<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation K43R
Rx PI-naive
IncludeMixtures No
References 16
Patients 30
Isolates 30
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Belec (2000)r31r31_m0AF204351None   I15V, Q18E, E35D, M36I, R41K, K43R, R57KF
Kijak (2001)ARG04ARG04PRAF328565None   K14R, I15V, E35D, M36I, R41K, K43R, R57K, Q61NF
 ARG05ARG05PRAF328566None   E35D, M36I, R41K, K43R, R57K, Q61NF
Brindeiro (2003)BRP2146BRP2146AY213449None   L10I, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, E65D, V77I, L89M, I93LF
Eshleman (2004)BrRJ126BrRJ126AY444278None   I15IV, E35D, M36I, R41K, K43R, R57K, Q61S, H69Y, L89MF
 3934039340AY444291None   I13V, I15V, L19I, E35D, M36I, R41K, K43R, R57K, Q61N, L63LP, H69Y, I72T, L89MF
Non-B Workgroup (2005)BR1052BR1052AY900940None   L10V, I15V, E35D, M36I, R41K, K43R, R57K, Q61N, L63S, I72T, C95SF
de Sa Filho (2006)BREPM13853BREPM13853DQ085875None   G17D, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, I72RF
Petroni (2006)AP_ARRP015AP_ARRP015DQ206653None   I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63Q, I72E, Q92KF
 AP_ARRP051AP_ARRP051DQ345501None   K14R, I15V, E35D, M36I, N37D, K43R, R57K, Q61D, I72ITF
Dilernia (2007)F006F006EF120077None   L10V, K14KR, I15V, M36I, R41K, K43R, Q61N, L63P, I72V, Q92TF
 F237F237EF120191None   L10IV, I13V, G16E, K20R, M36I, R41K, K43R, R57K, D60E, Q61D, C67Y, I72TF
 F339F339EF120240None   I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63Q, I72E, Q92KF
 N51N51EF120308None   I15V, E35D, M36I, R41K, K43R, R57K, Q61NF
 N03N03EF120353None   I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63Q, I72E, Q92KF
Rios (2007)CH110MR_CH110EF194012None   L10V, I15V, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, L89M, I93LF
Cardoso (2009)BRGO3133BRGO3133FJ594169None   E35D, M36I, R41K, K43R, R57K, Q61D, L63A, E65D, L89MF
Cuevas (2009)P1708P1708.1EU822753None   K14R, I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, C67CS, L89MF
Vercauteren (2009)pt19481571549513GQ399076None   L10V, T12H, I15V, G16GE, E35D, M36I, N37ND, R41K, K43R, R57K, Q61N, L63Q, E65DF
 pt13225268793849GQ399702None   L10V, T12H, I15V, E35D, M36I, R41K, K43R, R57K, Q61N, L63Q, E65DF
 pt7528640409048GQ400272None   L10V, T12K, I15V, K20R, E35D, M36I, N37D, R41K, K43R, I62V, L63P, H69HQ, T74A, L89MF
Djoko (2010)603CD4751FR666603None   G16E, K20R, E35D, M36I, P39S, R41K, K43R, Q61H, I62V, L63T, E65D, H69K, T74S, L89MF
 618CD3355FR666618None   L10V, T12S, I15V, G16E, K20R, E35D, M36I, P39S, R41K, K43R, L63T, H69K, L89MF
Aulicino (2011)190-774190-774HQ158199None   I15V, G17D, K20M, E35D, M36I, R41K, K43R, R57K, Q61N, I93LF
 42-A24342-A243HQ158247None   I15V, E35D, M36I, R41K, K43R, R57K, Q61N, I72M, L89MF
 522-B506522-B506HQ158252None   K14R, I15V, E35D, M36I, R41K, K43R, R57K, Q61N, I72TF
 94-66194-661HQ158265None   T12A, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, V77I, I93LF
Frentz (2013)EHR-61454EHR-61454JX300566None   L10V, K14R, E35D, M36I, R41K, K43R, R57K, Q61N, L63S, H69Q, V77I, L89MF
 EHR-86876EHR-86876JX301011None   L10LI, T12K, I15V, L19I, E35D, M36I, R41K, K43R, R57K, L63V, E65DF
Temereanca (2013)SR26SR26JX966503None   I15V, G16E, E35D, M36I, R41K, K43R, R57K, L63T, E65D, I72T, L89M, I93MF