M36I, K43I, R57K, Q61N, L63V, E65D, I72T, T74S, V77IL, L89MF
 RenG16096RenG16096KT747124PINAM46L, I54V, V82AL24I, K43T, F53LL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, T74S, L89MF
 RenG16531RenG16531KT747559PINAM46L, I54V, I84V, L90MG73SL10I, K20I, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I85V, L89T, Q92KF
 RenG16492RenG16492KT747520PINAM46L, I54V, V82AL24I, L33F, K43T, T74PL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, H69R, Q92KF
 RenG16248RenG16248KT747276PINAM46L, I54V, L76V, V82A, L90ML23IL10I, I13V, I15V, K20I, E35N, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I64L, A71V, I72V, T74S, I93LF
 RenG17261RenG17261KT748289PINAM46L, I54V, V82A, L90MF53FLL10I, I15V, L19I, K20R, E35D, M36I, N37NY, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, L89M, I93LF
 RenG17432RenG17432KT748460PINAM46L, I54V, V82AL10F, L24I, F53FLI15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I64L, T74S, L89M, N98IF
 RenG16869RenG16869KT747897PINAM46L, I54V, V82A, L90ML33IL10V, T12K, I13V, K20R, E35D, M36I, R41K, F53I, K55N, R57K, D60E, Q61N, I62V, L63S, A71T, L89I, Q92KF
 RenG15928RenG15928KT746956PINAM46L, I54V, V82AL24I, Q58E, G73SL10I, T12N, I15V, L19P, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, L63P, A71V, I72LF
 RenG16262RenG16262KT747290PINAM46L, I54V, V82AL10F, L24I, K43TI13M, K20I, E35D, M36I, N37E, K55R, R57K, D60E, Q61N, L63P, I72V, L89IF
 RenG15968RenG15968KT746996PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG16704RenG16704KT747732PINAM46L, V82A L10I, T12D, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63A, E65D, L89MF
 RenG17332RenG17332KT748360PINAV32I, M46L, I47V, V82FF53LL10I, K20R, E35D, M36I, N37S, R41K, R57K, Q61N, L63T, E65D, A71I, I72T, V77I, I85V, I93LF
 RenG15729RenG15729KT746757PINAM46L, I54V, L76V, V82AL33FL5LF, W6L, L10V, I13V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, G68D, L89IF
 RenG16739RenG16739KT747767PINAM46L, I54V, V82AL24I, L33F, T74PL10IV, I13V, K20R, E35D, M36I, N37D, R41K, K55T, R57K, Q61N, I64L, L89MF
 RenG17047RenG17047KT748075PINAM46L, I50L, V82A, L90MQ58EL10I, I15V, G17D, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64V, A71T, L89M, I93LF
 RenG16629RenG16629KT747657PINAM46L, I54A, V82AL24I, L33F, K43KT, N83NDL10IV, I13V, G16E, K20R, E35DN, M36I, N37DE, R41K, K55KR, R57K, Q61N, L63NT, I64IL, A71IV, I72T, I93LF
 RenG17358RenG17358KT748386PINAM46L, I50V, I54IV, V82VAL33F, Q58EL10V, I13IV, I15V, L19I, K20R, E35D, M36I, R41K, K55R, R57K, I62V, L63P, T74S, L89MF
 RenG16312RenG16312KT747340PINAM46L, I47A, L90M I13V, I15V, K20MT, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71T, I72T, V82I, L89I, I93LF
 RenG16968RenG16968KT747996PINAM46L, I54V, L76V, V82A, L90M R8Q, L10I, I15AV, K20R, E35D, M36I, N37G, R41K, R57K, Q61N, L63T, A71V, I72T, L89M, I93LF
 RenG17275RenG17275KT748303PINAM46L, I54V, V82A, L90M L10I, I13V, K14R, I15V, L19V, K20T, E35N, M36I, N37D, R41K, Q61N, A71V, I72T, T74S, L89I, I93LF
 RenG16201RenG16201KT747229PINAM46L, I54V, V82A, L90ML33F, F53L, T74TPSL10IV, G16GA, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, Q61N, I62IV, L63A, I64M, A71V, Q92KF
 RenG16095RenG16095KT747123PINAM46L, I54V, V82AL33FL10E, L24K, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, H69Y, I72TF
 RenG16431RenG16431KT747459PINAM46L L10V, T12I, I13V, G16E, E35D, M36I, R41K, R57K, Q61N, C67E, K70KR, I72T, L89MF
 RenG16923RenG16923KT747951PINAM46L, I54V, V82AL33LFK20R, E35D, M36I, R41K, R57K, Q61N, L89MF
 RenG14597RenG14597KT745625PINAM46L, I54V, V82AL33I, K43T, F53L, N83DL10I, I13V, K20R, A22V, E35D, M36I, R41K, K55R, R57RK, Q61N, A71T, I72T, T74AS, L89I, T91SF
 RenG14436RenG14436KT745464PINAM46L, G48V, I54V, V82AL24IL10V, I15V, L19I, K20R, E35D, M36I, N37D, R41K, F53Y, K55R, R57K, D60E, Q61E, I62V, L63P, A71T, I72T, T74TA, L89I, T91SF
 RenG15083RenG15083KT746111PINAM46L, N88S L10V, I15V, G16E, K20R, E35D, M36V, R41K, R57K, Q61N, L63T, E65D, I72TF
 RenG15499RenG15499KT746527PINAM46L, I50L, V82AL33FT12TS, I13IV, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, L89MF
 RenG14157RenG14157KT745185PINAM46L, G48T, I54V, L76V, V82AF53LI15V, G16E, L19I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63T, E65D, A71V, I72T, I93LF
 RenG15231RenG15231KT746259PINAM46L, I50L, V82AL33F, K43TL10V, I15V, G16E, K20R, E35N, M36I, N37NT, P39S, R41K, I62V, L63T, I64V, E65D, A71V, I72T, T74S, I93LF
 RenG13858RenG13858KT744886PINAM46L, G48GS, I54V, V82A, L90ML33LF, K43T, T74PL10V, G16E, L19I, K20R, E35D, M36V, P39T, R41K, R57K, Q61D, I62V, A71V, I72R, I93LF
 RenG15319RenG15319KT746347PINAM46L, I54V, L76LV, V82AV11VI, L24I, L33F, F53FL, T74TPL10V, I13V, G16E, L19I, K20R, E35D, M36I, N37X, P39PS, R41K, K55R, R57K, Q61D, L63E, E65D, I72IR, L89MF
 RenG14385RenG14385KT745413PINAM46L, G48Q, I54V, L76V, I84VL24IL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57RK, Q61N, L63T, I64L, I72T, V82VI, L89M, Q92QKF
 RenG14681RenG14681KT745709PINAM46L, I54V, V82A, L90ML33I, N88DL10I, I13V, G16E, G17D, L19I, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63H, A71I, L89I, I93LF
 RenG14293RenG14293KT745321PINAM46L, I54V, L76V, V82AL33FL10V, I13V, G16E, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63V, E65D, I72T, T74A, L89MF
 RenG13739RenG13739KT744767PINAM46L, I54V, V82A, L90M L10V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61D, I72T, L89IF
 RenG13624RenG13624KT744652PINAM46L, V82VA L10I, T12K, K14I, I15V, K20I, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, E65D, T74S, L89MF
 RenG14160RenG14160KT745188PINAM46L, I54V, V82AL24I, L33F, Q58EL10I, K14T, L19Q, K20R, E35D, M36I, K55R, R57K, D60E, Q61N, I62V, L63P, E65D, I72IM, L89I, Q92KF
 RenG13721RenG13721KT744749PINAM46L, I50L, V82AL24I, L33FL10V, I13V, I15V, K20R, E35D, M36I, R41K, V56VA, R57K, Q61N, L63LP, E65ED, K70KR, L89MF
 RenG13954RenG13954KT744982PINAM46L, G48V, I54V, V82SL33IL10I, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, L89MF
 RenG15021RenG15021KT746049PINAM46L, I54LV, L76V, V82AL33FL10V, I13IV, G16E, L19V, K20R, E35D, M36I, N37DE, P39PQ, K55R, R57K, Q61N, L63T, E65D, I72V, T74S, L89MF
 RenG14069RenG14069KT745097PINAD30N, M46L, V82AL24I, L33F, K43TL10I, I15IV, G16E, K20R, E35D, M36V, N37T, P39S, R41K, R57K, Q61N, I62V, L63P, A71V, V75I, V77I, I93LF
 RenG15072RenG15072KT746100PINAM46L, I54V, L76V, V82A, L90ML33F, Q58EL10V, I13V, K14R, G16E, K20R, E35D, M36I, N37E, P39S, R41RK, K55R, R57K, D60DE, Q61N, I62V, L63T, I64V, K70KT, V77IF
 RenG14675RenG14675KT745703PINAM46L, I50IL, I54V, V82AV11I, L24I, F53FL, L89LMVL10I, I15V, L19LAPV, K20M, E35N, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, A71IV, I72T, Q92KF
 RenG14136RenG14136KT745164PINAM46L, V82A, L90ML10F, L23I, L33F, Q58EI13V, I15V, K20T, E35N, M36I, R41K, G51A, D60E, Q61D, L63P, K70R, L89IF
 RenG14428RenG14428KT745456PINAM46L, I54V, V82AL24I, L33F, T74PL10V, I13V, K20KR, E35D, M36I, N37D, R41K, R57K, Q61N, L89MF
 RenG15381RenG15381KT746409PINAM46L, I54V, V82A, L90MK43TL10I, K14KR, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, L89M, I93LF
 RenG14313RenG14313KT745341PINAM46L, I54V, V82AL10F, L33F, T74PI13V, K20I, E35D, M36I, R41K, K55R, R57K, Q61N, E65D, L89MF
 RenG12432RenG12432KT743460PINAM46L, I54V, I84VL24I, G48EL10I, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, I64L, I72T, V82VI, L89M, Q92KF
 RenG11970RenG11970KT742998PINAM46L, G48MV, I54V, V82A, L90ML33LF, K43T, T74PL10V, K20R, E35D, M36I, R41K, R57K, Q61D, I62V, L63P, A71V, I72AT, L89I, T91A, I93LF
 RenG12430RenG12430KT743458PINAD30N, M46L, I50L, V82AN88DL10V, T12A, I13V, I15S, G16R, K20R, E21Q, E35D, M36I, N37T, R41K, K45R, R57K, Q61N, I62V, L63AD, A71V, I72IV, T74TS, I85IV, Q92QRF
 RenG11893RenG11893KT742921PINAM46L, I50L, V82AL33FL10I, I13IV, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, L63P, C67D, A71AT, I72RF
 RenG13532RenG13532KT744560PINAD30N, M46L, I54IV, V82A, L90ML33F, F53L, N88DL10V, T12Q, I13V, I15V, G16GE, K20R, E35D, M36I, R41K, K55KN, Q61N, L63S, I93ILF
 RenG13144RenG13144KT744172PINAM46L, I50L, V82AL33FK20R, E35D, M36I, N37I, R41K, K55KR, R57K, Q61D, T74S, L89M, I93ISF
 RenG12824RenG12824KT743852PINAD30N, M46L, I54V, V82AL33I, F53L, N83D, N88DL10I, I13V, G16E, K20R, A22V, E35N, M36I, N37T, K45R, R57K, Q61N, L63T, E65D, A71V, I72T, T74S, V75I, L89M, Q92KF
 RenG12728RenG12728KT743756PINAM46L, I54V, V82AK43TL10V, T12I, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, I62V, L63P, T74S, L89IF
 RenG11816RenG11816KT742844PINAM46L, I54V, V82A, L90M L10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, I72M, L89MF
 RenG12485RenG12485KT743513PINAM46L, I54V, V82A I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, T74S, L89IF
 RenG13415RenG13415KT744443PINAM46L, V82AL24I, T74PL10I, T12P, K14R, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, L89MF
 RenG12409RenG12409KT743437PINAM46L, I54V, I84VN83DL10I, T12I, I13V, A22V, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, K70R, T74A, L89I, T91SF
 RenG12901RenG12901KT743929PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG12441RenG12441KT743469PINAM46L, I54V, V82A, L90MK43T, T74PL10I, I15V, L19I, K20R, E35D, M36I, R41K, K55KR, R57K, Q61D, I62V, L63P, L89LM, I93LF
 RenG11986RenG11986KT743014PINAM46L, I54V, V82F, L90MF53LL10V, I15V, K20T, E35N, M36I, R41K, K55R, R57K, Q61N, I64V, G68E, A71V, V77I, I93LF
 RenG12941RenG12941KT743969PINAM46L, I54V, V82AT74TPL10V, K14R, Q18E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, E65D, L89MF
 RenG11965RenG11965KT742993PINAM46L, V82AL24I, L33F, K43T, I50M, G73ST12N, I13V, I15V, E35D, M36IL, R41K, R57K, Q61D, I62V, L63P, A71VF
 RenG12789RenG12789KT743817PINAM46L, I50L, V82A L10V, I13IV, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I64IV, K70R, A71AV, I72IV, T74S, V75VI, L89MF
 RenG12888RenG12888KT743916PINAM46L, I54V, L76V, V82A, L90ML10F, Q58EI15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, I62V, L63P, A71V, L89I, I93LF
 RenG12114RenG12114KT743142PINAM46L, I54V, V82A, L90ML33I, Q58E, N83DL10IV, I13V, K14R, K20R, E35D, M36I, N37X, R41K, K55R, R57K, D60E, I62V, L63P, A71T, L89I, T91SF
 RenG11967RenG11967KT742995PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG12340RenG12340KT743368PINAM46L, I50L, V82VA, N88SL33FL10V, I13V, I15IV, G16E, K20R, E35D, M36I, N37S, P39P*QS, R41K, K45R, R57K, Q61N, L63S, I64IV, I72TF
 RenG11946RenG11946KT742974PINAM46L, N88SQ58EL10V, K20T, E35D, M36I, R57K, Q61N, I62V, L63S, E65D, I72T, V77I, L89M, I93LF
 RenG12550RenG12550KT743578PINAM46L, I54V, V82AL24I, L33F, K43T, F53LL10V, L19I, K20R, E35D, M36I, K55R, R57K, D60E, Q61E, I62V, L63P, A71V, I93LF
 RenG12087RenG12087KT743115PINAM46L, I54V, L76V, V82MQ58EL10I, I13V, I15V, K20T, E35DN, M36I, R41K, R57K, Q61N, I62V, E65D, T74S, L89MF
 RenG12493RenG12493KT743521PINAM46L, I54V, V82A, I84VL24I, L33F, K43KTL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, I64L, E65D, A71L, I72T, T91S, I93LF
 RenG13129RenG13129KT744157PINAM46L, I54V, V82A, L90MN88DL10V, I13K, I15G, K20I, E35N, M36I, L38F, R41K, R57K, Q61H, L63I, A71T, T74S, L89I, Q92KF
 RenG10066RenG10066KT741094PINAM46L, I54V, V82AL24I, K43TL10V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, K55KR, R57K, Q61N, I62V, L63V, E65D, T74A, L89MF
 RenG10098RenG10098KT741126PINAM46L, I54V, V82AV11I, L24I, K43TL10V, I13V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71T, I72TF
 RenG10988RenG10988KT742016PINAM46L G17E, K20R, E35D, M36I, R41K, R57K, Q61N, L63I, L89M, I93LF
 RenG11775RenG11775KT742803PINAM46L, I54V, L76LV, V82A, L90M L10V, K14R, I15V, G16E, K20MT, E35N, M36I, N37D, R41K, K55KR, R57K, Q61N, I62IV, L63HP, T74S, V77VI, I85V, L89I, I93LF
 RenG10941RenG10941KT741969PINAM46L, I54V, V82AL24I, L33F, T74PL10I, I13IV, I15IK, K20R, E35D, M36I, R41RK, K43S, R57K, Q61N, I62V, L63P, I64M, A71V, L89LIM, I93LF
 RenG11454RenG11454KT742482PINAM46L, G48A, I54V, V82AL24I, F53LL10I, I15V, L19LV, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, T74A, L89MF
 RenG11352RenG11352KT742380PINAM46L, I54V, V82A, L90M L10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, I72M, L89MF
 RenG10810RenG10810KT741838PINAM46L, I54V, V82AL24I, L33F, K43T, T74PW6L, L10V, I13V, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, I72T, L89MF
 RenG10500RenG10500KT741528PINAM46L, G48EQ, L90MF53LL10V, I13IV, K14R, G17D, K20T, E35D, M36I, N37D, R41K, R57K, D60DE, Q61N, I64V, E65D, A71V, I72IV, T74TS, V77I, L89M, I93LF
 RenG11633RenG11633KT742661PINAM46L, N88SQ58EL10V, I13V, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, V77I, L89MF
 RenG11079RenG11079KT742107PINAM46L, V82AL24IL10I, I15V, L19V, K20KR, E35D, M36I, P39S, R41K, K55R, R57K, I62V, L63P, A71V, L89LM, I93LF
 RenG10321RenG10321KT741349PINAM46L, I50V, V82AV11I, L24I, L33F, K43T, F53FL, T74P, L89EIKVL10I, I13V, I15V, K20R, E35D, M36I, N37DE, R41K, R57K, Q61N, I62V, L63LP, G68GE, A71V, I93LF
 RenG10867RenG10867KT741895PINAM46L, I54V, V82AL24IL10V, I15V, L19LI, K20R, E35D, M36I, K43PQ, K55R, R57K, Q61HN, L63PF
 RenG10926RenG10926KT741954PINAM46L, I54V, V82A, L90MV11VI, K43KT, F53FL, G73SL10I, T12N, I15V, L19IMT, K20I, E35N, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, H69Y, A71T, I72T, I85IVF
 RenG10694RenG10694KT741722PINAM46L, L90M T4TA, R8RG, L10V, T12N, L19Q, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L89M, I93LF
 RenG10261RenG10261KT741289PINAM46L, I50L, V82AL33FK20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I93LF
 RenG10201RenG10201KT741229PINAM46L, I54IV, V82A, L90LML33LFL10I, I13V, I15IV, Q18H, K20KEMV, M36MI, N37E, K43RS, K55KR, R57K, D60E, Q61D, L63P, V77VI, P79PS, L89IMF
 RenG10210RenG10210KT741238PINAM46L, G48GA, I54V, V82ASL24IL10I, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71AV, T74TS, V77VI, L89M, I93LF
 RenG10216RenG10216KT741244PINAM46L, V82A L10V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, L89MF
 RenG10503RenG10503KT741531PINAM46L, I54V, V82A L10I, I15V, K20R, E35D, M36I, R41K, K55R, L63P, I85V, L89M, I93LF
 RenG10170RenG10170KT741198PINAM46L, I54V, V82A L10I, I13V, G16E, K20R, M36I, N37ND, R41K, Q61N, L63T, I64IL, E65ED, L89MF
 RenG11711RenG11711KT742739PINAM46L, I54V, V82AL24I, L33F, K43T, G48E, F53LL10I, I15V, K20M, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, T74S, L89I, Q92KF
 RenG10996RenG10996KT742024PINAM46L, V82A L10V, T12N, I15V, L19I, K20R, M36I, N37E, R41K, I62V, L63S, H69Q, L89LMF
 RenG11703RenG11703KT742731PINAM46L, I54V, V82F, L90MF53LL10V, K20R, E35D, M36V, N37NT, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64IV, A71AITV, I72IV, V77I, I85IV, L89IM, I93LF